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MSDS 
:
 Ftorafur, 99%
CAS 
:
 17902-23-7
SYNONYMS 
:
 1-(2-Tetrahydrofuryl)-5-fluorouracil;     1-(Tetrahydrofuran-2-yl)-5-fluorouracil; 2,4(1H,3H)-Pyrimidinedione,     5-fluoro-1-(tetrahydro-2-furanyl)-;     5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione;     5-Fluoro-1-(tetrahydro-2-furyl)uracil;     5-Fluoro-1-(tetrahydro-3-furyl)uracil;     5-Fluoro-1-(tetrahydrofuran-2-yl)uracil; Pyrimidine-deoxyribose     N1-2'-furanidyl-5-fluorouracil; Uracil,     1-(tetrahydrofuran-2-yl)-5-fluoro-; Uracil,     5-fluoro-1-(tetrahydro-2-furyl)-
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 17902-23-7 |2,4(1H,3H)-pyrimidinedione,5-fluoro-1-| 99 | 241-846-2 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Harmful.

Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May be harmful if swallowed. May cause encephalitis, muscular
contractions, bone marrow depression, and neurological effects.
Inhalation:
No information available.
Chronic:
No information found.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid immediately. Do NOT induce vomiting. If conscious and alert,
rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician:

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry
chemical, carbon dioxide, or appropriate foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal. Avoid
generating dusty conditions. Provide ventilation.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Do not ingest or inhale.
Storage:
Store in a tightly closed container. Store in a cool, dry area away
from incompatible substances.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use process enclosure,
local exhaust ventilation, or other engineering controls to control
airborne levels.
Exposure Limits
CAS# 17902-23-7:


Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Crystalline powder
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 167.00 - 169.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble in hot water.
Specific Gravity/Density: Not available.
Molecular Formula: C8H9FN2O3
Molecular Weight: 200.17

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 17902-23-7: YR0450000
LD50/LC50:
CAS# 17902-23-7: Oral, mouse: LD50 = 775 mg/kg; Oral, rabbit: LD50 =
44 mg/kg; Oral, rat: LD50 = 930 mg/kg.
Carcinogenicity:
2,4(1H,3H)-pyrimidinedione,5-fluoro-1-(tetrahydro-2-furanyl) -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****



**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 17902-23-7: No information available.
Canada
CAS# 17902-23-7 is listed on Canada's NDSL List.
CAS# 17902-23-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 17902-23-7 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

MSDS Creation Date: 9/02/1997 Revision #4 Date: 3/18/2003

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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