MATERIAL SAFETY DATA SHEET
In Case of Emergency, Call
: 1-800-888-8372
Novartis Crop Protection, Inc Novartis
Post Office Box 18300 CHEMTREC : 1-800-424-9300
Greensboro, NC 27419
1. CHEMICAL IDENTIFICATION
MEDALLION Product No.: A-7850 A
Product Name:
EPA Signal Word: Caution
Fludioxonil (50%) CAS No.: 131341-86-1
Active Ingredient(%):
4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile
Chemical Name:
Chemical Class: Substituted Benzodioxalcarbonitrile Fungicide
2. COMPOSITION/INFORMATION ON INGREDIENTS
NTP/IARC/OSHA
ACGIH
OSHA
TLV Other Carcinogen
PEL
Material
Surfactant Not Established Not Established Not Established No
Sodium Sulfate Not Established Not Established 15 mg/m3 (Total No
Dust)
Dispersing Agent 15 mg/m3 (Total Dust) 10 mg/m3 (Total Dust) Not Established No
Solid Diluent 20 mppcf (containing <1% 2 mg/m3 2 mg/m3 No
quartz) (Respirable)**
Crystalline Silica, Quartz 10 mg/m3/%SiO2+2 0.1 mg/m3 (Respirable) Not Established IARC, 2A
(Respirable)
Wetting Agent Not Established Not Established Not Established No
Fludioxonil (50%) Not Established Not Established Not Established No
** recommended by NIOSH
3. HAZARDS IDENTIFICATION
Notes to Physician
There is no specific antidote if this product is ingested.
If a large amount has been ingested and emesis is inadequate, lavage stomach.
Treat symptomatically.
Symptoms of Acute Exposure
Exposure can result in slight eye or skin irritation.
Hazardous Decomposition Products
None Known
Physical Properties
Appearance: Off-White Powder
Odor: Sweet, Soap-Like
Unusual Fire, Explosion and Reactivity Hazards
None Known
Product Name: Page: 1
MEDALLION
4. FIRST AID MEASURES
If poisoning is suspected, immediately contact a physician, the nearest hospital, or the nearest Poison Control Center. Tell the
person contacted the complete product name, and the type and amount of exposure. Describe any symptoms and follow the
advice given.
If victim is fully conscious, give large quantities of water to drink and induce vomiting. Never give anything
Ingestion:
by mouth to an unconscious person.
Immediately rinse eyes with a large amount of running water. Hold eye lids apart to rinse the entire surface
Eye Contact:
of the eyes and lids. Do not apply any medicating agents except on the advice of a physician.
Skin Contact: Wash with plenty of soap and water, including hair and under fingernails. Do not apply any medicating
agents except on the advice of a physician. Remove contaminated clothing and decontaminate prior to use.
Move victim from contaminated area to fresh air. Apply artificial respiration if necessary.
Inhalation:
Notes to Physician
There is no specific antidote if this product is ingested.
If a large amount has been ingested and emesis is inadequate, lavage stomach.
Treat symptomatically.
Medical Condition Likely to be Aggravated by Exposure
None Known
5. FIRE FIGHTING MEASURES
Fire and Explosion
Not Applicable
Flash Point (Test Method):
Flammable Limits (% in Air): Lower: %; Upper: % Not Applicable
Autoignition Temperature: Not Available
Flammability: Not Flammable
Unusual Fire, Explosion and Reactivity Hazards
None Known
In Case of Fire
Use dry chemical, foam, or CO2 extinguishing media. Wear full protective clothing and self-contained breathing
apparatus. Evacuate nonessential personnel from the area to prevent human exposure to fire, smoke, fumes or products of
combustion. Prevent use of contaminated buildings, area, and equipment until decontaminated.
6. ACCIDENTAL RELEASE MEASURES
In Case of Spill or Leak
Wear chemical safety glasses with side shields or chemical goggles, rubber gloves, rubber boots, long-sleeved shirt, long
pants, head covering, and use a particulate filter, NIOSH approved per 42 CFR Part 84. Select N or R or P type as
appropriate for the oil characteristics of any other air contaminants present. Filter efficiency may range from 95 - 99.97%
as appropriate for the size distribution of dusts present. For small spills, sweep up, keeping dust to a minimum, and place
in an approved chemical container. Wash the spill area with water containing a strong detergent, absorb with pet litter or
other absorbent material, sweep up and place in a chemical container. Seal the container and handle in an approved
manner. Flush the area with water to remove any residue. Do not allow wash water to contaminate water supplies.
7. HANDLING AND STORAGE
Store the material in a well-ventilated, secure area out of the reach of children and domestic animals. Do not store food,
beverages or tobacco products in the storage area. Prevent eating, drinking, tobacco usage, and cosmetic application in areas
where there is a potential for exposure to the material. Always wash thoroughly after handling.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
RECOMMENDATIONS FOR MANUFACTURING, COMMERCIAL BLENDING, AND PACKAGING WORKERS.
Product Name: Page: 2
MEDALLION
Prevent eating, drinking, tobacco usage and cosmetic application in areas where there is a potential for
Ingestion:
exposure to the material. Always wash thoroughly after handling.
To avoid eye contact, wear safety glasses with side shields or chemical goggles.
Eye Contact:
Skin Contact: To avoid skin contact, wear rubber gloves, rubber boots, long-sleeved shirt, long pants and a head covering.
To avoid breathing dust, use a particulate filter, NIOSH approved per 42 CFR Part 84. Select N or R or P
Inhalation:
type as appropriate for the oil characteristics of any other air contaminants present. Filter efficiency may
range from 95 - 99.97% as appropriate for the size distribution of dusts present.
Applicators/Handlers: Please refer to the product label for personal protective clothing/equipment.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Off-White Powder
Odor: Sweet, Soap-Like
Melting Point: 199.8掳C
Boiling Point: Not Applicable
Specific Gravity/Density: 0.37 g/cc
8-9(1% solution in H2O @ 25掳C)
pH:
Solubility in H2O
: 1.8 mg/L @ 25掳C
Fludioxonil
Vapor Pressure
: 3.90E-04 mPA @ 25掳C
Fludioxonil
10. STABILITY AND REACTIVITY
Reactivity
Stability: Stable
Hazardous Polymerization: Will Not Occur
Conditions to Avoid: None Known
Hazardous Decomposition Products
None Known
11. TOXICOLOGICAL INFORMATION
Acute Toxicity/Irritation Studies
Ingestion: practically non-toxic
Oral LD50 (Rat) : > 5,050 mg/kg body weight
Dermal: slightly toxic
> 2,020 mg/kg body weight
Dermal LD50 (Rabbit) :
Inhalation: practically non-toxic
> 6.5 mg/l air - 4 hours
Inhalation LC50 (Rat) :
Eye Contact: slightly irritating (Rabbit)
Skin Contact: slightly irritating (Rabbit)
Skin Sensitization: Not a sensitizer (Guinea Pig)
Mutagenic Potential
Fludioxonil: Genotoxic in one study; negative in five others
Reproductive Hazard Potential
Fludioxonil: Delayed development at doses causing maternal toxicity
Chronic/Subchronic Toxicity Studies
Liver and kidneys toxicity high dose levels
Fludioxonil:
Carcinogenic Potential
Fludioxonil: Marginal increase (7%) of liver tumors (female, rats: 3,000 ppm); Within historical control range
Product Name: Page: 3
MEDALLION
(1 to 10%).
Other Toxicity Informatio
Not Available
Toxicity of Other Components
Dispersing Agent
Dust may produce a respiratory allergenic response and/or irritation in some individuals. May cause severe eye
injury but the damage is reversible.
Sodium Sulfate
Exposure may cause irritation of the nose, throat and lungs. Repeated or prolonged contact to the skin results in
dermatitis. May cause mild irritation to the eyes.
Solid Diluent
May cause irritation to upper erspiratory tract. Long term excessive exposures may cause a pulmonary fibrosis
and may lead to severe and permanent damage to lungs. Abrasion may cause eye and skin irritation.
Surfactant
Exposure can result in eye, skin and respiratory tract irritation.
Wetting Agent
Exposure to skin and eyes may result in irritation.
Target Organs
Active Ingredients
Fludioxonil : Liver and Kidneys
Inert Ingredients
Dispersing Agent Not Available
:
Sodium Sulfate Respiratory Tract, Skin and Eyes
:
Solid Diluent Lungs
:
Surfactant Eyes, Skin and Respiratory Tract
:
Wetting Agent None Known
:
12. ECOLOGICAL INFORMATION
Summary of Effects
Fludioxonil:
Practically nontoxic to birds, but highly toxic to aquatic invertebrates and fish.
Eco-Acute Toxicity
Fludioxonil: Rainbow Trout 96-hour LC50 0.47 mg/l
Bluegill Sunfish 96-hour LC50 0.74 mg/l
Daphnia magna 48-hour LC50 0.90 mg/l
Bobwhite Oral LD50 >2,000 mg/kg
Mallard Oral LD50 >2,000 mg/kg
Bobwhite 8-day Dietary LC50 >5,200 ppm
Mallard 8-day Dietary LC50 >5,200 ppm
Eco-Chronic Toxicity
Fludioxonil: Fish (Fathead minnow) Early Life Stage MATC 0.028 mg/l
Invertebrate (Daphnia Magna) Life Cycle MATC 0.025 mg/l
Mallard Reproduction NOEC 700 ppm
Bobwhite Reproduction NOEC 125 ppm
Environmental Fate
Fludioxonil:
Not Available
Product Name: Page: 4
MEDALLION
13. DISPOSAL CONSIDERATION
Disposal
Do not reuse product containers. Dispose of product containers, waste containers, and residues according to local, state,
and federal health and environmental regulations.
Characteristic Waste Not Applicable
Listed Waste: Not Applicable
14. TRANSPORT INFORMATION
DOT Classification:
Not Applicable; No Label or Placard Required
B/L Freight Classification
Insecticides or Fungicides; Agricultural, N.O.S.
International Transportation
Not Applicable
15. REGULATORY INFORMATION
SARA Title III Classification
Section 311/312: Acute Health Hazard
Chronic Health Hazard
Section 313 chemical(s): Not Applicabl
Proposition 65
Not Applicable
CERCLA Reportable Quantity (RQ)
None
RCRA Classification
Not Applicable
TSCA Status
Exempt from TSCA
16. OTHER INFORMATION
NFPA Hazard Ratings 0 Least
1
Health: 1 Slight
2 Moderate
0
Flammability:
3 High
0
Reactivity:
4 Severe
Questions concerning the safe handling of the product should be referred to:
Industrial Health
1-800-334-9481
Issued Date: 6/28/94
Revised Date: 1/21/98
8/5/98 Supersedes:
The information and recommendations contained herein are based upon data believed to be correct.
However, no guarantee or warranty of any kind, expressed or implied, is made with respect to the
information contained herein.
RSVP# : NCP-955-769A-00118D
Product Name: Page: 5
MEDALLION
|