Updated: September 24, 2007
Attn: SAFETY DIRECTOR
MATERIAL SAFETY DATA SHEET
CATALOG NUMBERS: 2012
PRODUCT NAME: HQ SILVER SILVER ENHANCEMENT REAGENT
Please note that the disposal instructions and information in this sheet refer to the HQ Silver
reagent as used after the components have been mixed, and not to the components individually.
The formulation is proprietary but appropriate instructions and cautions for handling and disposal
are given below.
SECTION 1: IDENTIFICATION
HQ Silver is a proprietary formulation containing a number of compounds.
SECTION 2: COMPOSITION
HQ Silver contains a silver salt and an organic reducing agent. The concentration of each of
these components in the reagent mixture is as follows:
Silver as Ag+ ions: 0.054 % (0.16 % of solution C)
Organics (reducing agent): 0.77 % (2.3 % of solution A)
This solution also contains acetonitrile as shown below:
Acetonitrile: 0.26 % (0.77 % of solution C)
Please refer to the materials safety data sheet for acetonitrile.
This solution also contains the following compounds in low concentrations (less than 0.1 %
in components):
Butylated hydroxyanisole (BHA)
n-propyl p-hydroxybenzoate (propyl paraben)
p-methoxy-benzoate methyl ester (methyl paraben)
Other compounds present include commonly used buffer salts giving sodium, lactate, and N-
(2-Hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid) (HEPES) in solution. Please refer to
the materials safety data sheets for these compounds.
MSDS: 2012 HQ Silver Updated: September 24, 2007
SECTION 3: HAZARDS IDENTIFICATION
Caution: Substance not fully tested.
Toxic.
Possible carcinogen (US).
Harmful by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
Irritating to eyes and respiratory system.
Severe skin irritant.
Target organ (s): Nerves, Kidneys, Eyes.
Avoid exposure - obtain special instructions before use. In case of accident of if you feel
unwell, seek medical advice immediately.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Do not breathe dust.
SECTION 4 FIRST AID MEASURES
In case of contact, immediately flush eyes with copious amounts of water for at least 15
minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
In case of contact, immediately wash skin with soap and copious amounts of water. Remove
contaminated clothing and shoes. Call a physician.
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is
difficult, give oxygen.
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Wash contaminated clothing before reuse.
SECTION 5 FIRE FIGHTING MEASURES
Extinguishing media:
Water spray, carbon dioxide, dry powder or appropriate foam.
Special firefighting procedures:
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin
and eyes.
Unusual fire and explosions hazards:
Emits toxic fumes under fire conditions.
SECTION 6 ACCIDENTAL RELEASE MEASURES
Evacuate area
Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves.
Absorb onto combustible material, place in a bag and hold for waste disposal.
Avoid raising dust.
Evacuate area.
Ventilate area and wash spill site after material pickup is complete.
SECTION 7 HANDLING AND STORAGE
Refer to section 8.
SECTION 8 EXPOSURE CONTROLS/PERSONAL PROTECTION
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MSDS: 2012 HQ Silver Updated: September 24, 2007
Chemical safety goggles.
Rubber gloves.
NIOSH/MSHA-approved respirator.
Safety shower and eye bath.
Mechanical exhaust required.
Do not breathe dust.
Do not get in eyes, on skin, on clothing.
Wash thoroughly after handling.
Keep tightly closed.
Irritant.
Light sensitive.
Store at -20掳C.
SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES
Appearance:
Solution A - initiator: Colorless liquid
Solution B - Moderator: Pale brown viscous liquid.
Solution C - Activator: Pale brown viscous liquid.
Stability:
Stable.
Incompatibilities:
Strong oxidizing agents.
Light sensitive.
Air sensitive.
Strong acids.
Strong bases.
Hazardous combustion or decomposition products:
Toxic fumes of:
Carbon monoxide, carbon dioxide
Nitrogen oxides
Sulfur oxides
Hazardous polymerization:
Will not occur.
SECTION 11 TOXICOLOGICAL INFORMATION
Acute effects:
Harmful by inhalation and if swallowed
May be harmful by ingestion or skin absorption.
Causes eye and skin irritation.
Material is irritating to mucous membranes and upper respiratory tract.
May cause argyria (a slate-gray or bluish discoloration of the skin and deep tissues due to the
deposit of insoluble albuminate of silver).
May cause allergic reaction.
Prolonged exposure can cause:
Damage to the eyes
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MSDS: 2012 HQ Silver Updated: September 24, 2007
To the best of our knowledge, the chemical, physical and toxicological properties have not
been thoroughly investigated.
Chronic effects
Target organ(s):
Kidneys.
Eyes.
This product is or contains a component that has been reported to be possibly carcinogenic
based on its IARC, ACGIH, NTP or EPA classification.
Additional information:
One component (thickening agent) reported to be a weak allergen.
Inhalation of dust can cause respiratory problems with symptoms such as asthma, cough,
wheezing, watery eyes and nose. Angiodema, eczema and hives can result from inhalation or
ingestion.
SECTION 12 ECOLOGICAL INFORMATION
Data not available.
SECTION 13 DISPOSAL CONSIDERATIONS
Absorb the material on an inert combustible material, or dissolve or mix with a combustible
solvent and burn in a chemical incinerator equipped with an after burner and scrubber.
Observe all Federal, State and Local environmental regulations.
Catalysts and expensive metals should be recovered for reuse or recycling.
SECTION 14 TRANSPORT INFORMATION
Contact Nanoprobes, Incorporated for transportation information.
The above information is believed to be correct but does not purport to be all inclusive and shall
be used only as a guide. Nanoprobes, Inc. shall not be held liable for any damage resulting from
handling or from contact with the above product.
Copyright 1995, 2007 Nanoprobes, Incorporated.
License granted to make unlimited paper copies for internal use only.
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