**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 68-12-2 |N,N-Dimethylformamide | | 200-679-5 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 20/21 36 61
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation and in contact with skin. Irritating to eyes.
May cause harm to the unborn child.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Substance is rapidly absorbed through the skin.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause kidney damage. May cause liver damage.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation. May
cause effects similar to those described for ingestion.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause dermatitis.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting
unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Will burn if involved in a fire. Combustible
liquid.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry
chemical, or carbon dioxide.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Do not flush into a sewer. Remove
all sources of ignition.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Use only in a well-ventilated area. Use spark-proof tools and
explosion proof equipment. Avoid breathing dust, vapor, mist, or
gas. Avoid contact with skin and eyes. Use only in a chemical fume
hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 68-12-2:
United Kingdom, OES - TWA: 10 ppm TWA; 30 mg/m3 TWA
United Kingdom, OES - STEL: 20 ppm STEL; 61 mg/m3 STEL
United States OSHA: 10 ppm TWA; 30 mg/m3 TWA
Belgium - TWA: 10 ppm VLE; 30 mg/m3 VLE
France - VME: 10 ppm VME; 30 mg/m3 VME
Germany: 10 ppm TWA; 30 mg/m3 TWA
Germany: Skin absorber
Japan: 10 ppm OEL; 30 mg/m3 OEL
Malaysia: 10 ppm TWA; 30 mg/m3 TWA
Netherlands: 5 ppm MAC; 15 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 10 ppm VLA-ED; 30 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Not available.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Always use
a NIOSH or European Standard EN 149 approved
respirator when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: APHA: 15 max
Odor: amine-like
pH: Not available.
Vapor Pressure: 4.9 mbar @ 20 deg C
Viscosity: 0.8 mPas 20 deg C
Boiling Point: 153 deg C @ 760.00mm Hg
Freezing/Melting Point: -61 deg C
Autoignition Temperature: 445 deg C ( 833.00 deg F)
Flash Point: 58 deg C ( 136.40 deg F)
Explosion Limits, lower: 2.20 vol %
Explosion Limits, upper: 16.00 vol %
Decomposition Temperature: >350 deg C
Solubility in water: soluble in water
Specific Gravity/Density: .9450
Molecular Formula: C3H7NO
Molecular Weight: 73.0551
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable.
Conditions to Avoid:
High temperatures, high temperatures, incompatible materials,
ignition sources.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, acids, halogenated agents,
nitrates, chloroformates.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 68-12-2: LQ2100000
LD50/LC50:
CAS# 68-12-2: Inhalation, mouse: LC50 = 9400 mg/m3/2H; Inhalation,
rat: LC50 = 3421 ppm/1H; Inhalation, rat: LC50 = 3421 ppm/3H;
Inhalation, rat: LC50 = 1948 ppm/4H; Oral, mouse: LD50 = 2900 mg/kg;
Oral, rabbit: LD50 = 5 gm/kg; Oral, rat: LD50 = 2800 mg/kg; Skin,
rabbit: LD50 = 4720 mg/kg; Skin, rat: LD50 = >3.2 gm/kg.
Carcinogenicity:
N,N-Dimethylformamide -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Damage to fish: Gold oland test: 18 hrs LC50: 500 mg/l
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: N,N-DIMETHYLFORMAMIDE
Hazard Class: 3
UN Number: 2265
Packing Group: III
IMO
Shipping Name: N,N-DIMETHYLFORMAMIDE
Hazard Class: 3.3
UN Number: 2265
Packing Group: III
RID/ADR
No information available.
USA RQ: CAS# 68-12-2: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 61 May cause harm to the unborn child.
R 20/21 Harmful by inhalation and in contact with
skin.
R 36 Irritating to eyes.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 68-12-2: 1
Canada
CAS# 68-12-2 is listed on Canada's DSL List.
CAS# 68-12-2 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 68-12-2 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 1/16/2002 Revision #1 Date: 12/03/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
2-(3,4-Dimethoxyphenyl)-Ethylamine, 98%
| 120-20-7 |
|
2-Bromo-9-Fluorenone, 95%
| 3096-56-8 |
|
Potassium trihydrogen dioxalate dihydrate, 99%
| 6100-20-5 |
|
2-Chloromethyl-5-(4-Methoxyphenyl)-1,2,4-Oxadiazole, 98%
| 24023-71-0 |
|
2-Chloromethyl-5-(4-Chlorophenyl)-1,2,4-Oxadiazole, 98%
| 24068-15-3 |
|
Tetramethylgermanium, 97%
| 865-52-1 |
|
Phenyltosylate
| 640-60-8 |
|
Tetra-n-butylammonium hexafluorophosphate, 98%
| 3109-63-5 |
|
4-Methyl-2-nitrophenol, 99%
| 119-33-5 |
|
Tetraphenylgermanium, 97%
| 1048-05-1 |
|
2,3-Dibromopropionic Acid, 99%
| 600-05-5 |
|
Magnesium trifluoromethanesulfonate, 98%
| 60871-83-2 |
|
Tetraethyl orthocarbonate, 97%
| 78-09-1 |
|
N-(8-Bromooctyl)phthalimide
| 17702-83-9 |
|
4-Chloro-2-nitrophenol, 98%
| 89-64-5 |
|
cis-N-(4-Chlorobutenyl)Phthalimide, 97%
| 84347-67-1 |
|
4-Fluoro-o-xylene, 98%
| 452-64-2 |
|
2-Phenylglutaric anhydride, 97%
| 2959-96-8 |
|
Methyl tiglate, 98%
| 6622-76-0 |
|
Lobeline sulfate, 99%
| 134-64-5 |
|
Methyl triphenylarsonium iodide, 98%
| 1499-33-8 |
|
Hexa-n-butylditin, 98%
| 813-19-4 |
|
Hydrocortisone, 98%
| 50-23-7 |
|
Benzylurea, 93%
| 538-32-9 |
|
Dichloromethane, peptide synthesis grade, stabilized
| 75-09-2 |
|
N,N-Dicyclohexylcarbodiimide, 0.1M solution in dichloromethane,
| 75-09-2 |
|
N,N'-Dicyclohexylcarbodiimide, 1M solution in N-methylpyrrolidone,
| 538-75-0 |
|
N,N-Dimethylformamide, peptide synthesis grade
| 68-12-2 |
|
1,1,1,3,3,3-Hexafluoro-2-propanol, peptide synthesis grade
| 920-66-1 |
|
alpha,alpha,alpha',alpha',-Tetrachloro-p-xylene
| 7398-82-5 |
|
Bromine Water
| 7726-95-6 |
|
1,1,1,3,3,3-Hexafluoro-2-propanol, 10% in dichloromethane, peptide
| 75-09-2 |
|
1-Methyl-2-pyrrolidone, special automatic peptide synthesizer grade
| 872-50-4 |
|
N-Methylpyrrolidone, peptide synthesis grade
| 872-50-4 |
|
Methylsulfoxide, peptide synthesis grade
| 67-68-5 |
|
Ferrocene, 98%
| 102-54-5 |
|
1,2-Diiodotetrafluoroethane, 98%
| 354-65-4 |
|
5-Chlorothiophene-2-carboxylic acid, 98%
| 24065-33-6 |
|
trans-4-Methoxycinnamaldehyde, 98%
| 24680-50-0 |
|
trans-2-Methyl-2-butenal
| 497-03-0 |
|
Ethyl 3-phenylpropionate, 98%
| 2021-28-5 |
|
Allyl chloroformate, 97%
| 2937-50-0 |
|
2-Amino-3,3-dimethylbutane, 98%
| 3850-30-4 |
|
4-Tert-Butylbenzonitrile, 98%
| 4210-32-6 |
|
3-Aminopropionitrile, stabilized, 98%
| 151-18-8 |
|
4-Chlorophenylsulfonylacetonitrile, 98%
| 1851-09-8 |
|
p-Toluenesulfonylacetonitrile, 98%
| 5697-44-9 |
|
Methyl thiophene-2-carboxylate, 98%
| 5380-42-7 |
|
n-Amylbenzoate, 98%
| 2049-96-9 |
|
Isosorbide, 98%
| 652-67-5 |
|
|