MATERIAL SAFETY DATA SHEET
2522 Plantation Center Drive www.ciscochem.com
Matthews, NC 28105
(704) 845 9440
PRODUCT NAME: Dipropylene Glycol Methyl Ether
CHEMICAL NAME: Dipropylene Glycol Methyl Ether
SYNOMYMS: Dipropylene Glycol Monomethyl Ether
CAS NUMBER: 34590-94-8
PROPERTIES: Appearance/General info: colorless with a mild ether odor in moderate concentrations but a strong objec-
tionable odor at 1000 ppm.
Physical State: Liquid
Odor threshold: 210 mg/m3 odor low; 6000 mg/m3 odor high
Vapor pressure (kPa): 0.3 mm Hg at 68 F (20 c); o.4 mm Hg at 79 F (26 c)
Formula Weight: 148.2
Specific Gravity (H2O=1, at 4 c): 0.951
Refractive index: 1.419 at 77 F (25 c)
Boiling Point: 374 F (190 c)
Freezing/Melting Point: -112 F (-180 c)
Viscosity: 3.5 cP at 77 F (25 c)
Surface tension: Miscible
Other Solubilities: Miscible with acetone, ethanol, benzene, carbon tetrachloride, ether, methanol, mono-
chlorobenzene, VM&P naptha, and petroleum ether.
Stability and Reactivity: Stability/Polymerization/conditions to Avoid: Dipropylene glycol methyl ether is
stable at room temperature in closed containers under normal storage and handling conditions. Hazardous
polymerization cannot occur. Avoid sources of ignition, heat, and oxidizers.
Storage incompatibilities: strong oxidizers.
HAZARDS: Hazardous Decomposition Products: thermal oxidative decomposition of dipropylene glycol methyl ether
can produce toxic gases as carbon monoxide and carbon dioxide.
Hazard Identification: Colorless liquid; mild, pleasant ether-like odor. Irritating to eyes/repiratory tract.
Other Acute Effects: CNS depression. Combustible.
Potential Health Effects
Target Organs: eyes, respiratory and central nervous systems; in animals (at high concentrations): liver,
kidneys, and heart.
Primary Entry Routes: Skin absorption, skin and/or eye contact, and inhalation.
Acute Effects
Inhalation: Due to its low vapor pressure, dipropylene glycol methyl ether vapors do not present a signifi-
cant inhalation hazard. However, exposure to vapor or mists of dipropylene glycol methyl ether causes
nose and throat irritation, headache, dizziness, lightheadedness, and may cause loss of consciousness.
High concentrations cause marked irritation of the nasal mucous membranes.
Eye: direct contact or exposure to high vapor or mist concentrations causes transient irritation.
Skin: Dipropylene glycol methyl ether is not found to be a skin irritant to humans, however it may be
absorbed through the skin.
Ingestion: None reported; low order of toxicity following acute ingestion.
Carcinogenicity: NTP- Not listed; IARC 鈥? Not listed; OSHA 鈥? Not listed; NIOSH- Not listed; ACGIH
鈥? Not listed; EPA 鈥? Not listed; MAK- Not listed.
Medical conditions aggravated by long-term Exposure:
Based on animal studies, liver and kidney disease and existing ailments of the CNS may be aggravated by
repeated exposure by very high concentrations.
Chronic effects:
Based on animal studies repeated exposure to very high concentrations may effect the liver and kidneys.
Note: In general, Propylene glycol ethers are not associated with potent hematopoietic, spermatotoxic, or
teratogenic effects because they are metabolized differently than the ethylene glycol ether.
FIRE FIGHTING Flash Point: 186 F (86 c), Closed Cup
MEASURES: Autoignition Temperature: None reported.
LEL: 1.1% v/v at 392 F (200 c)
UEL: 3.0% V/V AT 392 F (200 c)
Flammability Classification: OSHA Class IIIA combustible liquid
Extinguishing Media: Use dry chemical, carbon dioxide (CO 2), water spray, or foam extinguishers.
General Fire Hazards/Hazardous Combustion Products: Toxic gasses (such as carbon monoxide and car-
p.1
[MSDS: DIPROPYLENE GLYCOL MONOMETHYL ETHER]
MATERIAL SAFETY DATA SHEET
2522 Plantation Center Drive www.ciscochem.com
Matthews, NC 28105
(704) 845 9440
bon dioxide) may be produced in a fire.
Fire 鈥? Fighting Instructions: If feasible and with out undue risk, remove containers from fire hazard area.
Do not release from fire control methods to sewers or waterways. Because fire may produce toxic thermal
decomposition products, wear a self-contained breathing apparatus (SCBA) with a full face piece operated
in pressure-demand or positive-pressure mode.
PERSONAL Engineering Controls: Where feasible, enclose operations and use local exhaust ventilation at the site of
PROTECTION chemical release. If local exhaust ventilation or enclosure is not used, wear respirators if concentrations
MEASURES: exceed the permissible exposure limits. Where possible, automatically pump liquid dipropylene glycol
methyl ether from drums or other storage containers to process containers in a closed system. Provide gen-
eral or local exhaust ventilation systems to maintain airborne concentrations below OSHA PEL (SEC.2).
Local exhaust ventilation is preferred because it prevents contaminant dispersion into the work areas by
controlling it as it source.
Administrative Controls: Consider replacement and periodic medical exams with emphasis on hepatic,
CNS, and renal functions of workers. Post hazard and warning information in the work area and educate
workers about the hazards of working with dipropylene glycol methyl ether.
Personal Protective Clothing/equipment: Wear chemical protective gloves, boots, aprons, and gauntlets
to prevent prolonged or repeated skin contact. Wear splash-proof chemical goggles and face shield, per
OSHA eye- and face- protection regulations (29 CFR 1910.133). Contact lenses are not eye protective
devices. Appropriate eye protection must be worn. Contact lenses should not be worn when working this
chemical.
Respiratory Protection: Seek professional advice prior to respirator selection and use. Follow OSHA
respirator regulations (29 CFR 1910.134) and for concentrations <=600 ppm, wear MSHA/NOISH-ap-
proved supplied-air respirator or any SCBA with a full face piece. Select respirator based on its suitability
to provide adequate worker protection for given working conditions, level of airborne contamination, and
presence of sufficient oxygen. For emergency or non routine operations (cleaning spills, reactor vessels,
or storage tanks), wear an SCBA. Warning! Air-purifying respirators do not protect workers in oxygen-
deficient atmospheres. If respirators are used, OSHA requires a written respiratory protection program that
includes at least: medical certification, training, fit-testing, periodic environmental monitoring, mainte-
nance, inspection, cleaning, and convenient, sanitary storage areas.
Other: Promptly change contaminated clothing. Separate contaminated work clothes from street clothes.
Remove this material from shoes and clean personal protective equipment . Inform laundry personnel of
the possible hazards associated with laundering clothing contaminated with dipropylene glycol methyl
ether. Make emergency eyewash stations, safety/quick-drench showers, and washing facilities available in
work area.
OSHA PEL:
EMERGENCY & FIRST Inhalation: Remove exposed person to fresh air and support breathing as needed.
AID PROCEDURES: Eye contact: do not allow victim to rub or keep eyes tightly shut. Gently lift eyelids and flush immediate-
ly and continuously with flooding amounts of water for 15 minutes. Consult a Physician or ophthalmolo-
gist if pain and irritation develop.
Skin Contact: Quickly remove contaminated clothing. Rinse with flooding amounts of water. Wash ex-
posed area with soap and water. For redden or blistered skin, consult a physician.
Ingestion: Never give anything by mouth to a unconscious or convulsing person. Contact a poison center.
Unless the poison control center advises otherwise, have the conscious and alert person drink 1 to 2 glasses
of water. Consult a physician before inducing vomiting.
After First Aid, get appropriate in-plant, paramedic, or community medical support.
EXPOSURE OSHA PEL:
LIMITS: TWA 鈥? 100ppm; 600mg/m3; skin
OSHA PEL Vacated 1989 Limits:
TWA 鈥? 100 PPM; 600 mg/m3
STEL 鈥? 1500 ppm; 900 mg/m3
ACGIH TLV:
TWA 鈥? 100 ppm;
STEL 鈥? 150 ppm; skin.
NIOSH REL:
TWA 鈥? 100 ppm, 600 mg/m3;
STEL 鈥? 150 ppm, 900 mg/m3; skin.
p.2
[MSDS: DIPROPYLENE GLYCOL MONOMETHYL ETHER]
MATERIAL SAFETY DATA SHEET
2522 Plantation Center Drive www.ciscochem.com
Matthews, NC 28105
(704) 845 9440
IDLH Level:
600 ppm.
DFG (Germany) MAK
TWA 鈥? 50 ppm;
PEAK 鈥? 50 ppm;
Values for mixture of isomers.
TOXICOLOGICAL Acute oral Effects:
INFORMATION: Rat, oral, LD 50 : 5135 mg/kg produced toxic effects: behavioral 鈥? affecting sleep.
Dog, oral, LD 50 : 7500 mg/kg; toxic effects: lungs, thorax, or respiration 鈥? other changes.
Acute Skin Effects:
Rabbit, skin, LD 50 : 10 mL/kg.
Rat, skin LD 50 : 9500 mg/kg.
Rabbit, skin : 10 to 20 mL/kg produced some transient weight loss and some narcosis.
Irritation Effects:
Rabbit, eye : 50 mg/24 hr produced mild irritation.
Human, eye : 8 mg caused a mild reaction.
Rabbit, skin : 500 mg (open Draize test) produced mild irritation.
Other Effects:
Rat, oral : 4mL/kg resulted in renal tabular degeneration.
Dog, IV : 6 mL/kg caused CNS depression.
Dog, 5 mL/kg produced no evidence of toxicity.
ECOLOGICAL Environmental Fate:
INFORMATION: Because of dypropylene glycol methyl ether鈥檚 high solubility and low vapor pressure, it is expected to
partition to the aquantic phase of the environment. In water it is not expected to sorb to sediments or bio-
concentrate. Evaporative transfer from water to the atmosphere will be minimal. The estimated half-life in
the atmosphere is 3.4 hr. Biodegradation is the primary removal mechanism of dipropylene glycol methyl
ether. Photolysis and hydrolysis are probably insignificant. BOD values: 5 day 鈥? 0%; 10 day 鈥? 0%; 20
day- 31%. It is highly mobile and will leach to groundwater.
Ecotoxicity: Data not found
DISPOSAL Contact your supplier or a licensed contractor for detailed recommendations. Follow applicable Federal,
CONSIDERAIONS: state. And local regulations.
CARCINOGENIC NTP- Not listed; IARC 鈥? Not listed; OSHA 鈥? Not listed; NIOSH- Not listed; ACGIH 鈥? Not listed; EPA
PROPERTIES & 鈥? Not listed; MAK- Not listed.
NOTIFICATIONS:
TRANSPORT Shipping Name an Description : Combustible liquid, n.o.s
INFORMATION: ID : NA1993
Hazard Class : Combustible liq
Packing group : III 鈥? Minor Danger
Symbols : D G
Label Codes : None
Special Provisions : IB3, T1, T4, TP1
Packaging : Exceptions : 150 Non-bulk: 203 Bulk : 241
Quantity Limitations : Passenger aircraft/rail : 60 L Cargo aircraft only : 220 L
Vessel Stowage : Location : A Other:
HANDLING & Handling Precautions: Avoid skin and eye contact. Use with ventilation sufficient to reduce airborne
STORAGE: concentrations to nonhazardous levels (see Sec.2). Wear personal protective clothing and equipment (see
Sec.8) to prevent contact. Keep away from sources of ignition including tobacco products. Open flames
are prohibited where dipropylene glycol methyl ether is handled, use or stored.
Never eat, drink or smoke in work areas. Wash thoroughly immediately after exposure to dipropylene gly-
col methyl ether and at the end of each work shift. Practice good personal hygiene after using this mate-
rial, especially before eating, drinking, smoking, using the toilet, or applying cosmetics.
p.3
[MSDS: DIPROPYLENE GLYCOL MONOMETHYL ETHER]
MATERIAL SAFETY DATA SHEET
2522 Plantation Center Drive www.ciscochem.com
Matthews, NC 28105
(704) 845 9440
Recommended Storage Methods: Store in tightly closed containers in a cool, well-ventilated area away
from strong oxidizres, heat, and ignition sources. Inspect periodically.
Regulatory Requirements: follow applicable OSHA regulations.
p.4
[MSDS: DIPROPYLENE GLYCOL MONOMETHYL ETHER]
|