MATERIAL SAFETY DATA SHEET (MSDS)
PYRIDINEHYDRO BROMIDE
Product name Pyridine Hydrobromide - PyHBr
MSDS code PYRBR
1. Identification of the substance & the company
Chemical name Pyridine hydrobromide
Synonym(s) Pyridinium Bromide
Chemical formula C5H5N.HBr
CAS number 18820-82-1
Supplier: Chemcon Speciality Chemicals Pvt.Ltd.
Marketing Office: D-34, Sardar Estate, Ajwa Road, Baroda 鈥? 390019 INDIA
Telephone number: +91-265-2511271 +91-265-2512088 Fax: +91-265-2561032
Email: expo@cscpl.com Website : www.cscpl.com
2. Composition / information on ingredients
(Not Specifications)
Components Weight % EINECS No. Classification Annex No.
Pyridine Hydrobromide
18820-82-1
98% min 242-600-7 Xn: R22; Xi: R36
Pyridine
110-86-1
< 0.9% 203-809-9 F: R11; Xn:
R20/21/22
613-002-00-7
This material is intended primarily for use as an intermediate in the Pharmaceutical, Photographic and other
fine Chemical Industries. Its use however is not limited to those stated.
3. Hazards identification
Important hazards Harmful: Irritant to eyes and skin.
NFPA Ratings (Scale 0-4) Health = 1, Fire = 0, Reactivity = 1.
4. First-aid measures
Eye contact Holding the eyelids apart, flush eyes promptly with copious flowing water for at
least 20 minutes. Get medical attention immediately.
Skin contact Wash thoroughly with copious flowing water for at least 15 minutes. Wash clothing
before reuse. Get medical attention immediately.
Inhalation Remove to fresh air.
Keep him quiet and warm. Apply artificial respiration if necessary and get medical
attention immediately.
Ingestion DO NOT INDUCE VOMITING
If swallowed, wash mouth thoroughly with plenty of water and give water to drink.
Get medical attention immediately.
NOTE: Never give an unconscious person anything to drink.
After handling, wash before eating, drinking or smoking.
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5. Fire - fighting measures
Flash point None
Flammable/Explosion limits
- Lower (% vol) Not Determined
- Upper (% vol) Not Determined
Auto-ignition temperature Not self-ignitable
Suitable extinguishing media Carbon dioxide, dry chemicals, foam, water spray (fog).
Material is not combustible. Use extinguishing media appropriate to surrounding fire conditions.
Fire fighting procedure Wear self-contained breathing apparatus in positive
pressure mode and appropriate protective clothing.
Unusual fire and explosion hazards When heated to decomposition, may release poisonous
and corrosive fumes of Bromine, Carbon Dioxide, Carbon Monoxide, Nitrogen Oxides (NOx), Hydrogen
Bromide and Pyridine.
6. Accidental release measures
Personal precautions Wear respirator, chemical safety goggles, rubber gloves and boots.
Methods for cleaning up Sweep up, place in a suitable container and hold for waste disposal.
Avoid raising dust.Ventilate area and wash spill site after material pickup is complete.
7. Handling and storage
Handling Handle in accordance with good industrial hygiene and safety procedures.
Storage Store in a dry, cool, well-ventilated area
8. Exposure controls / personal protection
Exposure Limits :
Components Weight % ACGIH-TLV Data
Pyridine Hydrobromide 18820-82-1
98% min Not determined Pyridine 110-86-1
< 0.9% TLV (as TWA): 5 ppm; 16 mg/m3
Ventilation requirements Mechanical ventilation is recommended. Use local exhaust at source of vapour.
Personal protective equipment:
- Respiratory protection Wear a suitable respiratory mask.
- Hand protection PVC gloves
- Eye protection Chemical safety goggles or face shield with safety glasses.
- Skin and body protection appropriated protective clothing.
Hygiene measures Safety shower and eye-bath should be provided. Do not eat, drink or smoke until,
after-work showering and changing clothes.
9. Physical and chemical properties
Physical state Solid
Molecular weight 159.95
Melting point/range 219掳C
Boiling point/range N/A
Vapour pressure Not available
Solubility:
- Solubility in water Soluble
- Solubility in other solvents Insoluble in most common organic solvents
Appearance White to off-white powder
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10. Stability and reactivity
Stability Stable under normal conditions.
Materials to avoid Strong oxidizers and strong bases.
Conditions to avoid Hygroscopic
Hazardous decomposition products
Hydrogen bromide,carbon dioxide, carbon monoxide and nitrogen oxides.
Hazardous polymerization Will not occur
11. Toxicological information
Toxicity Irritant to eyes and mucous membranes
Acute toxicity:
- Rat oral LD50 1498 (935 - 2401) mg/kg
- Rat dermal LD50 > 2000 mg/kg
Effects of overexposure: May be harmful by ingestion, by inhalation or by contact with skin and eyes.
May be an irritant to eyes, skin and mucous membranes.
Chronic toxicity Prolonged exposure may cause liver and kidney damage.
Mutagenicity Not mutagenic by the Ames Test
Carcinogenicity Not classified as a carcinogen by USA OSHA.
Not classified by NTP.
Not classified by IARC.
12. Ecological information
Aquatic toxicity No information available
Partition coefficient
(n-octanol/water)
Log10 Kow = -2.96 (est.)
Mobility Water will be the main medium for transport since the material is soluble in water
and thus could be widely spread, before its` natural decomposition , by streams
and rivers or even absorbed deeply in to the ground.
The powdered material will be dispersed by strong winds.
Persistence and degradability This material is relatively stable under normal conditions
13. Disposal considerations
Waste from residues / unused
products
Observe all federal, state and local environmental regulations when disposing of this material.
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber.
14. Transportation information
UN No. Not regulated
IMO Not regulated
ICAO/IATA Not regulated
ADR/RID Not regulated
UK Not regulated
DOT Proper shipping name: Pyridine Hydrobromide
Not regulated
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15. Regulatory information
Components Weight % EINECS No. Annex No.
Pyridine Hydrobromide
18820-82-1
98% min 242-600-7 None
Pyridine
110-86-1
< 0.9% 203-809-9 613-002-00-7
- Indication of danger Irritant, symbol required (Xi)
- Risk Phrases R 22 :Harmful if swallowed .R 36 :Irritating to eyes.
- Safety Phrases S 22 :Do not breathe dust. S 26 :In case of contact with eyes, rinse immediately with
plenty of water and seek medical advice.
USA Reported in the EPA TSCA Inventory
Canada Listed in NDSL
Japanese inventory (ENCS) 5-710X
16. Other information
Sources of key data used Toxic Substances Control Act (TSCA) Inventory, Pub: EPA, U.S.Government
Printing Office, Washington, U.S.A. (Through STN Data Base).
The European Inventory of Existing Chemical Substances, Pub: EEC, Office des
Publications Officielles des Communautes Europeennes, Boite Postale 1003, L-
1351, Luxembourg. (Through STN Data Base)
Handbook of Existing & New Chemical Substances, Editor: Chemical Products
Safety Division, Basic Industries Bureau, Ministry of International Trade & Industries, Tokyo, Japan.
(Through STN Data Base)
Note: Sections modified in version [3.00] - 3, 8, 12
MSDS valid until 30/03/2004
Although the information and recommendations set forth herein (herinafter "information") are presented in
good faith and believed to be correct as of the date hereof, Chemcon makes no representations as to the
completeness or accuracy thereof.Information is supplied upon the condition that the persons receiving
same will make their own determination as to its safety and suitability for their purposes prior to use.In no
event will Chemcon be responsible for damages of any nature whatsoever resulting from the use of or
reliance upon information.
NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESSED OR IMPLIED, OF
MERCHANTABILITY,FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER
NATURE, ARE MADE HEREUNDER WITH RESPECT TO INFORMATION OR THE
PRODUCT TO WHICH THE INFORMATION REFERS.
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