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MSDS Material Safety Data Sheet
CAS

9076-44-2

File Name: agrippina_bcs_deakin_edu_au---Chymostatin.asp
                              SIGMA-ALDRICH

Material Safety Data Sheet

Date Printed: 17/MAY/2005
Date Updated: 14/MAR/2004
Version 1.1
According to 91/155/EEC


1 - Product and Company Information

Product Name CHYMOSTATIN
Product Number C7268

Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566

2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
CHYMOSTATIN 9076-44-2 None None

Synonyms N-脻-Nalpha-Carbonyl-Cpd-X-Phe-al篓-Phe

3 - Hazards Identification


SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Not hazardous according to Directive 67/548/EC.

4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

5 - Fire Fighting Measures

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.

STORAGE
Conditions of Storage: Keep tightly closed.
Store at -20掳C

SPECIAL REQUIREMENTS: Moisture sensitive.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Mechanical exhaust required.

GENERAL HYGIENE MEASURES
Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.

9 - Physical and Chemical Properties

Appearance Physical State: Solid
Color: Faintly beige

Property Value At Temperature or Pressure

pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A


SIGMA - C7268 www.sigma-aldrich.com Page 2
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Materials to Avoid: Strong acids, Strong bases.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

RTECS NUMBER: GC3047700

ACUTE TOXICITY

LD50
Intraperitoneal
Mouse
>500 MG/KG

ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.

CONDITIONS AGGRAVATED BY EXPOSURE
A protease inhibitor. The toxicological properties have not been
thoroughly investigated.

12 - Ecological Information

No data available.

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose


SIGMA - C7268 www.sigma-aldrich.com Page 3
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

14 - Transport Information

RID/ADR
Non-hazardous for road transport.

IMDG
Non-hazardous for sea transport.

IATA
Non-hazardous for air transport.

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
S-PHRASES: 22 24/25
Do not breathe dust. Avoid contact with skin and eyes.

Not hazardous according to Directive 67/548/EC.

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIMER
For R&D use only. Not for drug, household or other uses.




SIGMA - C7268 www.sigma-aldrich.com Page 4

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