PRODUCT #: A10701 NAME: ACETOPHENONE, 99%
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 4:06PM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: A10701
NAME: ACETOPHENONE, 99%
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 98-86-2
MF: C8H8O
EC NO: 202-708-7
SYNONYMS
ACETOFENON (CZECH) * ACETOPHENON * ACETOPHENONE (ACGIH) *
ACETYLBENZENE * BENZENE, ACETYL- * BENZOYL METHIDE * ETHANONE, 1-
PHENYL- (9CI) * HYPNON * HYPNONE * KETONE, METHYL PHENYL * METHYL
PHENYL KETONE * 1-PHENYLETHANONE * PHENYL METHYL KETONE * RCRA WASTE
NUMBER U004 * USAF EK-496 *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HARMFUL
HARMFUL IF SWALLOWED.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
RISK OF SERIOUS DAMAGE TO EYES.
COMBUSTIBLE.
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS
WITH FINGERS.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
COMBUSTIBLE LIQUID.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
ABSORB ON SAND OR VERMICULITE AND PLACE IN CLOSED CONTAINERS FOR
DISPOSAL.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
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PRODUCT #: A10701 NAME: ACETOPHENONE, 99%
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 4:06PM
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
CHEMICAL SAFETY GOGGLES.
RUBBER GLOVES.
NIOSH/MSHA-APPROVED RESPIRATOR.
SAFETY SHOWER AND EYE BATH.
MECHANICAL EXHAUST REQUIRED.
AVOID INHALATION.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
SEVERE EYE IRRITANT.
KEEP TIGHTLY CLOSED.
KEEP AWAY FROM HEAT AND OPEN FLAME.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
YELLOW-TINTED LIQUID
PHYSICAL PROPERTIES
BOILING POINT: 202 C
MELTING POINT: 19 C TO 20 C
FLASHPOINT 180 F
82C
AUTOIGNITION TEMPERATURE: 1058 F 569C
VAPOR PRESSURE: 0.45MM 25 C
SPECIFIC GRAVITY: 1.030
VAPOR DENSITY: 4.1
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
STRONG BASES
STRONG REDUCING AGENTS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
HARMFUL IF SWALLOWED.
MAY BE HARMFUL IF INHALED.
MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN.
CAUSES SKIN IRRITATION.
CAUSES SEVERE EYE IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
RTECS #: AM5250000
ACETOPHENONE
IRRITATION DATA
SKN-RBT 10 MG/24H OPEN JIHTAB 26,269,1944
SKN-RBT 515 MG OPEN MLD UCDS** 12/27/1971
EYE-RBT 750 UG SEV AJOPAA 29,1363,1946
TOXICITY DATA
ORL-RAT LD50:815 MG/KG GTPZAB 26(8),53,1982
ORL-MUS LD50:740 MG/KG GTPZAB 26(8),53,1982
IPR-MUS LD50:200 MG/KG NTIS** AD277-689
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PRODUCT #: A10701 NAME: ACETOPHENONE, 99%
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 4:06PM
SKN-RBT LD50:15900 UL/KG UCDS** 12/27/1971
SKN-GPG LD50:>20 ML/KG JIHTAB 26,269,1944
ORL-MAM LD50:2700 MG/KG GTPZAB 32(10),25,1988
IHL-MAM LC50:1200 MG/M3 GTPZAB 32(10),25,1988
TARGET ORGAN DATA
BEHAVIORAL (SOMNOLENCE)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
THIS COMBUSTIBLE MATERIAL MAY BE BURNED IN A CHEMICAL INCINERATOR
EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT ALDRICH CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
EC INDEX NO: 606-042-00-1
HARMFUL
R 22
HARMFUL IF SWALLOWED.
R 36
IRRITATING TO EYES.
S 26
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-TWA 49 MG/M3 (10 PPM) DTLVS* TLV/BEI,1996
OEL-HUNGARY:TWA 15 MG/M3;STEL 30 MG/M3;SKIN JAN 1993
OEL-RUSSIA:STEL 5 MG/M3;SKIN JAN 1993
NOES 1983: HZD 80265; NIS 48; TNF 4433; NOS 61; TNE 78624; TFE 31148
EPA GENETOX PROGRAM 1988, NEGATIVE: E COLI POLA WITHOUT S9; E COLI POLA
WITH S9
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
ON EPA IRIS DATABASE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
U.S. INFORMATION
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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