PRODUCT #: 00400 NAME: ACETANILIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:16AM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: 00400
NAME: ACETANILIDE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 103-84-4
MF: C8H9NO
EC NO: 203-150-7
SYNONYMS
ACETAMIDE, N-PHENYL- * ACETAMIDOBENZENE * ACETANIL * ACETANILID *
ACETIC ACID ANILIDE * ACETOANILIDE * ACETYLAMINOBENZENE *
ACETYLANILINE * N-ACETYLANILINE * AN * ANILINE, N-ACETYL- *
ANTIFEBRIN * PHENALGENE * PHENALGIN * N-PHENYLACETAMIDE * USAF EK-3 *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
TOXIC (USA)
HARMFUL (EU)
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER.
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES.
IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS
AMOUNTS OF WATER.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
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PRODUCT #: 00400 NAME: ACETANILIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:16AM
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
CHEMICAL SAFETY GOGGLES.
RUBBER GLOVES.
NIOSH/MSHA-APPROVED RESPIRATOR.
SAFETY SHOWER AND EYE BATH.
USE ONLY IN A CHEMICAL FUME HOOD.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
WASH THOROUGHLY AFTER HANDLING.
TOXIC.
IRRITANT.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
OFF-WHITE TO GREY CHIPS
PHYSICAL PROPERTIES
MELTING POINT: 113 TO 116C
FLASHPOINT 321.80F
161C
AUTOIGNITION TEMPERATURE: 1004 F 539C
VAPOR PRESSURE: 1MM 114 C
VAPOR DENSITY: 4.65
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
STRONG BASES
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
NITROGEN OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
MAY CAUSE CYANOSIS (BLUE-GRAY COLORING OF SKIN AND LIPS CAUSED BY
LACK OF OXYGEN).
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
RTECS #: AD7350000
ACETANILIDE
TOXICITY DATA
ORL-MAN LDLO:56 MG/KG/H-I AJMSA9 122,770,1901
UNR-MAN LDLO:59 MG/KG 85DCAI 2,73,1970
ORL-RAT LD50:800 MG/KG JPETAB 54,159,1935
IPR-RAT LD50:540 MG/KG JAPMA8 48,204,1959
ORL-MUS LD50:1210 MG/KG TXAPA9 19,20,1971
IPR-MUS LD50:500 MG/KG NTIS** AD277-689
TARGET ORGAN DATA
PERIPHERAL NERVE AND SENSATION (SPASTIC PARALYSIS WITH/WITHOUT SENSORY CH
BEHAVIORAL (SLEEP)
BEHAVIORAL (HALLUCINATIONS, DISTORTED PERCEPTIONS)
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PRODUCT #: 00400 NAME: ACETANILIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:16AM
LUNGS, THORAX OR RESPIRATION (CYANOSIS)
LUNGS, THORAX OR RESPIRATION (RESPIRATORY STIMULATION)
GASTROINTESTINAL (DECREASED MOTILITY OR CONSTIPATION)
KIDNEY, URETER, BLADDER (CHANGES IN TUBULES)
BLOOD (METHEMOGLOBINEMIA-CARBOXHEMOGLOBINEMIA)
NUTRITIONAL AND GROSS METABOLIC (BODY TEMPERATURE DECREASE)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT FLUKA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
HARMFUL
R 20/21/22
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
R 36/37/38
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
S 26
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
S 28
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER.
S 36/37/39
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
NOHS 1974: HZD A1053; NIS 2; TNF 28; NOS 2; TNE 66
NOES 1983: HZD A1053; NIS 3; TNF 716; NOS 19; TNE 10584; TFE 6423
EPA GENETOX PROGRAM 1988, NEGATIVE: HOST-MEDIATED ASSAY
EPA GENETOX PROGRAM 1988, INCONCLUSIVE: HISTIDINE REVERSION-AMES TEST
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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