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MSDS 
:
 Carbamylcholine Chloride, 99.0-101.0% (on the Dried Substance)
CAS 
:
 51-83-2
SYNONYMS 
:
 Carbachol; (2-Hydroxyethyl)trimethylammonium Chloride Carbamate.
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 51-83-2 |CARBAMYLCHOLINE CHLORIDE | 99% | 200-127-3 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 25 36/37/38

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Toxic if swallowed. Irritating to eyes, respiratory system and
skin.Hygroscopic (absorbs moisture from the air).

Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May be fatal if swallowed. Poison by ingestion. May cause
gastrointestinal irritation with nausea, vomiting and diarrhea.
Ingestion may cause colic, constipation and weakness. Ingestion of
large amounts may cause leg cramps and muscle weakness.
Inhalation:
Causes respiratory tract irritation. Harmful if inhaled.
Chronic:
No information found.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid immediately. Call a poison control center. If swallowed, do not
induce vomiting unless directed to do so by medical personnel. Never
give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Get medical
aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased
apply artificial respiration using oxygen and a suitable mechanical
device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Dangerous
fire hazard in the form of dust when exposed to heat or flame.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Minimize dust generation and
accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in
eyes, on skin, or on clothing. Keep container tightly closed. Avoid
ingestion and inhalation. Do not ingest or inhale. Use only in a
chemical fume hood. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Store
protected from moisture.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 51-83-2:


Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Crystalline powder
Color: faint yellow - white crystalline powder
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 200-204 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >210 deg C
Solubility in water: practically insoluble in chloroform and
Specific Gravity/Density:
Molecular Formula: C6H15ClN2O2
Molecular Weight: 182.65

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Hygroscopic: absorbs moisture or water from
the air.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, exposure to
moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 51-83-2: GA0875000
LD50/LC50:
CAS# 51-83-2: Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40
mg/kg.
Carcinogenicity:
CARBAMYLCHOLINE CHLORIDE -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****



**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: II
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: II
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: II

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 25 Toxic if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 51-83-2: No information available.
Canada
CAS# 51-83-2 is listed on Canada's NDSL List.
CAS# 51-83-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 51-83-2 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

MSDS Creation Date: 5/11/1999 Revision #4 Date: 1/31/2005

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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