**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 62-53-3 |Aniline | 99 | 200-539-3 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T N
Risk Phrases: 20/21/22 40 50 48/23/24/25
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect. Very toxic to aquatic
organisms. Toxic : danger of serious damage to health by prolonged
exposure through inhalation, contact with skin and if
swallowed.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Causes severe eye irritation. May cause lacrimation (tearing),
blurred vision, and photophobia. May cause chemical conjunctivitis
and corneal damage.
Skin:
Causes skin irritation. Harmful if absorbed through the skin. May
cause skin sensitization, an allergic reaction, which becomes
evident upon re-exposure to this material. Vapors are readily
absorbed through the skin.
Ingestion:
Harmful if swallowed. Aniline acts through an intermediate to change
hemoglobin to methemoglobin. In one subject, 65 mg of aniline
increased the methemoglobin level by 16% within 2 hours. Intense
methemoglobinemia may lead to asphyxia severe enough to injure the
cells of the central nervous system. Pathologic findings in acute
fatalities from aniline include chocolate color of the blood; injury
to the kidney, liver and spleen; and hemolysis.
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation.
Methemoglobinemia is characterized by dizziness, drowsiness,
headache, shortness of breath, cyanosis (bluish discoloration of
skin due to deficient oxygenation of the blood), rapid heart rate and
chocolate-brown blood. Inhalation of aniline causes anoxia due to the
formation of methemoglobin.
Chronic:
May cause liver and kidney damage. Repeated exposure may cause
sensitization dermatitis. Chronic exposure may cause hemolysis of the
red blood cells followed by stimulation of the bone marrow. May cause
cyanosis - a blue-gray coloring of the skin and lips caused by a lack
of oxygen. Animal studies have reported the development of tumors.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive
measures: bed rest and oxygen inhalation. Cleansing of the entire
contaminated area of the body is of utmost importance. Do not
administer alcohol in any form. Individuals with liver or kidney
disorders, impaired cardiovascular status, or a history of
alcoholism may be more susceptible to the effects of this product.
Effects may be delayed. If cyanosis is severe, intravenous injection
of Methylene Blue, 1mg/kg of body weight may be of value.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Water runoff can cause environmental damage. Dike
and collect water used to fight fire. During a fire, irritating and
highly toxic gases may be generated by thermal decomposition or
combustion. Use water spray to keep fire-exposed containers cool.
Combustible liquid and vapor.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Provide ventilation. Approach spill from upwind. Control runoff and
isolate discharged material for proper disposal. Use water spray to
cool and disperse vapors and protect personnel.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Keep container tightly closed. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to
heat, sparks or open flames. Use only with adequate ventilation. Keep
away from heat and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed
container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances.
Poison room locked. Keep away from acids. Material darkens in color
on storage. Store protected from moisture. Store protected from
light.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 62-53-3:
United Kingdom, WEL - TWA: 1 ppm TWA; 4 mg/m3 TWA
United Kingdom, WEL - STEL: 3 ppm STEL; 12 mg/m3 STEL
United States OSHA: 5 ppm TWA; 19 mg/m3 TWA
Belgium - TWA: 2 ppm VLE; 7.7 mg/m3 VLE
France - VME: 2 ppm VME; 10 mg/m3 VME
Germany: 2 ppm TWA; 7.7 mg/m3 TWA
Germany: Skin absorber
Japan: 1 ppm OEL; 3.8 mg/m3 OEL
Malaysia: 2 ppm TWA; 7.6 mg/m3 TWA
Netherlands: 0.25 ppm MAC; 1 mg/m3 MAC
Russia: 0.1 mg/m3 TWA
Spain: 2 ppm VLA-ED; 7.7 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: oily - colorless to brown
Odor: amine-like - characteristic odor
pH: 8.1 (0.2M soln)
Vapor Pressure: 0.49 mm Hg @ 25 deg C
Viscosity: 4.435 cp @ 20 deg C
Boiling Point: 184 deg C @ 760 mmHg
Freezing/Melting Point: -6 deg C
Autoignition Temperature: 615 deg C ( 1,139.00 deg F)
Flash Point: 70 deg C ( 158.00 deg F)
Explosion Limits, lower: 1.3 vol %
Explosion Limits, upper: 11 vol %
Decomposition Temperature:
Solubility in water: Slightly soluble.
Specific Gravity/Density: 1.0217 @ 20C
Molecular Formula: C6H7N
Molecular Weight: 93.13
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. May discolor on
exposure to air and light.
Conditions to Avoid:
Light, ignition sources, excess heat, exposure to moist air or water,
prolonged exposure to air, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, hexachloromelamine,
trichloromelamine.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 62-53-3: BW6650000
LD50/LC50:
CAS# 62-53-3: Dermal, guinea pig: LD50 = 1290 mg/kg; Draize test,
rabbit, eye: 102 mg Severe; Draize test, rabbit, eye: 20 mg/24H
Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation,
mouse: LC50 = 175 ppm/7H; Oral, mouse: LD50 = 464 mg/kg; Oral, rat:
LD50 = 250 mg/kg; Skin, rabbit: LD50 = 820 uL/kg; Skin, rat: LD50 =
1400 mg/kg.
Carcinogenicity:
Aniline -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 1/1/90
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 425-488 mg/L; 5,15 min;
Microtox test at 14.9-15.1CWater flea Daphnia: LC50 = 0.10 mg/L; 48
Hr; UnspecifiedFish: Rainbow trout: LC50 = 8.2 mg/L; Max. exposure =
7 days; UnspecifiedFish: Bluegill/Sunfish: 1020 ppm; 1 Hr;
Unspecified
Other
Dangerous to aquatic life in high concentrations.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing Group: II
IMO
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing Group: II
RID/ADR
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing group: II
USA RQ: CAS# 62-53-3: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 40 Limited evidence of a carcinogenic effect.
R 48/23/24/25 Toxic : danger of serious damage to
health by prolonged exposure through inhalation,
contact with skin and if swallowed.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 62-53-3: 2
Canada
CAS# 62-53-3 is listed on Canada's DSL List.
CAS# 62-53-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 62-53-3 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 6/04/1999 Revision #5 Date: 12/19/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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