**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 538-75-0 |N,N'-Dicyclohexylcarbodiimide | 20.6 | 208-704-1 |
|----------------|--------------------------------------|----------|-----------|
| 872-50-4 |N-Methylpyrrolidone | 79.4 | 212-828-1 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 21 36/38 41 43
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful in contact with skin. Irritating to eyes and skin. Risk of
serious damage to eyes. May cause sensitization by skin contact.
Potential Health Effects
Eye:
Causes eye irritation. Risk of serious damage to eyes.
Skin:
Causes skin irritation. Harmful if absorbed through the skin. May
cause sensitization by skin contact.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Adverse
reproductive effects have been reported in animals.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Will burn
if involved in a fire.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion
and inhalation. Use with adequate ventilation. Wash clothing before
reuse.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 538-75-0:
CAS# 872-50-4:
United Kingdom, WEL - TWA: 25 ppm TWA; 103 mg/m3 TWA
United Kingdom, WEL - STEL: 75 ppm STEL; 309 mg/m3 STEL
Germany: 19 ppm TWA (steam); 80 mg/m3 TWA (steam)
Germany: Skin absorber
Japan: 1 ppm OEL; 4 mg/m3 OEL
Netherlands: 20 ppm MAC; 80 mg/m3 MAC (fume)
Russia: 100 mg/m3 TWA
Spain: 25 ppm VLA-ED; 103 mg/m3 VLA-ED
Spain: 75 ppm VLA-EC; 309 mg/m3 VLA-EC
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: Clear
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Not currently available.
Conditions to Avoid:
Excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 538-75-0: FF2160000
CAS# 872-50-4: UY5790000
LD50/LC50:
CAS# 538-75-0: Dermal, guinea pig: LD50 = 10 mL/kg; Inhalation, rat:
LC50 = 159 mg/m3/6H; Oral, mouse: LD50 = >800 mg/kg; Oral, rat: LD50
= 400 mg/kg.
CAS# 872-50-4: Draize test, rabbit, eye: 100 mg Moderate; Oral,
mouse: LD50 = 5130 mg/kg; Oral, rat: LD50 = 3914 mg/kg; Skin,
rabbit: LD50 = 8 gm/kg.
Carcinogenicity:
N,N'-Dicyclohexylcarbodiimide -
Not listed by ACGIH, IARC, or NTP.
N-Methylpyrrolidone -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
IMO
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
RID/ADR
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 21 Harmful in contact with skin.
R 36/38 Irritating to eyes and skin.
R 41 Risk of serious damage to eyes.
R 43 May cause sensitization by skin contact.
Safety Phrases:
S 24 Avoid contact with skin.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 41 In case of fire and/or explosion do not breathe
fumes.
WGK (Water Danger/Protection)
CAS# 538-75-0: 2
CAS# 872-50-4: 1
Canada
CAS# 538-75-0 is listed on Canada's DSL List.
CAS# 872-50-4 is listed on Canada's DSL List.
CAS# 538-75-0 is not listed on Canada's Ingredient Disclosure List.
CAS# 872-50-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 538-75-0 is listed on the TSCA inventory.
CAS# 872-50-4 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 1/16/2002 Revision #2 Date: 3/01/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
2-(3,4-Dimethoxyphenyl)-Ethylamine, 98%
| 120-20-7 |
|
2-Bromo-9-Fluorenone, 95%
| 3096-56-8 |
|
Potassium trihydrogen dioxalate dihydrate, 99%
| 6100-20-5 |
|
2-Chloromethyl-5-(4-Methoxyphenyl)-1,2,4-Oxadiazole, 98%
| 24023-71-0 |
|
2-Chloromethyl-5-(4-Chlorophenyl)-1,2,4-Oxadiazole, 98%
| 24068-15-3 |
|
Tetramethylgermanium, 97%
| 865-52-1 |
|
Phenyltosylate
| 640-60-8 |
|
Tetra-n-butylammonium hexafluorophosphate, 98%
| 3109-63-5 |
|
4-Methyl-2-nitrophenol, 99%
| 119-33-5 |
|
Tetraphenylgermanium, 97%
| 1048-05-1 |
|
2,3-Dibromopropionic Acid, 99%
| 600-05-5 |
|
Magnesium trifluoromethanesulfonate, 98%
| 60871-83-2 |
|
Tetraethyl orthocarbonate, 97%
| 78-09-1 |
|
N-(8-Bromooctyl)phthalimide
| 17702-83-9 |
|
4-Chloro-2-nitrophenol, 98%
| 89-64-5 |
|
cis-N-(4-Chlorobutenyl)Phthalimide, 97%
| 84347-67-1 |
|
4-Fluoro-o-xylene, 98%
| 452-64-2 |
|
2-Phenylglutaric anhydride, 97%
| 2959-96-8 |
|
Methyl tiglate, 98%
| 6622-76-0 |
|
Lobeline sulfate, 99%
| 134-64-5 |
|
Methyl triphenylarsonium iodide, 98%
| 1499-33-8 |
|
Hexa-n-butylditin, 98%
| 813-19-4 |
|
Hydrocortisone, 98%
| 50-23-7 |
|
Benzylurea, 93%
| 538-32-9 |
|
Dichloromethane, peptide synthesis grade, stabilized
| 75-09-2 |
|
N,N-Dicyclohexylcarbodiimide, 0.1M solution in dichloromethane,
| 75-09-2 |
|
N,N'-Dicyclohexylcarbodiimide, 1M solution in N-methylpyrrolidone,
| 538-75-0 |
|
N,N-Dimethylformamide, peptide synthesis grade
| 68-12-2 |
|
1,1,1,3,3,3-Hexafluoro-2-propanol, peptide synthesis grade
| 920-66-1 |
|
alpha,alpha,alpha',alpha',-Tetrachloro-p-xylene
| 7398-82-5 |
|
Bromine Water
| 7726-95-6 |
|
1,1,1,3,3,3-Hexafluoro-2-propanol, 10% in dichloromethane, peptide
| 75-09-2 |
|
1-Methyl-2-pyrrolidone, special automatic peptide synthesizer grade
| 872-50-4 |
|
N-Methylpyrrolidone, peptide synthesis grade
| 872-50-4 |
|
Methylsulfoxide, peptide synthesis grade
| 67-68-5 |
|
Ferrocene, 98%
| 102-54-5 |
|
1,2-Diiodotetrafluoroethane, 98%
| 354-65-4 |
|
5-Chlorothiophene-2-carboxylic acid, 98%
| 24065-33-6 |
|
trans-4-Methoxycinnamaldehyde, 98%
| 24680-50-0 |
|
trans-2-Methyl-2-butenal
| 497-03-0 |
|
Ethyl 3-phenylpropionate, 98%
| 2021-28-5 |
|
Allyl chloroformate, 97%
| 2937-50-0 |
|
2-Amino-3,3-dimethylbutane, 98%
| 3850-30-4 |
|
4-Tert-Butylbenzonitrile, 98%
| 4210-32-6 |
|
3-Aminopropionitrile, stabilized, 98%
| 151-18-8 |
|
4-Chlorophenylsulfonylacetonitrile, 98%
| 1851-09-8 |
|
p-Toluenesulfonylacetonitrile, 98%
| 5697-44-9 |
|
Methyl thiophene-2-carboxylate, 98%
| 5380-42-7 |
|
n-Amylbenzoate, 98%
| 2049-96-9 |
|
Isosorbide, 98%
| 652-67-5 |
|
|