Material Safety Data Sheet
Isoprene
Section 1. Chemical product and company identification
: Isoprene
Product Name
: AIRGAS INC., on behalf of its subsidiaries
Supplier
259 North Radnor-Chester Road
Suite 100
Radnor, PA 19087-5283
1-610-687-5253
: 1,3-butadiene, 2-methyl-; isoprene (dot); beta-methylbivinyl; 2-methylbutadiene; 2-methyl-
Synonym
1,3-butadiene
: Other non specified industry: MONOMER FOR MANUFACTURE OF POLYISOPRENE;
Material uses
CHEMICAL INTERMEDIATE; COMPONENT OF BUTYL RUBBER.
: 001128
MSDS#
Date of : 1/4/2007.
Preparation/Revision
: 1-866-734-3438
In case of emergency
Section 2. Hazards identification
: Liquid. (COLORLESS WATER LIQUID WITH A MILD ODOR)
Physical state
: Danger!
Emergency overview
HIGHLY FLAMMABLE LIQUID AND VAPOR.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: MUCOUS MEMBRANES,
RESPIRATORY TRACT, EYE, LENS OR CORNEA, NOSE, SINUSES.
SUSPECT CANCER HAZARD.
MAY CAUSE CANCER.
VAPOR MAY CAUSE FLASH FIRE.
Keep away from heat, sparks and flame. Keep container closed. Use only with
adequate ventilation. Risk of cancer depends on duration and level of exposure.
: Inhalation. Ingestion.
Routes of entry
Potential acute health effects
Irritating to eyes.
Eyes :
Irritating to skin.
Skin :
Practically non-toxic by inhalation.
Inhalation :
MAY BE HARMFUL IF SWALLOWED.
:
Ingestion
CARCINOGENIC EFFECTS Classified 2B (Possible for human.) by IARC. Classified 2
:
Potential chronic health :
(Reasonably Anticipated To Be Human Carcinogens.) by NTP.
effects
MUTAGENIC EFFECTS Not available.
:
TERATOGENIC EFFECTS Not available.
:
: Repeated exposure to a highly toxic material may produce general deterioration of health
Medical conditions
aggravated by overexposure by an accumulation in one or many human organs.
See toxicological Information (section 11)
Section 3. Composition, Information on Ingredients
United States
Exposure limits
isoprene (stabilized) 78-79-5 100 AIHA WEEL (United States, 1/2005). Notes:
2004 Revised Document
TWA: 2 ppm 8 hour(s). Form: All forms
Isoprene
Section 4. First aid measures
: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes.
Eye contact
Get medical attention if irritation occurs.
: In case of contact, immediately flush skin with plenty of water. Remove contaminated
Skin contact
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Get medical attention.
: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is
Inhalation
difficult, give oxygen. Get medical attention if symptoms appear.
: Do NOT induce vomiting unless directed to do so by medical personnel. Never give
Ingestion
anything by mouth to an unconscious person. Get medical attention if symptoms
appear.
Section 5. Fire fighting measures
Flammable.
Flammability of the product :
219.85掳C (427.7掳F)
Auto-ignition temperature :
Closed cup: -53.15掳C (-63.7掳F).
Flash point :
Lower: 2% Upper: 9%
Flammable limits :
These products are carbon oxides (CO, CO 2).
Products of combustion :
In case of fire, use water spray (fog), foam, dry chemicals, or CO 2.
Fire fighting media and :
instructions
Highly flammable liquid and vapor. Vapor may cause flash fire. Vapors may accumulate
in low or confined areas, travel considerable distance to source of ignition and flash
back. Runoff to sewer may create fire or explosion hazard.
: Fire fighters should wear appropriate protective equipment and self-contained breathing
Special protective
apparatus (SCBA) with a full facepiece operated in positive pressure mode.
equipment for fire-fighters
Section 6. Accidental release measures
: Immediately contact emergency personnel. Eliminate all ignition sources. Keep
Personal precautions
unnecessary personnel away. Use suitable protective equipment (Section 8). Do not
touch or walk through spilled material.
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers.
: If emergency personnel are unavailable, contain spilled material. For small spills add
Methods for cleaning up
absorbent (soil may be used in the absence of other suitable materials) and use a non-
sparking or explosion proof means to transfer material to a sealed, appropriate container
for disposal. For large spills dike spilled material or otherwise contain material to ensure
runoff does not reach a waterway. Place spilled material in an appropriate container for
disposal.
Section 7. Handling and storage
: Keep container closed. Use only with adequate ventilation. Keep away from heat,
Handling
sparks and flame. To avoid fire or explosion, dissipate static electricity during transfer by
grounding and bonding containers and equipment before transferring material. Use
explosion-proof electrical (ventilating, lighting and material handling) equipment.
: Store in a segregated and approved area. Keep container in a cool, well-ventilated area.
Storage
Keep container tightly closed and sealed until ready for use. Avoid all possible sources
of ignition (spark or flame).
Section 8. Exposure Controls, Personal Protection
: Provide exhaust ventilation or other engineering controls to keep the airborne
Engineering controls
concentrations of vapors below their respective occupational exposure limits. Ensure
that eyewash stations and safety showers are proximal to the work-station location.
Personal protection
: Safety eyewear complying with an approved standard should be used when a risk
Eyes
assessment indicates this is necessary to avoid exposure to liquid splashes, mists or
dusts.
Isoprene
: Personal protective equipment for the body should be selected based on the task being
Skin
performed and the risks involved and should be approved by a specialist before handling
this product.
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
Respiratory
standard if a risk assessment indicates this is necessary.Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
: Chemical-resistant, impervious gloves or gauntlets complying with an approved standard
Hands
should be worn at all times when handling chemical products if a risk assessment
indicates this is necessary.
Personal protection in case : Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self-contained breathing
apparatus should be used to avoid inhalation of the product. Suggested protective
of a large spill
clothing might not be sufficient; consult a specialist BEFORE handling this product.
Product name Exposure limits
United States
isoprene (stabilized) AIHA WEEL (United States, 1/2005). Notes: 2004 Revised Document
TWA: 2 ppm 8 hour(s). Form: All forms
Section 9. Physical and chemical properties
Liquid. (COLORLESS WATER LIQUID WITH A MILD ODOR)
Physical state :
MILD, AROMATIC
Odor :
68.13 g/mole
Molecular weight :
C5-H8
Molecular formula :
33.85掳C (92.9掳F)
Boiling/condensation point :
-120.15掳C (-184.3掳F)
Melting/freezing point :
211.2掳C (412.2掳F)
Critical temperature :
0.681 (Water = 1)
Specific gravity :
74.6 kPa (560 mm Hg) (at 20掳C)
Vapor pressure :
2.4 (Air = 1)
Vapor density :
Section 10. Stability and reactivity
: The product is stable.
Stability and reactivity
Incompatibility with various : Highly reactive with oxidizing agents.
substances
Hazardous polymerization : Will not occur.
Section 11. Toxicological information
Ingredient name Test Result Route Species
isoprene (stabilized) LC50 127080 ppm (1 Inhalation Rat
hour(s))
Chronic effects on humans : CARCINOGENIC EFFECTS Classified 2B (Possible for human.) by IARC. Classified 2
:
(Reasonably Anticipated To Be Human Carcinogens.) by NTP.
Causes damage to the following organs: mucous membranes, upper respiratory tract,
eye, lens or cornea, nose/sinuses.
: Not considered to be toxic for humans.
Other toxic effects on
humans
Specific effects
: May cause cancer. Risk of cancer depends on duration and level of exposure.
Carcinogenic effects
: No known significant effects or critical hazards.
Mutagenic effects
: No known significant effects or critical hazards.
Reproduction toxicity
Isoprene
Section 12. Ecological information
Ingredient name Species Period Result
isoprene (stabilized) Lepomis macrochirus (LC50) 96 hour(s) 42.54 mg/l
Pimephales promelas (LC50) 96 hour(s) 74.83 mg/l
Pimephales promelas (LC50) 96 hour(s) 75 mg/l
Pimephales promelas (LC50) 96 hour(s) 77 mg/l
Pimephales promelas (LC50) 96 hour(s) 78 mg/l
Pimephales promelas (LC50) 96 hour(s) 80 mg/l
: These products are carbon oxides (CO, CO 2) and water.
Products of degradation
: The product itself and its products of degradation are not toxic.
Toxicity of the products of
biodegradation
Section 13. Disposal considerations
: The generation of waste should be avoided or minimized wherever possible. Avoid
Waste disposal
dispersal of spilled material and runoff and contact with soil, waterways, drains and
sewers. Disposal of this product, solutions and any by-products should at all times
comply with the requirements of environmental protection and waste disposal legislation
and any regional local authority requirements.
Consult your local or regional authorities.
Section 14. Transport information
Regulatory UN number Proper shipping Class Packing group Label Additional
information name information
DOT Classification UN1218 ISOPRENE, 3 I Reportable
STABILIZED quantity
FLAMMABLE LIQUID
100 lbs. (45.36
3
kg)
Limited
quantity
Yes.
Packaging
instruction
Passenger
Aircraft
Quantity
limitation: 1 L
Cargo Aircraft
Quantity
limitation: 30 L
Special
provisions
T11, TP2
TDG Classification UN1218 ISOPRENE, 3 I Explosive
STABILIZED Limit and
Limited
3
Quantity
Index
0
Passenger
Carrying Ship
Index
Forbidden
Passenger
Isoprene
Carrying
Road or Rail
Index
1
UN1218 ISOPRENE, 3 I
Mexico Reportable
STABILIZED
Classification quantity
FLAMMABLE LIQUID
100 lbs. (45.36
3
kg)
Limited
quantity
Yes.
Packaging
instruction
Passenger
Aircraft
Quantity
limitation: 1 L
Cargo Aircraft
Quantity
limitation: 30 L
Special
provisions
T11, TP2
Section 15. Regulatory information
United States
: Flammable liquid
HCS Classification
Carcinogen
Target organ effects
: TSCA 8(b) inventory: isoprene (stabilized)
U.S. Federal regulations
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: isoprene (stabilized)
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: isoprene
(stabilized): Fire hazard, reactive, Immediate (Acute) Health Hazard, Delayed (Chronic)
Health Hazard
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: isoprene (stabilized)
Clean air act (CAA) 112 accidental release prevention: isoprene (stabilized)
Clean air act (CAA) 112 regulated flammable substances: isoprene (stabilized)
Clean air act (CAA) 112 regulated toxic substances: No products were found.
: Pennsylvania RTK: isoprene (stabilized): (environmental hazard, generic environmental
State regulations
hazard)
Massachusetts RTK: isoprene (stabilized)
New Jersey: isoprene (stabilized)
WARNING: This product contains a chemical known to the State of California to cause
cancer.
Isoprene
Ingredient name Cancer Reproductive No significant risk Maximum
level acceptable dosage
level
isoprene (stabilized) Yes. No. No. No.
Canada
: Class B-2: Flammable liquid with a flash point lower than 37.8掳C (100掳F).
WHMIS (Canada)
Class D-2A: Material causing other toxic effects (VERY TOXIC).
CEPA DSL: isoprene (stabilized)
Section 16. Other information
: HIGHLY FLAMMABLE LIQUID AND VAPOR.
Label Requirements
CAUSES DAMAGE TO THE FOLLOWING ORGANS: MUCOUS MEMBRANES,
RESPIRATORY TRACT, EYE, LENS OR CORNEA, NOSE, SINUSES.
SUSPECT CANCER HAZARD.
MAY CAUSE CANCER.
VAPOR MAY CAUSE FLASH FIRE.
*1
Hazardous Material : Health
Information System (U.S.A.)
4
Fire hazard
0
Reactivity
C
Personal protection
National Fire Protection :
Flammability
4
Association (U.S.A.)
1 2
Health Instability
Special
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named
supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
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