Eng
Material Safety Data Sheet
Conforms to 93/112/EC and ISO 11014-1
Responsible Name MSDS Administrator
Section 1. Chemical Product and Company Identification
Product Name
L-Cysteine Hydrochloride Monohydrate
Product no. 1852110 42260
Supplier In USA: In Europe: Manufacturer Pierce Biotechnology
Pierce Perbio Science P.O. Box 117
P.O. Box 117 Industriezone III Rockford, IL 61105
Rockford, IL 61105 Industrielaan 27 USA
USA 9320 Erembodegem-Aalst 815.968.0747 or
815.968.0747 or Belgium 1.800.874.3723
1.800.874.3723 Tel:+32 53 83 44 04
Fax:+32 53 83 76 38
In case of emergency CHEMTREC: Print date 11/8/2005
800.424.9300 Validation date 11/8/2005
OUTSIDE US:
MSDS# 3744
202.483.7616
Synonyms L-CYSTEINE, HYDROCHLORIDE
Use of the Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
substance/preparation
Section 2. Composition, Information on Ingredients
Substance/preparation Substance
:
Ingredient name CAS number % EC number Classification
L-Cysteine Hydrochloride monohydrate 7048-04-6 98 - 100 200-157-7 Xi; R36/37/38
Section 3. Hazards identification
United States Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
Emergency overview Warning!
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
CONTAINS MATERIAL WHICH CAUSES DAMAGE TO THE FOLLOWING ORGANS:
MUCOUS MEMBRANES, RESPIRATORY TRACT.
Avoid contact with skin and clothing. Avoid breathing dust. Keep container closed. Use only with adequate ventilation.
Wash thoroughly after handling.
Target organs Contains material which causes damage to the following organs: mucous membranes, upper
respiratory tract.
Routes of entry Dermal contact. Eye contact. Inhalation.
Potential acute health effects
Eyes Irritating to eyes.
Skin Irritating to skin.
Inhalation Irritating to respiratory system.
Ingestion No known significant effects or critical hazards.
Potential chronic health effects
Carcinogenic effects CARCINOGENIC EFFECTS: Classified None. by OSHA, None. by NIOSH [L-Cysteine Hydrochloride monohydrate].
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
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L-Cysteine Hydrochloride
Monohydrate
Medical conditions aggravated Repeated or prolonged exposure is not known to aggravate medical condition.
by overexposure
Over-exposure signs/symptoms Not available.
Europe
Classification Xi; R36/37/38
Physical/chemical hazards Not applicable.
Human health hazards Irritating to eyes, respiratory system and skin.
Environmental hazards Not applicable.
See toxicological Information (section 11)
Section 4. First aid measures
Notice to reader Get immediate medical attention.
Effects and symptoms
Inhalation Hazardous in case of inhalation (lung irritant).
Ingestion Not available.
Skin contact Sensitization of the product: Not available.
Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Eye contact Hazardous in case of eye contact (irritant).
Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition.
First-Aid Measures
Inhalation In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention immediately.
Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Get medical attention if symptoms appear.
Skin contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
Eye contact In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention immediately.
Notes to physician Not available.
Protection of first-aiders Not available.
Section 5. Fire fighting measures
Flammability of the product Non-flammable.
Flash Points Not applicable.
Fire hazards in presence of various Not applicable.
substances
Fire fighting media and instructions Use an extinguishing agent suitable for surrounding fires.
Protective clothing (fire) Not applicable.
Hazardous thermal decomposition These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...), halogenated
products compounds, hydrogen chloride.
Section 6. Accidental release measures
Personal precautions Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Environmental precautions and Use a shovel to put the material into a convenient waste disposal container. Neutralize the residue with a dilute
clean-up methods solution of sodium carbonate.
Small spill and leak Use appropriate tools to put the spilled solid in a convenient waste disposal container. If necessary: Neutralize the
residue with a dilute solution of sodium carbonate.
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L-Cysteine Hydrochloride
Monohydrate
Section 7. Handling and storage
Handling Avoid contact with eyes, skin and clothing. Keep container closed. Use only with adequate ventilation. Avoid
breathing dust. Wash thoroughly after handling.
Storage Keep container tightly closed. Keep container in a cool, well-ventilated area.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Packaging materials
Suitable / Not suitable Use original container.
Section 8. Exposure Controls, Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Exposure Limit Values
Ingredient Name Occupational Exposure Limits
United States
Personal Protection
Splash goggles.
Eyes
Lab coat.
Body
Gloves.
Hands
Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Respiratory
Protective Clothing
(Pictograms)
Section 9. Physical and chemical properties
Physical State and Solid. (Solidcrystalline Color White. Odor Not available.
Appearance powder.)
Taste Not available.
Molecular Weight Not applicable.
Molecular Formula C3 H8 Cl N O2 S-H2 O
pH (1% Soln/Water) 1 to 2 (Conc. (% w/w): 2.5) [Acidic.]
Dispersion Properties See solubility in water.
Solubility Soluble in cold water, hot water.
Section 10. Stability and reactivity
Stability and Reactivity The product is stable.
Conditions to avoid Not available.
Materials to avoid Reactive with oxidizing agents, metals, moisture.
Hazardous Decomposition These products are halogenated compounds, hydrogen chloride.
Products
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L-Cysteine Hydrochloride
Monohydrate
Section 11. Toxicological information
Toxicity to Animals L-Cysteine Hydrochloride monohydrate
LD50: Not available.
LC50: Not available.
Chronic Effects on Humans CARCINOGENIC EFFECTS: Classified None. by OSHA, None. by NIOSH [L-Cysteine Hydrochloride monohydrate].
Contains material which causes damage to the following organs: mucous membranes, upper respiratory tract.
Other Toxic Effects on Humans Hazardous in case of eye contact (irritant), of inhalation (lung irritant).
Special Remarks on Toxicity to Not available.
Animals
Special Remarks on Chronic Not available.
Effects on Humans
Special Remarks on Other Toxic Material is irritating to mucous membranes and upper respiratory tract. (L-Cysteine Hydrochloride monohydrate)
Effects on Humans
Carcinogenicity No known significant effects or critical hazards.
Mutagenicity No known significant effects or critical hazards.
Reproductive toxicity No known significant effects or critical hazards.
Over-exposure
signs/symptoms
Inhalation No known significant effects or critical hazards.
Ingestion No known significant effects or critical hazards.
Skin No known significant effects or critical hazards.
Target organs Contains material which causes damage to the following organs: mucous membranes, upper
respiratory tract.
Section 12. Ecological information
Mobility Not available.
Persistence/degradability Not available.
Bioaccumulative potential Not available.
Ecotoxicity Not available.
Germany water class VCI WGK: No products were found.
Ecotoxicity data
Ingredient name Species Period
Other ecological information
Persistence/degradability
Ingredient name BOD5 COD
Ingredient name Aquatic half-life Photolysis
Bioaccumulative potential
Ingredient name LogPow BCF
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
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L-Cysteine Hydrochloride
Monohydrate
Section 13. Disposal considerations
Waste Stream Not available.
Methods of disposal The generation of waste should be avoided or minimized wherever possible. Avoid dispersal of
spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal of this
product, solutions and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local authority
requirements.
European waste catalogue Not available.
(EWC)
Hazardous waste The classification of the product may meet the criteria for a hazardous waste
Denmark 鈥? Carcinogenic waste Not available.
Denmark - Waste card number Not available.
Denmark - Waste group Not available.
Sweden - thermoset plastic Not available.
waste
Sweden - Waste group Not available.
Austria - Waste catalogue Not available.
Norway - Waste number Not available.
Norway - Hazardous waste The classification of the product may meet the criteria for a hazardous waste
Switzerland - Waste code Not available.
Section 14. Transport information
Contact the supplier for all information regarding the proper transportation method for this material.
1
Section 15. Regulatory information
Label Requirements
R36/37/38- Irritating to eyes, respiratory system and skin.
(Europe)
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37-
Wear suitable gloves.
Irritant
HCS Classification Irritating material
Target organ effects
U.S. Federal Regulations TSCA: No products were found.
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L-Cysteine Hydrochloride
Monohydrate
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State regulations No products were found.
Class D-2B: Material causing other toxic effects (TOXIC).
WHMIS (Canada)
No products were found.
International Regulations
EINECS Not available.
DSCL (EEC) R36/37/38- Irritating to eyes, respiratory system and skin.
International Lists Australia (NICNAS): L-Cysteine Hydrochloride monohydrate
Japan (METI): L-Cysteine Hydrochloride monohydrate
Korea (TCCL): L-Cysteine Hydrochloride monohydrate
Philippines (RA6969): L-Cysteine Hydrochloride monohydrate
State Regulations No products were found.
Section 16. Other information
National Fire Protection
Hazardous Material * 1
Health Flammability
0
Association (U.S.A.)
Information System
0
(U.S.A.) Fire hazard 2 1
Health Instability
0
Reactivity
Special
C
Personal protection
References Not available.
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Full text of R phrases referred R36/37/38- Irritating to eyes, respiratory system and skin.
to in sections 2 and 3 -
Europe
Full text of classifications Xi - Irritant
referred to in sections 2 and 3
- Europe
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Date of Previous Issue 11/8/2005
Validated by MSDS Administrator on 11/8/2005. Verified by MSDS Administrator.
Printed 11/8/2005. Version 1.03
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its
subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and
should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that
exist.
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