Material Safety Data Sheet

                                           acc. to OSHA and ANSI

    Printing date 11/29/2001                                                Reviewed on 11/29/2001





�        1 Identification of substance:



     �    Product details:





     �    Trade name: 1,2-Propanediol





     �    Stock number: 20350 & 20352





     �    Supplier:

          ELECTRON MICROSCOPY SCIENCES

          321 Morris Road * P.O. Box 251

          Fort Washington, PA 19034

          CHEMTREC: (800) 424-9300

          Web Site: www.emsdiasum.com



�        2 Composition/Data on components:



     �    Chemical characterization:

            Description: (CAS#)

            1,2-Propanediol (CAS# 57-55-6), 100%



     �    Identification number(s): EMS Catalog #20350 & 20352



     �    Common name: Propylene Glycol



     �    EINECS Number: 200-338-0



�        3 Hazards identification



     �    Hazard description: · Not applicable



     �    Information pertaining to particular dangers for man and environment

          Not applicable



�        4 First aid measures



     �    After inhalation

          Supply fresh air. If required, provide artificial respiration. Keep patient warm.

          Seek immediate medical advice.



     �    After skin contact

          Immediately wash with water and soap and rinse thoroughly.

          Seek immediate medical advice.

    �    After eye contact

         Rinse opened eye for several minutes under running water. Then consult a doctor.



    �    After swallowing Seek medical treatment.



�       5 Fire fighting measures



    �    Suitable extinguishing agents

         CO2, extinguishing powder or water spray. Fight larger fires with water spray.



    �    Special hazards caused by the material, its products of combustion or

           resulting gases:

         In case of fire, the following can be released:

         Carbon monoxide (CO)



    �    Protective equipment:

         Wear self-contained respirator.

         Wear fully protective impervious suit.



�       6 Accidental release measures



    �    Person-related safety precautions:

         Wear protective equipment. Keep unprotected persons away.

         Ensure adequate ventilation



    �    Measures for environmental protection:

         Do not allow material to be released to the environment without proper governmental

         permits.



    �    Measures for cleaning/collecting:

         Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders,

         sawdust).



    �    Additional information:

         See Section 7 for information on safe handling

         See Section 8 for information on personal protection equipment.

         See Section 13 for disposal information.



�       7 Handling and storage







    �    Handling



    �    Information for safe handling:

         Keep container tightly sealed.

         Store in cool, dry place in tightly closed containers.

         No special precautions are necessary if used correctly.



    �    Information about protection against explosions and fires:

         No special measures required.



    �    Storage

    �    Requirements to be met by storerooms and receptacles:

         No special requirements.



    �    Information about storage in one common storage facility:

         Store away from oxidizing agents.

         Store away from reducing agents.



    �    Further information about storage conditions:

         This product is hygroscopic.

         Keep container tightly sealed.

         Store in cool, dry conditions in well sealed containers.



�       8 Exposure controls and personal protection



    �    Additional information about design of technical systems:

         Properly operating chemical fume hood designed for hazardous chemicals and having an

         average face velocity of at least 100 feet per minute.



         Components with limit values that require monitoring at the workplace:

         Not required.



    �    Additional information: No data





    �    Personal protective equipment



    �    General protective and hygienic measures

         The usual precautionary measures for handling chemicals should be followed.

         Keep away from foodstuffs, beverages and feed.

         Remove all soiled and contaminated clothing immediately.

         Wash hands before breaks and at the end of work.



    �    Breathing equipment:

         Use suitable respirator when high concentrations are present.



    �    Protection of hands: Impervious gloves



    �    Eye protection: Safety glasses



    �    Body protection: Protective work clothing.



�       9 Physical and chemical properties:







    �    Form: Liquid



    �    Color: Colorless



    �    Odor: Not determined



    �        Value/Range    Unit   Method



    �    Change in condition

    �   Melting point/Melting range:                        -60 ° C



    �   Boiling point/Boiling range:                        187 ° C



    �   Sublimation temperature / start:        Not determined





    �   Flash point:                                        107 ° C





    �   Ignition temperature:                               371 ° C





    �   Decomposition temperature:              Not determined





    �   Danger of explosion:

        Product does not present an explosion hazard.



    �   Explosion limits:



    �   Lower:                                              2.6 Vol %



    �   Upper:                                             12.6 Vol %





    �   Vapor pressure:         at     20 ° C               0.1 hPa





    �   Density:                at     20 ° C             1.036 g/cm3





    �   Solubility in / Miscibility with



    �   Water:                                  Partly miscible



�   10 Stability and reactivity



    �   Thermal decomposition / conditions to be avoided:

        Decomposition will not occur if used and stored according to specifications.



    �   Materials to be avoided:

        Oxidizing agents

        Reducing agents

        Acid chlorides

        Acid anhydrides



    �   Dangerous reactions No dangerous reactions known



    �   Dangerous products of decomposition: Carbon monoxide and carbon dioxide



�   11 Toxicological information



    �   Acute toxicity:

        LD/Lc50 values that are relevant for classification:

        Oral: LD50: 22000 mg/kg (mus)

        LD50: 20000 mg/kg (rat)

        LD50: 20000 mg/kg (rat)



    �   Primary irritant effect:



    �   on the skin: Irritant to skin and mucous membranes.



    �   on the eye: Irritating effect.



    �   Sensitization: No sensitizing effects known.



    �   Other information (about experimental toxicology):

        Mutagenic effects have been observed on tests with laboratory animals.

        Reproductive effects have been observed on tests with laboratory animals.



    �   Sub-acute to chronic toxicity:

        Human systemic effects by ingestion include general anesthesia, convulsions, and changes

        in surface EEG.



    �   Additional toxicological information:

        To the best of our knowledge the acute and chronic toxicity of this substance is not

        fully known.



�   12 Ecological information:



    �   General notes:

        Do not allow material to be released to the environment without proper governmental

        permits.



�   13 Disposal considerations







    �   Product:



    �   Recommendation

        Consult state, local or national regulations for proper disposal.



    �   Uncleaned packagings:



    �   Recommendation:

        Disposal must be made according to official regulations.



�   14 Transport information



        Not a hazardous material for transportation.





    �   DOT regulations:



    �   Hazard class:                None





    �   Land transport ADR/RID     (cross-border)



    �   ADR/RID class:                      None

    �   Maritime transport IMDG:



    �   IMDG Class:                None





    �   Air transport ICAO-TI and IATA-DGR:



    �   ICAO/IATA Class:           None





    �   Transport/Additional information:

        Not dangerous according to the above specifications.



�   15 Regulations







    �   Product related hazard information:

        Observe the general safety regulations when handling chemicals





    �   National regulations

        All components of this product are listed in the U.S. Environmental Protection Agency

        Toxic Substances Control Act Chemical Substance Inventory.





    �   Information about limitation of use:

        For use only by technically qualified individuals.



�   16 Other information:



        Employers should use this information only as a supplement to other information gathered

        by them, and should make independent judgment of suitability of this information to

        ensure proper use and protect the health and safety of employees. This information is

        furnished without warranty, and any use of the product not in conformance with this

        Material Safety Data Sheet, or in combination with any other product or process, is the

        responsibility of the user.