NATIONAL INSTITUTE OF STANDARD -- CHROMIUM OXIDE
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Material Safety Data Sheet
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MSDS Num: CJGSQ
MSDS NAME: CHROMIUM OXIDE
Responsible Party
Name: NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY
Address: 100 BUREAU DR
City: GAITHERSBURG MD 20899
Info Phone: 301-975-2019;301-975-6439
Emergency Phone Number: 301-975-2019;301-975-6439
Proprietary Ind: Y
Review Ind: Y
Published: Y
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Contractor Summary
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Name: NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY
Address: 100 BUREAU DR
City: GAITHERSBURG MD 20899
Phone: 301-975-2019;301-975-6439
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Item Description Information
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Specification Number: NOT HAZ BY DOT REGS
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Ingredients
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Name: *** PROPRIETARY ***
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Health Hazards Data
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Route Of Entry Inds - Inhalation: YES
Skin: YES
Ingestion: YES
Carcinogenicity Inds - NTP: YES
IARC: YES
OSHA: NO
Effects of Exposure: INHALATION OF CHROMIUM OXIDE MAY CAUSE IRRITATION,
COUGHING AND CHEST DISCOMFORT. INTRATRACHEAL ADMINISTRATION INDUCED AN
INCREASED INCIDENCE OF SARCOMAS, TUMORS, AND RETICULUM CELL SARCOMAS OF THE L
UNG IN RATS. ANIMAL STUDIES INDICATE ABSORPTION OF TRIVALENT CHROMIUM
COMPOUNDS FROM THE LUNGS IS SLOW FOLLOWING INTRATRACHEAL ADMINISTRATION.
ALLERGIC REACTIONS MAY OCCUR IN PREVIOUSLY EXPOSED PERSON S. REPEATED OR
PROLONGED EXPOSURE MAY LEAD TO SENSITIZATION. PNEUMOCONIOSIS HAS BEEN
REPORTED. IRRITATION OF THE BRONCHUS AND LUNG PARENCHYMA. DYSTROPHIC (A
DISORDER CAUSED BY FAULTY NUTRITION) (EFTS OF OVEREXP)
Explanation Of Carcinogenicity: CHROMIUM OXIDE: NTP 8TH ANNUAL REPORT ON
CARCINOGENS 1998: KNOWN TO BE HUMAN CARCINOGEN. IARC GROUP 1, VOL 49, P 214,
1990.
Signs And Symptions Of Overexposure: HLTH HAZ: CHANGES IN LIVER & KIDNEYS,
& PULMONARY ADENOMAS (A BENIGN TUMOR OF A GRANULAR STRUCTURE/OF GRANULAR
ORIGIN LOCATED IN LUNG) HAVE REPORTED TO OCCUR IN ANIMALS. ADVERSE EFTS ON
MACROPHAGES WE RE REPORTED IN RABBITS EXPOSED FOR 4-6 WEEKS. SKIN &/EYE
CONTACT W/TRIVALENT CHROMIUM COMPOUNDS MAY CAUSE IRRIT. REPEATED CONTACT
W/SKIN MAY CAUSE DERM (INFLAMM OF SKIN) & SENSIT. INGEST OF TRIVALENT
CHROMIUM CMPDS MAY CAUSE GI IRRIT. INCREASED INCIDENCE OF MAMMARY
FIBROADENOMAS WAS REPORTED IN RATS WHEN ADMIN IN DIET. TRIVALENT CHROMIUM
COMPOUNDS MAY CROSS PLACENTA. TARGET ORGAN(S) OF ATTACK: POI SONING MAY
AFFECT RESPIRATORY SYSTEM.
First Aid: SKIN: REMOVE CONTAMD SHOES & CLOTHING. RINSE AFFECTED AREA W/LRG
AMNS OF H*2O FOLLOW ED BY WASHING AREA W/SOAP & H*2O. CONTACT MED
ASSISTANCE IF NECESSARY. EYE: IMMED FLUSH EYES, INCLUDING UNDER EYELI DS,
W/COPIOUS AMTS OF H*2O FOR AT LEAST 15 MIN. CONTACT MED ASSISTANCE IF NEC.
INHAL: REMOVE VICTIM TO FRESH AIR. IF BREATHING IS DIFFICULT, GIVE OXYGEN; IF
VICTIM IS NOT BREATHING, GIVE ARTF RESP APP RVD BY NIOSH. CONTACT MED
ASSISTANCE IF NEC. INGEST: WASH OUT MOUTH W/H*2O. CONTACT MED ASSISTANCE IF
NEC. NOTE TO MD: FOLLOWING ANTIDOTE HAS BEEN SUGGESTED. HOWEVER, DECISION AS
TO WHETHER SEVERITY O F POISONING (SUPDAT)
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Handling and Disposal
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Spill Release Procedures: NOTIFY SAFETY PERSONNEL OF MAJOR SPILLS AND/OR LEAKS.
EVACUATE ALL NONESSENTIAL PERSONNEL. AVOID RAISING DUST. RECOVER SMALL SPILLS
WITH A CLEAN SHOVEL, AND PLACE INTO A CLEAN, DRY CONTAINER FOR LATER
DISPOSAL. REMAINING RESIDUE SHOULD BE CLEANED UP USING A HIGH EFFICIENCY
PARTICULATE FILTER.
Waste Disposal Methods: FOLLOW ALL FEDERAL, STATE AND LOCAL REGULATIONS.
Handling And Storage Precautions: STORE MATERIAL IN A COOL, DRY, WELL
VENTILATED AREA AND PROTECT CONTAINERS FROM PHYSICAL DAMAGE.
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Fire and Explosion Hazard Information
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Extinguishing Media: THIS MATERIAL IS NONCOMBUSTIBLE. USE EXTINGUISHING MEDIA
THAT IS APPROPRIATE TO THE SURROUNDING FIRE.
Fire Fighting Procedures: WEAR NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT (FP N).
Unusual Fire/Explosion Hazard: NO UNUSUAL FIRE/EXPLOSION HAZ ARE ASSOCIATED
W/THIS MATL. HOWEVER, CERIUM OXIDE WILL PRESENT AN IGNITION &/EXPLOSION
HAZ W/FOLLOWING MATLS: IGNIT RXN: CHLORINE TRIFLUORIDE (VIOLENT RXN
W/POSSIBLE IGNI T) COPPER CHROMATE (POSSIBLE IGNIT RXN). EXPLOSION RXN:
GLYCEROL (POSS IGNITION RXN) NITROALKANES (POSS EXPLOSION RXN).
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Control Measures
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Respiratory Protection: PERSONS HANDLING THIS MATL SHOULD WEAR AN
AIR-PURIFYING RESP W/ HIGH-EFFICIENCY PARTICULATE FILTER. SPECIFIC RESP
SELECTED MUST BE BASED ON CONTAMINATION LEVELS FOUND IN WORKPLACE, MUST BE
BASED ON SPECIFIC OPERATION, MUST NOT EXCEED WORKING LIMITS OF RESPIRATOR
& MUST BE APPROVED BY NIOSH.
Protective Gloves: IMPERVIOUS GLOVES (FP N).
Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES (FP N).
Other Protective Equipment: ANSI APPRVD EMERGENCY EYEWASH & DELUGE SHOWER (FP
N). LAB COATS. NOTE: CONTACT LENSES POSE A SPECIAL PROBLEM; SOFT LENSES MAY
ABSORB IRRITANTS & ALL LENSES CONC THEM. DO NOT WEAR CONTACT LENSES IN LAB.
Supplemental Safety and Health: FIRST AID PROC: REQUIRES ADMIN OF ANY ANTIDOTE
& THE ACTUAL DOSE REQD SHOULD BE MADE BY QUALIFIED PERS. ANTIDOTE SHOULD
BE ADMIN BY QUALIFIED MED PERS. CHROMIUM POISONING: USE OF DIMERCAPROL HAS
BEEN SUGGESTED ON BASIS OF FINDINGS IN ANIMALS. GIVE 3 MG/KG (OR 0.3 ML/10
KG) EVER 4 HRS, (OTHER INFORMATION)
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Physical/Chemical Properties
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Boiling Point: =3000.C, 5432.F
Melt/Freeze Pt: =2435.C, ######F
Vapor Density: 5.21
Solubility in Water: PRACTICALLY INSOLUBLE
Appearance and Odor: ODORLESS, LIGHT TO DARK GREEN HEXAGONAL CRYSTALS.
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: AVOID EXCESSIVE TEMPERATURES. CHROMIC OXIDE TURNS
BROWN ON HEATING BUT WILL REVERT BACK TO ITS GREEN COLOR UPON COOLING.
Materials To Avoid: CHROMIC OXIDE IS INCOMPATIBLE WITH OXIDIZERS. IT WILL FORM
AN EXOTHERMIC REACTION W/RUBIDIUM ACETYLIDE & A VIOLENT EXOTHERMIC REACTION
W/LITHIUM AT 180C. A VIGOROUS REACTION IS FORMED WITH OXYGEN DIFLUORIDE &
CHROMIC OXIDE.
Hazardous Decomposition Products: THERMAL DECOMPOSITION MAY RELEASE TOXIC
AND/OR HAZARDOUS GASES.
Hazardous Polymerization Indicator: NO
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Toxicological Information
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Ecological Information
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MSDS Transport Information
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Transport Information: DOT CLASSIFICATION: NOT HAZARDOUS BY DOT REGULATIONS.
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Regulatory Information
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Other Information
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Other Information: SUPDAT: INTRAMUSCULARLY FOR THE FIRST 2 DAYS AND THEN 2
MG/KG EVERY 12 HOURS FOR A TOTAL OF 10 DAYS. MOLECULAR WEIGHT: 151.99
DENSITY: 5.21 SOLUBILITY IN OTHER COMPOUNDS: SLIGHT SOLUBLE IN ACIDS AND
ALKALIES. INSOLUBLE IN ALCOHOL AND ACETONE.
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HAZCOM Label
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MSDS NAME: CHROMIUM OXIDE
Company: NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY
Street: 100 BUREAU DR
City: GAITHERSBURG MD
Zipcode: 20899
Health Emergency Phone: 301-975-2019;301-975-6439
Label Required IND: Y
Date Of Label Review: 06/24/1999
Status Code: A
Label Date: 03/26/1999
Origination Code: F
Chronic Hazard IND: Y
Eye Protection IND: YES
Skin Protection IND: YES
Signal Word: WARNING
Respiratory Protection IND: YES
Health Hazard: Moderate
Contact Hazard: Moderate
Fire Hazard: None
Reactivity Hazard: None
Hazard And Precautions: ACUTE: INHAL: IRRITATION, COUGHING AND CHEST
DISCOMFORT. ALLERGIC REACTIONS MAY OCCUR IN PREVIOUSLY EXPOSED PERSONS. MAY
LEAD TO SENSITIZATION. PNEUMOCONIOSIS, IRRITATION OF BRONCHUS AND LUNG PAR
ENCHYMA, DYSTROPHIC, CHANGES IN LIVER AND KIDNEYS, PULMONARY ADENOMAS.
ADVERSE EFTS ON MACROPHAGES. SKIN & EYE: IRRITATION. SKIN DERM AND
SENSITIZATION. INGEST: GI IRRITATION. CHRONIC: CANCER H AZARD. CONTAINS
MATERIAL LISTED AS HUMAN LUNG CARCINOGEN (FP N). MAMMARY FIBROADENOMAS.
TRIVALENT CHROMIUM COMPOUNDS MAY CROSS THE PLACENTA.
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Disclaimer (provided with this information by the compiling agencies): This
information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
viability by or to any person or persons outside the Department of Defense
nor any person or persons contracting with any instrumentality of the United
States of America and disclaims all liability for such use. Any person
utilizing this instruction who is not a military or civilian employee of the
United States of America should seek competent professional advice to verify
and assume responsibility for the suitability of this information to their
particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.
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