The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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"DuPont" "LANNATE" SP INSECTICIDE
M0000388 Revised 16-MAY-2003
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"LANNATE" is a registered trademark of DuPont.
"DuPont" is a trademark of DuPont.
Corporate MSDS Number : DU008251
Grade : A 90% FORMULATION
Tradenames and Synonyms
"Lannate" 90-WD
90-WD
Yugo
"LANNATE" SP
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
METHOMYL 16752-77-5 90
(S-METHYL-N-[(METHYLCARBAMOYL)OXY]THIO-
ACETIMIDATE)
INERT INGREDIENTS 10
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Material Safety Data Sheet
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HAZARDS IDENTIFICATION
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Emergency Overview
DANGER!
Fatal if swallowed. May be fatal if inhaled or absorbed
through the eyes. Harmful if absorbed through the skin.
Do not get in eyes, on skin, or on clothing. Do not breathe
vapors or spray mist. Pilot should not assist in the mixing
and loading operation.
Potential Health Effects
WARNING SYMPTOMS
Methomyl poisoning produces effects associated with
anticholinesterase activity which may include weakness,
blurred vision, headache, nausea, abdominal cramps,
discomfort in the chest, constriction of pupils, sweating,
slow pulse, muscle tremors.
Human health effects from single ingestion of Methomyl at doses of
0.1, 0.2, or 0.3 mg/kg caused temporary cholinesterase and
hematologic effects. No other adverse effects were observed. The
NOAEL was 0.1 mg/kg.
Skin, eye, inhalation or ingestion exposure to Methomyl may cause
acute cholinesterase depression characterized by nonspecific
discomfort, such as nausea, headache, weakness, cramps, excessive
sweating, salivation and tearing, constricted pupils, blurred
vision; muscle twitching, and confusion. Higher exposures may
lead to loss of consciousness; or convulsions and severe
respiratory depression.
Skin contact with Methomyl may cause skin irritation with
discomfort or rash. Evidence suggests that skin permeation can
occur in amounts capable of producing the effects of systemic
toxicity.
Eye contact with Methomyl may cause eye irritation with
discomfort, tearing, or blurring of vision.
Individuals with preexisting diseases of the central nervous
system or conditions which lower cholinesterase levels may have
increased susceptibility to the toxicity of excessive exposures.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
M0000388 DuPont Page 3
Material Safety Data Sheet
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FIRST AID MEASURES
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First Aid
THIS PRODUCT IS AN N-METHYL CARBAMATE INSECTICIDE.
INGESTION:
IF SWALLOWED: Call a poison control center or doctor
immediately for treatment advice. Drink 1 or 2 glasses of
water and induce vomiting by touching back of throat with
finger. Do not induce vomiting or give anything by mouth to
an unconscious person.
EYE CONTACT:
IF IN EYES: Hold eye open and rinse slowly and gently with
water for 15-20 minutes. Remove contact lenses, if present,
after the first 5 minutes, then, continue rinsing eye. Call
a poison control center or doctor for treatment advice.
INHALATION:
IF INHALED: Move person to fresh air. If person is not
breathing, call 911 or an ambulance, then give artificial
respiration, preferably by mouth-to-mouth, if possible.
Call a poison control center or doctor for treatment advice.
SKIN CONTACT:
IF ON SKIN OR CLOTHING: Take off contaminated clothing.
Rinse skin immediately with plenty of water for 15-20
minutes. Call a poison control center or doctor for
treatment advice.
ATROPINE IS AN ANTIDOTE - SEEK MEDICAL ATTENTION AT ONCE IN
ALL CASES OF SUSPECTED POISONINGS.
If warning symptoms appear (see WARNING SYMPTOMS), get
medical attention.
Have the product container or label with you when calling
a poison control center or doctor, or going for treatment.
You may also call 1-800-441-3637 for emergency medical
treatment information.
Notes to Physicians
WARNING SYMPTOMS - Methomyl poisoning produces effects
associated with anticholinesterase activity, which may
include weakness, blurred vision, headache, nausea,
abdominal cramps, discomfort in the chest, constriction of
pupils, sweating, slow pulse, and muscle tremors.
TREATMENT - Atropine sulfate should be used for treatment.
Administer repeated doses, 1.2 to 2.0 mg intravenously every
10 to 30 minutes until full atropinization is achieved.
Maintain atropinization until the patient recovers.
Artificial respiration or oxygen may be necessary. Allow no
M0000388 DuPont Page 4
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
further exposure to any cholinersterase inhibitor until
recovery is assured.
Do not use 2-PAM for exposure to "Lannate" SP alone.
However, for exposure to combinations of "Lannate" SP and
organophosphorous insecticides, 2-PAM may be used as
required to supplement the atropine sulfate treatment as
described above. Do not use morphine.
For medical emergencies involving this product, call toll
free 1-800-441-3637.
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FIRE FIGHTING MEASURES
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# Flammable Properties
Flammable limits in Air, % by Volume
LEL : 0.096 g/L
Autodecomposition : 136 C (277 F)
Will ignite if exposed to intense heat or open flame.
Dust forms explosive mixture with air.
Fire and Explosion Hazards:
Fire or intense heat may cause violent rupture of packages.
Heating can release vapors which can be ignited. Hazardous
gases produced in fire under conditions that produce
incomplete combustion may consist of SO2, NO2, CO2, HCN,
CH3NCO, CO, CS2. Complete combustion greatly reduces the
amounts of CS2, CO, HCN, and CH3NCO generated.
Extinguishing Media
Water Spray, Water Fog, Dry Chemical, CO2.
Fire Fighting Instructions
Evacuate personnel to a safe area. Keep personnel removed and
upwind of fire. Wear self-contained breathing apparatus. Wear
full protective equipment. Use water spray. Cool tank/container
with water spray. Isolate area. Fight fire from maximum
distance, use extreme caution as heat may decompose material and
rupture containers.
If area is exposed to fire and conditions permit, let fire burn
itself out. Burning chemicals may produce by-products more toxic
than the original material. If product is on fire, wear
self-contained breathing apparatus and full protective equipment.
Use water spray. Control runoff.
M0000388 DuPont Page 5
Material Safety Data Sheet
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Emergency Response - Chemical resistant coveralls,
waterproof gloves, waterproof boots and face/eye protection.
If dusting occurs, use NIOSH approved respirator protection.
Initial Containment
Remove source of heat, sparks, flame, impact, friction or
electricity.
Follow applicable Federal, State/Provincial and Local laws/
regulations.
Prevent material from entering sewers, waterways, or low areas.
Accidental Release Measures
Contain spill. Shovel or sweep up powder. Use sawdust,
sand, oil dry or other absorbent material as an aid to
removing remaining traces of spilled material. Do not allow
the material to enter sewers, waterways or low areas.
If product enters crevices and can not be removed, treat
with a sodium hydroxide solution and allow to stand 4 hours.
NOTE: Sodium hydroxide is caustic and causes burns. Do not
get in eyes, on skin, or on clothing. In case of contact,
flush eyes or skin with plenty of water and call a
physician. When handling, wear goggles in addition to boots
and gloves.
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HANDLING AND STORAGE
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Handling (Personnel)
Do not breathe vapor or mist. Do not get in eyes, on skin, or on
clothing.
USERS SHOULD: Wash hands before eating, drinking, chewing gum,
using tobacco or using the toilet.
Remove clothing immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
Remove personal protective equipment immediately after handling
this product. Wash the outside of gloves before removing. As
soon as possible, wash thoroughly and change into clean clothing.
M0000388 DuPont Page 6
Material Safety Data Sheet
(HANDLING AND STORAGE - Continued)
Handling (Physical Aspects)
Avoid dust generation. Keep away from heat, sparks and flames.
Do not open, rip, tear, cut or perforate the inner water
soluble bag.
Storage
Handle this package carefully to prevent breakage of inner
bag when stored at low temperatures. Allow to warm above 50
deg F for normal handling. Store product in original
container only. Do not contaminate water, other pesticides,
fertilizer, food or feed in storage. Not for use or storage
in or around the home.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Use only with adequate ventilation. Keep container tightly closed.
Human flaggers must be in enclosed cabs. Pilot should not
assist in the mixing and loading operation.
Personal Protective Equipment
Applicators and other handlers must wear:
Long-sleeved shirt and long pants.
Chemical Resistant Gloves Category A (such as butyl
rubber, natural rubber, neoprene rubber, or nitrile
rubber) are equal to or greater than 14 mils.
Shoes plus socks.
Protective eye wear.
For exposures in enclosed areas, a respirator with either an
organic vapor-removing cartridge with a prefilter approved
for pesticides (MSHA/NIOSH approval number prefix TC-23C),
or a canister approved for pesticides (MSHA/NIOSH approval
number prefix TC-14G), or NIOSH approved respirator with an
organic vapor (OV) cartridge or a canister with any R, P, or
HE prefilter.
For exposures outdoors, Dust/mist filtering respirator
(MSHA/NIOSH approval number prefix TC-21C), or a NIOSH
approved respirator with any R, P, or HE prefilter.
Cleaners and repairers of application equipment must wear:
Long-sleeved shirt and long pants.
Chemical resistant gloves.
Chemical resistant footwear.
M0000388 DuPont Page 7
Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
Protective eyewear.
Respirator as outlined above.
Chemical resistant apron.
Discard clothing or other absorbent materials that have been
drenched or heavily contaminated with this product鈥檚
concentrate. Do not reuse them. Follow manufacturer鈥檚
instructions for cleaning/maintaining PPE. If no such
instructions for washables, use detergent and hot water.
Keep and wash PPE separately from other laundry.
PPE required for early entry to treated areas that is
permitted under the Worker Protection Standard and that
involves contact with anything that has been treated, such
as plants, soil or water is:
Coveralls.
Chemical Resistant Gloves Category A (such as butyl
rubber, natural rubber, neoprene rubber or nitrile
rubber), all equal to or greater than 14 mils.
Shoes plus socks.
Protective eyewear.
Exposure Guidelines
Applicable Exposure Limits
METHOMYL
PEL (OSHA) : None Established
TLV (ACGIH) : 2.5 mg/m3, 8 Hr. TWA, A4
AEL * (DuPont) : None Established
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Solubility in Water : 5.8 WT% @ 25 C (77 F)
Odor : Slightly sulfurous
Form : Solid
Color : White
Specific Gravity : 1.2946 @ 25C (77F)
Bulk Density (Loose) : 30-38 lb/cu ft
Bulk Density (Packed) : 37-43 lb/cu ft
Bulk Density (Loose): 480.6-608.7 kg/m3
Bulk Density (Packed): 592.7-688.8 kg/m3
M0000388 DuPont Page 8
Material Safety Data Sheet
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Incompatible with strong bases.
Polymerization
Polymerization will not occur.
Other Hazards
Decomposition : Thermal decomposition and combustion will
produce hazardous gases. These may
include sulfur oxides, methyl isocyanate
and hydrogen cyanide.
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TOXICOLOGICAL INFORMATION
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Animal Data
Methomyl
Inhalation 4 hour LC50: 0.258 mg/L in rats
(Moderately toxic by inhalation)
Skin absorption LD50: > 2,000 mg/kg in rabbits
(Slightly to moderately toxic by contact)
Oral LD50: 34 mg/kg in male rats
Oral LD50: 30 mg/kg in female rats
(Highly toxic by ingestion)
Methomyl is not a skin irritant or a skin sensitizer, but is a
mild eye irritant in animals.
METHOMYL
Ocular exposure with Methomyl caused pupillary constriction,
incoordination, tremors, convulsions, profuse salivation,
lethargy, rales, and/or fasciculations were also observed in
rabbits approximately 1 and 20 minutes after treatment with
10 mg of methomyl. Pupillary constriction was still evident
after 1 hour. These clinical signs are typical of
anticholinesterase activity. These effects were not present
the day after treatment.
Effects of a single inhalation exposure to Methomyl include
weight loss, respiratory irritation, diarrhea, lethargy, as
well as temporary decreased plasma cholinesterase activity,
abnormal gait, hyperactivity and tremors. Corneal opacity
was noted in one rat exposed to near-lethal concentrations.
Repeated exposures at 15 mg/m3 produced no histopathological
M0000388 DuPont Page 9
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
changes in lung, spleen, kidney, liver, brain, eyes or oral
and nasal mucosa.
Effects of a single dermal exposure to Methomyl include
rapid respiration, miosis and nervous system effects such as
tremors. Repeated exposure produced respiratory irritation
and labored breathing, and nervous system effects such as
miosis and depression.
A single ingestion exposure to Methomyl produced nervous
system effects as described for inhalation and skin
exposures. Repeated exposure at approximately 5 mg/kg
produced signs of nervous system effects (mild tremors)
without clinical or pathological signs of toxicity. Feeding
studies in rats and mice produced only mild effects having
no clear toxicological significance. Long-term feeding
studies at dietary levels up to 1,000 ppm produced lowered
red blood counts and hematocrit, indications of nervous
system effects and histopathological changes in kidneys,
spleen, liver and bone marrow.
In a 91-day oral Neurotoxicity study in rats, most of the
effects observed appeared to be acute in nature. There were
no morphological changes in the nervous system. The NOEL in
this study was 150 ppm, based on clinical and biochemical
evidence of cholinesterase activity inhibition.
Test in animals demonstrate no carcinogenic, developmental,
or reproductive toxicity. (One test in mice reports
abnormal sperm morphology).
Methomyl does not produce genetic damage in animals, or in
bacterial and mammalian cell cultures.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
AQUATIC TOXICITY:
METHOMYL
96 hour LC50 - Bluegill sunfish: 0.72 mg/L.
MATC, fathead minnows : 104 ug/L
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Material Safety Data Sheet
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations. Do not contaminate water supply, food or feed by
storage or disposal.
Pesticide wastes are acutely hazardous. Improper disposal of
excess pesticide, spray mixture, or rinsate is a violation
of Federal law. If these wastes cannot be disposed of by
user according to label instructions, contact your State
Pesticide or Environmental Control Agency, or the Hazardous
Waste representative at the nearest EPA regional office for
guidance.
Environmental Hazards
This pesticide is toxic to fish and wildlife. Drift and
runoff from treated areas may be hazardous to aquatic
organisms in neighboring areas.
Do not apply directly to water, or to areas where surface
water is present, or to intertidal areas below the mean high
water mark. Do not contaminate water when disposing of
equipment washwaters.
This product is highly toxic to bees exposed to direct
treatment on blooming crops or weeds. Do not apply this
product or allow it to drift to blooming crops or weeds
while bees are actively visiting the treatment area.
Container Disposal
For Fiber Drums with Liners: Completely empty liner by
shaking and tapping sides and bottom to loosen clinging
particles. Empty residue into manufacturing equipment.
Then dispose of liner in a sanitary landfill or by
incineration if allowed by state and local authorities. If
drum is contaminated and cannot be reused, dispose of in the
same manner.
For Water Soluble Packets: Do not reuse the outer box or
the resealable plastic bag. When all water-soluble packets
are used, the outer packaging should be clean and may be
disposed of in a sanitary landfill or by incineration, or if
allowed by state and local authorities, by open burning. If
burned, stay out of smoke. If the resealable plastic bag
contacts the formulated product in any way, the bag must be
triple-rinsed with clean water. Add the rinsate to the
spray tank and dispose of the outer wrap as described above.
For Paper and Plastic Bags: Completely empty bag into
application equipment. Then dispose of empty bag in a
M0000388 DuPont Page 11
Material Safety Data Sheet
(DISPOSAL CONSIDERATIONS - Continued)
sanitary landfill or by incineration, or if allowed by state
and local authorities, by burning. If burned, stay out of
smoke.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO
Proper Shipping Name : CARBAMATE PESTICIDE, SOLID, TOXIC
(methomyl)
Hazard Class : 6.1
UN No. : UN 2757
Special Information : Marine Pollutant (water or bulk)
Packing Group : II
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REGULATORY INFORMATION
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U.S. Federal Regulations
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No
In the United States this product is regulated by the US
Environmental Protection Agency under the Federal Insecticide,
Fungicide and Rodenticide Act. It is a violation of federal law
to use this product in a manner inconsistent with its labeling.
EPA Reg. No. 352-342
ADDITIONAL REGULATORY INFORMATION
Section 302 Extremely Hazardous Substance:
Methomyl - Threshold Planning Quantity (TPQ)
(500/10,000 lb)
SARA/CERCLA Reportable Quantity:
Methomyl (100 lb)
M0000388 DuPont Page 12
Material Safety Data Sheet
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health :2
Flammability :1
Reactivity :1
NPCA-HMIS Rating
Health :3
Flammability :1
Reactivity :1
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information
RESTRICTED USE PESTICIDE
Due to High Acute Toxicity to Humans
For retail sale and use only by Certified Applicators or
persons under their direct supervision and only for those
uses covered by the Certified Applicator鈥檚 certification.
Direct supervision for this product requires the certified
applicator to review federal and supplemental label
instructions with all personnel prior to application,
mixing, loading, or repair or cleaning of application
equipment.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS: DuPont Crop Protection
Address : Wilmington, DE 19898
Telephone : 1-888-638-7668
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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