EZ COMPLEMENT
Product No. 789-001
MATERIAL SAFETY DATA SHEET FOR
EZ COMPLEMENT SENSITIZED CELLS:
Sodium Azide (Pgs. 2 鈥? 8)
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
THE FOLLOWING COMPOUND IS FOUND IN OUR
EZ COMPLEMENT SENSITIZED CELLS
SECTION 1 : PRODUCT IDENTIFICATION
Name: Sodium azide
Synonyms: Azide, sodium, Smite, RCRA Waste No. P105
CAS No.: 26628-22-8 EC No.: 247-852-1
Molecular Weight: 65.01
Chemical Formula: NaN3
Product Codes: 0639
Manufacturer Information:
Amresco Inc.
30175 Solon Industrial Parkway
Solon, Ohio 44139
For Information: (800) 448-4442 or (440) 349-1199
Emergency Telephone Number: CHEMTREC 鈥? (800) 424-9300
SECTION 2 : COMPOSITION/INFORMATION ON INGREDIENTS
Ingredient: Sodium Azide
CAS No.: 26628-22-8
Percent: >99 %
Hazardous: Yes
SECTION 3 : HAZARDS IDENTIFICATION
Label Precautionart Statements:
HIGHLY TOXIC (USA),
VERY TOXIC (EU),
IRRITANT, IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
MAY CAUSE HERITABLE GENETIC DAMAGE.
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN, AND IF SWALLOWED
CONTACT WITH ACID LIBERATES VERY TOXIC GAS.
HEATING MAY CAUSE AN EXPLOSION
READILY ABSORBED THROUGH SKIN.
AVOID CONTACT WITH METALS.
TARGET ORGANS: NERVES, HEART.
IN CASE OF ACCIDENT , OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY
(SHOW LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROTECTION.
DO NOT BREATHE DUST.
EZ COMPLEMENT, PAGE 2
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
SECTION 4 : FIRST AID MEASURES
Skin Contact:
In case of contact immediately flush eyes or skin with copious amounts of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash contaminated clothing
before re-use.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical attention immediately.
Ingestion:
If swallowed, wash out mouth with water provided the person is conscious. Call a physician
SECTION 5 : FIRE FIGHTING MEASURES
Fire Extinguishing Media:
Do not use water.
Dry chemical powder.
Special Firefighting Procedures:
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and
eyes.
Unusual Fire and Explosions Hazards:
Container explosion may occur under fire conditions. Emits toxic fumes under fire conditions.
SECTION 6 : ACCIDENTAL RELEASE MEASURES
Instructions:
Evacuate Area
Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves.
Spills:
Sweep up, place into a bag and hold for waste disposal.
Avoid raising dust.
Ventilate area and wash spill site after material pickup is complete.
SECTION 7 : HANDLING AND STORAGE
(Refer to Section 8)
Additional Information:
Azide reacts with many heavy metals such as lead, copper, mercury, silver, and gold to form
explosive compounds. Copper and lead azides are more sensitive than nitroglycerine. Azide reacts
with metal halides to give a range of metal azide halides, many of which are explosive. Incompatible
with chromyl chloride, hydrazine, bromine, carbon disulfide, dimethyl sulfate, dibromomalonitrile. An
explosion occurred when a mixture of sodium azide, methylene chloride, dimethyl sulfoxide and
sulfuric acid were being concentrated on a rotary evaporator.
EZ COMPLEMENT, PAGE 3
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
SECTION 8 : EXPOSURE CONTROLS/PERSONAL PROTECTION
Wear appropriate NIOSH/MSHA-approved respirator, chemical-resistant gloves, safety goggles,
other protective clothing.
Use only in chemical fume hood.
Maintain safety shower and eye bath.
Do not breathe dust.
Do not get into eyes, on skin or on clothing.
Avoid prolonged or repeated exposure.
Wash thoroughly after handling.
Highly toxic.
Irritant.
Keep tightly closed.
Heat-sensitive.
Store in a cool, dry place.
SECTION 9 : PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Solid.
Odor: Odorless.
Solubility: 42 g/100 g water @ 17C (63F)
Specific Gravity: 1.85
SECTION 10 : STABILITY AND REACTIVITY
Incompatibilities:
Acid chlorides
Halogenated solvents
Avoid contact with metals
Avoid contact with acid
Explodes when heated.
Hazardous Decomposition Products:
Nitrogen oxides
EZ COMPLEMENT, PAGE 4
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
SECTION 11 : TOXICOLOGICAL INFORMATION
Acute Effects: May be fatal if inhaled, swallowed or absorbed through skin.
Causes eye and skin irritation.
Material is irritating to mucous membranes and upper respiratory tract.
Exposure can cause nausea, headache and vomiting.
Chronic effects:
May alter genetic material.
Target organs: Nerves, heart, brain
Additional Information:
Laboratory experiments in animals have shown sodium azide to produce a profound
hypotensive effect, demyelination of myelinated nerve fibers in the central nervous
system, testicular damage, blindness, attacks of rigidity, hepatic and cerebral effects.
RTECS #: VY8050000 SODIUM AZIDE
Toxicity Data:
ORL-WMN LDLO: 786 mg/kg (1989) & 14 mg/kg (1990)
ORL-MAN LDLO: 29 mg/kg (1989) & 129 mg/kg (1996) & 143 mg/kg (1986)
ORL-RAT LD50: 27 mg/kg (1991)
ORL-MUS LD50: 27 mg/kg (CLDND)
ORL-BWD LD50: 23700 ug/kg (1983)
SCU-RAT LD50: 45100 ug/kg (1961)
SCU-MUS LD50: 23060 ug/kg (1961)
ITR-RAT LD50: 47500 ug/kg (1961)
IPR-MUS LD50: 28mg/kg (1948)
IVN-MUS LD50: 19mg/kg (CLDND)
UNR-MUS LD50: 27 mg/kg (1952)
SKIN-RBT LD50: 20 mg/kg (1991)
Target Organ Data:
Brain and coverings (increased cranial pressure)
Peripheral nerve & sensation [spastic paralysis with/without sensory sense organs
and special senses (mydriasis)]
Behavioral (general anesthetic, somnolence, convulsions or effect on seizure
threshold, change in motor activity, coma, headache, irritability)
Cardiac (arrythmias, pulse rate decreased with fall in BP, change in force of
contraction, other changes)
Vascular (BP lowering)
Respiratory, Lungs, Thorax (acute pulmonary edema, dyspnae, respiratory
stimulation, other changes)
EZ COMPLEMENT, PAGE 5
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
SECTION 11 : TOXICOLOGICAL INFORMATION (cont.)
Gastrointestinal (hypermotility, diarrhea)
Kidney, Ureter, Bladder (other changes)
Only selected registry of toxic effects of chemical substances (RTECS) data is
presented here. See actual entry in RTECS for complete information.
SECTION 12 : ECOLOGICAL INFORMATION
Data not yet available.
SECTION 13 : DISPOSAL CONSIDERATIONS
Contact a licensed, professional waste disposal service to dispose of this material.
Observe all Federal, State and local environmental regulations.
SECTION 14 : TRANSPORT INFORMATION
Domestic (Land, D.O.T.)
Proper Shipping Name: SODIUM AZIDE
Hazard Class: 6.1
UN/NA: UN1687
Packing Group: II
SECTION 15 : REGULATORY INFORMATION
European Information:
Ingredient: Sodium Azide (26628-22-8)
EC Index #: 011-004-00-7 Very Toxic
R: 26/27/28 -Very toxic by inhalation, in contact with skin and if swallowed. Irritant.
R: 36/37/38 -Irritating to eyes, respiratory system and skin
R: 40 -Possible risk of irreversible effects
S: 36/37/39 -Wear suitable protective clothing, gloves and eye/face protection.
EZ COMPLEMENT, PAGE 6
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
SECTION 15 : REGULATORY INFORMATION (cont.)
Reviews, Standards, and regulations:
OEL = MAK
OEL-Australia (TWA 0.1 ppm, 1993), Belgium (STEL 0.1 ppm, 1993), Denmark
(TWA 0.3 mg/m3, 1993), Finland (TWA 0.1 ppm, 1993), France (STEL 0.1ppm,
1993), Germany (TWA 0.07 ppm, 1993), Netherlands (TWA 0.1 ppm, 1993),
Switzerland (TWA 0.1 ppm, 1993), UK (TWA 0.1 ppm, 1993), in Bulgaria,
Colombia, Jordan, Korea, New Zealand, Singapore, Vietnam check ACGIH TLV
NIOSH: Rel to Sodium Azide, as HN3-Air:CL 0.1 ppm (SK)
NIOSH DHHS # 92-100, 1992
NOHS 1974: HZD 68820; NIS 13; TNF 877; NOS 10; TNE 5953
NOES 1983: HZD 68820; NIS 19; TNF 3640; NOS 27; TNE54959; TFE 38370
EPA GENETOX PROGRAM 1988:
Positive: L5178Y cells in vitro-TK test, d-melanogaster sex-linked lethal, S.
cerevisiae gene conversion and forward mutation and reversion
Negative: In vitro cytogenetics-human lymphocyte, sperm morphology-
mouse, in vitro UDS-human fibroblast, TRP reversion
Inconclusive: carcinogenicity-mouse/rat, TRP reversion
EPA TSCA Section 8(B) Chemical Inventory
EPA TSCA Section 8(D) Unpublished health/safety studies on EPA IRIS
database
EPA TSCA Test submission (TSCATS) database, Apr 1997
NIOSH Current Intelligence Bulletin 13, 1976
NTP Carcinogenesis studies (GAVAGE): No evidence: Rat 鈥揘TPTR NTP-TR-
389,91
U.S Information
This product is subject to SARA Section 313 reporting requirements
SECTION 16 : OTHER INFORMATION
No additional data available.
EZ COMPLEMENT, PAGE 7
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
MATERIAL SAFETY DATA SHEET
SODIUM AZIDE
MSDS Number: Not given
Revision Date: 07/25/03
DISCLAIMER:
Amresco Inc. provides the information contained herein in good faith but makes no
representation as to its comprehensiveness or accuracy. This document is intended only as a
guide to the appropriate precautionary handling of the material by a properly trained person
using this product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose. AMRESCO, INC. MAKES
NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESSED OR IMPLIED, INCLUDING
WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, AMRESCO, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING
FROM USE OF OR RELIANCE UPON THIS INFORMATION.
Prepared by: Amresco Inc
Phone Number: (800) 448-4442 (U.S.A)
Emergency Number: (800) 424-9300 (CHEMTREC)
MSDS-SodiumAzide-Rev0-Dec04
EZ COMPLEMENT, PAGE 8
Diamedix Corporation 鈥? 2140 North Miami Avenue 鈥? Miami, Florida 33127 鈥? Tel: (305) 324-2300 鈥? (800) 327-4565 鈥? Fax: (305) 324-2385 鈥? www.diamedix.com
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