EMS CATALOG NO: 19327
EMS PRODUCT: Phenol Red
DATE: 10/30/2007
PAGE NUMBER: One of 6
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for personal injury or property damage to vendees, users or third
parties caused by the material. Such vendees or users assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
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FOR PRODUCT AND SALES INFORMATION
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
1. Product Identification
Synonyms: Phenol red; phenolsulfonphthalein; 4,4; -(3H-2,1-benzoxathiol-3-ylidene) bis-phenol, S,S-
dioxide.
CAS No.: 143-74-8
Molecular Weight: 354.38
Chemical Formula: C19H14O5S
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------
Phenol Red, Free Acid 143-74-8 100% YES
3. Hazards Identification
Emergency Overview
--------------------------
CAUTION! MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.
Safety Data Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 -Moderate
Lab Protective Equip: GOGGLES; LAB COAT, PROPER GLOVES
Storage Color Code: GREEN (General Storage)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Information on the human health effects from exposure to this substance is limited.
Inhalation:
May cause irritation to respiratory tract resulting in coughing and sneezing.
Ingestion:
Ingestion effects have not been studied completely but may exhibit symptoms similar to phenolphthalein,
such as an itching skin rash. May be a strong laxative.
Skin Contact:
May cause irritation with redness and pain.
Eye Contact:
May cause irritation and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
4. First Aid Measures
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an
unconscious person. Call a physician.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and
shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if
irritation develops.
Eye Contact:
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and
lower eyelids occasionally. Call a physician if irritation persists.
5. Fire Fighting Measures
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition
source.
Explosion:
2
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a
potential dust explosion hazard.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing
apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8.
Spills: Pick up and place in a suitable container for reclamation or disposal, using a method that does not
generate dust.
7. Handling and Storage
Keep in a tightly closed container. Protect from physical damage. Store in a cool, dry, ventilated area
away from sources of heat, moisture and incompatibilities. Containers of this material may be hazardous
when empty since they retain product residues (dust, solids); observe all warnings and precautions listed
for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as
possible. Local exhaust ventilation is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general work area. Please refer to the
ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for
details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to dust or mist is apparent and engineering controls are not
feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g.
lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or
instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied
respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Bright red, crystalline powder.
Odor:
Odorless.
Solubility:
Slightly soluble in water.
3
Specific Gravity:
No information found.
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
No information found.
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, sulfur oxides.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers.
Conditions to Avoid:
Incompatibles.
11. Toxicological Information
No LD50/LC50 information found relating to normal routes of occupational exposure. Investigated as a
mutagen..
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Phenol Red, Free Acid (143-74-8) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this material is not expected to evaporate significantly. When released into
water, this material is not expected to evaporate significantly.
Environmental Toxicity:
No information found.
13. Disposal Considerations
4
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved
waste disposal facility. Processing, use or contamination of this product may change the waste
management options. State and local disposal regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Phenol Red, Free Acid (143-74-8) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Phenol Red, Free Acid (143-74-8) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Phenol Red, Free Acid (143-74-8) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Phenol Red, Free Acid (143-74-8) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations
(CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
5
CAUTION! MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.
Label Precautions:
Wash thoroughly after handling.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use with adequate ventilation.
Avoid breathing dust.
Label First Aid:
If inhaled, remove to fresh air. Get medical attention for any breathing difficulty. In case of contact,
immediately flush eyes or skin with plenty of water for at least 15 minutes. If irritation develops call a
physician.
Product Use:
Laboratory Reagent.
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