TOLUENE http://www.jtbaker.com/msds/T3913.htm
TOLUENE
MSDS Number: T3913 --- Effective Date: 11/02/01
1. Product Identification
Synonyms: Methylbenzene; Toluol; Phenylmethane
CAS No.: 108-88-3
Molecular Weight: 92.14
Chemical Formula: C6H5-CH3
Product Codes: J.T. Baker: 5375, 5584, 5809, 5812, 9336, 9351, 9364, 9456, 9457, 9459,
9460, 9462, 9466, 9472, 9476
Mallinckrodt: 4483, 8091, 8092, 8604, 8608, 8610, 8611, V560
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------
Toluene 108-88-3 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF
INHALED OR ABSORBED THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE
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LIQUID AND VAPOR. MAY AFFECT LIVER, KIDNEYS, BLOOD SYSTEM, OR
CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation may cause irritation of the upper respiratory tract. Symptoms of overexposure may
include fatigue, confusion, headache, dizziness and drowsiness. Peculiar skin sensations (e. g. pins
and needles) or numbness may be produced. Very high concentrations may cause unconsciousness
and death.
Ingestion:
Swallowing may cause abdominal spasms and other symptoms that parallel over-exposure from
inhalation. Aspiration of material into the lungs can cause chemical pneumonitis, which may be fatal.
Skin Contact:
Causes irritation. May be absorbed through skin.
Eye Contact:
Causes severe eye irritation with redness and pain.
Chronic Exposure:
Reports of chronic poisoning describe anemia, decreased blood cell count and bone marrow
hypoplasia. Liver and kidney damage may occur. Repeated or prolonged contact has a defatting
action, causing drying, redness, dermatitis. Exposure to toluene may affect the developing fetus.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or impaired liver or kidney function may be more
susceptible to the effects of this substance. Alcoholic beverage consumption can enhance the toxic
effects of this substance.
4. First Aid Measures
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. CALL A PHYSICIAN IMMEDIATELY.
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Ingestion:
Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water.
Never give anything by mouth to an unconscious person. Get medical attention immediately. If
vomiting occurs, keep head below hips to prevent aspiration into lungs.
Skin Contact:
In case of contact, immediately flush skin with plenty of soap and water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse. Call a physician
immediately.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: 7C (45F) CC
Autoignition temperature: 422C (792F)
Flammable limits in air % by volume:
lel: 3.3; uel: 19
Flammable liquid and vapor!
Dangerous fire hazard when exposed to heat or flame. Vapors can flow along surfaces to distant
ignition source and flash back.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Contact
with strong oxidizers may cause fire or explosion. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water may be used to flush spills away from exposures and
to dilute spills to non-flammable mixtures.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing
apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Water spray may be used to keep fire exposed containers cool.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective
equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected
personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g.,
vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible
materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray
to disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from
exposures. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in
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excess of reportable quantities. The toll free number for the US Coast Guard National Response
Center is (800) 424-8802.
J. T. Baker SOLUSORB庐 solvent adsorbent is recommended for spills of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area
where the fire hazard may be acute. Outside or detached storage is preferred. Separate from
incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment,
including explosion proof ventilation. Containers of this material may be hazardous when empty
since they retain product residues (vapors, liquid); observe all warnings and precautions listed for
the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Toluene:
- OSHA Permissible Exposure Limit (PEL):
200 ppm (TWA); 300 ppm (acceptable ceiling conc.); 500 ppm (maximum conc.).
- ACGIH Threshold Limit Value (TLV):
50 ppm (TWA) skin, A4 - Not Classifiable as a Human Carcinogen.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the
Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended
Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a half-face organic vapor
respirator may be worn for up to ten times the exposure limit, or the maximum use concentration
specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A
full-face piece organic vapor respirator may be worn up to 50 times the exposure limit, or the
maximum use concentration specified by the appropriate regulatory agency or respirator supplier,
whichever is lowest. For emergencies or instances where the exposure levels are not known, use a
full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do
not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash
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fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Aromatic benzene-like.
Solubility:
0.05 gm/100gm water @ 20C (68F).
Specific Gravity:
0.86 @ 20C / 4 C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
111C (232F)
Melting Point:
-95C (-139F)
Vapor Density (Air=1):
3.14
Vapor Pressure (mm Hg):
22 @ 20C (68F)
Evaporation Rate (BuAc=1):
2.24
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Containers may burst when heated.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Heat, flame, strong oxidizers, nitric and sulfuric acids, chlorine, nitrogen tetraoxide; will attack some
forms of plastics, rubber, coatings.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
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11. Toxicological Information
Toxicological Data:
Oral rat LD50: 636 mg/kg; skin rabbit LD50: 14100 uL/kg; inhalation rat LC50: 49 gm/m3/4H;
Irritation data: skin rabbit, 500 mg, Moderate; eye rabbit, 2 mg/24H, Severe. Investigated as a
tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
Has shown some evidence of reproductive effects in laboratory animals.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Toluene (108-88-3) No No 3
12. Ecological Information
Environmental Fate:
When released into the soil, this material may evaporate to a moderate extent. When released into
the soil, this material is expected to leach into groundwater. When released into the soil, this material
may biodegrade to a moderate extent. When released into water, this material may evaporate to a
moderate extent. When released into water, this material may biodegrade to a moderate extent.
When released into the air, this material may be moderately degraded by reaction with
photochemically produced hydroxyl radicals. When released into the air, this material is expected to
have a half-life of less than 1 day. This material is not expected to significantly bioaccumulate. This
material has a log octanol-water partition coefficient of less than 3.0. Bioconcentration factor = 13.2
(eels).
Environmental Toxicity:
This material is expected to be toxic to aquatic life. The LC50/96-hour values for fish are between
10 and 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and
sent to a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing,
use or contamination of this product may change the waste management options. State and local
disposal regulations may differ from federal disposal regulations. Dispose of container and unused
contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
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-----------------------
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported for product/size: 390LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported for product/size: 390LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Toluene (108-88-3) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Toluene (108-88-3) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Toluene (108-88-3) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Toluene (108-88-3) 1000 U220 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
Australian Hazchem Code: 3[Y]E
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Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning:
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED
OR ABSORBED THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND
VAPOR. MAY AFFECT LIVER, KIDNEYS, BLOOD SYSTEM, OR CENTRAL NERVOUS
SYSTEM. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Label Precautions:
Keep away from heat, sparks and flame.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Avoid breathing vapor.
Avoid contact with eyes, skin and clothing.
Label First Aid:
Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water.
Never give anything by mouth to an unconscious person. If vomiting occurs, keep head below hips
to prevent aspiration into lungs. If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin
with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash
clothing before reuse. In all cases call a physician immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8.
Disclaimer:
*****************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but
makes no representation as to its comprehensiveness or accuracy. This document is
intended only as a guide to the appropriate precautionary handling of the material by a
properly trained person using this product. Individuals receiving the information must
exercise their independent judgment in determining its appropriateness for a particular
purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR
WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT
LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH
HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE
FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
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INFORMATION.
*****************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
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