The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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"VERTREL" X-B3
6107FR Revised 12-NOV-2007
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"VERTREL" is a registered trademark of DuPont.
Formula : CF3CHFCHFCF2CF3,C4H9OCH2CH2OH
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont Fluoroproducts
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
138495-42-8
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (HFC-43- 96-98
10mee)
*2-BUTOXYETHANOL (butyl "cellosolve") 111-76-2 2-4
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
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HAZARDS IDENTIFICATION
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Potential Health Effects
Gross overexposure by inhalation to HFC-43-10mee may cause
suffocation if air is displaced by vapors and central
nervous system stimulation with increased activity or
sleeplessness, tremors or convulsions. These effects may be
followed by central nervous system depression with
dizziness, confusion, incoordination, drowsiness or
unconsciousness. Based on data from other fluorocarbons,
gross overexposure may be associated with irregular
6107FR DuPont Page 2
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
heartbeat or heart rhythm, which may produce heart
palpitation, dizziness, weakness, unconsciousness and death.
It is unlikely that concentrations sufficient to produce
irregular heartbeat or heart rhythm would be achieved from
HFC-43-10MEE without first producing other signs of
toxicity. Immediate effects of overexposure to HFC-43-10mee
by skin contact may include slight irritation with itching,
redness or swelling. Repeated and/or prolonged exposure may
cause defatting of the skin with itching, redness or rash.
Based on animal data, significant skin permeation, and
systemic toxicity after skin contact, appears unlikely.
Immediate effects of overexposure to HFC-43-10mee by eye
contact may include eye irritation with tearing, pain or
blurred vision. The major ingestion hazard of HFC-43-10mee
is aspiration (liquid entering the lungs during ingestion or
vomiting) which may result in "chemical pneumonia." Symptoms
include coughing, gasping, choking, shortness of breath,
bluish discoloration of the skin, rapid breathing and heart
rate, and fever. Pulmonary edema or bleeding, drowsiness,
confusion, coma and seizures may occur in more serious
cases. Symptoms may develop immediately or as late as 24
hours after exposure, depending on how much chemical entered
the lungs. Increased susceptibility to the effects of
HFC-43-10mee may be observed in persons with pre-existing
disease of the central nervous system or the cardiovascular
system.
Human health effects of overexposure to "Cellosolve" by skin
contact may include skin irritation with discomfort or rash.
Evidence suggests that skin permeation can occur in amounts
capable of producing the effects of systemic toxicity.
There are no reports of human sensitization. Exposure to
vapors or eye contact may include eye irritation with
discomfort, tearing, or blurring of vision. Based on animal
data, higher or repeated exposures may cause red blood cell
destruction. The developmental toxicity and the hazard to
males were evaluated and not believed to be significant.
Butyl "Cellosolve" should not be hazardous to adults or the
conceptus in the workplace at the recommended AEL combined
with avoidance of significant skin contact.
# Carcinogenicity Information
The following components are listed by IARC, NTP, OSHA or ACGIH as
carcinogens.
Material IARC NTP OSHA ACGIH
2-BUTOXYETHANOL (butyl "cellosolve") 3 A3
6107FR DuPont Page 3
Material Safety Data Sheet
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FIRST AID MEASURES
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First Aid
INHALATION
If inhaled, immediately remove to fresh air. Keep person calm.
If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Call a physician.
SKIN CONTACT
Flush skin with water after contact. Wash contaminated clothing
before reuse.
EYE CONTACT
In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Call a physician.
INGESTION
Material poses an aspiration hazard. If swallowed, do not induce
vomiting. Immediately give 2 glasses of water. Never give
anything by mouth to an unconscious person. Call a physician.
If vomiting occurs naturally, have victim lean forward to reduce
the risk of aspiration.
Notes to Physicians
THIS MATERIAL MAY MAKE THE HEART MORE SUSCEPTIBLE TO ARRHYTHMIAS.
Catecholamines such as adrenaline, and other compounds having
similar effects, should be reserved for emergencies and then used
only with special caution.
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FIRE FIGHTING MEASURES
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Flammable Properties
Flammable limits in Air, % by Volume
LEL : None.
UEL : None.
Flash Point : None
Method : Pensky Marten Closed Cup (ASTM D 93)
AUTOIGNITION TEMPERATURE:
Has not yet been determined for "Vertrel" X-B3.
Extinguishing Media
Use media appropriate for surrounding material.
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Material Safety Data Sheet
(FIRE FIGHTING MEASURES - Continued)
Fire Fighting Instructions
Self-contained breathing apparatus (SCBA) is required if
drums rupture and contents are spilled under fire
conditions.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Initial Containment
Dike spill. Prevent material from entering sewers, waterways, or
low areas.
Spill Clean Up
Immediately evacuate the area and provide maximum
ventilation, especially in low places where heavy vapors
might collect. Unprotected personnel should move upwind of
spill. Only personnel equipped with proper respiratory and
skin/eye protection should be permitted in area. Soak up
with sawdust, sand, oil dry or other absorbent material.
After all visible traces, including ignitable vapors, have
been removed, thoroughly wet vacuum the area. Do not flush
to sewer. If area of spill is porous, remove as much
contaminated earth and gravel, etc. as necessary and place
in closed containers for disposal.
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HANDLING AND STORAGE
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Handling (Personnel)
Avoid breathing vapors or mist. Avoid contact with eyes, skin, or
clothing. Wash thoroughly after handling.
Handling (Physical Aspects)
The use of gloves is recommended when working with the
material containers. Material should not be dispensed from
its container by pouring, except for small sample containers
where fume hoods or where other ventilation is used to
manage the exposure limits. The use of a drum pump is
recommended for dispensing from shipping containers.
6107FR DuPont Page 5
Material Safety Data Sheet
(HANDLING AND STORAGE - Continued)
Storage
Store in a clean, dry area. Do not allow stored product to
exceed 52 C (125 F) to prevent leakage or potential rupture
of container from pressure and expansion. Protect from
freezing temperatures. If solvent is stored below -10 C
(14 F), mix prior to use.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Personal Protective Equipment
EYE/FACE PROTECTION
Wear coverall chemical splash goggles.
RESPIRATORS
Where there is potential for airborne exposures in excess of
applicable limits, wear NIOSH approved respiratory
protection.
PROTECTIVE CLOTHING
Where there is potential for skin contact have available and
wear as appropriate impervious gloves, apron, pants, and
jacket.
Protective gloves and chemical splash goggles should be used
when handling liquid.
Exposure Guidelines
Applicable Exposure Limits
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (HFC-43-10mee)
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA
400 ppm, Ceiling
2-BUTOXYETHANOL (butyl "cellosolve")
PEL (OSHA) : 50 ppm, 240 mg/m3, 8 Hr. TWA, Skin
TLV (ACGIH) : 20 ppm, 8 Hr. TWA, A3
AEL * (DuPont) : 20 ppm, 8 & 12 Hr. TWA
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
6107FR DuPont Page 6
Material Safety Data Sheet
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Boiling Point : 60.9 C (141.6 F)
Vapor Pressure : 226 mm Hg @ 25 C (77 F)
Vapor Density : 8.4 (Air=1.0)
pH : Neutral
Form : Liquid
Color : Clear, colorless
Density : 1.54 g/cm3 @ 25 C (77 F)
12.8 lb/gal
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Incompatible with alkali or alkaline earth metals - powdered
Al, Zn, Be, Na, Mg, etc.
Incompatible with strong bases such as NaOH, KOH, etc.
Decomposition
Decomposes with heat. High temperatures (open flames,
glowing metal surfaces, etc.) can decompose HFC-43-10mee
forming hydrofluoric acids and possibly carbonyl halides.
HFC-43-10mee is incompatible with strong bases and can react
to form salts of hydrofluoric acid and unsaturated compounds
of unknown toxicity.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
HFC-43-10MEE:
Oral LD50: > 5,000 mg/kg in rats
Dermal ALD: > 5,000 mg/kg in rabbits
Inhalation, 4 hour LC50: 11,100 ppm in rats
Animal testing indicates that HFC-43-10mee is a slight skin
irritant and a mild eye irritant, but is not a skin
sensitizer. Single exposure to 5,000 ppm HFC-43-10mee by
6107FR DuPont Page 7
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
inhalation caused tremors. A different single exposure
study by inhalation in rats caused incoordination,
hyperactivity and prostration; pathological examination of
rats from this study revealed kidney and lung changes, and
external hair loss. Repeated exposures to 1,900 - 3,500 ppm
caused tremors or convulsions, behavioral effects, and
altered clinical chemistry. These effects were temporary.
In a different repeated exposure test the
No-Observed-Adverse-Effect-Level (NOAEL) for convulsions was
1000 ppm. Results indicate convulsions is an acute effect
of HFC-43-10mee. The 90-day No-Observed-Adverse-Effect-Level
(NOAEL) is 500 ppm. In animal testing HFC-43-10mee produced
developmental effects only at exposure levels producing
other toxic effects in the adult animal. No animal data are
available to define the carcinogenic or reproductive hazards
of HFC-43-10mee. Tests have shown that HFC-43-10mee does
not cause genetic damage in bacterial or mammalian cell
cultures. It has not produced genetic damage in on animals.
2-BUTOXYETHANOL (BUTYL "CELLOSOLVE"):
Inhalation 4 hour LC50: 450 ppm in rats
Skin absorption LD50: 566 mg/kg in rabbits
Oral LD50: 470 mg/kg in rats
"Cellosolve" is a moderate skin irritant, is a severe eye
irritant, but is untested for animal sensitization. Repeated
exposures by inhalation to approximately 100 ppm cause
destruction of red blood cells, and blood or hemoglobin in
the urine. The effects from a single exposure from
inhalation or skin contact include red blood cell
destruction. The effects of repeated ingestion include
destruction of red blood cells, hemoglobin or red blood
cells in the urine, liver and kidney weight change, effects
on liver enzymes, testicular atrophy, and reduced body
weight. Repeated applications caused skin irritation,
hematological effects and blood in the urine. Tests for
carcinogenic activity have not been performed. Butyl
"Cellosolve" does not produce genetic damage in bacterial
cultures but has not been tested in animals. Butyl
"Cellosolve" does produce developmental toxicity in rats,
rabbits and mice, but only at levels that are also
maternally toxic. Some studies showed testicular effects in
male rats and mice and reproductive and fertility effects in
mice, but only at doses that also produced other toxic
effects.
6107FR DuPont Page 8
Material Safety Data Sheet
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity:
HFC-43-10MEE:
96 hour LC50, fathead minnows: 27.2 mg/L
96 hour LC50, rainbow trout: 13.9 mg/L
48 hour LC50, Daphnia magna: 11.7 mg/L
2-BUTOXYETHANOL (BUTYL "CELLOSOLVE"):
96 hour LC50, bluegill sunfish: 1,490 mg/L
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations.
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TRANSPORTATION INFORMATION
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Shipping Information
Not regulated in transportation by DOT/IMO/IATA.
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REGULATORY INFORMATION
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U.S. Federal Regulations
TSCA Inventory Status : Listed.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No
6107FR DuPont Page 9
Material Safety Data Sheet
(REGULATORY INFORMATION - Continued)
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (CAS# 138495-42-8) is
controlled by TSCA Section 5, Significant New Use Rule
(SNUR; 40 CFR 721.5645) The approved uses are: precision and
general cleaning, carrier fluid, displacement drying,
printed circuit board cleaning, particulate removal and film
cleaning, process medium, heat transfer fluid (dielectric
and non-dielectric), and test fluid. Processors and users
of this substance must also comply with the applicable
general SNUR requirements set forth in 40 CFR 721 subpart A,
including export notification requirements if applicable (40
CFR 721.20), and the applicable record keeping requirements
set forth at 40 CFR 721.125.
LISTS:
SARA Extremely Hazardous Substance - No
CERCLA Hazardous Substance - No
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NPCA-HMIS Rating
Health :1
Flammability :0
Reactivity :1
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information
"CELLOSOLVE" is a registered trademark of Union Carbide.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : MSDS Coordinator
> : DuPont Fluoroproducts
Address : Wilmington, DE 19898
Telephone : (800) 441-7515
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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