EMS CATALOG NO: 11700
EMS PRODUCT: Tris, Crystal
DATE: 04/08/99
PAGE NUMBER: One of 4
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
321 MORRIS ROAD
P.O. BOX 251
FORT WASHINGTON, PA 19034 24 HOUR EMERGENCY PHONE NUMBER
(215) 646-1566 CHEMTREC: (800) 424-9300
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FOR PRODUCT AND SALES INFORMATION
_________________________________________________________________
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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PRODUCT NAME: Tris Free Base, Ultra Pure
MOLECULAR FORM: C4H11N1O3
CAS #: 77-86-1
SYNONYMS:
Addex-Tham*2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol*2-Amino
-2(Hydroxymethly)-1,3-Propanediol*2-Amino-2-Methylol-1,3-
Propanediod*Aminotrimethylolmethane*Aminotris(Hydroxymethyl)
Methane*Methylamine, 1,1,1-Tris(Hydroxymethyl)-*Pehanorm*
Talatrol*Tham*Tham-E*Tham Set*Trimethylolaminomethane*
Trisamine*Tris-Amino*Trisaminol*Tris Buffer*Tris-Hydroxymethyl
-Aminomethan (GER)8Trometamol*Trometamole*Tris
Hydroxymethylaminomethane*Tris(Hydroxymethyl)Methanamine*
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Tris(Hydroxymethyl)Methylamine*Trispuffer*Tris-Steril*
Tromethamine*Tromethane*Tromethanmin*Tutofusin Tris
OSHA REGULATED COMPONENTS: No Hazardous Components
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TOXICITY DATA
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RTECS NO.
RTECS NAME: 1,3-Propanediol, 2-Amino-2-(Hydroxymethyl)-
TOXICITY DATA:
Orl-Rat LD50: 5900 mg/kg BCFAAI 110,653,71
Ivn-Mus LD50: 1210 mg/kg ABMGAJ 17,217,66
REGULATIONS, STANDARDS, AND REVIEWS:
NOHS 1974: HZD 81165; NIS 4; TNF 850;.NOS 6: TNE 7274
NOES 1983: HZD 81165000; TNG 9; NIS 2296; NOS 22; TNE 40897;
TFE 30773
TARGET ORGAN DATA: No data available.
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HEALTH HAZARDS DATA
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HEALTH HAZARDS ACUTE/CHRONIC:
Harmful if ingested, inhaled, or absorbed through the skin.
Causes eye and skin irritation.
Material is irritating to mucous membranes and upper respiratory
tract.
SIGNS AND SYMPTOMS OF EXPOSURE: No data available.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: No data available.
EMERGENCY / FIRST AID PROCEDURES:
In case of contact, wash skin with soap and copious amounts of water
for at least 15 minutes.
In case of contact, flush eyes with copious amounts of water for at
least 15 minutes.
If swallowed, wash out mouth with water provided person is conscious.
If inhaled, remove to fresh air. If not breathing give artificial
respiration. If breathing is difficult give oxygen.
In all cases, call a physician.
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FIRE AND EXPLOSION HAZARD DATA
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EXTINGUISHING MEDIA:
Water spray, carbon dioxide, dry chemical powder, alcohol or
polymer foam
SPECIAL FIRE FIGHTING PROCEDURES:
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eye.
UNUSUAL FIRE AND EXPLOSION HAZARDS: Emits toxic fumes under fire con-
ditions.
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PHYSICAL / CHEMICAL CHARACTERISTICS
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BOILING POINT: 219-220oC
MELTING POINT: 1678-169oC
APPEARANCE/ODOR: White crystaline powder
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REACTIVITY DATA
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CONDITIONS TO AVOID: No data available.
INCOMPATIBILITY: Bases, oxidizing agents
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PROCEDURES FOR LEAKS AND/OR SPILLS
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STEPS TO BE TAKEN IN CASE OF A SPILL:
Wear respirator, chemical safety goggles, rubber boots and heavy
rubber gloves.
Avoid raising dust.
Sweep up, place in a bag and hold for waste disposal.
Ventilate area and wash spill site after material pickup is
complete.
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PROCEDURE FOR WASTE DISPOSAL:
(Observe all Federal, State, and local regulations)
The material should be ignited in the presence of sodium
carbonate and slaked lime (calcium hydroxide). The substance
should be mixed with vermiculite and the dry caustics wrapped in
paper and burned in a chemical incinerator equipped with an after
burner and scrubber.
STORAGE AND HANDLING PRECAUTIONS:
Do not breathe dust.
Avoid contact with eyes, skin and clothing.
Avoid prolonged or repeated exposure.
Wash thoroughly after handling.
Irritant.
Keep tightly closed.
PRIMARY SHIPPING CONDITION: Ambient temperature.
RECOMMENDED STORAGE CONDITION: Room temperature 15 to 30oC.
LABEL PRECAUTIONARY STATEMENTS: No data available.
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EMPLOYEE PERSONAL PROTECTION
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RESPIRATORY PROTECTION: NIOSH/MSHA-Approved respirator
VENTILATION: Mechanical exhaust required
PROTECTIVE GLOVES: Chemical-resistant gloves
EYE PROTECTION: Chemical Safety goggles
OTHER PROTECTIVE EQUIPMENT: Safety shower and eye bath
THE INFORMATION IS THIS MATERIAL SAFETY DATA SHEET MEET THE
REQUIREMENTS OF THE UNITED STATES OSHA HAZARD COMMUNICATION STANDARD
(29 cfr 1910.1200).
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