MATERIAL SAFETY DATA SHEET
SECTION 1 - PRODUCT IDENTIFICATION AND USE
PRODUCT IDENTIFICATION NUMBER (PIN):
PRODUCT IDENTIFIER
Silver nitrate Reagent SL120X
PRODUCT USE
Topical anti-infective
MANUFACTURERS NAME: SUPPLIERS NAME:
Xenex Labs XENEX LABORATORIES INC.
STREET ADDRESS: STREET ADDRESS:
2402 CANOE AVENUE
CITY: PROVINCE: CITY: PROVINCE:
COQUITLAM B.C.
POSTAL CODE: EMERGENCY TELEPHONE NO: POSTAL CODE: EMERGENCY TELEPHONE NO:
SPE100 V3K 6C2 (CHEMTREC) 1-800-424-9300
SECTION 2 - HAZARDOUS INGREDIENTS
HAZARDOUS INGREDIENTS
% CAS NUMBER LD50 / LC50 OF INGREDIENT
/ CHEMICAL FORMULA
(SPECIFY SPECIES) (SPECIFY ROUTE AND DOSE)
Silver nitrate Reagent 100 7761-88-8 RAT ORAL 1173 mg/kg
AgNO3 MOUSE ORAL 50mg/kg
GUINEA PIG ORAL 473 mg/kg
SECTION 3 - PHYSICAL DATA
PHYSICAL STATE AND APPEARANCE ODOR TASTE ODOR THRESHOLD (ppm)
Solid (Crystalline) Colorless, White Not Available Bitter, Metallic Not Available
MELTING POINT (C) BOILING POINT (C) VOLATILITY VAPOR PRESSURE VAPOR DENSITY
212掳C (413.6掳F) Decomposes 440掳C Not Available Not Available 5.8 (Air=1)
pH SPECIFIC GRAVITY DISPERSION PROPERTIES / SOLUBILITY
6 to 7 4.35 122 g/100 ml water @ 0掳C; 952 g /100 ml water @ 190 掳C
1 g/30 ml alcohol; 1g/ 6.5 ml boiling alcohol. 1 g/ 253 ml acetone
SECTION 4 - FIRE AND EXPLOSION DATA
NO YES
FLAMMABILITY IF YES, UNDER WHAT CONDITIONS?
Non-Flammable Contact with combustible or organic materials may cause fire. Silver nitrate mixed with dry powdered
magnesium may ignite explosively on contact with a drop of water. An explosive fulminate may be formed if silver nitrate
is mixed with alcohols Highly explosive is formed by the addition of calcium carbide to silver nitrate solution.
MEANS OF EXTINCTION
Not Applicable
FLASHPOINT (C) AND METHOD FLAMMABLE LIMITS (% BY VOLUME) CRITICAL TEMPERATURE
Not Available UPPER: Not Available LOWER: Not Available Not Available
AUTOIGNITION TEMPERATURE (C) HAZARDOUS COMBUSTION PRODUCTS
Not Available Not Available
MATERIAL SAFETY DATA SHEET
SL120X
PRODUCT IDENTIFIER
Silver nitrate Reagent
SECTION 5 - REACTIVITY DATA
YES NO IF NO, UNDER WHICH CONDITIONS?
CHEMICAL STABILITY
The product is stable
NO YES
INCOMPATIBILITY WITH OTHER SUBSTANCES IF SO, WHICH ONES?
Reactive with reducing agents, combustible materials, organic materials, alkalis, light.
REACTIVITY, AND UNDER WHAT CONDITIONS
Sensitive to light. Incompatible with antimony salts, arsenates, bromides, carbonates, chlorides, iodides, thiocyanates,
ferrous salts, hypophosphites, morphine salts, oils, creosote, phosphates, tannic acid, tart rates, vegetable decoctions,
and extracts, sodium hydroxide, charcoal, thimerosal, benzalkonium chloride, halogenated acids and their salts.
alcohols. Silver nitrate reacts with acetylene in presence of ammonia to form silver acetylide, a sensitive powerful
detonator when dry. Reaction between silver nitrate and chlorosulfonic acid is violent. Silver nitrate is reduced by
hydrogen sulfide in the dark. Silver nitrate is easily reduces to metallic silver by ferrous salts, arsenates, hypophosphites,
tartrates, sugars, tannins, volatile oils.
HAZARDOUS DECOMPOSITION PRODUCTS
The products of degradation are less toxic than the product itself
SECTION 6 - TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY
INGESTION
INHALATION
SKIN CONTACT SKIN ABSORPTION EYE CONTACT
EFFECTS OF ACUTE EXPOSURE TO PRODUCT
Very hazardous in case of skin contact (irritant, permeator, corrosive), of ingestion. of eye contact (irritant), of inhalation.
The amount of tissue damage depends on length of contact. Eye contact can result in corneal damage or blindness. Skin
contact can produce inflammation and blistering. Inhalation of dust will produce irritation to gastro-intestinal or respiratory
tract, characterized by burning, sneezing and coughing. Severe over-exposure can produce lung damage, choking,
unconsciousness or death. Prolonged exposure may result in skin burns and ulcerations. Over-exposure by inhalation
may cause respiratory irritation.
Skin: Causes severe irritation and burns. It may cause dermatitis. It may be absorbed through the skin. Eyes: Causes
severe irritation, corneal opacification, bleeding conjunctiva, burns of conjunctiva, argyria, blindness Inhalation: Causes
irritation of the respiratory tract and mucous membranes with possible chemical burns. Symptoms may include burning
sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, vomiting. Ingestion: Severe
gastrointestinal tract irritation and burns, pain and burning in the mouth, violent abdominal pain, argyria -
grayish/blackening of skin and mucous membranes, throat and abdomen, salivation, vomiting of black material,
diarrhea, hypermotility, ulcerative gingivitis . May affect kidneys (lesions of kidneys, anuria, ), lungs (lesions of lungs).
Other symptoms of acute silver poisoning may include shock, dizziness, tetany, somnolence, vertigo, coma,
convulsions), cardiovascular (fall in blood pressure), respiration (decreased respiration, cyanosis),
EFFECTS OF CHRONIC EXPOSURE TO PRODUCT
The substance is toxic to lungs. The substance may be toxic to mucous membranes, skin, eyes. Repeated or prolonged
exposure to the substance can produce target organs damage. Repeated exposure of the eyes to a low level of dust can
produce eye irritation. Repeated skin exposure can produce local skin destruction, or dermatitis. Repeated inhalation of
dust can produce varying degree of respiratory irritation or lung damage.
Absorption of the nitrate and reduction to nitrite may cause rare methemoglobinemia which is characterized by chocolate
-brown colored blood, headache, weakness, dizziness, shortness of breath, cyanosis (bluish skin due to deficient
oxygenation of blood), rapid heart rate. Eyes and Skin: Repeated or prolonged application on the skin or eyes causes
argyria, a bluish-grayish discoloration of the skin and eyes. Ingestion: Prolonged or repeated ingestion causes argyria
characterized by a permanent blue-slate gray discoloration of the skin, eyes, mucous membranes, and internal organs.
Prolonged or repeated ingestion may also affect the liver (hepatitis), kidneys (nephritis), cardiovascular system,
behavior/central nervous system (symptoms similar to acute ingestion), and metabolism (weight loss) Inhalation: Causes
argyrosis of the respiratory tract, chronic bronchitis, no discoloration of skin, eyes or mouth , but nasal mucosa may show
impregnation of silver nitrate. It may also affect the cardiovascular system, and blood.
EXPOSURE LIMITS IRRITANCY OF PRODUCT SENSITIZATION OF PRODUCT CARCINOGENICITY
YES Dermatitis Possible
TWA:0.01 (mg/m鲁 Ag)
REPRODUCTIVE TOXICITY MUTAGENICITY SYNERGISTIC PRODUCTS
TERATOGENICITY
Not Available Possible Possible Not Available
MATERIAL SAFETY DATA SHEET
SL120X
PRODUCT IDENTIFIER
Silver nitrate Reagent
SECTION 7 - PREVENTATIVE MEASURE
PERSONAL PROTECTIVE EQUIPMENT
GLOVES (SPECIFY) RESPIRATOR (SPECIFY) EYE (SPECIFY)
Yes ( impervious ) Approved / Certified respirator Safety goggles, face shield
FOOTWEAR (SPECIFY) CLOTHING (SPECIFY) OTHER (SPECIFY)
No Synthetic apron Eyewash equipment nearby
ENGINEERING CONTROLS (SPECIFY eg. VENTILATION, ENCLOSED PROCESS)
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
LEAK AND SPILL PROCEDURE
Use appropriate tools to put the spilled solid in a convenient waste disposal container.
WASTE DISPOSAL
According to local, provincial, and federal regulations.
HANDLING PROCEDURES AND EQUIPMENT
Keep container dry. Keep away from heat. Keep away from sources of ignition. Keep away from combustible material..
Do not ingest. Do not breathe dust. Never add water to this product. In case of insufficient ventilation, wear suitable
respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact
with skin and eyes.
STORAGE REQUIREMENTS
Keep container tightly closed. Keep container in a cool, well-ventilated area. Separate from acids, alkalies, reducing
agents and combustibles. See NFPA 43A, Code for the Storage of Liquid and Solid Oxidizers. Sensitive to light. Store in
light-resistant containers.
SPECIAL SHIPPING INFORMATION
CLASS 5.1: Oxidizing material WHMIS (Canada) CLASS C: Oxidizing material. CLASS E: Corrosive solid.
SECTION 8 - FIRST AID MEASURES
SPECIFIC MEASURES
Wash with soap and water for at least 15 minutes. Cover the irritated skin with an emollient.
SKIN
Remove contaminated clothing and shoes. Get medical attention if irritation develops. Wash
clothing before reuse, thoroughly clean shoes before reuse.
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of
EYES
water for at least 15minutes. Get medical attention
If inhaled remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give
INHALATION
oxygen. Get medical attention.
INGESTION Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. If large quantities of this material are swallowed, call a physician
immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
IF IRRITATION PERSISTS AND IN ALL OTHER CASES, GET IMMEDIATE MEDICAL ATTENTION.
SECTION 9 - PREPARATION DATE OF M.S.D.S.
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packa
If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the us
responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical
data judged to be reliable, Xenex Laboratories Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
PREPARED BY (GROUP, DEPARTMENT, ETC.) PHONE NUMBER DATE:
CONTROL DEPARTMENT (604) 552 3031 November 14 2006
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