**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 68-12-2 |N,N-Dimethylformamide | 99 | 200-679-5 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 20/21 36 61
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation and in contact with skin. Irritating to eyes.
May cause harm to the unborn child.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause kidney damage. May cause liver damage.
Inhalation:
Causes respiratory tract irritation. Vapors may cause dizziness or
suffocation.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause dermatitis. May cause
reproductive and fetal effects.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting
unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a
fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Will burn if involved in a fire. Use
water spray to keep fire-exposed containers cool. Containers may
explode in the heat of a fire. Flammable liquid and vapor. Vapors
may be heavier than air. They can spread along the ground and
collect in low or confined areas. Containers may explode when heated.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. Use water spray to cool fire-exposed
containers. Water may be ineffective. Use agent most appropriate to
extinguish fire. Do NOT use straight streams of water.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Do not flush into a sewer. Clean
up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Use a spark-proof
tool. Provide ventilation. A vapor suppressing foam may be used to
reduce vapors.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Ground and bond containers when
transferring material. Use spark-proof tools and explosion proof
equipment. Avoid contact with eyes, skin, and clothing. Do not
breathe dust, vapor, mist, or gas. Empty containers retain product
residue, (liquid and/or vapor), and can be dangerous. Keep container
tightly closed. Keep away from heat, sparks and flame. Avoid
ingestion and inhalation. Do not ingest or inhale. Use with adequate
ventilation. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
Flammables-area.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 68-12-2:
United Kingdom, OES - TWA: 10 ppm TWA; 30 mg/m3 TWA
United Kingdom, OES - STEL: 20 ppm STEL; 61 mg/m3 STEL
United States OSHA: 10 ppm TWA; 30 mg/m3 TWA
Belgium - TWA: 10 ppm VLE; 30 mg/m3 VLE
France - VME: 10 ppm VME; 30 mg/m3 VME
Germany: 10 ppm TWA; 30 mg/m3 TWA
Germany: Skin absorber
Japan: 10 ppm OEL; 30 mg/m3 OEL
Malaysia: 10 ppm TWA; 30 mg/m3 TWA
Netherlands: 5 ppm MAC; 15 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 10 ppm VLA-ED; 30 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: clear, colorless
Odor: Faint, amine odor.
pH: 6 - 8 @ 20% aq.sol.
Vapor Pressure: 4.9 mbar @ 20 C
Viscosity: 0.8 mPas @ 20 C
Boiling Point: 153 deg C
Freezing/Melting Point: 61 deg C
Autoignition Temperature: 445 deg C ( 833.00 deg F)
Flash Point: 57 deg C ( 134.60 deg F)
Explosion Limits, lower: 2.2
Explosion Limits, upper: 15.2
Decomposition Temperature: Not available.
Solubility in water: Completely soluble in water.
Specific Gravity/Density: 0.9450
Molecular Formula: C3H7NO
Molecular Weight: 73.0551
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Mechanical shock, incompatible materials, ignition sources, excess
heat, temperatures above 55C.
Incompatibilities with Other Materials:
Oxidizing materials, ammonia, anhydrides, iron, nitrates, phenols,
isocyanates, acids (mineral, non-oxidizing, e.g. hydrochloric acid,
hydrofluoric acid, muriatic acid, phosphoric acid), acids (mineral,
oxidizing, e.g. chromic acid, hypochlorous acid, nitric acid,
sulfuric acid), metals (alkali and alkaline, e.g. cesium, potassium,
sodium), metals and metal compounds (toxic, e.g. beryllium, lead
acetate, nickel carbonyl, tetraethyl lead), oxidizing agents
(strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium
nitrate), reducing agents (strong, e.g. aluminum carbide,
chlorosilane, hydrogen phosphide, lithium hydride), water reactive
substances (e.g. acetic anyhdride, alkyl aluminum chloride, calcium
carbide, ethyl dichlorosilane), carbontetrachloride, chlorinated
hydrocarbons, violent reaction with halogens, organic materials.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 68-12-2: LQ2100000
LD50/LC50:
CAS# 68-12-2: Inhalation, mouse: LC50 = 9400 mg/m3/2H; Inhalation,
rat: LC50 = 3421 ppm/1H; Inhalation, rat: LC50 = 3421 ppm/3H;
Inhalation, rat: LC50 = 1948 ppm/4H; Oral, mouse: LD50 = 2900 mg/kg;
Oral, rabbit: LD50 = 5 gm/kg; Oral, rat: LD50 = 2800 mg/kg; Skin,
rabbit: LD50 = 4720 mg/kg; Skin, rat: LD50 = >3.2 gm/kg.
Carcinogenicity:
N,N-Dimethylformamide -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: N,N-DIMETHYLFORMAMIDE
Hazard Class: 3
UN Number: 2265
Packing Group: III
IMO
Shipping Name: N,N-DIMETHYLFORMAMIDE
Hazard Class: 3.3
UN Number: 2265
Packing Group: III
RID/ADR
Shipping Name: N,N-DIMETHYLFORMAMIDE
Hazard Class: 3
UN Number: 2265
Packing group: III
USA RQ: CAS# 68-12-2: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 61 May cause harm to the unborn child.
R 20/21 Harmful by inhalation and in contact with
skin.
R 36 Irritating to eyes.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 68-12-2: 1
Canada
CAS# 68-12-2 is listed on Canada's DSL List.
CAS# 68-12-2 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 68-12-2 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 11/06/2001 Revision #3 Date: 12/03/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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