**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 75-05-8 |Acetonitrile | 1 | 200-835-2 |
|----------------|--------------------------------------|----------|-----------|
| 185437-81-4 |Doyle dirhodium catalyst - RH2(4S-MPPI| 99 | unlisted |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 20/21/22 41
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. Risk
of serious damage to eyes.
Potential Health Effects
Eye:
Causes severe eye irritation and possible injury.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
The toxicological properties of this substance have not been fully
investigated.
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation. The
toxicological properties of this substance have not been fully
investigated.
Chronic:
Prolonged or repeated skin contact may cause defatting and
dermatitis. Prolonged exposure may produce a narcotic effect.
Prolonged or repeated exposure may cause nausea, dizziness, and
headache.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Minimize dust
generation and accumulation. Keep container tightly closed. Avoid
breathing dust. Do not get in eyes. Avoid contact with skin and
clothing.
Storage:
Store in a tightly closed container. Keep under a nitrogen blanket.
Store in a cool, dry, well-ventilated area away from incompatible
substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 75-05-8:
United Kingdom, WEL - TWA: 40 ppm TWA; 68 mg/m3 TWA
United Kingdom, WEL - STEL: 60 ppm STEL; 102 mg/m3 STEL
United States OSHA: 40 ppm TWA; 70 mg/m3 TWA
Belgium - TWA: 40 ppm VLE; 68 mg/m3 VLE
Belgium - STEL: 60 ppm VLE; 102 mg/m3 VLE
France - VME: 40 ppm VME; 70 mg/m3 VME
Germany: 20 ppm TWA; 34 mg/m3 TWA
Germany: Skin absorber
Malaysia: 40 ppm TWA; 67 mg/m3 TWA
Netherlands: 40 ppm MAC; 70 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 40 ppm VLA-ED; 68 mg/m3 VLA-ED
Spain: 60 ppm VLA-EC; 102 mg/m3 VLA-EC
CAS# 185437-81-4:
United States OSHA: 0.1 mg/m3 TWA (as Rh) (listed under Rhodium,
water insoluble compounds).
Belgium - TWA: (listed as rhodium, water insoluble compounds): 1
mg/m3 VLE (as Rh)
Spain: (listed as rhodium, water insoluble compounds): 1 mg/m3 VL
(as Rh)
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use. Follow the OSHA
respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Use a NIOSH/MSHA or
European Standard EN 149 approved respirator if
exposure limits are exceeded or if irritation or
other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystals
Color: red
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: insoluble
Specific Gravity/Density:
Molecular Formula: C60H66N10O16Rh2
Molecular Weight: 1389.05
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, rhodium/rhodium oxides.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 75-05-8: AL7700000
CAS# 185437-81-4 unlisted.
LD50/LC50:
CAS# 75-05-8: Draize test, rabbit, eye: 100 uL/24H Moderate;
Inhalation, mouse: LC50 = 2693 ppm/1H; Inhalation, rabbit: LC50 =
2828 ppm/4H; Inhalation, rat: LC50 = 7551 ppm/8H; Oral, mouse: LD50 =
269 mg/kg; Oral, rabbit: LD50 = 50 mg/kg; Oral, rat: LD50 = 2460
mg/kg; Skin, rabbit: LD50 = >2 gm/kg.
CAS# 185437-81-4.
Carcinogenicity:
Acetonitrile -
Not listed by ACGIH, IARC, or NTP.
Doyle dirhodium catalyst - RH2(4S-MPPIM)4 -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 75-05-8: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 41 Risk of serious damage to eyes.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 75-05-8: 2
CAS# 185437-81-4: No information available.
Canada
CAS# 75-05-8 is listed on Canada's DSL List.
CAS# 75-05-8 is listed on Canada's Ingredient Disclosure List.
CAS# 185437-81-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 75-05-8 is listed on the TSCA inventory.
CAS# 185437-81-4 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 3/02/1999 Revision #3 Date: 5/24/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
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2,6-Di-tert.butyl-4-methylphenol,
| 128-37-0 |
|
Sodium Hydride, 60% Dispersion in Mineral Oil, DMF Soluble Bags
| 7646-69-7 |
|
1,1,1-Trichloroacetone
| 918-00-3 |
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(m-methoxyphenyl)acetonitrile, 97%
| 19924-43-7 |
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Tributylpropynylstannane
| 64099-82-7 |
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Diethylenetriamine-n,n,n',n',n'',n''-penta acetic dianhydride
| 23911-26-4 |
|
N-boc-l-1,2,3,4-tetrahydro-beta-carboline- 3-carboxylic acid
| |
|
D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride
| 41220-48-8 |
|
2-Tert-Butylcyclohexanone, 97%
| 1728-46-7 |
|
L-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride
| 77497-95-1 |
|
4-Chloro-3-Methylphenol, 99%
| 59-50-7 |
|
N-boc-l-1,2,3,4-tetrahydroisoquinoline-3-c arboxylic acid
| |
|
N-FMOC-l-1,2,3,4-Tetrahydroisoquinoline-3- Carboxylic Acid
| 136030-33-6 |
|
N,n,2-trimethylpropionamide, 99%
| 21678-37-5 |
|
5-Amino-3-Phenyl-1,2,4-Thiadiazole, 99%
| 17467-15-1 |
|
4,6-Dimethyldibenzothiophene, 95% (gc)
| |
|
[(2-Chloroethyl)thio]benzene
| 5535-49-9 |
|
2,2-Dichlorocyclopropyl phenyl sulfide
| 63289-85-0 |
|
2,2-Dichlorocyclopropyl phenyl sulfone
| 38435-04-0 |
|
1-TOSYL-4-PHENYL-4-CARBOXY PIPERIDINE
| 50-00-0 |
|
(+)-[(8,8-Dichlorocamphoryl)sulfonyl]oxazi ridine
| 127184-05-8 |
|
(-)-[(8,8-Dichlorocamphoryl)sulfonyl]oxazi ridine
| 139628-16-3 |
|
Dl-3-aminoisobutyric acid monohydrate, 99%
| |
|
4-Phenyl-1-Butanol, 97%
| 3360-41-6 |
|
Potassium deuteroxide, 30 wt% solution in D2O
| 7789-20-0 |
|
5-tert.-Butyl-4-hydroxy-2-methylphenyl sulfide
| 96-69-5 |
|
Pyridinium fluorochromate
| 83042-08-4 |
|
5-beta-Cholestan
| 481-20-9 |
|
Dibenzoyl-d-tartaric acid
| 17026-42-5 |
|
Doyle dirhodium catalyst - RH2(5R-MEPY)4
| 67-63-0 |
|
Doyle dirhodium catalyst - RH2(5S-MEPY)4
| 67-63-0 |
|
Doyle dirhodium catalyst - rh2(4s-meox)4
| 167693-36-9 |
|
Doyle dirhodium catalyst - RH2(4S-MPPIM)4
| 75-05-8 |
|
Doyle dirhodium catalyst - rh2(capy)4
| 138984-26-6 |
|
Dibromoacetonitrile, 97+%
| 3252-43-5 |
|
Octyl Sodium Sulfate, HPLC Grade, 94% (Titr.)
| 142-31-4 |
|
Isobutyl vinyl ether, 99.5% (gc), stabilized with 0.1% potassium
| 109-53-5 |
|
Potassium hydroxide, 50 wt% aqueous solution
| 1310-58-3 |
|
Potassium hydroxide, 10 wt% aqueous soluti on
| 1310-58-3 |
|
Potassium hydroxide, 30 wt% aqueous solution
| 1310-58-3 |
|
Dl-aspartic acid k-mg salt
| |
|
1-Chloro-N,N,2-trimethylpropenylamine, 98.5+% (GC)
| 26189-59-3 |
|
Isosorbide-2-mononitrate
| 16106-20-0 |
|
1,2-Dichloroethylene, 99%, mixture of isomers
| 540-59-0 |
|
cis-1,2-Dichloroethylene, 97%
| 156-59-2 |
|
2-Methylaminophenol, 97+%
| 611-24-5 |
|
Hydrogen Peroxide, 50 wt% Solution in Water
| 7722-84-1 |
|
Ammonium Hydroxide, 25% Solution in Water, C.P.
| 1336-21-6 |
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N-(1-Naphthyl)ethylenediamine Dihydrochloride, P.A.
| 1465-25-4 |
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N-Ethyl-Beta-Alaninenitrile
| 21539-47-9 |
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