TRICHLOROETHYLENE http://www.jtbaker.com/msds/T4940.htm
TRICHLOROETHYLENE
MSDS Number: T4940 --- Effective Date: 09/14/00
1. Product Identification
Synonyms: Trichloroethene; TCE; acetylene trichloride; Ethinyl trichloride
CAS No.: 79-01-6
Molecular Weight: 131.39
Chemical Formula: C2HCl3
Product Codes:
J.T. Baker: 5376, 9454, 9458, 9464, 9473, 9474
Mallinckrodt: 8598, 8600, 8633
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Trichloroethylene 79-01-6 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED OR INHALED. AFFECTS HEART,
CENTRAL NERVOUS SYSTEM, LIVER AND KIDNEYS. CAUSES SEVERE SKIN
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IRRITATION. CAUSES IRRITATION TO EYES AND RESPIRATORY TRACT.
SUSPECT CANCER HAZARD. MAY CAUSE CANCER. Risk of cancer depends on
level and duration of exposure.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD;
PROPER GLOVES
Storage Color Code: Blue (Health)
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Potential Health Effects
----------------------------------
Inhalation:
Vapors can irritate the respiratory tract. Causes depression of the central nervous system with
symptoms of visual disturbances and mental confusion, incoordination, headache, nausea, euphoria,
and dizziness. Inhalation of high concentrations could cause unconsciousness, heart effects, liver
effects, kidney effects, and death.
Ingestion:
Cases irritation to gastrointestinal tract. May also cause effects similar to inhalation. May cause
coughing, abdominal pain, diarrhea, dizziness, pulmonary edema, unconsciousness. Kidney failure
can result in severe cases. Estimated fatal dose is 3-5 ml/kg.
Skin Contact:
Cause irritation, redness and pain. Can cause blistering. Continued skin contact has a defatting
action and can produce rough, dry, red skin resulting in secondary infection.
Eye Contact:
Vapors may cause severe irritation with redness and pain. Splashes may cause eye damage.
Chronic Exposure:
Chronic exposures may cause liver, kidney, central nervous system, and peripheral nervous system
effects. Workers chronically exposed may exhibit central nervous system depression, intolerance to
alcohol, and increased cardiac output. This material is linked to mutagenic effects in humans. This
material is also a suspect carcinogen.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders, cardiovascular disorders, impaired liver or kidney or
respiratory function, or central or peripheral nervous system disorders may be more susceptible to
the effects of the substance.
4. First Aid Measures
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Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Call a physician.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an
unconscious person. Call a physician.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly
clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
Note to Physician:
Do not administer adrenaline or epinephrine to a victim of chlorinated solvent poisoning.
5. Fire Fighting Measures
Fire:
Autoignition temperature: 420C (788F)
Flammable limits in air % by volume:
lel: 8; uel: 12.5
Explosion:
A strong ignition source, e. g., a welding torch, can produce ignition. Sealed containers may rupture
when heated.
Fire Extinguishing Media:
Use water spray to keep fire exposed containers cool. If substance does ignite, use CO2, dry
chemical or foam.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing
apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Combustion by-products include phosgene and hydrogen chloride gases. Structural firefighters'
clothing provides only limited protection to the combustion products of this material.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective
equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected
personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g.,
vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible
materials, such as saw dust. Do not flush to sewer! US Regulations (CERCLA) require reporting
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spills and releases to soil, water and air in excess of reportable quantities. The toll free number for
the US Coast Guard National Response Center is (800) 424-8802.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical
damage. Isolate from any source of heat or ignition. Isolate from incompatible substances.
Containers of this material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Trichloroethylene:
-OSHA Permissible Exposure Limit (PEL):
100 ppm (TWA), 200 ppm (Ceiling),
300 ppm/5min/2hr (Max)
-ACGIH Threshold Limit Value (TLV):
50 ppm (TWA) 100 ppm (STEL);
listed as A5, not suspected as a human carcinogen.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the
Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended
Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, wear a supplied air,
full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus.
Breathing air quality must meet the requirements of the OSHA respiratory protection standard
(29CFR1910.134). This substance has poor warning properties. Where respirators are required,
you must have a written program covering the basic requirements in the OSHA respirator standard.
These include training, fit testing, medical approval, cleaning, maintenance, cartridge change
schedules, etc. See 29CFR1910.134 for details.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact. Neoprene is a recommended material for personal protective
equipment.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash
fountain and quick-drench facilities in work area.
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9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Chloroform-like odor.
Solubility:
Practically insoluble in water. Readily miscible in organic solvents.
Specific Gravity:
1.47 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
87C (189F)
Melting Point:
-73C (-99F)
Vapor Density (Air=1):
4.5
Vapor Pressure (mm Hg):
57.8 @ 20C (68F)
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Will slowly decompose to hydrochloric acid
when exposed to light and moisture.
Hazardous Decomposition Products:
May produce carbon monoxide, carbon dioxide, hydrogen chloride and phosgene when heated to
decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong caustics and alkalis, strong oxidizers, chemically active metals, such as barium, lithium,
sodium, magnesium, titanium and beryllium, liquid oxygen.
Conditions to Avoid:
Heat, flame, ignition sources, light, moisture, incompatibles
11. Toxicological Information
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Toxicological Data:
Trichloroethylene: Oral rat LD50: 5650 mg/kg; investigated as a tumorigen, mutagen, reproductive
effector.
Reproductive Toxicity:
This material has been linked to mutagenic effects in humans.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Trichloroethylene (79-01-6) No Yes 2A
12. Ecological Information
Environmental Fate:
When released into the soil, this material may leach into groundwater. When released into the soil,
this material is expected to quickly evaporate. When released to water, this material is expected to
quickly evaporate. This material has an experimentally-determined bioconcentration factor (BCF) of
less than 100. This material is not expected to significantly bioaccumulate. When released into the
air, this material may be moderately degraded by reaction with photochemically produced hydroxyl
radicals. When released into the air, this material is expected to have a half-life between 1 and 10
days.
Environmental Toxicity:
The LC50/96-hour values for fish are between 10 and 100 mg/l. This material is expected to be
slightly toxic to aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and
sent to a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing,
use or contamination of this product may change the waste management options. State and local
disposal regulations may differ from federal disposal regulations. Dispose of container and unused
contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: TRICHLOROETHYLENE
Hazard Class: 6.1
UN/NA: UN1710
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Packing Group: III
Information reported for product/size: 5GL
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: TRICHLOROETHYLENE
Hazard Class: 6.1
UN/NA: UN1710
Packing Group: III
Information reported for product/size: 5GL
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: TRICHLOROETHYLENE
Hazard Class: 6.1
UN/NA: UN1710
Packing Group: III
Information reported for product/size: 5GL
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Trichloroethylene (79-01-6) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Trichloroethylene (79-01-6) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Trichloroethylene (79-01-6) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Trichloroethylene (79-01-6) 100 U228 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Liquid)
WARNING:
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THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE CANCER.
Australian Hazchem Code: No information found.
Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED OR INHALED. AFFECTS HEART, CENTRAL
NERVOUS SYSTEM, LIVER AND KIDNEYS. CAUSES SEVERE SKIN IRRITATION.
CAUSES IRRITATION TO EYES AND RESPIRATORY TRACT. SUSPECT CANCER
HAZARD. MAY CAUSE CANCER. Risk of cancer depends on level and duration of exposure.
Label Precautions:
Do not get in eyes, on skin, or on clothing.
Do not breathe vapor.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat and flame.
Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything
by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin
with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash
clothing before reuse. In all cases call a physician. Note to physician: Do not administer adrenaline
or epinephrine to a victim of chlorinated solvent poisoning.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8, 11.
Disclaimer:
*****************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but
makes no representation as to its comprehensiveness or accuracy. This document is
intended only as a guide to the appropriate precautionary handling of the material by a
properly trained person using this product. Individuals receiving the information must
exercise their independent judgment in determining its appropriateness for a particular
purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR
WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT
LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
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PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH
HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE
FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
*****************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)
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