Creation Date: 07-18-2007
Revision Date: 07-19-2007
Material Safety Data Sheet
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1. Chemical Product and Company Identification
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Material Name Sphingosine-1-phosphate, [33P]
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01
Version #
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Mixture
CAS #
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NEG381000MC
Item #
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PerkinElmer Life and Analytical Sciences
Identification Of The
710 Bridgeport Avenue
Company/Undertaking
Shelton, CT 06484
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Technical Support 800-762-4000
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CHEMTREC 800-424-9300
Emergency Telephone
Emergency Phone 800-762-4000
Number
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2. Composition / Information on Ingredients
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Hazardous component(s) CAS # Percent PEL TLV
METHANOL, ANHYDROUS, 99.8% 67-56-1 80 - 90 200 ppm 200
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Non-hazardous component(s) CAS # Percent
METHANOL (METHYL ALCOHOL) 67-56-1 0.1 - 1
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TETRABUTYLAMMONIUM HYDROXIDE 2052-49-5 0.1 - 1
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Other components below reportable levels 10 - 20
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3. Hazards Identification
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Potential Short Term Health Effects
Skin
Skin irritation
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Eyes
Eye irritation
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Inhalation
May cause irritation of respiratory tract.
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Ingestion
Do not ingest. Harmful if swallowed.
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Target Organs
Eyes. Respiratory system. Skin.
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4. First Aid Measures
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General advice
Consult a physician.
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First Aid
Skin contact
Rinse with water.
Material ID 17039 Material Name Sphingosine-1-phosphate, [33P]
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MSDS US
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Eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
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Inhalation
Oxygen or artificial respiration if needed. If symptoms persist, get immediate medical attention.
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Ingestion
If a person vomits when lying on his back, place him in the recovery position. Have victim rinse
mouth thoroughly with water.
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5. Fire Fighting Measures
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Suitable extinguishing media
Carbon dioxide (CO2). Water spray. Dry chemical. Foam. Water Fog.
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Specific methods
In the event of fire, cool tanks with water spray. Water mist may be used to cool closed containers.
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6. Accidental Release Measures
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Personal precautions
Use personal protective equipment.
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Environmental precautions
Prevent further leakage or spillage if safe to do so.
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Containment Procedures
Prevent entry into waterways, sewers, basements or confined areas. Stop the flow of material, if
this is without risk.
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7. Handling and Storage
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Handling
Keep away from heat and sources of ignition. Handle and open container with care.
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Storage
Use care in handling/storage.
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8. Exposure Controls / Personal Protection
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Exposure Limit Values
ACGIH - Threshold Limits Values - Time Weighted Averages (TLV-TWA)
METHANOL (METHYL 67-56-1 200 ppm TWA
ALCOHOL)
OSHA - Final PELs - Time Weighted Averages (TWAs)
METHANOL (METHYL 67-56-1 200 ppm TWA; 260 mg/m3 TWA
ALCOHOL)
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Exposure Controls
Engineering measures to reduce exposure
Provide adequate ventilation. Provide adequate local exhaust ventilation to maintain worker
exposure below exposure limits.
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Hygiene measures
Handle in accordance with good industrial hygiene and safety practice.
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Respiratory protection
Wear a positive-pressure supplied-air respirator.
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Hand protection
gloves
Material ID 17039 Material Name Sphingosine-1-phosphate, [33P]
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Eye protection
If splashes are likely to occur, wear: safety glasses
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9. Physical & Chemical Properties
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General Information
Form
Liquid.
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Important health, safety and environmental information
51.8 掳F (11 掳C) estimated
Flash Point
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725 掳F (385 掳C) estimated
Auto Ignition
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Flammable IB
Flammability Class
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148.6 掳F (64.75 掳C) estimated
Boiling Point
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-144.4 掳F (-98 掳C) estimated
Melting Point
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105.9739 hPa estimated
Vapor Pressure
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81.72 % estimated
Volatile Organic
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10. Chemical Stability & Reactivity Information
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Stability
No hazards to be especially mentioned.
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Incompatibility
Strong oxidizing agents.
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Further information
Stable at normal conditions
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11. Toxicological Information
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Acute Toxicity
NIOSH - Selected LD50s and LC50s
METHANOL (METHYL 67-56-1 Inhalation LC50 Rat: 64000 mg/kg/4H; Oral LD50
ALCOHOL) Rat: 5628 mg/kg; Oral LD50 Mouse: 7300 mg/kg;
Dermal LD50 Rabbit: 15800 mg/kg
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Symptoms and Target Organs
NIOSH - Pocket Guide - Target Organs
METHANOL (METHYL 67-56-1 skin, eyes, CNS, GI tract, respiratory system
ALCOHOL)
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Further information
This product has no known adverse effect on human health.
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Material ID 17039 Material Name Sphingosine-1-phosphate, [33P]
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MSDS US
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12. Ecological Information
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Ecotoxicity
Ecotoxicity - Freshwater Fish Species Data
METHANOL (METHYL 67-56-1 96 Hr LC50 fathead minnow (28 days old):29400
ALCOHOL) mg/L (flow-through);96 Hr LC50 rainbow trout
(fingerling):13 mg/L;48 Hr LC50 trout: 8000 mg/L
Ecotoxicity - Microtox Data
METHANOL (METHYL 67-56-1 5 min EC50 Photobacterium phosphoreum: 43000
ALCOHOL) mg/L; 15 min EC50 Photobacterium phosphoreum:
40000 mg/L; 25 min EC50 Photobacterium
phosphoreum: 39000 mg/L
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Ecological Information
This material is not expected to be harmful to aquatic life. Components of this product have been
identified as having potential environmental concerns.
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Other adverse effects
Ecological injuries are not known or expected under normal use.
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13. Disposal Considerations
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Disposal Instructions
Dispose in accordance with all applicable regulations. In accordance with local and national
regulations. If discarded, this product is considered a RCRA ignitable waste, D001. Dispose of this
material and its container at hazardous or special waste collection point.
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14. Transportation Information
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US DOT
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Other Information
Not classified as dangerous in the meaning of transport regulations.
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15. Regulatory Information
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CERCLA/SARA Section 313
Sphingosine-1-phosphate, [33P]
Material
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METHANOL, ANHYDROUS, 99.8%
Ingredient(s)
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US Federal Regulations
All components are on the U.S. EPA TSCA Inventory List.
OSHA Process Safety Standard: This material is not known to be hazardous by the OSHA Highly
Hazardous Process Safety Standard, 29 CFR 1910.119.
CERCLA/SARA - Hazardous Substances and their Reportable Quantities
METHANOL (METHYL 67-56-1 5000 lb final RQ; 2270 kg final RQ
ALCOHOL)
CERCLA/SARA - Section 313 - Emission Reporting
METHANOL (METHYL 67-56-1 1.0 % de minimis concentration
ALCOHOL)
Material ID 17039 Material Name Sphingosine-1-phosphate, [33P]
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MSDS US
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State Regulations
This product does not contain a chemical known to the State of California to cause cancer, birth
defects or other reproductive harm.
Massachusetts - Right To Know List
METHANOL (METHYL 67-56-1 Present
ALCOHOL)
Massachusetts - Toxics Use Reduction Act
METHANOL (METHYL 67-56-1 CERCLA and 313 chemical
ALCOHOL)
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International Regulations
Canada - WHMIS - Ingredient Disclosure List
METHANOL (METHYL 67-56-1 1 % (English Item 1012, French Item 183)
ALCOHOL)
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16. Other Information
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Disclaimer
The information provided in this Material Safety Data Sheet is based on our present knowledge,
and believed to be correct at the date of publication. However, no representation is made
concerning its accuracy and completeness. It is intended as guidance only, and is not to be
considered a warranty or quality specification. All materials may present unknown hazards, and
should be used with caution. Although certain hazards are described, we cannot guarantee that
these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held
liable for any damage resulting from handling or from contact with the product.
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Material ID 17039 Material Name Sphingosine-1-phosphate, [33P]
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MSDS US
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