**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 67-63-0 |2-Propanol | | 200-661-7 |
|----------------|--------------------------------------|----------|-----------|
| 75-05-8 |Acetonitrile | | 200-835-2 |
|----------------|--------------------------------------|----------|-----------|
| 13796-58-2 |Doyle dirhodium catalyst - RH2(5R-MEPY| | unlisted |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 20/21/22 41
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. Risk
of serious damage to eyes.The toxicological properties of this
material have not been fully investigated.
Potential Health Effects
Eye:
Causes severe eye irritation and possible injury.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. The toxicological properties of this substance have not
been fully investigated.
Inhalation:
Causes respiratory tract irritation. The toxicological properties of
this substance have not been fully investigated. Exposure produces
central nervous system depression.
Chronic:
Prolonged or repeated skin contact may cause defatting and
dermatitis. Prolonged exposure may produce a narcotic effect.
Prolonged or repeated exposure may cause nausea, dizziness, and
headache.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. May form explosive peroxides. Vapors may be heavier
than air. They can spread along the ground and collect in low or
confined areas.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
In case of fire, use carbon dioxide, dry chemical powder or
appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Remove all sources of ignition. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Avoid breathing dust, vapor, mist, or
gas. Do not get on skin or in eyes. Avoid ingestion and inhalation.
Keep from contact with moist air and steam.
Storage:
Keep container closed when not in use. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Store protected from moisture.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Use explosion-proof ventilation equipment.
Facilities storing or utilizing this material should be equipped with
an eyewash facility and a safety shower.
Exposure Limits
CAS# 67-63-0:
United Kingdom, WEL - TWA: 400 ppm TWA; 999 mg/m3 TWA
United Kingdom, WEL - STEL: 500 ppm STEL; 1250 mg/m3 STEL
United States OSHA: 400 ppm TWA; 980 mg/m3 TWA
Belgium - TWA: 400 ppm VLE; 997 mg/m3 VLE
Belgium - STEL: 500 ppm VLE; 1248 mg/m3 VLE
France - VLE: 400 ppm VLE; 980 mg/m3 VLE
Germany: 200 ppm TWA; 500 mg/m3 TWA
Japan: 400 ppm Ceiling; 980 mg/m3 Ceiling
Malaysia: 400 ppm TWA; 983 mg/m3 TWA
Netherlands: 250 ppm MAC; 650 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 400 ppm VLA-ED; 998 mg/m3 VLA-ED
Spain: 500 ppm VLA-EC; 1250 mg/m3 VLA-EC
CAS# 75-05-8:
United Kingdom, WEL - TWA: 40 ppm TWA; 68 mg/m3 TWA
United Kingdom, WEL - STEL: 60 ppm STEL; 102 mg/m3 STEL
United States OSHA: 40 ppm TWA; 70 mg/m3 TWA
Belgium - TWA: 40 ppm VLE; 68 mg/m3 VLE
Belgium - STEL: 60 ppm VLE; 102 mg/m3 VLE
France - VME: 40 ppm VME; 70 mg/m3 VME
Germany: 20 ppm TWA; 34 mg/m3 TWA
Germany: Skin absorber
Malaysia: 40 ppm TWA; 67 mg/m3 TWA
Netherlands: 40 ppm MAC; 70 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 40 ppm VLA-ED; 68 mg/m3 VLA-ED
Spain: 60 ppm VLA-EC; 102 mg/m3 VLA-EC
CAS# 13796-58-2:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 258 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 258 deg C
Solubility in water: insoluble
Specific Gravity/Density:
Molecular Formula: C24H32N4O12Rh2.(C2H3N)n.(C3H8O)n
Molecular Weight:
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. This material may be
sensitive to peroxide formation.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, exposure to
moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, acids, bases, alkali
metals, perchlorates, sulfur, acid anhydrides, Isopropanol is
susceptible to autoxidation and therefore should be classified as
peroxidizable., dinitrogen tetraoxide, indium.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 67-63-0: NT8050000
CAS# 75-05-8: AL7700000
CAS# 13796-58-2 unlisted.
LD50/LC50:
CAS# 67-63-0: Draize test, rabbit, eye: 100 mg Severe; Draize test,
rabbit, eye: 10 mg Moderate; Draize test, rabbit, eye: 100 mg/24H
Moderate; Draize test, rabbit, skin: 500 mg Mild; Inhalation, mouse:
LC50 = 53000 mg/m3; Inhalation, rat: LC50 = 16000 ppm/8H; Inhalation,
rat: LC50 = 72600 mg/m3; Oral, mouse: LD50 = 3600 mg/kg; Oral, mouse:
LD50 = 3600 mg/kg; Oral, rabbit: LD50 = 6410 mg/kg; Oral, rat: LD50 =
5045 mg/kg; Oral, rat: LD50 = 5000 mg/kg; Skin, rabbit: LD50 = 12800
mg/kg.
CAS# 75-05-8: Draize test, rabbit, eye: 100 uL/24H Moderate;
Inhalation, mouse: LC50 = 2693 ppm/1H; Inhalation, rabbit: LC50 =
2828 ppm/4H; Inhalation, rat: LC50 = 7551 ppm/8H; Oral, mouse: LD50 =
269 mg/kg; Oral, rabbit: LD50 = 50 mg/kg; Oral, rat: LD50 = 2460
mg/kg; Skin, rabbit: LD50 = >2 gm/kg.
CAS# 13796-58-2.
Carcinogenicity:
2-Propanol -
Not listed by ACGIH, IARC, or NTP.
Acetonitrile -
Not listed by ACGIH, IARC, or NTP.
Doyle dirhodium catalyst - RH2(5R-MEPY)4 -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Fathead Minnow: 1020 mg/L; 96 Hr; TLm (CAS#: 75-05-8)Fish:
Fathead Minnow: 1640 mg/L; 96 Hr; Flow Through Bioassay (CAS#:
75-05-8)CAS#: 67-63-0: LC50 Pimephales promelas (fathead minnows)
11,830 mg/l/1 hr (static bioassay in Lake Superior water at 18-22 deg
C).; LC50 Pimephales promelas (fathead minnows) 9.64 g/l/96 hr (95%
confidence
limit 9.23-10.0 g/l); age 31 days old, water hardness
48.3 mg/l (CaCO3), temp 24.4 deg C, pH 7.79, dissolved oxygen 6.6
mg/l, alkalinity 45.9 mg/l (CaCO3), tank vol: 6.3 l, additions: 3.75
vol/day (flow-through bioassay).; Cell multiplication test
Scenedesmus guadricauda (green algae) 1800 mg/l.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 75-05-8: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 41 Risk of serious damage to eyes.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 67-63-0: 1
CAS# 75-05-8: 2
CAS# 13796-58-2: No information available.
Canada
CAS# 67-63-0 is listed on Canada's DSL List.
CAS# 75-05-8 is listed on Canada's DSL List.
CAS# 67-63-0 is listed on Canada's Ingredient Disclosure List.
CAS# 75-05-8 is listed on Canada's Ingredient Disclosure List.
CAS# 13796-58-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-63-0 is listed on the TSCA inventory.
CAS# 75-05-8 is listed on the TSCA inventory.
CAS# 13796-58-2 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
R 11 Highly flammable.
R 36 Irritating to eyes.
R 67 Vapours may cause drowsiness and dizziness.
MSDS Creation Date: 10/16/1997 Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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