MSDS | : | 1,1,1,3,3,3-Hexafluoro-2-propanol, peptide synthesis grade | CAS | : | 920-66-1 | SYNONYMS | : | HFIP, 1,1,1,3,3,3-Hexafluoroisopropanol |
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**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 920-66-1 |1,1,1,3,3,3-Hexafluoro-2-propanol | | 213-059-4 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: C
Risk Phrases: 20/22 34
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation and if swallowed. Causes burns.
Potential Health Effects
Eye:
Causes eye burns. May cause eye injury.
Skin:
Causes skin burns.
Ingestion:
Harmful if swallowed. Causes gastrointestinal tract burns.
Inhalation:
Harmful if inhaled. May cause irritation of the respiratory tract
with burning pain in the nose and throat, coughing, wheezing,
shortness of breath and pulmonary edema. Causes chemical burns to
the respiratory tract.
Chronic:
Not available.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
soap and water for at least 15 minutes while removing contaminated
clothing and shoes.
Ingestion:
Get medical aid immediately. Do NOT induce vomiting. If conscious
and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air
immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Substance is noncombustible. Vapors mixed with air
can explode when ignited. Vapors may be heavier than air. They can
spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use extinguishing
media most appropriate for the surrounding fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Isolate area and deny entry.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on
skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Keep from contact with oxidizing materials. Corrosives area.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Personal Protective Equipment
Eyes:
Not available.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear a chemical apron.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Clear liquid
Appearance: colourless
Odor: characteristic odor
pH: Not available.
Vapor Pressure: 269 mbar @ 30 deg C
Viscosity: 1.65 mPas 20 deg C
Boiling Point: 59 deg C @ 760 mmHg
Freezing/Melting Point: -4 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 1000 g/l water (25C)
Specific Gravity/Density: 1.62
Molecular Formula: C3H2F6O
Molecular Weight: 168.04
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, strong acids, strong bases, acid chlorides, alkali
metals, aluminum, zinc.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen fluoride, fluorine.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 920-66-1: UB6450000
LD50/LC50:
CAS# 920-66-1: Inhalation, rat: LC50 = 1974 ppm/4H; Oral, mouse:
LD50 = 600 mg/kg.
Carcinogenicity:
1,1,1,3,3,3-Hexafluoro-2-propanol -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
No information available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.*
Hazard Class: 8
UN Number: 3265
Packing Group: II
IMO
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing Group: II
RID/ADR
No information available.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 20/22 Harmful by inhalation and if swallowed.
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 920-66-1: No information available.
United Kingdom Occupational Exposure Limits
Canada
CAS# 920-66-1 is listed on Canada's DSL List.
CAS# 920-66-1 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 920-66-1 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 1/16/2002 Revision #0 Date: Original.
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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| 60871-83-2 |
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| 78-09-1 |
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| 89-64-5 |
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cis-N-(4-Chlorobutenyl)Phthalimide, 97%
| 84347-67-1 |
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4-Fluoro-o-xylene, 98%
| 452-64-2 |
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2-Phenylglutaric anhydride, 97%
| 2959-96-8 |
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| 6622-76-0 |
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| 134-64-5 |
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| 1499-33-8 |
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| 813-19-4 |
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| 50-23-7 |
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| 538-32-9 |
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Dichloromethane, peptide synthesis grade, stabilized
| 75-09-2 |
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| 75-09-2 |
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| 75-09-2 |
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| 872-50-4 |
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| 872-50-4 |
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Methylsulfoxide, peptide synthesis grade
| 67-68-5 |
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| 102-54-5 |
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| 354-65-4 |
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| 24065-33-6 |
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trans-4-Methoxycinnamaldehyde, 98%
| 24680-50-0 |
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trans-2-Methyl-2-butenal
| 497-03-0 |
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| 2021-28-5 |
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| 2937-50-0 |
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| 3850-30-4 |
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4-Tert-Butylbenzonitrile, 98%
| 4210-32-6 |
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| 151-18-8 |
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4-Chlorophenylsulfonylacetonitrile, 98%
| 1851-09-8 |
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| 5697-44-9 |
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| 5380-42-7 |
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| 2049-96-9 |
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