**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 51-52-5 |Propylthiouracil | 98 | 200-103-2 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 33
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Danger of cumulative effects.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. If absorbed, may cause symptoms similar
to those for ingestion. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if
swallowed. The most serious reaction to propylthiouracil is
agranulocytosis, a severe decrease in the number of white blood cells
that are a part of the immune system. Symptoms are sore throat and/or
fever, and oral ulcers.
stiffness in the joints, paresthesias, headache, nausea, and loss or
depigmentation of hair. Other effects include pulmonary lesions,
hepatitis and nephritis.
Inhalation:
May cause respiratory tract irritation. May cause effects similar to
those described for ingestion. May be harmful if inhaled.
Chronic:
Prolonged or repeated exposure may cause thyroid inhibition.
Propylthiouracil has induced malignant thyroid tumors in experimental
animals. There are no adequate data available to evaluate the
carcinogenicity of PTU in humans.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. This
material in sufficient quantity and reduced particle size is capable
of creating a dust explosion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Avoid generating dusty conditions. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.
Hormones and antibiotics room. Store protected from light and air.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use process enclosure,
local exhaust ventilation, or other engineering controls to control
airborne levels.
Exposure Limits
CAS# 51-52-5:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystalline powder
Color: white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 218.00 - 220.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 0.1% @ 20C
Specific Gravity/Density:
Molecular Formula: C7H10N2OS
Molecular Weight: 170.23
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Light, prolonged exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and
toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 51-52-5: YR1400000
LD50/LC50:
CAS# 51-52-5: Oral, rat: LD50 = 1250 mg/kg.
Carcinogenicity:
Propylthiouracil -
California: carcinogen, initial date 1/1/88
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 33 Danger of cumulative effects.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 51-52-5: 1
Canada
CAS# 51-52-5 is listed on Canada's NDSL List.
CAS# 51-52-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 51-52-5 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #5 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
Sodium Chlorate
| 7775-09-9 |
|
Sodium chloride
| 7647-14-5 |
|
Glycyl-L-glutamine monohydrate, 99%
| 13115-71-4 |
|
2-Bromoethyl Ethyl Ether, Tech., 94% (GC)
| 592-55-2 |
|
Sodium chromate, anhydrous
| 7775-11-3 |
|
(R,S)-2-Amino-3-hydroxy-3-methylbutanoic acid, 99+%
| 2280-28-6 |
|
Sodium Citrate Dihydrate
| 6132-04-3 |
|
Sodium Cobaltinitrite
| 13600-98-1 |
|
Triphenyl phosphite, 99+%
| 101-02-0 |
|
4-Butylphenol, 99% (gc)
| 1638-22-8 |
|
2,2,2-Triphenylacetophenone, 99+%(TLC)
| 466-37-5 |
|
Sodium Cyanide
| 143-33-9 |
|
Sodium Chloranilate Trihydrate, 95% (UV-Vis)
| 36275-66-8 |
|
2,3,4,5-Tetrachloronitrobenzene, 99%
| 879-39-0 |
|
Dimethyl Malonate, 99+%
| 108-59-8 |
|
2-(Methacryloyloxy)ethyltrimethylammonium methyl sulfate, 80% in
| 6891-44-7 |
|
Sodium dichromate dihydrate
| 7789-12-0 |
|
2-Phenyl-1-propanol, 97%
| 1123-85-9 |
|
N-Carbobenzyloxy-L-Serine, 99+%
| 1145-80-8 |
|
Sodium fluoride
| 7681-49-4 |
|
Triphenylantimony, 97%
| 603-36-1 |
|
Sodium Formate
| 141-53-7 |
|
Sodium Metaphosphate
| 10124-56-8 |
|
trans-2-Pentenoic acid, 97%
| 13991-37-2 |
|
3-Acetylindole, 97%
| 703-80-0 |
|
Sodium hydroxide, solid
| 497-19-8 |
|
3,5-Dimethyl-2-cyclohexen-1-one, 99%
| 1123-09-7 |
|
Sodium hypophosphite monohydrate
| 7681-53-0 |
|
Sodium iodate
| 7681-55-2 |
|
Sodium Iodide, Anhydrous, 99+%
| 7681-82-5 |
|
1,1'-(4-Chlorobutylidene)bis-(4-fluorobenzene) tech. 90+%
| 3312-04-7 |
|
Sodium Lactate
| 72-17-3 |
|
Sodium arsenite, powder, certified
| 7784-46-5 |
|
Sodium metabisulfite
| 7446-09-5 |
|
2,6-Dichloropyrazine, 99+%
| 4774-14-5 |
|
Sodium meta-Silicate Nonahydrate
| 6834-92-0 |
|
Sodium meta-Silicate Pentahydrate
| 6834-92-0 |
|
Sodium Methoxide
| 124-41-4 |
|
Sodium Nitrate
| 7631-99-4 |
|
Octanoic Acid, 99.5+%
| 124-07-2 |
|
Sodium nitrite
| 7632-00-0 |
|
4-Hydroxy-2-mercapto-6-propylpyrimidine, 98%
| 51-52-5 |
|
1-Phenyl-1-cyclopropanecarboxylic acid, 97%
| 6120-95-2 |
|
4,4'-Dimethoxybenzhydrol, 98+%
| 728-87-0 |
|
1,1-Dimethylpropargylamine, 90% ( remainder water)
| 2978-58-7 |
|
Diethyldithiocarbamic Acid, Sodium Salt Trihydrate, Reagent ACS
| |
|
Vinyltriphenylphosphonium bromide, 97%
| 5044-52-0 |
|
Mucic Acid, 98%
| 526-99-8 |
|
Sodium oxalate
| 62-76-0 |
|
2-Hydroxyethylhydrazine, 90%
| 109-84-2 |
|
|