**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 313-67-7 |Aristolochic acid I | 50 | 206-238-3 |
|----------------|--------------------------------------|----------|-----------|
| 475-80-9 |Aristolochic acid II | 50 | 207-499-6 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: T
Risk Phrases: 23/24/25 36/37/38 45 68
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin. May cause
cancer.Possible risk of irreversible effects.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause kidney damage.
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. May cause
kidney damage.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Keep container tightly closed. Avoid ingestion and
inhalation.
Storage:
Store in a cool, dry place. Do not store in direct sunlight. Store
in a tightly closed container. Store at room temperature or below.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 313-67-7:
CAS# 475-80-9:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: orange-yellow
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 260-265 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 281-286 deg C
Solubility in water: Slightly soluble.
Specific Gravity/Density:
Molecular Formula: C17H11NO7
Molecular Weight: 341.27
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 313-67-7: CF3325000
CAS# 475-80-9: SF8281600
LD50/LC50:
CAS# 313-67-7: Oral, mouse: LD50 = 55900 ug/kg; Oral, rat: LD50 =
184 mg/kg.
CAS# 475-80-9.
Carcinogenicity:
Aristolochic acid I -
California: carcinogen, initial date 7/9/04 (listed as Aristolochic ac
IARC: Group 2A carcinogen (listed as Aristolochic acids (natural
Aristolochic acid II -
California: carcinogen, initial date 7/9/04 (listed as Aristolochic ac
IARC: Group 2A carcinogen (listed as Aristolochic acids (natural
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ALKALOID SALTS, SOLID, N.O.S.*
Hazard Class: 6.1
UN Number: 1544
Packing Group: I
IMO
Shipping Name: ALKALOID SALTS, SOLID, N.O.S.
Hazard Class: 6.1
UN Number: 1544
Packing Group: I
RID/ADR
Shipping Name: ALKALOID SALTS, SOLID, N.O.S.
Hazard Class: 6.1
UN Number: 1544
Packing group: I
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 45 May cause cancer.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 68 Possible risk of irreversible effects.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 313-67-7: No information available.
CAS# 475-80-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 313-67-7 is not listed on Canada's Ingredient Disclosure List.
CAS# 475-80-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 313-67-7 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 475-80-9 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 9/02/1997 Revision #6 Date: 2/14/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
Vinyl Acetate
| 108-05-4 |
|
Dichlorophenylphosphine, 97%
| 644-97-3 |
|
5-Nitro-2-N-(Propylamino)Pyridine
| 25948-11-2 |
|
Ethyl cellulose, Ethoxyl Content 48%, 4 CPS
| 9004-57-3 |
|
Crotyl alcohol, 90% (gc)
| 6117-91-5 |
|
Lead(ii) methanethiolate, 99% (titr.)
| 35029-96-0 |
|
3-exo-Hydroxymethylbicyclo[2.2.1]heptyl-2-exo-amine hydrochloride,
| |
|
4,4'-Sulfonyldiphenol, 99.7% (HPLC)
| 80-09-1 |
|
(Diphenylthiocarbazono)phenylmercury
| 56724-82-4 |
|
3-Iodotoluene, 99%
| 625-95-6 |
|
1(2-Methoxyphenyl)piperazine hydrochloride, 99%(tlc)
| 5464-78-8 |
|
3,3-Dimethyl-1-Butene, 95%
| 558-37-2 |
|
Benzyltriethylammonium chloride, 98%
| 56-37-1 |
|
1-Cyclohexene-1-carboxylic acid, 96% (GC)
| 636-82-8 |
|
4-Bromo-2-Fluorobenzonitrile, 99+%
| 105942-08-3 |
|
Eicosanoic acid, 99%
| 506-30-9 |
|
2,3-Dichlorotoluene, 98%
| 32768-54-0 |
|
3-Methoxy-1-butanol, 99%
| 2517-43-3 |
|
Germanium Tetrachloride, 99.99%
| 10038-98-9 |
|
2-Naphthaldehyde, 98%
| 66-99-9 |
|
1-Pentanesulfonic acid sodium salt premixed concentrate (Low UV)
| 67-56-1 |
|
Cis-1,2-Cyclohexanedimethanol, 98%
| 15753-50-1 |
|
Tetrabutylammonium Bromide,99% (titr.)
| 1643-19-2 |
|
N,N'-Bis(Phenylmethylene)-1,2-Ethylenediamine, 99.5+%
| 0-01-1 |
|
Wood's Metal
| 7439-92-1 |
|
N,N-Diethyldodecanamide, 98+%
| 3352-87-2 |
|
Thiocarbanilide, 98%
| 102-08-9 |
|
2-Hydroxy-5-nitropyridine, 99+%
| 5418-51-9 |
|
Xylenes, mixed isomers with ethylbenzene (Flash Point 26.1C / 79F;
| 100-41-4 |
|
Xylenol Orange Tetrasodium Salt
| 3618-43-7 |
|
Nile Red, 99% (UV-VIS)
| 7385-67-3 |
|
1-Aminoindan, 99%
| 34698-41-4 |
|
4-Fluorobenzyl Alcohol, 98%
| 459-56-3 |
|
Brilliant Sulphaflavine
| 2391-30-2 |
|
4,4'-Diaminostilbene-2,2'-Disulfonic Acid, 95% (UV-Vis)
| 81-11-8 |
|
n-Methylacetoacetamide, 70 wt % aqueous solution
| 7732-18-5 |
|
Zinc Metal Powder
| 7440-66-6 |
|
cis-1,2-Cyclohexanedicarboxylic anhydride, 99%
| 13149-00-3 |
|
5-Methoxy-2-Methylbenzothiazole
| 2941-69-7 |
|
Zinc acetate dihydrate
| 557-34-6 |
|
Methyl Yellow, indicator grade
| 60-11-7 |
|
Aristolochic acid, mixture of I and II (approx. 1:1)
| 313-67-7 |
|
Ethyl 5-bromo-2-chlorobenzoate, 97%
| 76008-73-6 |
|
Butyl stearate, mixture of ca. 55-65% stearyl- and 25-40% cetyl-
| 111-06-8 |
|
Zinc bromide
| 7699-45-8 |
|
Zinc Carbonate
| 3486-35-9 |
|
(r)-(-)-2-Amino-3-methyl-1-butanol
| 4276-09-9 |
|
Alpha-Fluorocinnamic Acid, 98%
| 350-90-3 |
|
Zinc chloride
| 7646-85-7 |
|
(Iodomethyl)trimethylsilane, 99%
| 4206-67-1 |
|
|