**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 10061-01-5 |Z-1,3-Dichloropropene | 100 | 233-195-8 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: T N
Risk Phrases: 10 20/21 25 36/37/38 43 50/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Flammable. Harmful by inhalation and in contact with skin. Toxic if
swallowed. Irritating to eyes, respiratory system and skin. May
cause sensitization by skin contact. Very toxic to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
Potential Health Effects
Eye:
Vapors cause eye irritation. Lachrymator (substance which
increases the flow of tears). May cause severe eye irritation and
possible injury. May cause temporary corneal clouding and
ulceration.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Prolonged or widespread skin contact may result in the material being
absorbed in harmful amounts.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with
nausea, vomiting and diarrhea. Ingestion of large amounts may cause
CNS depression.
Inhalation:
Causes respiratory tract irritation. Causes narcotic effects
including headache, dizziness, weakness, unconsciousness, and
possible death. Effects of inhalation may be delayed. Easily
attainable vapor concentrations may cause serious adverse effects,
even death.
Chronic:
Possible cancer hazard based on tests with laboratory animals. May
cause liver and kidney damage.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
POISON material. If inhaled, get medical aid immediately. Remove
victim to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Use water spray to keep fire-exposed containers
cool. Flammable liquid and vapor. May accumulate static electrical
charges, and may cause ignition of its own vapors. Fire or excessive
heat may result in violent rupture of the container due to bulk
polymerization. Approach fire from upwind to avoid hazardous vapors
and toxic decomposition products. Vapors are heavier than air and may
travel to a source of ignition and flash back. Vapors can spread
along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation.
Evacuate unnecessary personnel. Approach spill from upwind.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Do not
get in eyes, on skin, or on clothing. Empty containers retain product
residue, (liquid and/or vapor), and can be dangerous. Keep away from
heat, sparks and flame. Do not pressurize, cut, weld, braze, solder,
drill, grind, or expose empty containers to heat, sparks or open
flames. Do not breathe vapor or mist. Use only with adequate
ventilation or respiratory protection. This product is corrosive to
some metals. Do not use containers or equipment containing aluminum,
magnesium, zinc, cadmium, or other alloys.
Storage:
Keep away from sources of ignition. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Do not store in aluminum containers.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Facilities storing or utilizing this material should
be equipped with an eyewash facility and a safety shower. Ventilation
fans and other electrical service must be non-sparking and have an
explosion-proof design.
Exposure Limits
CAS# 542-75-6:
Belgium - TWA: 1 ppm VLE; 4.6 mg/m3 VLE
Germany: 0.11 ppm TWA; 0.5 mg/m3 TWA
Germany: Skin absorber
Malaysia: 1 ppm TWA; 4.5 mg/m3 TWA
Netherlands: 1 ppm MAC; 5 mg/m3 MAC
Russia: 5 mg/m3 TWA
Spain: 1 ppm VLA-ED; 4.6 mg/m3 VLA-ED
CAS# 10061-01-5:
Belgium - TWA: (listed as 1,3-dichloropropene): 1 ppm VLE; 4.6 mg
VLE
Germany: (listed as 1,3-dichloropropene): Skin absorber
Malaysia: (listed as 1,3-dichloropropene): 1 ppm TWA; 4.5 mg/m3 T
Netherlands: (listed as 1,3-dichloropropene): 1 ppm MAC; 5 mg/m3
Russia: (listed as 1,3-dichloropropene): 5 mg/m3 TWA
Spain: (listed as 1,3-dichloropropene): 1 ppm VLA-ED; 4.6 mg/m3
VLA-ED
Personal Protective Equipment
Eyes:
Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin
exposure. Use polyvinyl alcohol or fluorocarbon
rubber (viton) gloves.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use. Wear a NIOSH/MSHA
or European Standard EN 149 approved full-facepiece
airline respirator in the positive pressure mode with
emergency escape provisions.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: clear straw colored
Odor: sweetish odor - pungent odor - penetrating odor
pH: Not applicable.
Vapor Pressure: 30 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 108 deg C @ 760 mmHg
Freezing/Melting Point: -60 deg C
Autoignition Temperature: Not available.
Flash Point: 27 deg C ( 80.60 deg F)
Explosion Limits, lower: 5.50 vol %
Explosion Limits, upper: 14.50 vol %
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density: 1.2000g/cm3
Molecular Formula: C3H4Cl2
Molecular Weight: 110.97
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
May polymerize.
Conditions to Avoid:
Ignition sources, excess heat, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, aluminum, magnesium.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 542-75-6: UC8310000
CAS# 10061-01-5: UC8325000
LD50/LC50:
CAS# 542-75-6: Inhalation, mouse: LC50 = 3220 mg/m3/2H; Oral, mouse:
LD50 = 640 mg/kg; Oral, rat: LD50 = 470 mg/kg; Skin, rabbit: LD50 =
333 mg/kg; Skin, rat: LD50 = 775 mg/kg.
CAS# 10061-01-5.
Toxicity data from Dow AgroSciences:
(rat) is 300 mg/kg (male), and 224 mg/kg (female).
Vapor LC50 (rat) (male) is 855 to 1035 ppm for 4 hours; Vapor LC50
(rat) (female) is 904 ppm for 4 hours.
Carcinogenicity:
1,3-Dichloropropene, mixed isomers -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 1/1/89
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Z-1,3-Dichloropropene -
California: carcinogen, initial date 1/1/89 (listed as 1,3-Dichloropro
NTP: Suspect carcinogen (listed as 1,3-Dichloropropene).
IARC: Group 2B carcinogen (listed as 1,3-Dichloropropene).
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 4.1 mg/L; 96 Hr.; Static Conditions; 18
degrees CFish: Rainbow trout: LC50 = 5.9 mg/L; 96 Hr.; Static
Conditions; 11-13 degrees CFish: Bluegill/Sunfish: LC50 = 6.1 mg/L;
96 Hr.; Static Conditions; 21-23 degrees CWater flea Daphnia: EC50 =
6.15 mg/L; 48 Hr.; Static Conditions; 21-23 degrees CBacteria:
Phytobacterium phosphoreum: EC50 = 5.1 mg/L; 30 minutes; Microtox
testAlgae: EC50 = 4.95 mg/L; 96 Hr.; None
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: Toxic Liquid, Flammable, Organic, N.O.S.
Hazard Class: 6.1 (3)
UN Number: 2929
Packing Group: II
IMO
Shipping Name: Toxic Liquid, Flammable, Organic, N.O.S.
Hazard Class: 6.1 (3)
UN Number: 2929
Packing Group: II
RID/ADR
Shipping Name: Toxic Liquid, Flammable, Organic, N.O.S.
Hazard Class: 6.1 (3)
UN Number: 2929
Packing group: II
USA RQ: CAS# 542-75-6: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 10 Flammable.
R 20/21 Harmful by inhalation and in contact with
skin.
R 25 Toxic if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 43 May cause sensitization by skin contact.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 542-75-6: 3
CAS# 10061-01-5: No information available.
Canada
CAS# 542-75-6 is listed on Canada's NDSL List.
CAS# 542-75-6 is listed on Canada's Ingredient Disclosure List.
CAS# 10061-01-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 542-75-6 is listed on the TSCA inventory.
CAS# 10061-01-5 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 10/23/1998 Revision #3 Date: 5/10/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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