MATERIAL SAFETY DATA SHEET
SECTION 1 - PRODUCT IDENTIFICATION AND USE
PRODUCT IDENTIFICATION NUMBER (PIN):
PRODUCT IDENTIFIER
Sodium nitrite SO310X
PRODUCT USE
MANUFACTURERS NAME: SUPPLIERS NAME:
Xenex Labs XENEX LABORATORIES INC.
STREET ADDRESS: STREET ADDRESS:
2402 CANOE AVENUE
CITY: PROVINCE: CITY: PROVINCE:
COQUITLAM B.C.
POSTAL CODE: EMERGENCY TELEPHONE NO: POSTAL CODE: EMERGENCY TELEPHONE NO:
SPE100 V3K 6C2 (CHEMTREC) 1-800-424-9300
SECTION 2 - HAZARDOUS INGREDIENTS
HAZARDOUS INGREDIENTS
% CAS NUMBER LD50 / LC50 OF INGREDIENT
/ CHEMICAL FORMULA
(SPECIFY SPECIES) (SPECIFY ROUTE AND DOSE)
Sodium nitrite 100 7632-00-0 RAT ORAL 180mg/kg
NaNO2 MOUSE ORAL 175mg/kg
SECTION 3 - PHYSICAL DATA
PHYSICAL STATE AND APPEARANCE ODOR TASTE ODOR THRESHOLD (ppm)
Solid (White to slightly yellow powder) Odorless Saline (Slight) Not Available
MELTING POINT (C) BOILING POINT (C) VAPOR PRESSURE VAPOR DENSITY VOLATILITY
271掳C (519.8掳F) 320掳C (608掳F) Not Applicable Not Available Not Available
pH (1% soln/water) SPECIFIC GRAVITY COEFF. WATER/OIL DIST.
9 [Basic] 2.2 Not Available
DISPERSION PROPERTIES / SOLUBILITY
Easily soluble in hot water.
Soluble in cold water.
Partially soluble in methanol
Very slightly soluble in diethyl ether.
SECTION 4 - FIRE AND EXPLOSION DATA
NO YES
FLAMMABILITY IF YES, UNDER WHAT CONDITIONS?
Non Flammable - Slightly explosive in presence of shocks, of heat. When in contact with organic matter it will ignite by
friction. May ignite combustibles.
Explodes when heated over 1000 F (538 C).
Sodium Nitrite + thiocyanate explodes on heating.
A mixture of sodium nitrite and various cyanides explodes on contact.
Mixture of sodium nitrite and phthalic acid or anhydride explode violently on heating.
Fusion of urea with sodium nitrite must be carried out exactly as described to avoid irsk of explosion.
Interaction of nitrites when heated with metal amidosulfates (sulfamates) may become explosively violent owing to
liberation of nitrogen and steam mixed with ammonium sulfamate form.
Violent explosion occurs if an ammonium salt is is melted with nitrite salt.
Shock may explode nitrites.
MEANS OF EXTINCTION
Not Applicable
FLASHPOINT (C) AND METHOD FLAMMABLE LIMITS (% BY VOLUME) CRITICAL TEMPERATURE
Not Applicable UPPER: Not Applicable LOWER: Not Applicable Not Available
AUTOIGNITION TEMPERATURE (C) HAZARDOUS COMBUSTION PRODUCTS
Not Applicable Not Available
MATERIAL SAFETY DATA SHEET
SO310X
PRODUCT IDENTIFIER
Sodium nitrite
SECTION 5 - REACTIVITY DATA
YES NO IF NO, UNDER WHICH CONDITIONS?
CHEMICAL STABILITY
The product is stable Avoid excess heat, dust generation, ignition sources, exposure to air, combustible materials,
incompatible materials, exposure to moist air or water.
NO YES
INCOMPATIBILITY WITH OTHER SUBSTANCES IF SO, WHICH ONES?
Highly reactive with combustible materials, organic materials.
Reactive with reducing agents, metals, acids.
REACTIVITY, AND UNDER WHAT CONDITIONS
Hygroscopic.
Strong oxidizer. Slowly oxidizes to nitrate in air.
Reacts vigorously with reducing materials.
Sodium nitrite is a strong oxidizer and is incompatible with the following: acetanilide, metals as powders, ammonium
salts, aminoguanidine salts, anitpyrine, Butadiene, chlorates, hypophosphites, activated carbon, iodides, mercury salts,
permanganate, phthalic acid, phthalic anydride, sodium amide, sodium disulphite, cyanides (e.g. potassium cyanide,
sodium cyanide), sodium thiocyanate, lithium, sulfites, tannic acid, urea, wood, vegetable astringent decoctions,
infusions, or tinctures.
HAZARDOUS DECOMPOSITION PRODUCTS
possibly hazardous short term products of degradation are not likely. However long term degradation products may
arise. The products of degradation are less toxic than the product itself.
SECTION 6 - TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY
INGESTION
INHALATION
SKIN CONTACT SKIN ABSORPTION EYE CONTACT
EFFECTS OF ACUTE EXPOSURE TO PRODUCT
Very hazardous in case of ingestion. Hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation.
Slightly hazardous in case of skin contact (permeator). Prolonged exposure may result in skin burns and ulcerations.
Over-exposure by inhalation may cause respiratory irritation. Severe over-exposure can result in death.
May cause damage to the following organs: blood, cardiovascular system, Smooth Muscle.
Skin: Causes skin irritation. May be absorbed through skin.
Eyes: Causes eye irritation. May cause conjunctivitis. May cause permanent corneal opacification.
Inhalation: May cause respiratory tract irritation, cyanosis, dyspena, pulmonary edema, asphyxia, chemical
pneumonitis, upper airway obstruction caused by edema and possible death. May cause biochemical changes.
May affect the blood (methemoglobinemia), and the cardiovascular system (tachycardia).
Ingestion: Harmful if swallowed. Causes gastrointestinal tract irritation with nausea.
The primary toxic effects of nitrites include orthostatic hypotension (due to perpheral vasodilation) and
methemoglobinemia (the formation of methemoglobin in the blood which causes deficient oxygenation of the blood due
to decreased available hemoglobin). Other effects or symptoms may include flushed skin, sweating, muscular weakness,
dizziness, lightheadness, fatigue, throbbing headache, mental impairment, incoordination, loss of reflexes, change in
motor activity, seizures convulsions, coma, rapid pulse, bradycardia or tachydardia (slow or fast heart beat),
dysrhythmias, visual disturbances, dyspnea. Furthermore, methemoglobinemia due to inadequate oxygenation of the
blood can lead to progressive cyanosis, and coma. Cyanosis is first visible as a bluish discoloration of the mucous
membranes and unpigmented areas of the body. May also affect the liver, urinary system, brain
EFFECTS OF CHRONIC EXPOSURE TO PRODUCT
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.
The substance may be toxic to blood, cardiovascular system, Smooth Muscle.
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a highly
toxic material may produce general deterioration of health by an accumulation in one or many human organs.
Passes through the placental barrier in animal. May cause cancer based on animal test data.
May cause adverse reproductive effects and birth defects (teratogenic).
May affect genetic material (mutagenic)
Ingestion: Prolonged or repeated ingestion may cause nausea, vomiting, dizziness, rapid or slow heart beat,
SYNERGISTIC PRODUCTS
EXPOSURE LIMITS IRRITANCY OF PRODUCT SENSITIZATION OF PRODUCT
Not Available Yes Not Available Not Available
REPRODUCTIVE TOXICITY MUTAGENICITY
TERATOGENICITY CARCINOGENICITY
Not Available Not Available
As Specified As Specified
MATERIAL SAFETY DATA SHEET
SO310X
PRODUCT IDENTIFIER
Sodium nitrite
SECTION 7 - PREVENTATIVE MEASURE
PERSONAL PROTECTIVE EQUIPMENT
GLOVES (SPECIFY) RESPIRATOR (SPECIFY) EYE (SPECIFY)
Yes ( impervious ) Dust mask Safety goggles, face shield
FOOTWEAR (SPECIFY) CLOTHING (SPECIFY) OTHER (SPECIFY)
No Synthetic Apron Eyewash equipment nearby
ENGINEERING CONTROLS (SPECIFY eg. VENTILATION, ENCLOSED PROCESS)
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
LEAK AND SPILL PROCEDURE
Use appropriate tools to put the spilled solid in a convenient waste disposal container.
WASTE DISPOSAL
According to local, provincial, and federal regulations.
HANDLING PROCEDURES AND EQUIPMENT
Keep away from heat. Keep away from sources of ignition. Keep away from combustible material.. Do not ingest. Do not
breathe dust. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice
immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such
as reducing agents, combustible materials, organic materials, metals, acids.
STORAGE REQUIREMENTS
Oxidizer. Hygroscopic. Air sensitive. Keep container tightly closed. Keep container in a cool, well-ventilated area.
Separate from acids, alkalies, reducing agents and combustibles. See NFPA 43A, Code for the Storage of Liquid and
Solid Oxidizers. Do not store above 23掳C (73.4掳F).
Container may be hazardous when empty since they retain product residues (Dust, Solids) observe all warnings and
precautions listed for the product
SPECIAL SHIPPING INFORMATION
DOT CLASS 5.1: Oxidizing material.
CLASS 6.1: Poisonous material.
WHMIS (Canada) CLASS C: Oxidizing material.
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
CLASS D-2B: Material causing other toxic effects (TOXIC).
SECTION 8 - FIRST AID MEASURES
SPECIFIC MEASURES
Wash with soap and water. Cover the irritated skin with an emollient. Remove contaminated
SKIN
clothing and shoes. Get medical attention. Wash clothing before reuse, thoroughly clean shoes
before reuse.
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of
EYES
water for at least 15 minutes. Get medical attention immediately
If inhaled remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give
INHALATION
oxygen. Get medical attention immediately
INGESTION Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as collar, tie, belt or waistband. Get
medical attention immediately
IF IRRITATION PERSISTS AND IN ALL OTHER CASES, GET IMMEDIATE MEDICAL ATTENTION.
SECTION 9 - PREPARATION DATE OF M.S.D.S.
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packa
If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the us
responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical
data judged to be reliable, Xenex Laboratories Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
PREPARED BY (GROUP, DEPARTMENT, ETC.) PHONE NUMBER DATE:
CONTROL DEPARTMENT (604) 552 3031 April 03 2008
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