Material Safety Data Sheet
Material Name: Pronto!鈩? Short Oligo Hybridization Solution ID: C-314
S E C T I O N 1 . C H E M I C A L P R O D U C T A N D CO M PA N Y I D E N T I F I C AT I O N
Product Name:
Pronto!鈩? Short Oligo Hybridization Solution
Manufacturer Information
Corning Incorporated
Life Sciences Phone: (800) 492-1110
45 Nagog Park Emergency # CHEMTREC: (800) 424-9300
Acton, MA 07120
S E C T I O N 2 . CO M P O S I T I O N / I N F O R M AT I O N O N I N G R E D I E N T S
CAS # Component Percent
75-12-7 Formamide 5-25
9048-46-8 Albumin, bovine, fraction v <5
Component Information/Information on Non-Hazardous Components
This product has been evaluated under the criteria specified in 29 CFR 1910.1200 (Hazard Communication
Standard). Other components in this product are considered non-hazardous, under the criteria specified in
29 CFR 1910.1200 (Hazard Communication), or are below the lower limits prescribed by OSHA.
This product contains materials derived from biological origins.
S E C T I O N 3 . H A Z A R D S I D E N T I F I C AT I O N
Emergency Overview
This product is a clear, non-flammable liquid with no odor. This product may be irritating to the eyes,
respiratory system and skin. May be harmful if absorbed through the skin. Use methods suitable to fight
surrounding fire.
Hazard Statements
This product may be irritating to the eyes, respiratory system and skin. May be harmful if absorbed through
the skin.
Potential Health Effects: Eyes
This product may cause irritation to the eyes.
Potential Health Effects: Skin
Contact with this product may cause irritation to the skin. A component of this product may be absorbed
through the skin.
Potential Health Effects: Ingestion
May be harmful if swallowed. Acute overexposure may result in nausea, vomiting and diarrhea.
Potential Health Effects: Inhalation
Inhalation of vapors or mists of the product may be irritating to the respiratory system.
HMIS Ratings: Health: 1* Fire: 1 Physical Hazard: 0 Pers. Prot.: gloves, goggles
Hazard Scale: 0 = Minimal, 1 = Slight, 2 = Moderate, 3 = Serious, 4 = Severe, * = Chronic hazard
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Material Name: Pronto!鈩? Short Oligo Hybridization Solution ID: C-314
S E C T I O N 4 . F I R ST A I D M E A S U R E S
First Aid: Eyes
In case of contact, immediately flush eyes with large amounts of water, continuing to flush for 15 minutes. Get
medical attention or advice.
First Aid: Skin
Immediately flush exposed area with large amounts of water while removing contaminated clothing. Get
medical attention or advice. Launder contaminated clothing before reuse.
First Aid: Ingestion
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Get immediate medical
attention. Never give anything by mouth to a victim who is unconscious or is having convulsions.
First Aid: Inhalation
If inhaled, remove person to fresh air. If symptoms develop or persist, get medical attention.
SECTION 5. FIRE FIGHTING MEASURES
Flash Point: 154潞C (309潞F) (Formamide) Method Used: Open cup
Upper Flammable Limit (UFL): Not determined Lower Flammable Limit (LFL): Not determined
Auto Ignition: Not available Flammability Classification: Non-flammable
Rate of Burning: Not available
General Fire Hazards
Non-flammable but may burn at elevated temperatures.
Hazardous Combustion Products
Carbon monoxide, carbon dioxide, nitrogen oxides, ammonia, hydrogen cyanide and other hydrocarbon
fragments.
Extinguishing Media
Water fog, foam, dry chemical or carbon dioxide.
Fire Fighting Equipment/Instructions
Wear full protective clothing, including helmet, self-contained positive pressure or pressure demand breathing
apparatus, protective clothing and face mask. Cool fire-exposed containers with water.
NFPA Ratings: Health: 1 Fire: 1 Reactivity: 0
Hazard Scale: 0 = Minimal, 1 = Slight, 2 = Moderate, 3 = Serious, 4 = Severe
S E C T I O N 6 . A CC I D E N TA L R E L E A S E M E A S U R E S
Containment Procedures
Contain the discharged material.
Clean-Up Procedures
Clean-up personnel should wear suitable protective equipment. Collect spilled material with an inert absorbent
such as sand or vermiculite. Place in properly labeled closed container. Flush area with water to remove trace
residue.
Evacuation Procedures
Keep unnecessary personnel away.
Special Procedures
Clean up and dispose of waste in accordance with all Federal, State and local regulations.
S E C T I O N 7. H A N D L I N G A N D STO R A G E
Handling Procedures
Avoid contact with skin and eyes. Avoid inhalation of mists or vapors. Wash thoroughly after handling. Keep
container closed. Use only with adequate ventilation. Mix well before using.
Storage Procedures
Store in a cool, dry area.
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Material Name: Pronto!鈩? Short Oligo Hybridization Solution ID: C-314
S E C T I O N 8 . E X P O S U R E CO N T R O L S / P E R S O N A L P R OT E C T I O N
Exposure Guidelines
A: General Product Information
Follow all applicable exposure limits.
B: Component Exposure Limits
Formamide (75-12-7)
ACGIH: 10 ppm TWA
skin - potential for cutaneous absorption
NIOSH: 10 ppm TWA; 15 mg/m3 TWA
Potential for dermal absorption
OSHA: 20 ppm TWA; 30 mg/m3 TWA
(Vacated) 30 ppm STEL; 45 mg/m3 STEL
Engineering Controls
Use local exhaust ventilation to keep exposures to a minimum.
Personal Protective Equipment
Personal Protective Equipment: Eyes/Face
Wear safety glasses or goggles.
Personal Protective Equipment: Skin
Use impervious gloves when handling. Use of protective coveralls and long sleeves is recommended to prevent
skin contact.
Personal Protective Equipment: Respiratory
When exposure to aerosols or vapors is possible, use a NIOSH approved organic vapor respirator.
Personal Protective Equipment: General
Eye wash fountain and emergency showers are recommended.
S E C T I O N 9 . P H Y S I C A L & C H E M I C A L P R O P E RT I E S
Appearance: Clear Odor: None
Physical State: Liquid pH: 8
Vapor Pressure: Not determined Vapor Density: Not determined
Boiling Point: Not determined Solubility (H2O): Soluble
Freezing Point: Not determined Molecular Weight: Mixture
1 gm/cm3
Density:
S E C T I O N 1 0. C H E M I C A L STA B I L I T Y & R E A C T I V I T Y I N F O R M AT I O N
Chemical Stability
Stable under normal conditions.
Chemical Stability: Conditions to Avoid
Keep away from heat, ignition sources and incompatible materials.
Incompatibility
Avoid contact with oxidizing agents, acids, bases, iodine, pyridine, and sulfur trioxide. Formamide can react
with copper, brass, lead and rubber.
Hazardous Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, nitrogen oxides, ammonia, hydrogen
cyanide and other hydrocarbon fragments.
Hazardous Polymerization
Will not occur.
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Material Name: Pronto!鈩? Short Oligo Hybridization Solution ID: C-314
S E C T I O N 1 1 . TOX I CO LO G I C A L I N F O R M AT I O N
Acute Toxicity
A: General Product Information
No additional information.
This product contains materials derived from biological origin that may contain low levels of infectious agents,
and should be handled in keeping with safe laboratory practices.
B: Component Analysis - LD50/LC50
Formamide (75-12-7)
Oral LD50 Rat: 5577 mg/kg
Oral LD50 Mouse: 3150 mg/kg
Carcinogenicity
A: General Product Information
No information available for product.
B: Component Carcinogenicity
None of this product鈥檚 components are listed by ACGIH, IARC, OSHA, NIOSH, or NTP.
Epidemiology
No information available for product.
Neurotoxicity
No information available for product.
Mutagenicity
No information available for product.
Teratogenicity
No information available for product.
Formamide has been reported to cause birth defects in experimental animals following oral and dermal
administration.
Other Toxicological Information
None.
S E C T I O N 1 2 . E CO LO G I C A L I N F O R M AT I O N
Ecotoxicity
A: General Product Information
No information available for product.
B: Component Analysis - Ecotoxicity - Aquatic Toxicity
No ecotoxicity data are available for this product鈥檚 components.
Environmental Fate
No information available for product.
S E C T I O N 1 3 - D I S P O S A L CO N S I D E R AT I O N S
US EPA Waste Number & Descriptions
A: General Product Information
No additional information. You must test your waste using methods described in 40 CFR Part 261 to
determine if it meets applicable definitions of hazardous wastes.
B: Component Waste Numbers
No EPA Waste Numbers are applicable for this product鈥檚 components.
Disposal Instructions
Waste must be handled in accordance with all federal, state, provincial, and local regulations.
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Material Name: Pronto!鈩? Short Oligo Hybridization Solution ID: C-314
S E C T I O N 1 4 . T R A N S P O RTAT I O N I N F O R M AT I O N
US DOT Information
Shipping Name: Not regulated as a hazardous material for transportation.
S E C T I O N 1 5 . R E G U L ATO RY I N F O R M AT I O N
US Federal Regulations
A: General Product Information
All components of this product are on the TSCA Inventory or are exempt from TSCA Inventory requirements.
B: Component Analysis
None of this products components are listed under SARA Section 302 (40 CFR 355 Appendix A), SARA
Section 313 (40 CFR 372.65), or CERCLA (40 CFR 302.4).
State Regulations
A: General Product Information
Other state regulations may apply. Check individual state requirements.
B: Component Analysis - State
The following components appear on one or more of the following state hazardous substances lists:
Component CAS CA MA MN NJ PA RI
Formamide 75-12-7 Yes Yes Yes Yes Yes Yes
Other Regulations
A: General Product Information
No additional information.
B: Component Analysis - Inventory
Component CAS # TSCA DSL EINECS
Formamide 75-12-7 Yes Yes Yes
Albumin, bovine, fraction v 9048-46-8 Yes Yes Yes
C: Component Analysis - WHMIS IDL
The following components are identified under the Canadian Hazardous Products Act Ingredient Disclosure List:
Component CAS # Minimum Concentration
Formamide 75-12-7 0.1% (English Item 782, French Item 919)
S E C T I O N 1 6 . OT H E R I N F O R M AT I O N
Other Information
Reasonable care has been taken in the preparation of this information, but Corning makes no warranty of
merchantability or any other warranty, expressed or implied, with respect to this information. Corning makes no
representations and assumes no liability for any direct, incidental or consequential damages resulting from its use.
Revision information
Revision 1.0001, 27-OCT-2003: Name Change.
Revision 1.0000, 08-OCT-2003: New MSDS
Key/Legend
ACGIH = American Conference of Governmental Industrial Hygienists; CAS = Chemical Abstracts Service;
CERCLA = Comprehensive Environmental Response, Compensation, and Liability Act; CFR = Code of Federal
Regulations; CPR = Controlled Products Regulations; DOT = Department of Transportation; DSL = Domestic
Substances List; EINECS = European Inventory of Existing Commercial Chemical Substances; EPA = Environ-
mental Protection Agency; IARC = International Agency for Research on Cancer; IATA = International Air
Transport Association; mg/Kg = milligrams per Kilogram; mg/L = milligrams per Liter; mg/m3 = milligrams
per Cubic Meter; MSHA = Mine Safety and Health Administration; NA = Not Applicable or Not Available;
NIOSH = National Institute for Occupational Safety and Health; NJTSR = New Jersey Trade Secret Registry;
NTP = National Toxicology Program; OSHA = Occupational Safety and Health Administration; SARA =
Superfund Amendments and Reauthorization Act; TDG = Transport Dangerous Goods; TSCA = Toxic
Substances Control Act; WHMIS = Workplace Hazardous Materials Information System.
Contact
Corporate Safety Management Services, (607) 974-6926
This is the end of MSDS # C-314
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