MATERIAL SAFETY DATA SHEET
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Product: BCP Phase Separation Reagent
Cat. No: BP 151
Molecular Research Center, Inc.
5645 Montgomery Rd.
Cincinnati, Ohio 45212
USA 1-888-841-0090
Product Name: BCP Phase Separation Reagent
Chemical Formula: C3H6BrCl
Molecular Weight: 157.44
Synonyms: 3-bromopropyl chloride; omega-chlorobromopropane; 1-chloro-3-bromopropane (DOT); 3-chloropropyl
bromide.
NFPA RATINGS: Health=2 Fire=1 Reactivity=0
HMIS RATINGS: (scale 0-4) Health=2 Fire=2 Reactivity=0 PPE=H
CHEMTREC EMERGENCY NUMBER 1-703-527-3887
2. COMPOSITION / INFORMATION ON INGREDIENTS
Component CAS No Percent
1-Bromo-3-Chloropropane 109-70-6 100%
EINECS No.
203-697-1
3. HAZARD IDENTIFICATION
ROUTES OF EXPOSURE: Skin Yes
Ingestion Yes
Inhalation Yes
ACUTE EFFECTS: Harmful if inhaled or swallowed. Chemical permeator causing eye and skin irritation. Material is
irritating to mucous membranes and upper respiratory tract and can result in dizziness and headache. Ingestion may
cause gastrointestinal irritation with nausea, vomiting and diarrhea with potential liver and kidney damage.
4. FIRST AID
EYE CONTACT: Check for and remove any contact lenses. Flush eyes with water for 15 min., holding eyelids open.
Obtain medical attention.
SKIN CONTACT: Flush skin with soap and water for 15 min. Remove contaminated clothing and thoroughly wash
before reuse. Cover the irritated skin with an emollient.
INHALATION: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. Obtain
medical attention.
INGESTION: If swallowed, wash mouth out if person is conscious. Do not induce vomiting unless directed so by
medical personnel. Obtain medical attention. Loosen tight clothing such as a collar, tie belt or waistband.
5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA: May be combustible at high temperatures. Extinguishing media appropriate to
surrounding fire conditions. Small Fire: Use dry chemical powder. Large Fire: Use water spray, fog or foam. Do not use
water jet. Emits toxic fumes under fire conditions (chloride, bromide).
SPECIAL FIRE FIGHTING PROCEDURES: Wear self-contained breathing apparatus and protective clothing to
prevent contact with skin and eyes.
6. ACCIDENTAL RELEASE MEASURES
PERSONAL PROTECTIVE EQUIPMENT FOR SPILL CONDITIONS: Note that accidental releases may be
subject to special reporting requirements and other regulatory mandates. Check and comply with local laws and
regulations. Use gloves and other appropriate protective covering to avoid skin contact. Ensure adequate ventilation.
Use goggles, face shield or other eye protection. Contain spill with an inert adsorbent such as vermiculite, sand or earth.
Place spill material in a suitable container and hold for disposal. Avoid breathing vapor, mist or gas.
7. HANDLING AND STORAGE
Store in a cool, dry place in sealed containers. Ensure good ventilation at the workplace. Practice good laboratory
techniques when handling this substance. After using the chemical, wash hands thoroughly. Use adequate ventilation
and avoid breathing vapor, mist or gas. Empty containers pose a fire risk and any residue should be evaporated under a
fume hood. Keep away from incompatibles such as oxidizing agents, metals and alkalis.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
For routine operations wear safety glasses, latex gloves and a chemical apron to avoid contact with eyes, skin and
clothing. Facilities utilizing this chemical should be equipped with an eyewash station and safety shower. Use adequate
ventilation to keep airborne concentrations below the permissible exposure limits. (No PELS are listed for this
chemical).
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear, colorless liquid
Odor: Chloroform-like- sweetish odor
Vapor Pressure: 6.6 mbar @ 20 C
Density: 1.5920
Boiling point: 144 B 145 C
Melting point: - 59 C
Flash point: Closed Cup 45 C (113 F)
Solubility in water: Insoluble
Specific gravity: 1.592 (water=1)
Solubility: Insoluble in cold water, hot water.
10. STABILITY AND REACTIVITY
Stable under normal temperatures and pressures.
INCOMPATIBILITIES: Heat, ignition sources, strong bases, strong oxidizing agents, magnesium, zinc, aluminum.
DECOMBUSTION PRODUCTS: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide, and hydrogen
bromide gas.
11. TOXICOLOGICAL INFORMATION
RTECS# TX4113000 DOT: POISON B, 6.1, III
Rat: Inhalation: LC50=5668 mg/m3; oral LD50=930 mg/kg; Mouse: oral LD50=1290 mg/kg. LCLo/2H: 7270 mg/m3.
CARCINOGENICITY: Not listed by ACGIH, NIOSH, NTP OR OSHA.TARGET ORGAN DATA.
To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
12. ECOLOGICAL INFORMATION
ECOTOXICITY: LC50 (24 hr) goldfish 75 mg/l.
Possibly hazardous short-term degradation products are not likely; however, long-term degradation products are possible.
The products of degradation are as toxic as the product itself.
13. DISPOSAL CONSIDERATIONS
Keep in sealed containers until final disposal. Dispose of in a manner consistent with federal, state and local regulations.
Not listed as banned from land disposal according to RCRA.
14. TRANSPORT INFORMATION
IATA, IMO, RID/ADR:
Shipping Name: 1-Bromo-3-Chloropropane
Hazard Class DOT: 6.1 poisonous material
UN Number: 2688
Packing Group: III
Danger code (Kemler): 60
15. REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN Harmful
Risk Phrases:
R20/22 Harmful by inhalation and if swallowed.
R36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
9 Keep container in a well-ventilated place.
26 In case of eye contact, rinse immediately with plenty of water and seek medical advice.
36 Wear suitable protective clothing.
60 This material and its container must be disposed of as hazardous waste.
WGK (Water Danger/ Protection) CAS # 109-70-6: 3
United Kingdom Occupational Exposure Limits
Canada: CAS# 109-70-6 is listed in Canada鈥檚 DSL List and Ingredient Disclosure List
Exposure Limits: CAS# 109-70-6: OEL-Russia :STEL 3 mg/m3 US Federal
TSCA: CAS # 109-70-6 is listed on the TSCA 8(b) inventory.
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
16. OTHER INFORMATION
Reviewed by BW, MJ
Revision date 5/01/07
This information is believed to be accurate and represents the information currently available to us. However, we make
no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.
Abbreviations:
N/A Not Applicable
N.D.A. No data available
TLV-STEL Threshold Limit Values (Short-Term Exposure Limit)
TLV-TWA Threshold Limit Values (Time-Weighted Average)
OSHA PEL-TWA OSHA Permissible Exposure Level
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