**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 67-66-3 |Chloroform | 48 | 200-663-8 |
|----------------|--------------------------------------|----------|-----------|
| 108-95-2 |Phenol | 50 | 203-632-7 |
|----------------|--------------------------------------|----------|-----------|
| 123-51-3 |Isoamyl alcohol | 2 | 204-633-5 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: T C
Risk Phrases: 23/24/25 34 40 48/20/21/22
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Causes
burns. Limited evidence of a carcinogenic effect. Harmful : danger of
serious damage to health by prolonged exposure through inhalation, in
contact with skin and if swallowed.Light sensitive.Mutagen.
Potential Health Effects
Eye:
Causes eye burns. Causes redness and pain.
Skin:
May be fatal if absorbed through the skin. Causes skin burns. Phenol
solutions may be absorbed through the skin rapidly to produce
systemic poisoning and possible death.
Ingestion:
May be fatal if swallowed. Causes gastrointestinal tract burns. May
cause liver damage. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness,
drowsiness, and nausea. Advanced stages may cause collapse,
unconsciousness, coma and possible death due to respiratory failure.
May cause cardiac disturbances. Aspiration of material into the lungs
may cause chemical pneumonitis, which may be fatal. Possible
aspiration hazard. May cause hallucinations and distorted
perceptions.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. May be fatal if exposed to high concentrations. May cause
cardiac sensitization and possible failure. Causes chemical burns to
the respiratory tract. Inhalation of large amounts may cause
respiratory stimulation, followed by respiratory depression,
convulsions and possible death due to respiratory paralysis. May be
absorbed through the lungs.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause defatting and
dermatitis. May cause reproductive and fetal effects. Effects may be
delayed. Laboratory experiments have resulted in mutagenic effects.
Repeated skin contact may cause dermatitis with dark pigmentation of
the skin. Toxicity may be increased by exposure to alcohol,
steroids, and ketones. Prolonged exposure may cause liver, kidney,
and heart damage.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Causes cardiac sensitization to endogenous catelcholamines which may
lead to cardiac arrhythmias. Do NOT use adrenergic agents such as
epinephrine or pseudoepinephrine. Persons with liver, kidney, or
central nervous system diseases may be at increased risk from
exposure to this product. Alcoholic beverage consumption may enhance
the toxic effects of this substance. Effects may be delayed.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Will burn
if involved in a fire. Use water spray to keep fire-exposed
containers cool. Vapors may be heavier than air. They can spread
along the ground and collect in low or confined areas. Containers may
explode when heated. Approach fire from upwind to avoid hazardous
vapors and toxic decomposition products.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water spray,
dry chemical, carbon dioxide, or chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation. Approach spill from upwind.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Do
not breathe dust, vapor, mist, or gas. Do not ingest or inhale.
Store protected from light. Use only in a chemical fume hood.
Storage:
Do not store in direct sunlight. Keep refrigerated. (Store below
4C/39F.) Keep away from acids. Do not store near alkaline
substances. Separate from strong mineral acids.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 67-66-3:
United Kingdom, WEL - TWA: 2 ppm TWA; 9.9 mg/m3 TWA
United Kingdom, WEL - STEL: 6 ppm STEL; 29.7 mg/m3 STEL
United States OSHA: ; 50 ppm Ceiling; 240 mg/m3 Ceiling
Belgium - TWA: 10 ppm VLE; 50 mg/m3 VLE
France - VME: 5 ppm VME; 25 mg/m3 VME
France - VLE: 50 ppm VLE; 250 mg/m3 VLE
Germany: 4 ppm TWA (large technical manufacture and use); 20 mg/m
TWA (large technical m
Germany: Skin absorber
Japan: 10 ppm OEL; 49 mg/m3 OEL
Malaysia: 10 ppm TWA; 49 mg/m3 TWA
Netherlands: 5 ppm STEL; 25 mg/m3 STEL
Netherlands: 1 ppm MAC; 5 mg/m3 MAC
Spain: 2 ppm VLA-ED; 10 mg/m3 VLA-ED
CAS# 108-95-2:
United Kingdom, WEL - TWA: 2 ppm TWA
United Kingdom, WEL - STEL: 6 ppm STEL
United States OSHA: 5 ppm TWA; 19 mg/m3 TWA
Belgium - TWA: 2 ppm VLE; 7.8 mg/m3 VLE
France - VME: 5 ppm VME; 19 mg/m3 VME
Germany: 5 ppm TWA; 19 mg/m3 TWA
Germany: Skin absorber
Japan: 5 ppm OEL; 19 mg/m3 OEL
Malaysia: 5 ppm TWA; 15 mg/m3 TWA
Netherlands: 2 ppm MAC; 8 mg/m3 MAC
Russia: 0.3 mg/m3 TWA
Spain: 2 ppm VLA-ED; 8 mg/m3 VLA-ED
CAS# 123-51-3:
United Kingdom, WEL - TWA: 100 ppm TWA; 366 mg/m3 TWA
United Kingdom, WEL - STEL: 125 ppm STEL; 458 mg/m3 STEL
United States OSHA: 100 ppm TWA; 360 mg/m3 TWA
Belgium - TWA: 100 ppm VLE; 366 mg/m3 VLE
Belgium - STEL: 125 ppm VLE; 459 mg/m3 VLE
France - VME: 100 ppm VME; 360 mg/m3 VME
Germany: 100 ppm TWA; 370 mg/m3 TWA
Japan: 100 ppm OEL; 360 mg/m3 OEL
Malaysia: 100 ppm TWA; 361 mg/m3 TWA
Netherlands: 100 ppm MAC; 360 mg/m3 MAC
Russia: 5 mg/m3 TWA
Spain: 100 ppm VLA-ED; 366 mg/m3 VLA-ED
Spain: 125 ppm VLA-EC; 458 mg/m3 VLA-EC
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: Clear yellow solution
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Air sensitive. Light sensitive.
Conditions to Avoid:
High temperatures, light, exposure to air.
Incompatibilities with Other Materials:
Alkali metals, fluorine, caustics (e.g. ammonia, ammonium hydroxide,
calcium hydroxide, potassium hydroxide, sodium hydroxide),
dinitrogen tetraoxide, sodium hydroxide + methanol, potassium
tert-butoxide, chemically active metals, powdered aluminum, nitrogen
tetroxide, powdered magnesium, acetone + alkali, disilane,
perchloric acid + phosphorus pentoxide, sodium methylate,
triisopropylphosphine.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, chlorine,
phosgene gas.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 67-66-3: FS9100000
CAS# 108-95-2: SJ3325000
CAS# 123-51-3: EL5425000
LD50/LC50:
CAS# 67-66-3: Draize test, rabbit, eye: 148 mg; Draize test, rabbit,
eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 17200 mg/m3/2H; Inhalation, mouse: LC50 =
6000 mg/m3/6H; Inhalation, rat: LC50 = 47702 mg/m3/4H; Inhalation,
rat: LC50 = 6000 mg/m3/6H; Oral, mouse: LD50 = 36 mg/kg; Oral, rat:
LD50 = 695 mg/kg; Oral, rat: LD50 = 1250 mg/kg; Skin, rabbit: LD50 =
>20 gm/kg.
CAS# 108-95-2: Draize test, rabbit, eye: 5 mg Severe; Draize test,
rabbit, skin: 500 mg/24H Severe; Draize test, rabbit, skin: 100 mg
Mild; Inhalation, mouse: LC50 = 177 mg/m3; Inhalation, mouse: LC50 =
177 mg/m3/4H; Inhalation, rat: LC50 = 316 mg/m3; Inhalation, rat:
LC50 = 316 mg/m3/4H; Oral, mouse: LD50 = 270 mg/kg; Oral, rat: LD50 =
317 mg/kg; Oral, rat: LD50 = 512 mg/kg; Skin, rabbit: LD50 = 630
mg/kg; Skin, rat: LD50 = 669 mg/kg; Skin, rat: LD50 = 1500 mg/kg.
CAS# 123-51-3: Draize test, rabbit, eye: 20 mg/24H Moderate; Draize
test, rabbit, skin: 20 mg/24H Moderate; Oral, rabbit: LD50 = 3438
mg/kg; Oral, rat: LD50 = 1300 mg/kg; Oral, rat: LD50 = 4300 mg/kg;
Skin, rabbit: LD50 = 3970 uL/kg.
Carcinogenicity:
Chloroform -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 10/1/87
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Phenol -
Not listed by ACGIH, IARC, or NTP.
Isoamyl alcohol -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Channel catfish: LC50 = 75 ppm; 96 Hr; UnspecifiedFish: Rainbow
trout: LC50 = 43.8 mg/L; 96 Hr; Static bioassayFish: Fathead Minnow:
LC50 = 129.0 mg/L; 96 Hr; Static bioassay (pH = 7.6-8.3)Fish:
Bluegill/Sunfish: LC50 = 100.0 mg/L; 96 Hr; Static bioassayWater
flea Daphnia: EC50 = 28.9 mg/L; 48 Hr; Static bioassayThe majority of
the environmental releases from industrial uses are to the
atmosphere; releases to water and land will be primarily lost by
evaporation and will end up in the atmosphere. Release to the
atmosphere may be transported long distances and will photodegrade
with a half-life of a
few months. Spills and other releases on land
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: Not reviewed.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not reviewed.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not reviewed.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 67-66-3: 10 lb final RQ; 4.54 kg final RQ
USA RQ: CAS# 108-95-2: 1000 lb final RQ; 454 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T C
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 34 Causes burns.
R 40 Limited evidence of a carcinogenic effect.
R 48/20/21/22 Harmful : danger of serious damage to
health by prolonged exposure through inhalation, in
contact with skin and if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 67-66-3: 3
CAS# 108-95-2: 2
CAS# 123-51-3: 1
Canada
CAS# 67-66-3 is listed on Canada's DSL List.
CAS# 108-95-2 is listed on Canada's DSL List.
CAS# 123-51-3 is listed on Canada's DSL List.
CAS# 67-66-3 is listed on Canada's Ingredient Disclosure List.
CAS# 108-95-2 is listed on Canada's Ingredient Disclosure List.
CAS# 123-51-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-66-3 is listed on the TSCA inventory.
CAS# 108-95-2 is listed on the TSCA inventory.
CAS# 123-51-3 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
R 34 Causes burns.
R 24/25 Toxic in contact with skin and if swallowed.
MSDS Creation Date: 11/19/2004 Revision #1 Date: 11/19/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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