PRODUCT #: D4386         NAME: 3,5-DINITROBENZOYL CHLORIDE

                     MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98

                        Printed Wednesday, March 12, 1903 9:04AM



Sigma Chemical Co.         Aldrich Chemical Co., Inc.     Fluka Chemical Corp.

P.O. Box 14508             1001 West St. Paul             1001 West St. Paul

St. Louis, MO 63178        Milwaukee, WI 53233            Milwaukee, WI 53233

Phone: 314-771-5765        Phone: 414-273-3850            Phone: 414-273-3850









SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -

    CATALOG #:            D4386

    NAME:                 3,5-DINITROBENZOYL CHLORIDE

SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -

    CAS #:     99-33-2

    MF: C7H3CLN2O5

    EC NO: 202-750-6

  SYNONYMS

    3,5-DINITROBENZOIC ACID CHLORIDE * 3,5-DINITROBENZOYL CHLORIDE *

SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -

  LABEL PRECAUTIONARY STATEMENTS

    CORROSIVE

    CAUSES BURNS.

    HEATING MAY CAUSE AN EXPLOSION.

    POSSIBLE RISK OF IRREVERSIBLE EFFECTS.

    POSSIBLE MUTAGEN.

    LACHRYMATOR.

    IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF

    WATER AND SEEK MEDICAL ADVICE.

    TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING.

    WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE

    PROTECTION.

SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -

    IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS

    AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED

    CLOTHING AND SHOES.

    ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS

    WITH FINGERS.

    IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL

    RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.

    IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.

    CALL A PHYSICIAN.

    WASH CONTAMINATED CLOTHING BEFORE REUSE.

SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -

  EXTINGUISHING MEDIA

    CARBON DIOXIDE.

    DRY CHEMICAL POWDER.

  SPECIAL FIREFIGHTING PROCEDURES

    WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO

    PREVENT CONTACT WITH SKIN AND EYES.

    USE WATER SPRAY TO COOL FIRE-EXPOSED CONTAINERS.

  UNUSUAL FIRE AND EXPLOSIONS HAZARDS

    WATER HYDROLYZES MATERIAL LIBERATING ACIDIC GAS WHICH IN CONTACT

    WITH METAL SURFACES CAN GENERATE FLAMMABLE AND/OR EXPLOSIVE

    HYDROGEN GAS.

    MAY EXPLODE WHEN HEATED.

    EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -

    WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY



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               PRODUCT #: D4386         NAME: 3,5-DINITROBENZOYL CHLORIDE

                     MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98

                        Printed Wednesday, March 12, 1903 9:04AM



    RUBBER GLOVES.

    COVER WITH DRY-LIME, SAND, OR SODA ASH. PLACE IN COVERED CONTAINERS

    USING NON-SPARKING TOOLS AND TRANSPORT OUTDOORS.

    VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -

    REFER TO SECTION 8.

  ADDITIONAL INFORMATION

    THIS MATERIAL IS INCOMPATIBLE WITH INORGANIC NITRATES AND CHLORIDES.

    DANGER: MAY PRESENT SEVERE EXPLOSION HAZARD. IT HAS BEEN SUGGESTED

    THAT FIRE BE FOUGHT BY UNMANNED EQUIPMENT USING WATER. AVOID PHYSICAL

    DAMAGE TO CONTAINERS.

SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -

    WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT

    GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.

    USE ONLY IN A CHEMICAL FUME HOOD.

    SAFETY SHOWER AND EYE BATH.

    FACESHIELD (8-INCH MINIMUM).

    DO NOT BREATHE DUST.

    DO NOT GET IN EYES, ON SKIN, ON CLOTHING.

    AVOID PROLONGED OR REPEATED EXPOSURE.

    WASH THOROUGHLY AFTER HANDLING.

    CORROSIVE.

    LACHRYMATOR.

    POSSIBLE MUTAGEN.

    KEEP TIGHTLY CLOSED.

    MOISTURE SENSITIVE

    STORE UNDER NITROGEN.

    STORE IN A COOL DRY PLACE.

SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -

  APPEARANCE AND ODOR

    YELLOW-TAN POWDER

  PHYSICAL PROPERTIES

    BOILING POINT:          196 C/11MM.

    MELTING POINT:       69 C TO 71 C

    VAPOR DENSITY:      7.6

SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -

  INCOMPATIBILITIES

    WATER

    ALCOHOLS

    OXIDIZING AGENTS

    STRONG BASES

  HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS

    THERMAL DECOMPOSITION MAY PRODUCE CARBON MONOXIDE, CARBON DIOXIDE,

    AND NITROGEN OXIDES.

    HYDROGEN CHLORIDE GAS

    PHOSGENE GAS

SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -

  ACUTE EFFECTS

    HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.

    CAUSES BURNS.

    MATERIAL IS EXTREMELY DESTRUCTIVE TO TISSUE OF THE MUCOUS MEMBRANES

    AND UPPER RESPIRATORY TRACT, EYES AND SKIN.

    INHALATION MAY RESULT IN SPASM, INFLAMMATION AND EDEMA OF THE

    LARYNX AND BRONCHI, CHEMICAL PNEUMONITIS AND PULMONARY EDEMA.

    SYMPTOMS OF EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING,

    WHEEZING, LARYNGITIS, SHORTNESS OF BREATH, HEADACHE, NAUSEA AND

    VOMITING.



                                          Page 2

               PRODUCT #: D4386         NAME: 3,5-DINITROBENZOYL CHLORIDE

                     MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98

                        Printed Wednesday, March 12, 1903 9:04AM



  CHRONIC EFFECTS

    LABORATORY EXPERIMENTS HAVE SHOWN MUTAGENIC EFFECTS.

    TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND

    TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.

  RTECS #: DM6637000

    BENZOYL CHLORIDE, 3,5-DINITRO-

    ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES

    (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR

    COMPLETE INFORMATION.

SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -

    DATA NOT YET AVAILABLE.

SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -

    CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF

    THIS MATERIAL.

    OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -

    CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.

SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -

  EUROPEAN INFORMATION

    CORROSIVE

    R 34

    CAUSES BURNS.

    R5

    HEATING MAY CAUSE AN EXPLOSION.

    R 40

    POSSIBLE RISK OF IRREVERSIBLE EFFECTS.

    S 26

    IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF

    WATER AND SEEK MEDICAL ADVICE.

    S 27

    TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING.

    S 36/37/39

    WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE

    PROTECTION.

  REVIEWS, STANDARDS, AND REGULATIONS

    OEL=MAK

    EPA GENETOX PROGRAM 1988, POSITIVE: HISTIDINE REVERSION-AMES TEST

    EPA TSCA SECTION 8(B) CHEMICAL INVENTORY

SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -

    THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO

    BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,

    FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING

    OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR

    PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.

    COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,

    FLUKA CHEMIE AG

    LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY









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