METRA庐 BAP EIA Kit
Catalog No.: 8012
Reference No.: 981373 Revision Date: June 8, 2005
SECTION 1 鈥? Product / Preparation and Company Identification
METRA庐 BAP EIA Kit
1.1 (For In Vitro Diagnostic Use)
The Metra庐 BAP assay is an immunoassay in a microtiter strip format utilizing a monoclonal, anti-BAP
1.2
antibody coated on the strip to capture BAP in the sample. The enzyme activity of the captured BAP is
detected with a pNPP substrate.
1.3 Manufacturer: Quidel Corporation 鈥? 10165 McKellar Court 鈥? San Diego, CA 92121
Telephone No.: 1-858-552-1100 Toll Free No.: 1-800-874-1517 Fax No.: 1-858-453-4338
1.4 Emergency No.: Poison Control @ 1-800-876-4766 (USA only)
SECTION 2 鈥? Composition / Ingredients Information
2.1 Description of Components: Substrate Tablets, BAP Standards A 鈥? F, Low/High Controls, Assay Buffer,
Substrate Buffer, Coated Strips, Stop Solution, 10X Wash Buffer
2.2 Hazardous Ingredients: Dangerous solid or liquid substances present in >1% (or as required by applicable
U.S., Canadian and E.U. regulations):
Classification :
Chemical Kit %
CAS# EINECS Name Component Weight US OSHA WHMIS EU Risk Phrases
4702
Sodium Hydroxide
1310-73-2 215-185-5 1.5% Corrosive Corrosive Xi R36/38
(Stop)
4404
2-amino-2-methyl- R36/38,
124-68-5 204-709-8 35% Irritant Corrosive Xi
1-propanol R52/53
(Substrate)
**See Section 15 and Section 16 鈥? Regulatory Information for additional information on hazard classifications.
SECTION 3 鈥? Hazard Identification
Emergency Overview: As part of good industrial and personal hygiene and safety procedure, avoid all
unnecessary exposure to the chemical components of this kit and ensure prompt removal from skin, eyes, and
clothing.
3.1 Some components of this kit are considered as hazardous or dangerous preparations as defined by the
Occupational Safety and Health Administration (OSHA), the Canadian Workplace Materials Information
System (WHMIS), and the European Union (EU) Directives 1999/45/EC and 67/548/EEC. No significant
health effects are anticipated from routine use.
3.2 Contact with Stop Solution (#4702) or Substrate Buffer (#4404) to the eyes and/or skin may cause irritation
upon a single exposure. Avoid prolonged contact.
3.3 This kit contains material of animal origin and should be considered as potentially capable of transmitting
infectious diseases.
Page 1 of 10
METRA庐 BAP EIA Kit
3.4 All patient samples, contaminated test strips, and fluids should be handled as potentially infectious. Follow
Universal Precautions as necessary.
3.5 Warning Properties:
Chemical Name Kit Component Degree Description
Sodium Hydroxide 4702 (Stop) Poor Sodium Hydroxide is odorless.
2-amino-2-methyl-1-
4404 (Substrate) Poor Solution is odorless.
propanol
SECTION 4 鈥? First Aid Measures
Special Instructions:
4.1 Inhalation: Inhalation of any component in this kit is unlikely. If a component of this kit is inhaled and
causes discomfort, move exposed individual to fresh air. Seek medical attention if breathing
is difficult or symptoms persist.
4.2 Eye Contact: If a component of this kit enters the eyes and causes discomfort, wash eyes gently under
potable running water for 15 minutes or longer, making sure that the eyelids are held open. If
pain or irritation occurs, obtain medical attention.
4.3 Skin Contact: If a component of this kit contacts the skin and causes discomfort, remove any contaminated
clothing. Wash affected area with plenty of soap and water. If pain or irritation occurs, obtain
medical attention.
4.4 Ingestion: If a component of this kit is ingested, wash mouth out with water. If irritation or discomfort
occurs, obtain medical attention.
SECTION 5 鈥? Fire Fighting Measures
5.1 Extinguishing Media: For small fires, use dry chemical, carbon dioxide, or alcohol-resistant foam.
5.2 Special Fire Fighting Procedures: This material will not significantly contribute to the intensity of a fire. Use
extinguishing material suitable to the surrounding fire. Utilize proper personal protective equipment when
responding to any fire. Incipient fire responders should wear eye protection. Structural firefighters must wear
Self-Contained Breathing Apparatus and full protective equipment. Move containers from fire area if it can be
done without risk to personnel. If possible, prevent runoff water from entering storm drains, bodies of water, or
other environmentally sensitive areas.
5.3 Unusual Fire and Explosion Hazards: When involved in a fire, this material can decompose and produce
irritating fumes and toxic gases (e.g., Carbon monoxide, Carbon dioxide).
Explosion Sensitivity to Mechanical Impact: Not sensitive under normal conditions.
Explosion Sensitivity to Static Discharge: Not sensitive under normal conditions.
5.4 Additional Considerations (Stop Solution and Substrate Buffer):
5.4.1 Flash Point Non Combustible
5.4.2 Auto-ignition Temperature Not Applicable
5.4.3 Upper / Lower Explosion Limit Not Applicable
Page 2 of 10
METRA庐 BAP EIA Kit
5.5 NFPA Ratings:
Stop Solution #4702 Substrate Buffer #4404
1.5% Sodium Hydroxide 35% 2-amino-2-methyl-1-propanol
Flammability
Flammability
0
0
1 0
1 0
Health Reactivity
Health Reactivity
Other Hazards Other Hazards
** Only trained and competent personnel shall attempt to extinguish a fire. Contact emergency response
personnel as required. Be cautious of surrounding materials that may react with the extinguishing media.
SECTION 6 鈥? Accidental Release Measures
6.1 Personal Precautions: This kit contains materials of biological origin. Avoid personal contact. Use
Universal Precautions during clean-up procedures.
6.2 Environmental Precautions: No environmental hazard is anticipated provided that the material is handled
and disposed of with due care. Contain spill to prevent migration.
6.3 Spill and Leak Procedures: Large spills of this product are unlikely. Personnel who have received basic
chemical safety training can generally handle small-scale releases, such as
1 container of this product. Utilize safety glasses, nitrile gloves, and lab
coat/apron when responding to spills involving the components of this kit.
Absorb liquid and place in container suitable for disposal. Dispose of in
accordance with applicable U.S. Federal, State, or local procedures or
appropriate standards of Canada (see Section 13, Disposal Considerations).
SECTION 7 鈥? Handling and Storage
7.1 Handling: As with all chemicals, avoid getting this product ON YOU or IN YOU. Wash thoroughly after
using this product. Do not eat or drink while using this kit. This kit should be handled only by
qualified clinical or laboratory employees trained on the use of this kit and who are familiar
with the potential hazards.
This kit should be handled as though capable of transmitting infectious diseases. Universal
Precautions should be followed when using this kit.
Professional use only 鈥? Not for use by general public
7.2 Storage: Keep away from incompatible materials (Section 10). To maintain efficacy, store according
to the package insert instructions.
7.3 Specific Use: For In Vitro Diagnostic Use.
Page 3 of 10
METRA庐 BAP EIA Kit
SECTION 8 鈥? Exposure Controls and Personal Protection
8.1 Exposure Limits:
CAS# Chemical Name OSHA (PEL) ACGIH (TLV) MAK
3 3
2 mg/m3
1310-73-2 Sodium Hydroxide 2 mg/m 2 mg/m (Ceiling)
124-68-5 2-amino-2-methyl-1-propanol None Established None Established None Established
8.2 Occupational Exposure Controls:
8.2.1 Engineering Controls:
No special engineering controls are required when working with this kit. Use with adequate ventilation
to ensure exposure levels are maintained below the limits provided above.
8.2.2 Personal Protective Equipment (PPE):
Respiratory
Protection: None needed under normal conditions of use.
Eye Contact: Safety glasses are recommended to prevent eye contact.
Hand Contact: Impervious gloves (nitrile or equivalent) should be worn to prevent hand contact.
Skin Contact: Lab Coat or similar garment should be worn.
8.2.3 Environmental Controls: No special environmental controls are required.
SECTION 9 鈥? Physical and Chemical Properties
Stop Solution: Substrate Buffer:
Characteristic
1.5% Sodium Hydroxide 35% 2-amino-2-methyl-1-propanol
100 165
Boiling Point (掳C)
0 31
Melting Point (掳C)
1.3
Specific Gravity (H2O = 1) 0.934
14
Vapor Pressure (mm Hg) at 20 C Not available
N/A
Vapor Density (AIR = 1) 3.04
<1
Evaporation Rate (Ether = 1) <1
13
pH: 10.4
Complete
Solubility in Water: Soluble
Clear colorless liquid with no odor
Appearance and Odor: No odor
Page 4 of 10
METRA庐 BAP EIA Kit
SECTION 10 鈥? Stability and Reactivity
Stop Solution: Substrate Buffer:
Characteristic
1.5% Sodium Hydroxide 35% 2-amino-2-methyl-1-propanol
Stable Stable
Stability
Incompatible materials Incompatible materials
Conditions to Avoid
Materials to avoid Strong oxidizing agents; Strong oxidizing agents;
Strong acids Strong acids
(Incompatibilities)
Thermal decomposition may release
Hazardous Decomposition or Thermal decomposition may release toxic
irritating fumes or toxic gases (e.g., Carbon
Byproducts fumes of sodium oxide
monoxide, Carbon dioxide).
Will not occur Will not occur
Hazardous Polymerization
SECTION 11 鈥? Toxicological Information
11.1 Toxicity Data for Hazardous Ingredients: There are currently no toxicity data available for the components of
this kit; the following toxicology information is available for raw materials present in greater than 1%
concentration.
The following data are available for Sodium hydroxide:
Eye effects-Monkey 1%/24H Severe irritation effects
Skin-Rabbit, adult 500 mg/24H Severe irritation effects
Eye effects-Rabbit, adult 4 g Mild irritation effects
Eye effects-Rabbit, adult 1% Severe irritation effects
Eye effects-Rabbit, adult 50 mg/24H Severe irritation effects
Eye effects-Rabbit, adult 1mg/24H Severe irritation effects
Eye effects-Rabbit, adult 100 mg rns Severe irritation effects
Cytogenetic Analysis-grasshopper-Parenteral 20 mg
Intraperitoneal-Mouse LD50: 40 mg/kg
Oral-Rabbit, adult LDLo: 500 mg/kg
The following data are available for 2-amino-2-methyl-1-propanol:
Oral-Rat LD50: 2900 mg/kg
Oral-Mouse LD50: 2150 mg/kg
Oral-Rabbit, adult LDLo: 1 g/kg
11.2 Primary Routes of Exposure:
Overexposures to components within this kit are not expected. Common routes of exposure may
include ingestion and eye/skin contact. Specific paths of concern for potentially infectious materials are skin
puncture, contact with broken skin, contact with mucous membranes and inhalation of aerosolized material.
Page 5 of 10
METRA庐 BAP EIA Kit
11.3 Potential Effects of Acute Overexposure, By Route Of Exposure:
This kit contains material of animal origin and should be considered as potentially capable of transmitting
infectious diseases.
INHALATION: Vapors, mists, sprays, or dusts of this product can cause irritation to the respiratory tract.
CONTACT WITH
SKIN or EYES: Contact can cause eye or skin irritation.
SKIN ABSORPTION: No component of this product is reported to be absorbed through intact skin.
INGESTION: If the product is swallowed, irritation of the mouth, throat, and other tissues of the
gastro-intestinal system can occur.
INJECTION: Accidental injection of this product can cause burning, reddening, and swelling in
addition to the wound. Symptoms of such exposure can include those described under
鈥淚nhalation,鈥? 鈥淐ontact with Skin or Eyes,鈥? and 鈥淚ngestion.鈥?
11.4 Potential Effects of Chronic Exposure:
Long-term skin or eye contact can result in dermatitis or eye irritation.
11.5 Symptoms of Overexposure:
Symptoms of overexposure may include: eye, skin, nose, and throat irritation, headache, nausea and
vomiting, and burns to contacted areas. Symptoms may be delayed for several hours after exposure.
11.6 Medical Exposure Aggravated by Exposure:
Persons with pre-existing skin disorders; eye problems or impaired respiratory system function can be more
susceptible to health effects associated with overexposures to this product.
11.7 Carcinogenicity:
The ingredients in this kit are not listed as carcinogens by any of the following: ACGIH, IARC, NTP, or OSHA.
SECTION 12 鈥? Ecological Information
12.1 Ecotoxicity:
No adverse effects on the environment are expected from the components of this kit.
12.2. Mobility:
Mobility data are not available for the components of this product.
12.3. Persistence and Degradability:
There is no persistence or degradation data for any component of this product at this time.
12.4. Bioaccumulative Potential:
There is limited potential for the components within this kit to accumulate in plant or animal systems.
SECTION 13 鈥? Disposal Considerations
Dispose of waste materials, unused components and contaminated packaging in compliance with federal, state and
local regulations. If unsure of the applicable requirements, contact the authorities for information.
Page 6 of 10
METRA庐 BAP EIA Kit
SECTION 14 鈥? Transport Information
14.1 U.S. Transportation:
This product is regulated per 49 CFR 172.101, the U.S. department of transportation:
PROPER SHIPPING NAME: Sodium Hydroxide Solution
HAZARD CLASS NUMBER and DESCRIPTION: Class 8, Corrosive
UN IDENTIFICATION NUMBER: UN 1824
DOT LABEL(S) REQUIRED: Class 8
PACKAGING GROUP: II
NORTH AMERICAN RESPONSE GUIDEBOOK NUMBER (2000): 154
MARINE POLLUTANT: No component is designated as a DOT Marine Pollutant.
Small quantities of Class 8 materials are not subject to additional shipping requirements, provided that the
requirements of 49 CFR 173.4, 鈥淪mall quantity exceptions鈥? are met. The maximum quantity of material per
inner receptacle is limited to 30 ml, the packaging must meet the specifications in 49 CFR 173.4, the gross
mass of the completed must not exceed 29 kg and the shipper must certify conformance with that section by
marking the outside of the package with the statement 鈥淭his package conforms to 49 CFR 173.4.鈥?
14.2 Canadian Transportation:
The above-listed DOT basic description applies to this product under the regulations of Transport Canada.
14.3 International Air Transportation:
This product is regulated per International Air Transportation Association (IATA) Dangerous Goods
Regulations:
PROPER SHIPPING NAME: Sodium Hydroxide Solution
HAZARD CLASS NUMBER and DESCRIPTION: Class 8, Corrosive
UN IDENTIFICATION NUMBER: UN 1824
DOT LABEL(S) REQUIRED: Class 8
PACKAGING GROUP: II
Packing Instruction (Limited Quantity) 809 (Y809)
Small quantities of Class 8 materials are not subject to additional shipping requirements, provided that the
requirements of Section 2.7, 鈥淒angerous Goods in Excepted Quantities鈥? are met. The maximum quantity of
material per inner package must be less than 30 mL, the total net quantity of Dangerous Goods in each outer
package is limited to 500 g or 500 mL, and each package containing Dangerous Goods in Excepted
Quantities must be labeled with the 鈥淓xcepted Quantities Label (2.7.6)鈥? as shown in Figure 2.7.B of the 2004
IATA Dangerous Goods Regulations.
Page 7 of 10
METRA庐 BAP EIA Kit
SECTION 15 鈥? Regulatory Information
15.1 U.S. Federal and State Regulations:
Sodium Hydroxide 2-amino-2-methyl-1-propanol
40 CFR 355.30/355.40 - SECTION 302 Not Listed Not Listed
40 CFR 302.4 - SECTION 304 RQ = 1000 lbs. Not Listed
40 CFR 372.65 - SECTION 313 Not Listed Not Listed
U.S. SARA SECTION 311/312 FOR PRODUCT: Acute health effects; chronic health effects.
U.S. TSCA INVENTORY STATUS: The components of this product are listed on the TSCA Inventory.
OTHER U.S. FEDERAL REGULATIONS: Not applicable.
CALIFORNIA SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT (PROPOSITION 65):
This material is not found on either the Proposition 65 Carcinogen List or the Adverse Reproductive Effects List.
15.2 Label Information:
ANSI Z129.1 Stop Solution Substrate Buffer Kit Package
CAUTION:
CAUTION: Kit components may be
Corrosive. Harmful CAUTION: Eye and
Labeling: corrosive, harmful if swallowed or eye and
if swallowed, eye skin Irritant.
skin irritants.
and skin irritant.
Do not swallow or take internally. Do not
Do not get in eyes, get in eyes, on skin, or on clothing. Wash
Do not swallow or
on skin, or on thoroughly after handling. This kit contains
Label take internally. Do
material of animal origin and should be
clothing. Wash
Precautions: not get in eyes, on
thoroughly after considered as potentially capable of
skin, or on clothing.
handling. transmitting infectious diseases. Follow
package insert instructions for use.
ENVIRONMENTAL HAZARDS: Do not discharge effluent containing this product into streams, ponds,
estuaries, oceans or other waters unless in accordance with the requirements of a National Pollutant Discharge
Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge.
Do not discharge effluent containing this product to sewer systems without previously notifying the local sewage
treatment plant authority. For guidance, contact your State Water Board or Regional Office of the EPA.
15.3 Canadian Regulations:
CANADIAN DSL/NDSL INVENTORY STATUS:
The components of this product are listed on the DSL Inventory.
CANADIAN WHMIS SYMBOLS:
E Corrosive Materials
Page 8 of 10
METRA庐 BAP EIA Kit
15.4 HMIS Ratings (See Page 16 for Definition of Ratings):
Substrate Buffer 鈥? 35% 2-amino-2-methyl-1-
Stop Solution 鈥? 1.5% Sodium Hydroxide
propanol
Health 2* Health 1*
Flammability 0 Flammability 0
Physical Hazard 0 Physical Hazard 0
Protective Equipment Protective Equipment C
C
15.5 EU Labeling Classification:
Risk Phrases:
Classification: R36/38: Irritating to eyes and skin.
Stop Solution Safety Phrases:
1.5% Sodium Hydroxide
S2: Keep out of the reach of children.
S26: In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S37/39: Wear suitable gloves and eye/face protection.
Xi Irritant S45: In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
Classification: Risk Phrases (for 2-amino-2-methyl-1-propanol):
R36/38: Irritating to eyes and skin.
Substrate Buffer
R52/53: Harmful to aquatic organisms, may cause long-term adverse
35% 2-amino-2-methyl-1-
effects in the aquatic environment.
propanol
Safety Phrases:
S2: Keep out of the reach of children.
S61: Avoid release to the environment. Refer to special
instructions/Safety data sheets.
Xi Irritant
SECTION 16 鈥? Other Information
PREPARED BY: QUIDEL CORPORATION
10165 McKellar Court
San Diego, CA 92121
(800)-874-1517
DATE OF PRINTING: July 22, 2005
Quidel Corporation provides the information contained herein in good faith but makes no representation as to its
comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary
handling of the materials contained in this kit by a properly trained person using this kit. Quidel Corporation shall
not be held liable for any damage resulting from handling or use.
Page 9 of 10
METRA庐 BAP EIA Kit
DEFINITIONS OF TERMS
A large number of abbreviations and acronyms appear on a MSDS. Some of these, which are commonly used, include the following:
CAS #: This is the Chemical Abstract Service Number that uniquely volume, that will explode or ignite in the presence of an ignition
identifies each compound.ACGIH - American Conference of source. UEL - the highest percent of vapor in air, by volume, that will
explode or ignite in the presence of an ignition source.
Governmental Industrial Hygienists, a professional association which
establishes exposure limits.
TOXICOLOGICAL INFORMATION:
TLV - Threshold Limit Value - an airborne concentration of a Possible health hazards as derived from human data, animal
substance that represents conditions under which it is generally studies, or from the results of studies with similar compounds are
believed that nearly all workers can be repeatedly exposed without presented. Definitions of some terms used in this section are: LD50 -
adverse effect. The duration must be considered, including the 8- Lethal Dose (solids & liquids) which kills 50% of the exposed
hour Time Weighted Average (TWA), the 15-minute Short Term animals; LC50 - Lethal Concentration (gases) which kills 50% of the
Exposure Limit, and the instantaneous Ceiling Level (C). Skin exposed animals; ppm concentration expressed in parts of material
3
absorption effects must also be considered. per million parts of air or water; mg/m concentration expressed in
OSHA - U.S. Occupational Safety and Health Administration. weight of substance per volume of air; mg/kg quantity of material, by
PEL - Permissible Exposure Limit - This exposure value means weight, administered to a test subject, based on their body weight in
exactly the same as a TLV, except that it is enforceable by OSHA. kg. Other measures of toxicity include TDLo, the lowest dose to
The OSHA Permissible Exposure Limits are based in the 1989 PELs cause a symptom and TCLo the lowest concentration to cause a
and the June, 1993 Air Contaminants Rule (Federal Register: 58: symptom; TDo, LDLo, LDo, TC, TCo, LCLo, and LCo, the lowest
35338-35351 and 58: 40191). Both the current PELs and the dose (or concentration) to cause lethal or toxic effects. BEI -
vacated PELs are indicated. The phrase, 鈥淰acated 1989 PEL,鈥? is Biological Exposure Indices, represent the levels of determinants
placed next to the PEL that was vacated by Court Order. which are most likely to be observed in specimens collected from a
IDLH - Immediately Dangerous to Life and Health - This level healthy worker who has been exposed to chemicals to the same
represents a concentration from which one can escape within 30- extent as a worker with inhalation exposure to the TLV. Ecological
Information: EC is the effect concentration in water.
minutes without suffering escape-preventing or permanent injury.
The DFG - MAK is the Republic of Germany鈥檚 Maximum Exposure Data from several sources are used to evaluate the cancer-causing
Level, similar to the U.S. PEL. NIOSH is the National Institute of potential of the material. The sources and ratings are: IARC - the
Occupational Safety and Health, which is the research arm of the
International Agency for Research on Cancer; 1 = Carcinogenic to
U.S. Occupational Safety and Health Administration (OSHA).
humans, 2A, 2B = Probably carcinogenic to humans, 3 =
NIOSH issues exposure guidelines called Recommended Exposure Unclassifiable as to carcinogenicity in humans, and 4 = Probably not
Levels (RELs). When no exposure guidelines are established, an
carcinogenic to humans. NTP - the National Toxicology Program; K
entry of NE is made for reference.
=Known to be a human carcinogen, and R = Reasonably anticipated
HAZARD RATINGS: to be a human carcinogen. RTECS - the Registry of Toxic Effects of
HAZARDOUS MATERIALS IDENTIFICATION SYSTEM: Health Chemical Substances. OSHA - Occupational Safety and Health
Hazard: 0 (minimal acute or chronic exposure hazard); 1 (slight Administration and CAL/OSHA - California鈥檚 subunit of the
acute or chronic exposure hazard); 2 (moderate acute or significant Occupational Safety and Health Administration; Ca = Carcinogen
chronic exposure hazard); 3 (severe acute exposure hazard; defined with no further categorization. ACGIH 鈥? American
onetime overexposure can cause permanent injury and can be fatal); Conference of Governmental Industrial Hygienists; A1 = Confirmed
4 (extreme acute exposure hazard; onetime overexposure can be human carcinogen, A2 = Suspected human carcinogen, A3 =
fatal). Flammability Hazard: 0 (minimal hazard); 1 (materials that Confirmed animal carcinogen with unknown relevance to humans,
require substantial pre-heating before burning); 2 (combustible liquid A4 = Not classifiable as a human carcinogen, and A5 = Not
suspected as a human carcinogen. NIOSH 鈥? U.S. National Institute
or solids; liquids with a flash point of 38-93掳C [100-200掳F]); 3 (Class
for Occupational Safety and Health; Ca = Potential occupational
IB and IC flammable liquids with flash points below 38掳C [100掳F]); 4
carcinogen, with no further categorization. EPA 鈥? U.S.
(Class IA flammable liquids with flash points below 23掳C [73掳F] and
Environmental Protection Agency; A = Human carcinogen, B =
boiling points below 38掳C [100掳F]). Reactivity Hazard: 0 (normally
Probable human carcinogen, C = Possible human carcinogen, D =
stable); 1 (material that can become unstable at elevated
Not classifiable as to human carcinogenicity, E = Evidence of Non-
temperatures or which can react slightly with water); 2 (materials that
carcinogenicity for humans, K = Known human carcinogen, L =
are unstable but do not detonate or which can react violently with
Likely to produce cancer in humans, CBD = Cannot be determined,
water); 3 (materials that can detonate when initiated or which can
NL = Not likely to be carcinogenic in humans, and I = Data are
react explosively with water); 4 (materials that can detonate at
inadequate for an assessment of human carcinogenic potential.
normal temperatures or pressures).
NATIONAL FIRE PROTECTION ASSOCIATION: Health Hazard: 0 REGULATORY INFORMATION:
(material that on exposure under fire conditions would offer no This section explains the impact of various laws and regulations on
hazard beyond that of ordinary combustible materials); 1 (materials the material. EPA is the U.S. Environmental Protection Agency.
that on exposure under fire conditions could cause irritation or minor WHMIS is the Canadian Workplace Hazardous Materials Information
residual injury); 2 (materials that on intense or continued exposure System. DOT and TC are the U.S. Department of Transportation
under fire conditions could cause temporary incapacitation or and the Transport Canada, respectively. Superfund Amendments
possible residual injury); 3 (materials that can on short exposure and Reauthorization Act (SARA); the Canadian Domestic/Non-
could cause serious temporary or residual injury); 4 (materials that Domestic Substances List (DSL/NDSL); the U.S. Toxic Substance
under very short exposure could cause death or major residual Control Act (TSCA); Marine Pollutant status according to the DOT;
injury). Flammability Hazard and Reactivity Hazard: Refer to the Comprehensive Environmental Response, Compensation, and
definitions for 鈥淗azardous Materials Identification System鈥?. Liability Act (CERCLA or Superfund); and various state regulations.
FLAMMABILITY LIMITS IN AIR: This section also includes information on the precautionary warnings
Much of the information related to fire and explosion is derived from that appear on a material鈥檚 industrial package label.
the National Fire Protection Association (NFPA). Flash Point -
Minimum temperature at which a liquid gives off sufficient vapors to
form an ignitable mixture with air. Autoignition Temperature: The
minimum temperature required to initiate combustion in air with no
other source of ignition. LEL - the lowest percent of vapor in air, by
Page 10 of 10 0115RA0305D-1 (07/05)
|