SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 17/MAY/2005
Date Updated: 14/OCT/2004
Version 1.0
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name URANYL ACETATE DIHYDRATE
Product Number 73943
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
URANYL ACETATE DIHYDRATE 6159-44-0 208-767-5 092-002-00-3
Formula C4H6O6U.2H2O
Molecular Weight 424.15 AMU
Synonyms Bis(aceto)dioxouranium dihydrate *
Bis(aceto-O)dioxouranium dihydrate * Uranium,
bis(aceto-O)dioxo-, dihydrate (9CI) * Uranyl
acetate dihydrate
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Very toxic by inhalation and if swallowed. Danger of cumulative
effects. Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Handle as a radioactive spill.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
WORK PRACTICES
Use with adequate ventilation.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.2 mg/m3
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.2MG(U(/M3
OEL STEL 0.6 mg(U)/m3
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
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Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: Yellow
Form: Fine crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range 110 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 2.89 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. 275 掳C
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:10% in H2O, 20掳C
Soluble. Incomplete
Other Solvents: DUE TO PRESENCE OF BASIC
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Uranium oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: YR3600000
ACUTE TOXICITY
LD50
Oral
Rat
204 mg/kg
Remarks: Behavioral:Tremor. Skin and Appendages: Other: Hair.
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Nutritional and Gross Metabolic:Changes in:Body temperature
decrease.
LD50
Subcutaneous
Rat
8300 UG/KG
Remarks: Behavioral:Tremor. Skin and Appendages: Other: Hair.
Nutritional and Gross Metabolic:Changes in:Body temperature
decrease.
LD50
Oral
Mouse
242 mg/kg
Remarks: Behavioral:Tremor. Skin and Appendages: Other: Hair.
Nutritional and Gross Metabolic:Changes in:Body temperature
decrease.
LD50
Subcutaneous
Mouse
20400 UG/KG
Remarks: Behavioral:Tremor. Skin and Appendages: Other: Hair.
Nutritional and Gross Metabolic:Changes in:Body temperature
decrease.
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure may cause: Conjunctivitis. Blood effects. Symptoms may
be delayed. To the best of our knowledge, the chemical,
physical, and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be fatal if inhaled. Material may be irritating
to mucous membranes and upper respiratory tract.
Ingestion: May be fatal if swallowed.
TARGET ORGAN INFORMATION
Kidneys. Liver. Lungs.
CHRONIC EXPOSURE - CARCINOGEN
Result: Contains a radioactive isotope which may produce cancer
and genetic mutation.
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 50 MG/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Musculoskeletal system.
Species: Rat
Dose: 100 MG/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
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Result: Specific Developmental Abnormalities: Craniofacial
(including nose and tongue).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Mouse
Dose: 2 GM/KG
Route of Application: Oral
Exposure Time: (60D MALE/2W PRE/1-13D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death.
Species: Mouse
Dose: 990 MG/KG
Route of Application: Oral
Exposure Time: (60D MALE/14D PRE-4D POST)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Other postnatal measures or
effects.
Species: Mouse
Dose: 640 MG/KG
Route of Application: Oral
Exposure Time: (64D MALE)
Result: Effects on Fertility: Male fertility index (e.g., #
males impregnating females per # males exposed to fertile
nonpregnant females).
Species: Mouse
Dose: 1280 MG/KG
Route of Application: Oral
Exposure Time: (64D MALE)
Result: Paternal Effects: Testes, epididymis, sperm duct.
Species: Mouse
Dose: 1500 MG/KG
Route of Application: Oral
Exposure Time: (13-21D PREG/21D POST)
Result: Maternal Effects: Other effects. Effects on Newborn:
Weaning or lactation index (e.g., # alive at weaning per # alive
at day 4). Effects on Newborn: Other postnatal measures or
effects.
Species: Mouse
Dose: 4 MG/KG
Route of Application: Subcutaneous
Exposure Time: (10D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death. Specific Developmental
Abnormalities: Musculoskeletal system.
Species: Mouse
Dose: 5 MG/KG
Route of Application: Subcutaneous
Exposure Time: (6-15D PREG)
Result: Maternal Effects: Other effects. Effects on Fertility:
Pre-implantation mortality (e.g., reduction in number of
implants per female; total number of implants per corpora
lutea). Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
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12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Dispose of spilled material as radioactive waste. Consult local,
state, and federal regulations on the disposal of radioactive
waste.
14 - Transport Information
RID/ADR
UN#: 2910
Class: 7
Proper Shipping Name: Radioactive material, excepted
package, limited quantity of material
IMDG
UN#: 2910
Class: 7
Proper Shipping Name: RADIOACTIVE MATERIAL, EXCEPTED
PACKAGE - LIMITED QUANTITY OF MATERIAL
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2910
Class: 7
Proper Shipping Name: Radioactive material, excepted
package, limited quantity of material
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 092-002-00-3
INDICATION OF DANGER: R T+ N
Radioactive. Very toxic. Dangerous for the environment.
R-PHRASES: 26/28 33 51/53
Very toxic by inhalation and if swallowed. Danger of cumulative
effects. Toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
S-PHRASES: 20/21 45 61
When using do not eat, drink, or smoke. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible). Avoid release to the environment. Refer
to special instructions/safety data sheets.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
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or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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