MATERIAL SAFETY DATA SHEET
COMMAND庐 4 EC HERBICIDE
MSDS Ref. No: 81777-89-1-1
Version: Global
Date Approved: 01/11/2002
Revision No: 8
This document has been prepared to meet the requirements of the U.S. OSHA Hazard
Communication Standard, 29 CFR 1910.1200; the EC directive, 91/155/EEC and other regulatory
requirements. The information contained herein is for the concentrate as packaged, unless otherwise
noted.
1. PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME: COMMAND庐 4 EC HERBICIDE
PRODUCT CODE: 1584
ACTIVE INGREDIENT: Clomazone
CHEMICAL FAMILY: Herbicide
MOLECULAR FORMULA: C12H14ClNO2 (clomazone)
SYNONYMS: FMC 57020; 2-(2-chlorophenyl)methyl-4,4-dimethyl-3-isoxazolidinone; IUPAC: 2-
(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one; 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-
3-one
ALTERNATE TRADENAME(S): Merit
MANUFACTURER Emergency Telephone Numbers:
FMC CORPORATION Emergency Phone (FMC) 800-331-3148
Agricultural Products Group (U.S.A. & Canada)
1735 Market Street Emergency Phone (FMC) 716-735-3765
Philadelphia, PA 19103 USA (Reverse charges)
CHEMTREC (U.S.): (800) 424-9300
(U.S.A. & Canada)
(202) 483-7616 (All other countries)
2. COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Name CAS# Wt.% PEL/TLV EC No. EC Class
Clomazone 81777-89-1 46.7 None None None
Aromatic Hydrocarbons 64742-95-6 <25 100 ppm 650-001-00-0 R65
(supplier)
1,2,4-trimethylbenzene 95-63-6 <13.5 25 ppm None None
Surfactant Blend 0000-00-0 <7 None None None
Xylene 1330-20-7 <1.3 100 ppm 601-022-00-9 R11-20/21-38
150 ppm
STEL
1-butanol 71-36-3 <0.6 50 ppm 603-004-00-6 R10-20
(skin)
(ceiling)
Cumene 98-82-8 <0.6 50 ppm 601-024-00-X R10-37
(skin) 50
ppm
Ethylbenzene 100-41-4 <0.2 100 ppm 601-023-00-4 R11/20
100 ppm
125 ppm
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
IMMEDIATE CONCERNS: - Straw yellow liquid with an aromatic solvent odor.
- Moderately combustible. May support combustion if heated above the product's
flash point (see Section 5, "Fire Fighting Measures" below).
- Thermal decomposition and burning may form toxic by-products.
- For large exposures or fire, wear personal protective equipment.
- Slightly to moderately toxic to fish and aquatic organisms. Keep out of drains and water
courses.
- Moderately irritating to the eyes.
POTENTIAL HEALTH EFFECTS: Effects from overexposure result from either
swallowing, inhaling or coming into contact with the eyes or skin. Symptoms of overexposure
include decreased activity, tearing eyes, bleeding from the nose and incoordination.
MEDICAL CONDITIONS AGGRAVATED: None presently known.
4. FIRST AID MEASURES
EYES: Flush with water for at least 15 minutes. If irritation occurs and persists, contact a
medical doctor.
SKIN: Wash with plenty of soap and water. Get medical attention if irritation occurs and
persists.
INGESTION: Rinse mouth with water. Dilute by giving 1 or 2 glasses of water. Do not
induce vomiting. Never give anything by mouth to an unconscious person. See a medical
doctor immediately.
INHALATION: Remove to fresh air. If breathing difficulty or discomfort occurs and
persists, contact a medical doctor.
NOTES TO MEDICAL DOCTOR: This product has low oral, dermal and inhalation
toxicity. It is moderately irritating to the eyes and slightly irritating to the skin. Direct contact
with eyes may produce corneal damage, especially if not washed out immediately. Inert
ingredients contain xylene-range aromatic solvents which may produce a chemical
pneumonitis; therefore, vomiting is not recommended, and lavage requires intubation.
Activated charcoal and cathartics will assist gastrointestinal tract evacuation.
5. FIRE FIGHTING MEASURES
FLASH POINT AND METHOD: 40掳C (104掳F) (TCC)
EXTINGUISHING MEDIA: Foam, CO2 or dry chemical. Soft stream water fog only if
necessary. Contain all runoff.
FIRE / EXPLOSION HAZARDS: Moderately combustible. When heated above the
flash point, this material releases vapors which, when mixed with air, can burn or be
explosive.
FIRE FIGHTING PROCEDURES: Isolate fire area. Evacuate downwind. Wear full
protective clothing and self-contained breathing apparatus. Do not breathe smoke, gases or
vapors generated.
HAZARDOUS DECOMPOSITION PRODUCTS: Carbon monoxide and/or carbon
dioxide, oxides of nitrogen, chlorine and hydrogen chloride.
6. ACCIDENTAL RELEASE MEASURES
RELEASE NOTES: Isolate and post spill area. Wear protective clothing and personal
protective equipment as prescribed in Section 8, "Exposure Controls/Personal Protection".
Keep unprotected persons and animals out of the area.
Keep material out of lakes, streams, ponds and sewer drains. Dike to confine spill
and absorb with a non-combustible absorbent such as clay, sand or soil. Vacuum,
shovel or pump waste into a drum and label contents for disposal.
To clean and neutralize tools and equipment, wash with a 20% solution of potassium
hydroxide in methanol. Follow by washing with strong soap and rinsing with water,
and add both solutions to the drums of waste already collected.
To clean and neutralize spill areas, spray the area with a 20% solution of potassium
hydroxide in methanol. Cover the treated area with plastic and let stand for 24 hours.
Remove the covering and place in a drum for later disposal. Wash the area, three
times, with a strong soap and rinse with water. If spill occurs on a wooden surface,
repeat the entire process again. Absorb, as above, any excess liquid and add to the
drums of waste already collected. Dispose of drummed waste according to the
method outlined in Section 13, "Disposal Considerations".
7. HANDLING AND STORAGE
GENERAL PROCEDURES: Store in a cool, dry, well-ventilated place. Do not use or
store near heat, open flame or hot surfaces. Store in original containers only. Keep out of
reach of children and animals. Do not contaminate other pesticides, fertilizers, water, food or
feed by storage or disposal.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
ENGINEERING CONTROLS: Use local exhaust at all process locations where vapor or mist
may be emitted. Ventilate all transport vehicles prior to unloading.
PERSONAL PROTECTIVE EQUIPMENT
EYES AND FACE: For splash, mist or spray exposure, wear chemical protective goggles
or a face shield.
RESPIRATORY: For splash, mist or spray exposure wear, as a minimum, a properly
fitted half-face or full-face air-purifying respirator which is approved for pesticides (U.S.
NIOSH/MSHA, EU CEN or comparable certification organization). Respirator use and
selection must be based on airborne concentrations.
PROTECTIVE CLOTHING: Depending upon concentrations encountered, wear
coveralls or long-sleeved uniform and head covering. For larger exposures as in the case of
spills, wear full body cover barrier suit, such as a PVC suit. Leather items - such as shoes,
belts and watchbands - that become contaminated should be removed and destroyed. Launder
all work clothing before reuse (separately from household laundry).
WORK HYGIENIC PRACTICES: Clean water should be available for washing in
case of eye or skin contamination. Wash skin prior to eating, drinking or using tobacco.
Shower at the end of the workday.
GLOVES:
Wear chemical protective gloves made of materials such as neoprene. Thoroughly wash the
outside of gloves with soap and water prior to removal. Inspect regularly for leaks.
9. PHYSICAL AND CHEMICAL PROPERTIES
ODOR: Aromatic solvent
APPEARANCE: Straw yellow liquid
SOLUBILITY IN WATER: Emulsifies
SPECIFIC GRAVITY: 1.021 - 1.024 (water = 1)
MOLECULAR WEIGHT: 239.7 (clomazone)
WEIGHT PER VOLUME: 8.57 lb/gal. (1021 - 1024 g/L)
10. STABILITY AND REACTIVITY
CONDITIONS TO AVOID: Excessive heat and fire.
STABILITY: Stable
POLYMERIZATION: Will not occur
11. TOXICOLOGICAL INFORMATION
DERMAL LD50: >2000 mg/kg (rabbit)
ORAL LD50: 1406 mg/kg (rat)
INHALATION LC50: 4.47 mg/L/4 hr (rat)
ACUTE EFFECTS FROM OVEREXPOSURE: This product has low oral, dermal
and inhalation toxicity. It is moderately irritating to the eyes and slightly irritating to the skin.
Large dosages of clomazone ingested by laboratory animals produced signs of toxicity
including ataxia, decreased activity, oral discharge, lacrimation, bloody tears, and nasal
discharge. Inhalation of aromatic hydrocarbon vapors may cause dizziness, disturbances in
vision, drowsiness, respiratory irritation, and eye, skin and mucous membrane irritation.
Vomiting after ingestion of this product may cause aspiration of aromatic hydrocarbons into
the lungs which may result in fatal pulmonary edema. Exposure to butanol vapors may
produce headaches, drowsiness and irritation of the nose and throat. Excessive exposures to
butanol liquid or vapors may result in contact dermatitis and irritation of the mucous
membranes.
CHRONIC EFFECTS FROM OVEREXPOSURE: No data available for the
formulation. In studies with laboratory animals, clomazone did not cause reproductive
toxicity, teratogenicity, or carcinogenicity. Liver enlargement and elevated cholesterol levels
are often noted in laboratory animals that have ingested large doses of clomazone during
their lifespan. An overall absence of genotoxicity has been demonstrated in tests of
mutagenicity, DNA damage and chromosome aberrations. Chronic exposure to aromatic
hydrocarbons may cause headaches, dizziness, loss of sensations or feelings (such as
numbness), and liver and kidney damage. Inhalation of xylene vapors at high doses has also
resulted in an increased incidence of malformations and decreases in fetal weight in
laboratory animals. Damage from xylene may be potentiated by alcohol. Disturbances in
hearing and balance have been reported in workers exposed to butanol vapors. Under the
conditions of 2-year inhalation studies, conducted by the National Toxicology Program
(NTP), there was clear evidence of carcinogenic activity of ethylbenzene in male rats based
on increased incidences of renal tubule neoplasms. The incidences of testicular adenoma
were also increased. There was some evidence of carcinogenic activity in female rats based
on increased incidences of renal tubule adenomas. There was some evidence of carcinogenic
activity in male mice based on increased incidences of alveolar/bronchiolar neoplasm. There
was some evidence of carcinogenic activity in female mice based on increased incidences of
hepatocellular neoplasms. Studies conducted by the International Agency for Research on
Cancer (IARC) showed that there is inadequate evidence in humans for the carcinogenicity
of ethylbenzene and that there is sufficient evidence in experimental animals; therefore, the
overall evaluation shows that ethylbenzene is possibly carcinogenic to humans (Group 2B).
NTP IARC OSHA
Chemical Name Other
Status Status Status
Not listed
Ethylbenzene Listed Listed Not listed
(ACGIH)
12. ECOLOGICAL INFORMATION
Unless otherwise indicated, the data presented below are for the active ingredient.
ENVIRONMENTAL DATA: Clomazone has a moderate rate of degradation in soil
(half-life = 24 days), and is stable to hydrolysis over a wide range of pH. The
bioconcentration potential for clomazone is low, with a Log Pow of 2.5, and a measured
bioconcentration factor (BCF) of 27 - 40. Field studies showed that clomazone does not
significantly leach below 15 cm in soil and is, therefore, not expected to enter groundwater.
ECOTOXICOLOGICAL INFORMATION: Clomazone technical:
Freshwater fish: 96-hour LC50 = 19 (Rainbow trout) (slightly toxic)
Freshwater fish: 96-hour LC50 = 34 (Bluegill sunfish) (slightly toxic)
Estuarine invertebrates: 96-hour LC50 = 8.9 mg/L (Pink shrimp) (moderately toxic)
Estuarine fish: LC50 = 6.3 (Atlantic silverside, moderately toxic) - 41 mg/L (Sheepshead
minnow, slightly toxic)
Estuarine invertebrate: LC50 = 0.57 mg/L (Mysid) (highly toxic)
Waterfowl / Upland game birds: Oral LD50 >2510 mg/kg; Dietary LC50 >5620 ppm (low
toxicity)
Care should be taken to avoid contamination of the aquatic environment.
13. DISPOSAL CONSIDERATIONS
DISPOSAL METHOD: Open dumping or burning of this material or its packaging is
prohibited. If spilled material cannot be disposed of by use according to label instructions, an
acceptable method of disposal is to incinerate in accordance with local, state and national
environmental laws, rules, standards and regulations. However, because acceptable methods
of disposal may vary by location and regulatory requirements may change, the appropriate
agencies should be contacted prior to disposal.
EMPTY CONTAINER: Non-returnable containers which held this material should be
cleaned, prior to disposal, by triple rinsing. Containers which held this material may be
cleaned by being triple-rinsed, and recycled, with the rinsate being incinerated. Do not cut or
weld metal containers. Vapors that form may create an explosion hazard.
14. TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION (DOT)
REPORTABLE QUANTITY (RQ): None
U.S. SURFACE FREIGHT CLASS: Compound, weed killing (herbicide), NOI.
NMFC Item 50320.
MARINE POLLUTANT #1: Not listed
OTHER SHIPPING INFORMATION:
For highway and railroad shipment in the U.S.A. :
Compound, weed killing (herbicides), NOI. NMFC Item 50320
For air and water shipment, and also road and rail other than in the U.S.A. :
Flammable liquids, n.o.s. (contains xylene), 3, UN1993, III. NAERG
Guide 128.
15. REGULATORY INFORMATION
UNITED STATES
SARA TITLE III (SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT)
SECTION 302 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355):
Not listed
SECTION 311 HAZARD CATEGORIES (40 CFR 370): Immediate, Delayed,
Fire
SECTION 312 THRESHOLD PLANNING QUANTITY (40 CFR 370): The
threshold planning quantity (TPQ) for this product, if treated as a mixture, is 10,000 lbs. This
product contains the following ingredients with a TPQ of less than 10,000 lbs.: None
SECTION 313 REPORTABLE INGREDIENTS (40 CFR 372): This product
contains the following ingredients subject to Section 313 reporting requirements: (1,2,4-
trimethylbenzene) (xylene, mixed isomers) (ethylbenzene) (1-butanol)
CERCLA (COMPREHENSIVE ENVIRONMENTAL RESPONSE
COMPENSATION AND LIABILITY ACT): Listed.
Chemical Name Wt.% RQ
Xylene <1.3 100 lbs.
1-butanol <0.6 5000 lbs.
Cumene <0.6 5000 lbs.
Ethylbenzene <0.2 1000 lbs.
COMMENTS: Australian Hazard Code : 3XE
U.S. EPA Signal Word : WARNING
16. OTHER INFORMATION
REVISION SUMMARY
This MSDS replaces Revision #7, dated December 11, 2001. Changes in information are as
follows:
Section 11 (Toxicological Information)
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