EMS CAT AL OG NO: 11772-10
EMS PR ODUCT : Phosphat e B uf f er ed S aline
DAT E: Apr il 18, 2001
PAGE NUMB ER : One of 7
MAT ER I AL S AFET Y DAT A S HEET
T he information contained herein is based on data considered accurate. However,
no warranty is expressed or implied regarding the accuracy of these data or the
results to be obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for personal injury or
property damage to vendees, users or third parties caused by the material. Such
vendees or users assume all risks associated with the use of the material.
EL ECT R ON MI CR OS COPY S CI ENCES
321 MORRI S ROAD * P.O. BOX 251 email: sgkcck@aol.com
P.O. BOX 251 WEB: www.emsdiasum.com
FORT WASHI NG ON, PA 19034
T
215-646-1566 / fax 215-646-8931
24 HOUR EMER GENCY PHONE NUMB ER CHEMT R EC: (800) 424-9300
FOR PR ODUCT AND S AL ES I NFOR MAT I ON
CONT AC ELEC RON MI C
T T ROSCOPY SC ENC OFFI C ABOVE.
I ES E
PR ODUCT I DENT I FI CAT I ON
COMMON NAME: Phosphate Buffered Saline
COMMER CI AL NAME(S ): Not available.
S YNONYM: Not available.
CHEMI CAL NAME: Phosphate Buffered Saline
CHEMI CAL FAMI L Y: C hloride salt. (Salt.)
CHEMI CAL FOR MUL A: Not applicable
CAS # : Mixture
R T ECS : Not applicable.
T S CA: T S CA 8(b) invent or y: Water, Sodium Chloride; Potassium Chloride, Sodium
Phosphate dibasic
CI # : Not applicable.
COMPOS I T I ON AND I NFOR MAT I ON ON I NGR EDI ENT S
NAME: Water
CAS # : 7732-18-5
T W A(mg/ m3):
S T EL (mg/ m3):
% B Y W EI GHT : 97
NAME: Sodium C hloride
CAS # : 7647-14-5
T W A(mg/ m3):
S T EL (mg/ m3):
% B Y W EI GHT : 1
NAME: Potassium C hloride
CAS # : 7447-40-7
T W A(mg/ m3):
S T EL (mg/ m3):
% B Y W EI GHT : 1
NAME: Sodium Phosphate, dibasic
CAS # : 7758-79-4
T W A(mg/ m3):
S T EL (mg/ m3):
% B Y W EI GHT : 1
T OXI COL OGI CAL DAT A ON I NGR EDI ENT S :
SODI UM CHLORI DE
OR AL (L D50): Acute: 3000 mg/kg [Rat].
POT ASSI UM CHLORI DE
OR AL (L D50): Acute: 2500 mg/kg [Guinea pig]. 2600 mg/kg [Rat]. 2715 mg/kg [Mouse].
SODI UM PHOSPHAT E, DI BASI C
(L D50): Not available.
(L C50): Not available.
HAZ AR DS I DENT I FI CAT I ON
POT ENT I AL ACUT E HEAL T H EFFECT S : Hazardous in case of eye contact (irritant), of
inhalation. Slightly hazardous in case of skin contact (irritant), of ingestion. Non-
corrosive for skin. Non-permeator by skin.
POT ENT I AL CHR ONI C HEAL T H EFFECT S : Non-C orrosive for skin. Non-irritant for
skin. Non -sensitizer for skin. Non-permeator by skin. Non-irritating to the eyes. Non-
hazardous in case of ingestion. Non-hazardous in case of inhalation.
Catalog # 11772-10 Page 2 of 7
Phosphate Buffered Saline
CAR CI NOGENI C EFFECT S : Not available.
MUT AGENI C EFFECT S : Not available.
T ER AT OGENI C EFFECT S : Not available.
DEVEL OPMENT AL T OXI CI T Y: C lassified Reproductive system/toxin/female.
Reproductive system/toxin/male [SUSPEC ED] [Phosphate Buffered Saline].
T
T his substance may be toxic to blood, the reproductive system , upper respiratory tract,
central nervous system (CNS). Repeated or prolonged exposure to the substance can
produce target organs damage.
FI R S T AI D MEAS UR ES
EYE CONT ACT : C heck for and remove any contact lenses. I n case of contact,
immediately flush eyes with plenty of water for at least 15 minutes. C water may be
old
used. G medical attention.
et
S KI N CONT ACT : Wash with soap and water. C over the irritated skin with an
emollient. G medical attention if irritation develops. C water may be used.
et old
S ER I OUS S KI N CONT ACT : Not available.
I NHAL AT I ON: I f inhaled, remove to fresh air. I f not breathing, give artificial
respiration. I f breathing is difficult, give oxygen. G medical attention.
et
S ER I OUS I NHAL AT I ON: Not available.
I NGES T I ON: Do NOT induce vomiting unless directed to do so by medical personnel.
Never give anything by mouth to an unconscious person. Loosen tight clothing such as
a collar, tie, belt or waistband. G medical attention if systems appear.
et
S ER I OUS I NGES T I ON: Not available.
FI R E AND EXPL OS I ON DAT A
FL AMMAB I L I T Y OF T HE PR ODUCT : Non-Flammable.
AUT O-I GNI T I ON T EMPER AT UR E: Not applicable.
FL AS H POI NT S : Not applicable.
FL AMMAB L E L I MI T S : Not applicable.
PR ODUCT S OF COMB US T I ON: Not available.
FI R E HAZ AR DS I N PR ES ENCE OF VAR I OUS S UB S T ANCES : Not applicable.
EXPL OS I ON HAZ AR DS I N PR ES ENCE OF VAR I OUS S UB S T ANCES :
R I S KS OF EXPL OS I ON OF T HE PR ODUCT I N PR ES ENCE OF MECHANI CAL
I MPACT : Not available.
R I S KS OF EXPL OS I ON OF T HE PR ODUCT I N PR ES ENCE OF S T AT I C
DI S CHAR GE: Not available.
Catalog # 11772-10 Page 3 of 7
Phosphate Buffered Saline
FI R E FI GHT I NG MEDI A AND I NS T R UCT I ONS : Not applicable.
S PECI AL R EMAR KS ON FI R E HAZ AR DS : Not available.
S PECI AL R EMAR KS ON EXPL OS I ON HAZ AR DS : Not available.
ACCI DENT AL R EL EAS E MEAS UR ES
S MAL L S PI L L : Dilute with water and mop up, or absorb with an inert dry material and
place in an appropriate waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local regional authority
requirements.
L AR GE S PI L L : Absorb with an inert material and put the spilled material in an
appropriate waste disposal.
HANDL I NG AND S T OR AGE
PR ECAUT I ONS : Keep locked up. Do not ingest. Do not breathe gas/fumes/
vapor/spray. Avoid contact with eyes. Wear suitable protective clothing. I n case of
insufficient ventilation, wear suitable respiratory equipment. I f ingested, seek medical
advice immediately and show the container or the label. Keep away from incompatibles
such as oxidizing agents, moisture.
S T OR AGE: Keep container tightly closed. Keep container in a cool, well-ventilated
area.
EXPOS UR E CONT R OL S / PER S ONAL PR OT ECT I ON
ENGI NEER I NG CONT R OL S : Provide exhaust ventilation or other engineering controls
to keep the airborne concentrations of vapors below their respective threshold limit
value.
PER S ONAL PR OT ECT I ON: Splash goggles. Lab coat. Vapor respirator. Be sure to
use an approved/certified respirator or equivalent.
PER S ONAL PR OT ECT I ON I N CAS E OF A L AR GE S PI L L : Splash goggles. Full suit.
Vapor respirator. Boots. G loves. A self contained breathing apparatus should be used
to avoid inhalation of the product. Suggested protective clothing might not be
sufficient; consult a specialist BEFORE handling this product.
EXPOS UR E L I MI T S : Not available.
PHYS I CAL AND CHEMI CAL PR OPER T I ES
PHYS I CAL S T AT E AND APPEAR ANCE: Liquid.
ODOR : Not available.
T AS T E:Not available.
Catalog # 11772-10 Page 4 of 7
Phosphate Buffered Saline
COL OR : Not available.
MOL ECUL AR W EI GHT : Not applicable.
pH (1% S OL N/ W AT ER ): Neutral.
B OI L I NG POI NT : T he lowest known value is 100oC (212oF)
MEL T I NG POI NT : Not available.
CR I T I CAL T EMPER AT UR E: Not available.
S PECI FI C GR AVI T Y: Weighted average: 1.01 (Water= 1).
VAPOR PR ES S UR E: T he highest known value is 2.3 kPa (@20oC )(Water)
VAPOR DENS I T Y: T he highest known value is 0.62 (Air= 1) (Water).
VOL AT I L I T Y: Not available.
ODOR T HR ES HOL D: Not available.
W AT ER / OI L DI S T . COEFF.: T he product is much more soluble in water.
I ONI CI T Y (I N W AT ER ): Not available.
DI S PER S I ON PR OPER T I ES : See solubility in water, methanol.
S OL UB I L I T Y: Easily soluble in cold water, hot water, methanol. I nsoluble in diethl
ether, n-octanol.
S T AB I L I T Y AND R EACT I VI T Y DAT A
S T AB I L I T Y: T he product is stable.
I NS T AB I L I T Y T EMPER AT UR E: Not available.
CONDI T I ONS OF I NS T AB I L I T Y: Not available.
I NCOMPAT I B I L I T Y W I T H VAR I OUS S UB S T ANCES : Reactive with oxidizing agents.
Slightly reactive to reactive with acids.
COR R OS I VI T Y: Not considered to be corrosive for metals and glass.
S PECI AL R EMAR KS ON R EACT I VI T Y: Explodes in presence of bromine trifluoride
(Sodium chloride).
S PECI AL R EMAR KS ON COR R OS I VI T Y: Not available.
POL YMER I Z AT I ON: Will not occur.
T OXI COL OGI CAL I NFOR MAT I ON
R OUT ES OF ENT R Y: Eye contact. I nhalation. I ngestion.
T OXI CI T Y T O ANI MAL S :
Acute oral toxicity (LD50): 2500 mg/kg [G uinea pig]. (Potassium chloride).
DEVEL OPMENT AL T OXI CI T Y: C lassified Reproductive system/toxin/female,
Reproductive system/toxin/male [SUSPEC ED] [Phosphate Buffered Saline].
T
May cause damage to the following organs: blood, the reproductive system, upper
respiratory tract, central nervous system. May cause damage to the following organs:
Blood, the reproductive system, upper respiratory tract, central nervous system (C NS).
OT HER T OXI C EFFECT S ON HUMANS : Hazardous in case of inhalation. Slightly
hazardous in case of skin contact (irritant), of ingestion. Non-permeator by skin.
S PECI AL R EMAR KS ON CHR ONI C EFFECT S ON HUMANS : Not available.
S PECI AL R EMAR KS ON CHR ONI C EFFECT S ON HUMANS : Passes through the
placental barrier in animal (Potassium chloride).
S PECI AL R EMAR KS ON OT HER T OXI C EFFECT S ON HUMANS : Material is irritating
to mucous membranes and upper respiratory tract. (Sodium chloride).
Catalog # 11772-10 Page 5 of 7
Phosphate Buffered Saline
ECOL OGI CAL I NFOR MAT I ON
ECOT OXI CI T Y: Not available.
B OD5 AND COD: Not available.
PR ODUCT S OF B I ODEGR ADAT I ON: Possibly hazardous short term degradation
products are not likely. However, long term degradation products may arise.
T OXI CI T Y OF T HE PR ODUCT S OF B I ODEGR ADAT I ON: T he product itself and its
products of degradation are not toxic.
S PECI AL R EMAR KS ON T HE PR ODUCT S OF B I ODEGR ADAT I ON: Not available.
DI S POS AL CONS I DER AT I ONS
W AS T E DI S POS AL :
T R ANS POR T I NFOR MAT I ON
DOT CL AS S I FI CAT I ON: Not a DOT controlled material (United States).
I DENT I FI CAT I ON: Not applicable.
S PECI AL PR OVI S I ONS FOR T R ANS POR T : Not applicable.
OT HER R EGUL AT OR Y I NFOR MAT I ON
FEDER AL AND S T AT E R EGUL AT I ONS :
C alifornia prop. 65: T his product contains the following ingredients for
which the State of C alifornia has bound to cause cancer, birth defects or
other reproductive harm, which would require a warning under the
statute: Sodium C hloride
C alifornia prop. 65: T his product contains the following ingredients for
which the State of C alifornia has found to cause birth defects which would
require a warning under the statute: Sodium C hloride
T SC A8(b)inventory: Water, Sodium chloride, Potassium chloride; Sodium
phosphate, dibasic.
OT HER R EGUL AT I ONS :
OS HA: Hazardous by definition of Hazard Communication Standard (29 C 1910.1200)
FR
OT HER CL AS S I FI CAT I ONS :
W HMI S (CANADA): Class D-2A: Material causing other toxic effects (VERY T OXI C).
DS CL A (EEC): T his product is not classified according to the EU regulations.
HMI S (U.S .A.):
HEAL T H HAZ AR D: 1
FI R E HAZ AR D: 0
R EACT I VI T Y: 0
PER S ONAL PR OT ECT I ON: j
Catalog # 11772-10 Page 6 of 7
Phosphate Buffered Saline
NAT I ONAL FI R E PR OT ECT I ON AS S OCI AT I ON (U.S .A.)
HEAL T H: 1
FL AMMAB I L I T Y: 0
R EACT I VI T Y: 2
S PECI FI C HAZ AR D:
PR OT ECT I VE EQUI PMENT :
Not applicable.
Lab coat.
Vapor respirator. Be sure to use an approved/certified respirator or
equivalent. Wear appropriate respirator when ventilation is inadequate.
Splash goggles.
Catalog # 11772-10 Page 7 of 7
Phosphate Buffered Saline
|