EMS CATALOG NO: 19550
EMS PRODUCT: PICRIC ACID
DATE: July 30, 2001
PAGE NUMBER: 1 of 8
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
321 MORRIS ROAD
P.O. BOX 251
FORT WASHINGTON, PA 19034 24 HOUR EMERGENCY PHONE NUMBER
(215) 646-1566 CHEMTREC: (800) 424-9300
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FOR PRODUCT AND SALES INFORMATION
_________________________________________________________________
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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PRODUCT NAME: PICRIC ACID
CAS NUMBER: 88-89-1
% BY WEIGHT: 100
CHEMICAL FORMULA: C6H2(NO3)3OH
SYNONYM: 2,4,6-trinitrophenol
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TOXICOLOGICAL DATA ON INGREDIENTS
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Picric Acid
LD50: Not Available.
LC50: Not Available.
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HAZARDS IDENTIFICATION
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POTENTIAL ACUTE HEALTH EFFECTS:
Very dangerous in case of skin contact (irritant), of
ingestion. Slightly dangerous to dangerous in case of eye
contact (irritant), of inhalation. Very slightly to
slightly dangerous in case of skin contact (corrosive,
permeator). This product is a severe eye irritant.
Prolonged exposure may result in skin burns and
ulcerations. Over-exposure by inhalation may cause
respiratory irritation. This product may irritate eyes and
skin upon contact.
POTENTIAL CHRONIC HEALTH EFFECTS:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
The substance is toxic to blood, kidneys, liver, mucous
membranes.
TOXICITY OF THE PRODUCT TO THE REPRODUCTIVE SYSTEM: Not
available.
Repeated or prolonged exposure to the substance can produce
target organs damage.
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FIRST AID MEASURES
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EYE CONTACT:
Check for and remove any contact lenses. IMMEDIATELY flush
eyes with running water for at least 15 minutes, keeping
eyelids open. COLD water may be used. DO NOT use an eye
ointment. Seek medical attention.
SKIN CONTACT:
If the chemical got onto the clothed portion of the body,
remove the contaminated clothes as quickly as possible,
protecting your own hands and body. Place the victim under
a deluge shower. If the chemical touches the victim's
exposed skin, such as the hands: Gently and thoroughly wash
the contaminated skin with running water and non-abrasive
soap. Be particularly careful to clean folds, crevices,
creases and groin. COLD water may be used. Cover the
irritated skin with an emollient. If irritation persists,
seek medical attention. Wash contaminated clothing before
reusing.
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SERIOUS SKIN CONTACT:
Wash with a disinfectant soap and cover the contaminated
skin with an anti-bacterial cream. Seek medical attention.
INHALATION:
Allow the victim to rest in a well ventilated area. Seek
immediate medical attention.
SERIOUS INHALATION:
Evacuate the victim to a safe area as soon as possible.
Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen.
If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical attention.
INGESTION:
Remove dentures if any. Watch for an obstruction in the
victim's mouth. Remove if possible what is causing the
obstruction but do not force fingers or a hard object
between victim's teeth. Have conscious person drink several
glasses of water or milk. INDUCE VOMITING by sticking
finger in throat. Seek immediate medical attention.
SERIOUS INGESTION:
Remove dentures if any. Watch for an obstruction in the
victim's mouth. Remove if possible what is causing the
obstruction but do not force fingers or a hard object
between the victim's teeth. If a soft pad can be inserted
between the victim's teeth, it will protect the tongue from
being bitten. A badly bleeding tongue immensely complicates
the patient's problems. Have conscious person drink several
glasses of water or milk. INDUCE VOMITING by sticking
finger in throat. Lower the head so that the vomit will not
reenter the mouth and throat. if convulsions occur, do not
restrain the victim, but do remove objects with which he
(she) might injure himself (herself) or orient the victim to
prevent him (her) from striking fixed heavy objects. If the
convulsions cease, turn the victim on the side or face down
so that any fluid in the mouth will drain. Seek medical
attention.
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FIRE AND EXPLOSION DATA
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FLAMMABILITY OF THE PRODUCT: Flammable.
AUTO-IGNITION TEMPERATURE: 300oC (572oF)
FLASH POINTS: Closed Cup: 150oC (302oF)
FLAMMABLE LIMITS: Not available.
PRODUCTS OF COMBUSTION: These products are carbon oxides (CO,
CO2), nitrogen oxides (NO, NO2...)
FIRE HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: Highly flammable
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in presence of open flames and sparks, of shocks, of heat.
Slightly flammable to flammable in presence of reducing
materials, of combustible materials.
EXPLOSION HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES:
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF MECHANICAL
IMPACT: Not available.
Extremely explosive in presence of open flames and sparks,
of heat.
FIRE FIGHTING MEDIA AND INSTRUCTIONS:
Flammable solid. Oxidizing material.
SMALL FIRE: Use DRY chemicals, CO2, water spray or foam.
LARGE FIRE: Use water spray or fog. DO NOT use water jet.
Cool containing vessels with water jet in order
to prevent pressure build-up, autoignition or
explosion. Use flooding quantities of water.
Avoid contact with organic materials
SPECIAL REMARKS ON FIRE HAZARDS: No additional remark.
SPECIAL REMARKS ON EXPLOSION HAZARDS: No additional remark.
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ACCIDENTAL RELEASE MEASURES
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SMALL SPILL:
Use appropriate tools to put the spilled solid in a
convenient waste disposal container.
LARGE SPILL:
Flammable solid. Oxidizing material. Stop leak if without
risk. Avoid contact with a combustible material (wood,
paper, oil, clothing...). Keep substance damp using water
spray. DO NOT touch spilled material. Use water spray
curtain to divert vapor drift. Prevent entry into sewers,
basements or confined areas; dike if needed. Eliminate all
sources of ignition. Call for assistance on disposal.
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HANDLING AND STORAGE
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PRECAUTIONS:
Keep locked up. Keep away from heat. Keep away from
sources of ignition. Keep away from combustible materials.
Keep away from direct sunlight or strong incandescent
light. Ground all equipment containing material. DO NOT
breathe dust. Avoid shock and friction. In case of
insufficient ventilation, wear suitable respiratory
equipment. If you feel unwell, seek medical attention and
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show the label when possible. Avoid contact with skin and
eyes. Keep away from incompatibles as metals, alkalis.
STORAGE:
Flammable materials should be stored in a separate storage
cabinet or room. Keep away from heat. Keep away from
sources of ignition. Keep container tightly closed. Keep
in a cool, well-ventilated place. Ground all equipment
containing material. Keep container dry. Keep in a cool
place.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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ENGINEERING CONTROLS:
Use process enclosures, local exhaust ventilation, or other
engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate
dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
PERSONAL PROTECTION:
Splash goggles. Lab coat. Dust respirator. Be sure to use
a MSHA/NIOSH approved respirator or equivalent. Gloves
(impervious). Wear appropriate respirator when ventilation
is inadequate.
PERSONAL PROTECTION IN CASE OF A LARGE SPILL:
Splash goggles. Full suit. Dust respirator. Boots.
Gloves. A self contained breathing apparatus should be used
to avoid inhalation of the product. Suggested protective
clothing might not be sufficient; consult a specialist
BEFORE handling this product.
EXPOSURE LIMITS:
TWA: 0.1 (mg/m3) from ACGIH
Consult local authorities for acceptable exposure limits.
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PHYSICAL AND CHEMICAL PROPERTIES
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PHYSICAL STATE AND APPEARANCE: Solid.
ODOR: Not available.
TASTE: Not available.
COLOR: Not available.
MOLECULAR WEIGHT: 229.11
pH(1% SOLN/WATER): Not available.
BOILING POINT: Decomposes (300oC or 572oF)
MELTING POINT: 122.5oC (252.5oF)
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CRITICAL TEMPERATURE: Not available.
SPECIFIC GRAVITY: 1.763 (Water=1)
VAPOR PRESSURE: Not available.
VAPOR DENSITY: 7.9 (Air=1)
VOLATILITY: Not available.
ODOR THRESHOLD: Not available.
WATER/OIL DIST. COEFF.: 0.0093325
IONICITY (IN WATER): Not available.
DISPERSION PROPERTIES: See solubility in water.
SOLUBILITY: Partially soluble in cold water.
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STABILITY AND REACTIVITY DATA
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STABILITY: Unstable.
INSTABILITY TEMPERATURE: Not available.
CONDITIONS OF INSTABILITY: No additional remark.
INCOMPATIBILITY WITH VARIOUS SUBSTANCES:
Extremely reactive or incompatible with metals.
Slightly reactive to reactive with alkalis
The product may undergo dangerous decomposition,
condensation or polymerization, it may react violently
with water to emit toxic gases or it may become
self-reactive under conditions of shock or increase in
temperature or pressure.
CORROSIVITY: Non-corrosive in presence of glass.
SPECIAL REMARKS ON REACTIVITY: No additional remark.
SPECIAL REMARKS ON CORROSIVITY: No additional remark.
POLYMERIZATION: No.
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TOXICOLOGICAL INFORMATION
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ROUTES OF ENTRY: Ingestion. Inhalation.
TOXICITY TO ANIMALS: LD50: Not available.
LC50: Not available.
CHRONIC EFFECTS ON HUMANS: The substance is toxic to blood,
kidneys, liver, mucous membranes.
TOXICITY OF THE PRODUCT TO THE REPRODUCTIVE SYSTEM: Not
available.
OTHER TOXIC EFFECTS ON HUMANS:
Very dangerous in case of skin contact (irritant), of
ingestion.
Slightly dangerous to dangerous in case of eye contact
(irritant), of inhalation.
Very slightly to slightly dangerous in case of skin contact
(corrosive, permeator).
SPECIAL REMARKS ON TOXICITY TO ANIMALS: No additional remark.
SPECIAL REMARKS ON CHRONIC EFFECTS ON HUMANS: No additional
remark.
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SPECIAL REMARKS ON OTHER TOXIC EFFECTS ON HUMANS: No additional
remark.
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ECOLOGICAL INFORMATION
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ECOTOXICITY: Not available.
BOD5 AND COD: Not available.
PRODUCTS OF BIODEGRADATION: These products are carbon oxides (CO,
CO2), nitrogen oxides (NO, NO2).
TOXICITY OF THE PRODUCTS OF BIODEGRADATION: The products of
degradation are more toxic.
SPECIAL REMARKS ON THE PRODUCTS OF BIODEGRADATION: No additional
remark.
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DISPOSAL CONSIDERATIONS
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WASTE DISPOSAL: Recycle to process, if possible. Consult your
local or regional authorities.
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TRANSPORT INFORMATION
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DOT CLASSIFICATION: DOT CLASS 4.1: Flammable solid.
IDENTIFICATION: Picric acid, wet NA1344 I
SPECIAL PROVISIONS FOR TRANSPORT: No additional remark.
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OTHER REGULATORY INFORMATION
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FEDERAL AND STATE REGULATIONS:
The following product(s) is (are) listed on SARA 313: Picric
Acid
The following product(s) is (are) listed by the State of
Massachusetts: Picric Acid
The following product(s) is (are) listed by the State of
Pennsylvania: Picric Acid
The following product(s) is (are) listed on TSCA: Picric
Acid
OTHER REGULATIONS:
OSHA: Hazardous by definition of Hazard Communication
Standard (29 CFR 1910.1200).
CANADIAN ENVIRONMENTAL PROTECTION ACT (CEPA):
This product is on the Domestic Substances List (DSL), and
is acceptable for use under the provisions of CEPA.
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OTHER CLASSIFICATIONS:
WHMIS (Canada): WHMIS CLASS C: Oxidizing material.
WHMIS CLASS F: Dangerously reactive material.
DSCL (EEC): R3-Extreme risk of explosion by shock, friction,
fire or other sources of ignition.
R5-Heating may cause an explosion.
R11-Highly flammable.
HMIS (U.S.A.)
HEALTH HAZARD 2
FIRE HAZARD 1
REACTIVITY 4
PERSONAL PROTECTION e
NATIONAL FIRE PROTECTION ASSOCIATION (U.S.A.)
HEALTH 3
FLAMMABILITY 4
REACTIVITY 4
SPECIFIC HAZARD OXY
PROTECTIVE EQUIPMENT:
Gloves (impervious).
Lab coat.
Dust respirator. Be sure to use a MSHA/NIOSH approved
respirator or equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.
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