MATERIAL SAFETY DATA SHEET THALLOUS NITRATE
PRODUCT CODE NUMBER(S): 8890-1
PRODUCT IDENTIFICATION easily oxidizable, organic, or other combustible materials
may result in ignition, violent combustion or explosion. Con-
Chemical Name and Synonyms: Thallous nitrate; Thal- tainers may explode in heat of fire.
lium nitrate Extinguishing Media: Use flooding amounts of water to
Chemical Family: Thallium compounds blanket fire, cool exposed containers, and to flush solid or
Chemical Formula: TINO3 vapours away from fire. Fight fire from upwind, from a safe
distance. Firefighters must wear protective equipment (full
Product Use: Laboratory reagent
face-piece, positive-pressure self-contained breathing appa-
Manufacturer鈥檚 Name and Address:
ratus) and clothing sufficient to prevent inhalation of dusts or
Caledon Laboratories Ltd. vapours, and contact with skin and eyes.
40 Armstrong Avenue Flash Point (Method Used): Not applicable
Georgetown, Ontario L7G 4R9
Autoignition Temperature: Not applicable
Telephone No: (905) 877-0101 Upper Flammable Limit (% by volume): Not applicable
Fax No: (905) 877-6666 Lower Flammable Limit (% by volume): Not applicable
Emergency Telephone No: CANUTEC (613) 996-6666 Hazardous Combustion Products: Emits toxic fumes of
Tl, NOx when heated.
HAZARDOUS INGREDIENTS OF MATERIALS Sensitivity to Impact: None identified when pure. If con-
taminated or in contact with combustible materials may form
Ingredients % TLV Units CAS No.
shock-sensitive compounds.
0.1 mg/m3
Thallous nitrate >99 10102-45-1 Sensitivity to Static discharge: Mixtures of dust with air
(TI) may be sensitive under certain conditions, particularly when
contaminated with organic materials, when exposed to elec-
PHYSICAL DATA trostatic or other high-voltage spark, or other ignition source.
Physical State: Solid TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Odour and Appearance: White cubic crystals, odourless
Toxicological Data:
Odour Threshold (ppm): Not applicable
Vapour Pressure (mm Hg): Not available LD50: (oral, mouse) 15 mg/kg; (ipr, rat) 21mg/kg
Vapour Density (Air = 1): Not available LDLO: (oral, dog) 45 mg/kg
Evaporation Rate: Not applicable LC50: Not available
Boiling Point (degrees C): 430掳C (decomposes)
Effects of Acute Exposure to Product:
Melting Point (degrees C): 206掳C (solidifies to a glass-like
solid) Inhaled: Highly toxic. May be fatal. Causes severe irrita-
pH: Not available tion, possible damage to upper respiratory tract tissue, and
systemic poisoning with nausea, abdominal pain, vomiting,
Specific Gravity: 5.55
weakness of limbs, hypermotility and mental confusion.
Coefficient of Water/Oil distribution: Not available
Acute poisoning leads to CNS damage, respiratory failure,
and death in 10-12 days. At high temperatures, exposure to
SHIPPING DESCRIPTION toxic nitrogen oxides decomposition products can quickly
cause acute respiratory problems. Absorption leads to sys-
UN: 2727
temic poisoning with headache, fall in blood pressure, the
T.D.G. Class: 6.1
formation of methemoglobin which decreases the ability of
Pkg. Group: II the blood to carry oxygen, causing cyanosis, possible con-
vulsions, coma, and death. Onset may be delayed 2 to 4
REACTIVITY DATA hours or longer.
In contact with skin: May cause severe irritation. Readily
Chemical Stability: Stable, hygroscopic
absorbed through skin, causing nausea, abdominal pain,
Incompatibility with other substances: May react vio- vomiting, diarrhea, weakness of limbs and mental confusion.
lently or explosively with strong reducing agents, strong May be fatal by skin absoprtion.
acids, combustible materials, powdered metals, cyanides, In contact with eyes: May cause severe irritation, burns
thiocyanates, isothiocyanates, hypophosphites. Mixtures and possible corneal damage.
with aluminum and water, with alkyl esters, with phosphorus,
Ingested: May be fatal if swallowed. Acute poisoning
tin(2) chloride or other reducing agents may explode.
causes nausea and vomiting, diarrhea, swelling of the legs
Reactivity: May explode if exposed to heat, shock, friction. and feet, insomnia, mental confusion, hypermotility, convul-
Avoid all incompatible materials, ignition sources, combusti- sions, and collapse. May cause methemoglobinemia and
ble materials, generation of dust. cyanosis (see 鈥淚nhaled鈥?).
Hazardous Decomposition Products: Nitrogen oxides
Effects of Chronic Exposure to Product:
FIRE AND EXPLOSION DATA
Danger of cumulative, irreversible effects. Exposure to
Flammability: Not combustible but strong oxidizer. Will in- small amounts of dust or solution over a long period may re-
crease the burning rate of combustible matter. Contact with sult in loss of appetite, hair loss, pain or weakness of limbs
THALLOUS NITRATE
MSDS
CODE: 8890-1
leading to paralysis, insomnia, ataxia, tremor, of non-combustible materials. Keep away from all ignition sources.
Keep containers tightly closed when not in use and when empty.
incoordination, endocrine disorders, and mental distur-
Protect from damage, and inspect frequently for signs of leaking;
bances, nervousness, irritablity, anxiety, depression.
unattended spillage onto combustible materials (wood, paper, etc.)
Chronic overexposure to nitrates can lead to
could result in fire.
methemoglobinemia (see 鈥淚nhaled鈥?), and conversion of ni-
trate to nitrite in the stomach, causing nausea and vomiting,
FIRST AID MEASURES
blood and central nervous system effects, weakness, de-
pression, headache, irregular heart rate; severe Specific Measures:
overexposure can cause coma and death.
In all cases of thallium compound exposure, take the container or
Carcinogenicity: Not listed as a carcinogen.
label to the physician when possible.
Teratogenicity: No information available
Note to physician: Prussian Blue (potassium ferric
Reproductive Effects: No information available
hexacyanoferrate(II) is a specific antidote for Thallium poisoning.
Mutagenicity: No information available The K ion replaces the Tl ion preventing the absorption of toxic Tl;
the resulting chemcial is excreted in the feces. A dose of 10 g,
Synergistic Products: None known
twice a day should be given intraduodenally in 100 mg of 15%
PREVENTIVE MEASURES mannitol as a laxative. Daily defecation is essential.
Eyes: Immediately flush eyes with gently running water or normal
Engineering Controls: Local exhaust ventilation required saline for at least thirty (30) minutes, holding eyelids open during
Respiratory Protection: Use only in a fume hood. Wear flushing. Wear protective gloves to prevent contact during first aid
NIOSH/MSHA approved dust mask. NIOSH/MSHA ap- procedures. Take care not to flush contaminated water into unaf-
proved full face-piece supplied-air respirator for exposures fected eye. Get medical attention IMMEDIATELY.
exceeding TLV. For higher or unknown concentrations, as Skin: Remove contaminated clothing, including watches, rings,
in fire or spill conditions, full face-piece, positive-pressure belts, and shoes. Flush affected areas with soap and copious
self-contained breathing apparatus or full face-piece sup- amounts of running water for at least thirty (30) minutes. Get medi-
plied-air respirator with auxiliary positive-pressure cal advice IMMEDIATELY. Wash or discard contaminated clothing
self-contained breathing apparatus. before reuse. Be aware that clothing may become dangerously
Eye Protection: Chemical safety goggles and/or face flammable after contact with this chemical.
shield. Inhalation: Move victim to fresh air. Give oxygen and get medical
Skin Protection: Impervious gloves. Other impervious attention for any breathing difficulty. Give artificial respiration if
protective clothing, apron, sleeves, coveralls, boots suffi- breathing has stopped. Obtain medical attention IMMEDIATELY.
cient to prevent any contact. Ingestion: If victim is alert and not convulsing, give 2 to 4 glasses
Other Personal Protective Equipment: Safety shower of water to drink to dilute material. DO NOT induce vomiting. If
and eye-wash fountain in work area. spontaneous vomiting occurs, have victim lean forward with head
down to avoid breathing in of vomitus, rinse mouth and administer
Leak and Spill Procedure: Restrict access to area of spill.
more water. Obtain medical attention IMMEDIATELY.
Eliminate all sources of ignition and combustible materials.
Cleanup personnel must be thoroughly trained in the haz-
REFERENCES USED
ards of this chemical and its safe use, and must wear
protective equipment and clothing sufficient to prevent inha-
World Health Organization: Geneva 1996, T hallium and thallium
lation of dust or fumes, and contact with skin and eyes.
compounds: (Health and safety guide; no. 102
Wet if necessary to avoid generating dust. Prevent from en-
Budavari: The Merck Index, 12th ed., 1997
tering sewers and waterways. Contain spill with inert
material (earth, sand, inert absorbent). Use non-sparking Royal Society of Chemistry: Chemcial Safety Data Sheets, Vol. 2,
tools to collect material, in suitable, labelled, covered con- 1989
tainers for disposal. Contaminated absorbent may pose the
Sax, Lewis: Hawley鈥檚 Condensed Chemical Dictionary, 11th ed.,
same hazards as the chemical; treat with caution. Flush
1987
area of spill with large amounts of running water.
Sax: Dangerous Properties of Industrial Materials, 5th ed., 1979
Waste Disposal: Follow all federal, provincial and local
regulations for disposal. Suppliers鈥? Material Safety Data Sheets
Handling Procedures and Equipment: OXIDIZER. POS-
ADDITIONAL INFORMATION
SIBLE CARCINOGEN, SENSITIZER. Workers using this
chemical must be thoroughly trained in its hazards and its
Date Issued: July 15, 1991
safe use, and must wear appropriate protectiv equipment
and clothing. Keep away from combustible or organic mate- Revision: June 2006
rials, and all sources of ignition. Use non-sparking tools. MSDS: 8890-1
Avoid all contact and inhalation. Do not shock. Use the
Proposed WHMIS Designation: C; D1A; D2A
smallest amount possible for the purpose, in designated ar-
eas with adequate ventilation. Keep work area clean and
Prepared by: Caledon Laboratories Ltd. (905) 877-0101
free of extraneous, particularly combustible, materials. Do
Caledon Laboratories Ltd. believes the information contained herein
not use on porous surfaces (wood); use surfaces that can
be easily and thoroughly cleaned. Clean up spills immedi- is reliable and accurate. Caledon makes no warranty with respect
ately and thoroughly. Keep containers closed when not in thereto and expressly disclaims all liability for reliance thereon. Such
use and when empty. Empty containers may contain haz- information is solely for your consideration, investigation, and verifi-
ardous residues; treat with caution. Wash hands thoroughly cation.
after use.
Storage Requirements: Store in suitable, labelled contain-
ers, in a cool, dry, well-ventilated area, out of direct sunlight,
and away from incompatible, combustible or organic materi-
als. Storage facilities (shelves, floors) should be constructed
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