EMS CATALOG NO: 19030
DATE: 04/15/97
Ninhydrin
EMS PRODUCT:
PAGE NUMBER: One of 4
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
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NUMBER
(215) 646-1566 CHEMTREC: (800) 424-9300
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FOR PRODUCT AND SALES INFORMATION
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CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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Ninhydrin
PRODUCT NAME:
CAS NO: 485-47-2
SYNONYMS: 2,2 Dihydroxy-1,3-Indandione
2,2-Dihydroxy-1H-Indene-1,3(2H)-Dione
1,2,3-Indantrione, 2-hydrate
1,2,3-Indantrione Monohydrate
Ninhydrin
Ninhydrin Hydrate
Triketohydridene Hydrate
APPEARANCE & ODOR: White to Yellow Powder.
250oC
MELTING POINT:
* * * EMS CATALOG NO: 19030 * * * (Page 2 of 4)
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HAZARDOUS IDENTIFICATION
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LABEL PRECAUTIONARY STATEMENTS:
Harmful. Harmful by inhalation, in contact with skin and if
swallowed. Irritating to eyes, respiratory system and
skin. Rubefacient. In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice.
After contact with skin, wash immediately with plenty of
water. Wear suitable protective clothing.
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FIRST AID MEASURES
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In case of contact, immediately flush eyes or skin with copious
amounts of water for at least 15 minutes while removing contaminated clothing and
shoes.
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is
difficult, give oxygen.
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Wash contaminated clothing before reuse.
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FIRE FIGHTING MEASURES
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EXTINGUISHING MEDIA:
Water spray. Carbon Dioxide, dry chemical powder or
appropriate foram.
SPECIAL FIREFIGHTING PROCEDURES:
Wear self-contained breathing apparatus and protective
clothing to prevent contact with skin and eyes.
UNUSUAL FIRE & EXPLOSIONS HAZARDS:
Emits toxic fumes under fire conditions.
* * * EMS CATALOG NO: 19030 * * * (Page 3 of 4)
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ACCIDENTAL RELEASE MEASURES
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Wear self-contained breathing apparatus, rubber boots and heavy
rubber gloves. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust.
Ventilate area and wash spill site after material pickup if complete.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Wear appropriate NIOSH/MSHA approved respirator, chemical resistant gloves, safety
goggles, other protective clothing.
Use only in a chemical fume hood. Safety shower and eye bath.
Avoid inhalation. Avoid all contact. Avoid prolonged or repeated exposure. Wash thor-
oughly after handling. Irritant.
Rubefacient. Harmful solid. Keep tightly closed. Light sensitive. Store in a cool dry
place.
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STABILITY AND REACTIVITY
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INCOMPATIBILITIES:
Strong oxidizing agents. May discolor on exposure to light.
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS:
Toxic Fumes of: Carbon Monoxide, Carbon Dioxide.
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TOXICOLOGICAL INFORMATION
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ACUTE EFFECTS:
May be harmful by inhalation, ingestion, or skin
absorption. Causes eye and skin irritation. Material is
irritating to mucous membranes and upper respiratory tract.
Causes reddening of the skin. To the best of our knowledge,
the chemical, physical, and toxicological properties have
not been thoroughly investigated.
ADDITIONAL INFORMATION:
This material is a rubefacient, skin contact will result in
a redding of the site with possible inflammation.
* * * EMS CATALOG NO: 19030 * * * (Page 4 of 4)
RTECS NO: NK5425000
1,3-Indandione, 2,2-Dihydroxy
TOXICITY DATA:
IPR-MUS LD50: 78 mg/kg CRSBAW 151,719,57
TARGET ORGAN DATA:
Behavioral (Somnolence)
Vascular (Regional or general arteriolar or venous dilation)
Lungs, thorax, or respiration (Dyspane)
Only selected registry of toxic effects of chemical
substances (RTECS) data is presented here. See actual entry
in RTECS for complete information.
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DISPOSAL CONSIDERATIONS
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Dissolve or mix the material with combustible solvent and burn in
a chemical incinerator equipped with an afterburner and scrubber. Observe all Federal,
State and Local environmental regulations.
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REGULATORY INFORMATION
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REVIEWS, STANDARDS, AND REGULATIONS:
NOH 1974: HZD A1175; NIS 1; TNF 33; NOS 2; TNE 594
NOES 1983: HZD A1175; NIS 4; TNF 476; NOS 9: TNE 5564;
TFE 4002
EPA
TSCA Chemical Inventory, January 1993
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ECOLOGICAL INFORMATION
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Data not yet available.
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