The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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"DuPont" "VELPAR" DF HERBICIDE
M0000325 Revised 25-JUN-2003
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
VELPAR is a registered trademark of DuPont.
"DuPont" is a trademark of DuPont.
Corporate MSDS Number : DU008210
# Tradenames and Synonyms
"Velpar" F
"VELPAR" 75WG
DUPONT VELPAR 75WG
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
*HEXAZINONE 51235-04-2 75
(3-cyclohexyl-6-(dimethylamino)-1-methyl-1,3,5-
triazine-2,4(1H,3H)-dione)
INERT INGREDIENTS 25
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
M0000325 DuPont Page 2
Material Safety Data Sheet
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HAZARDS IDENTIFICATION
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Emergency Overview
DANGER Corrosive, causes irreversible eye damage.
Harmful if swallowed. Do not get in eyes or on
clothing. Avoid contact with skin. Wash thoroughly with soap
and water after handling.
Potential Health Effects
HUMAN HEALTH EFFECTS OF OVEREXPOSURE TO HEXAZINONE:
Overexposure to hexazinone by eye contact may initially
include eye irritation with discomfort, tearing, or blurring
of vision.
Ingestion may include abnormal liver function as detected by
laboratory tests.
Significant skin permeation and systemic toxicity after
contact appears unlikely. Individuals with preexisting
diseases of the liver may have increased susceptability to
the toxicity of excessive exposures.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
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FIRST AID MEASURES
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First Aid
IF IN EYES: Hold eye open and rinse slowly and gently with
water for 15-20 minutes. Remove contact lenses, if present,
after the first 5 minutes, then continue rinsing eye. Call
a poison control center or doctor for treatment advice.
IF ON SKIN OR CLOTHING: Take off contaminated clothing.
Rinse skin immediately with plenty of water for 15-20
minutes. Call a poison control center or doctor for
treatment advice.
IF SWALLOWED: Call a poison control center or doctor
immediately for treatment advice. Have person sip a glass
of water if able to swallow. Do not induce vomiting unless
told to do so by the poison control center or doctor. Do
not give anything by mouth to an unconscious person.
INHALATION: No specific intervention is indicated, as the
compound is not likely to be hazardous by inhalation.
Consult a physician if necessary.
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Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Notes to Physicians
Probable mucosal damage may contraindicate the use of
gastric lavage.
Have the product container or label with you when calling a
poison control center or doctor, or going for treatment. You
may also contact 1-800-441-3637 for emergency medical
treatment information.
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FIRE FIGHTING MEASURES
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Flammable Properties
Not a fire or explosion hazard.
Extinguishing Media
Use media appropriate for surrounding material.
Fire Fighting Instructions
Keep personnel removed and upwind of fire. Wear self-contained
breathing apparatus. Wear full protective equipment.
If area is exposed to fire and conditions permit, let fire burn
itself out. Burning chemicals may produce by-products more toxic
than the original material. If product is on fire, wear
self-contained breathing apparatus and full protective equipment.
Use water spray. Control runoff.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Emergency Response - Chemical resistant coveralls,
waterproof gloves, waterproof boots and face/eye protection.
If dusting occurs, use NIOSH approved respirator protection.
Initial Containment
Dike spill. Prevent material from entering sewers, waterways, or
low areas.
Spill Clean Up
Shovel or sweep up.
M0000325 DuPont Page 4
Material Safety Data Sheet
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HANDLING AND STORAGE
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Handling (Personnel)
Do not get in eyes. Avoid breathing dust. Avoid contact with
skin. Avoid contact with clothing.
USERS SHOULD: Wash hands before eating, drinking, chewing gum,
using tobacco or using the toilet.
Storage
Store product in original container only. Do not contaminate
water, other pesticides, fertilizer, food or feed in storage.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Use only with adequate ventilation.
Personal Protective Equipment
Applicators and other handlers must wear:
Long-sleeved shirt and long pants.
Shoes plus socks.
Protective eye wear
Discard clothing and other absorbent materials that have
been drenched or heavily contaminated with this product鈥檚
concentrate. Do not reuse them.
Follow manufacturer instructions for cleaning and
maintaining PPE. If no such instructions for washables,
use detergent and hot water. Keep and wash PPE separately
from other laundry.
PPE required for early entry to treated areas that is
permitted under the Worker Protection Standard and that
involves contact with anything that has been treated, such
as plants, soil, or water is:
赂Coveralls.
赂Chemical resistant gloves in Category A (such as
赂butyl rubber, natural rubber, neoprene rubber, or
赂Nitrile rubber) all greater than or equal to 14
赂mils.
赂Shoes plus socks.
赂Protective eyewear.
Exposure Guidelines
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Material Safety Data Sheet
Applicable Exposure Limits
HEXAZINONE
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 10 mg/m3, 8 Hr. TWA
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Odor : Acrid (slight).
Form : Dry Flowable Granules.
Color : Tan (light).
pH : 8.4 (1% wt/wt in water)
Density : 0.58 g/mL
Solubility in Water赂 : Water Dispersible
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Incompatible or can react with strong bases.
Decomposition
Decomposition will not occur.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
Acute Oral LD50赂: calculated to be 1310 mg/kg in rats.
Acute Dermal LD50赂: > 5000 mg/kg in rabbits.
Inhalation 4 hour LC50赂: > 5.2 mg/L in rats.
Eye Irritation: In tests with rabbits, product caused
conjunctival chemosis, conjunctival redness, and corneal
opacity. Positive irritant effects were present in 1 rabbit
M0000325 DuPont Page 6
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
21 days after treatment.
Skin irritation and Sensitization: According to criteria
established by the U.S. EPA this product is considered to be
a moderate skin irritant. According to criteria established
by EEC Directive 93/21 this product can be classified a
non-irritant. Product is not a skin sensitizer in tests on
guinea pigs.
OTHER STUDIES - Hexazinone
Oral (rat): In a 2-year feeding study with the 90% powder,
the no-observable-effect level (NOEL) was 200 ppm a.i.;
nutritional and body weight effects were seen in females at
1000 ppm a.i. and in both sexes at 2500 ppm a.i.
Biochemical effects were noted in both sexes at 2500 ppm
a.i.
Oral (mouse): In a 2-year feeding study with technical
material, the no-observable-effect level (NOEL) was 200 ppm.
Decreased body weight gain was observed in both sexes at
2500 ppm and 10000 ppm. This effect was severe at 10000
ppm, the highest level tested. Non-neoplastic liver effects
were noted in males at 2500 ppm and in both sexes at 10000
ppm. Based on recent pathology review, hyperplastic liver
nodules diagnosed at 10000 ppm when this study was initially
conducted have been reclassified as liver adenomas. This
effect was only significant among female mice in this dose
group. This change reflects the current scientific
concensus regarding the classification of this benign lesion
in the mouse liver.
Oral (dog): In a 1-year feeding study with technical
material, the NOEL was 200 ppm. Reduced food consumption
and body weight gains were significant at the high dose,
6000 ppm. These nutritional effects were associated with
mild but reversible changes in hematological parameters at
the high dose. Increased liver weights and other
non-neoplastic liver effects as indicated by histopathology
and changes in clinical chemical parameters were observed at
1500 and/or 60000 ppm.
Reproduction (rat): In a 3-generation, 3-litter study with
90% powder, no adverse reproduction or lactation effects
were seen at any level; slightly depressed average weanling
weights were noted in the second and third litters at the
high dose, 2500 ppm. A second rat reproduction study
(2-generation, 3-litter study) was conducted at dietary
doses from 200 to 5000 ppm. There were no adverse effects
on fertility. The NOEL was 200 ppm. Decreased food
consumption, parental body weight gain and decreased
offspring weights were observed at the higher doses.
Teratogenicity: Not teratogenic or embrryo-fetal toxic to
M0000325 DuPont Page 7
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
rats by dietary administration at levels as high as 5000
ppm, the highest dose tested. Administration to rats by
oral intubation resulted in a NOEL for maternal and fetal
effects of 100 mg/kg body wt./day. Maternal toxicity
(reduced food consumption and lower body weights) was
observed at 400 and 900 mg/kg. Lower fetal weights and
indications of general delayed development associated with
maternal toxicity were also observed at these doses. When
hexazinone was administered to rabbits via oral intubation,
there were no teratogenic or embryo-fetal toxic effects at
the highest dose tested, 125 mg/kg/day. Only a transient
reduction in maternal food consumption was observed at the
high dose. The maternal and fetal NOELs are considered to
be 125 mg/kg.
Mutagenicity: Not mutagenic in Ames bacterial assay, Chinese
hamster ovary cell point mutation assay, or rat liver DNA
repair assay; positive in the in vitro Chinese hamster ovary
cell cytogenetic assay but negative in the in vivo rat bone
marrow cytogenic assay.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity
For the active ingredient hexazinone:
赂96 Hour LC50, bluegill sunfish: >370 ppm
96 Hour LC50, rainbow trout : >320 ppm
赂96 hour LC50, fathead minnow : 274 ppm
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Do not contaminate water, food, or feed by disposal.
Waste resulting from the use of this product may be
disposed of on the site or at an approved waste disposal
facility.
Environmental Hazards
Do not apply directly to water, or to areas where surface
water is present or to intertidal areas below the mean high
water mark. Do not contaminate water when disposing of
equipment washwaters.
The active ingredient, hexazinone, in this product is known
to leach through soil into ground water under certain
conditions as a result of agricultural use. Use of this
chemical in areas where soils are permeable, particularly
where the water table is shallow, may result in ground-water
M0000325 DuPont Page 8
Material Safety Data Sheet
(DISPOSAL CONSIDERATIONS - Continued)
contamination.
Container Disposal
For Plastic Containers: Triple rinse (or equivalent). Then
offer for recycling or reconditioning, or puncture and
dispose of in a sanitary landfill, or incineration, or, if
allowed by State and local authorities, by burning. If
burned, stay out of smoke.
For Fiber Sacks: Completely empty fiber sack by
shaking and tapping sides and bottom to loosen clinging
particles. Empty residue into manufacturing or application
equipment. Then dispose of sack in a sanitary landfill or by
incineration if allowed by State and local authorities.
For Fiber Drums with Liners: Completely empty liners by
shaking and tapping sides and bottom to loosen clinging
particles. Empty residue into manufacturing or
application equipment. Then dispose of liner in a sanitary
landfill or by incineration if allowed by State and
local authorities. If the drum is contaminated and cannot
be reused, dispose of in the same manner.
For Paper and Plastic Bags: Completely empty bag into
application equipment. Then dispose of empty bag in a
sanitary landfill or by incineration or, if allowed by State
and local authorities, by burning. If burned, stay out of
smoke.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO
Proper Shipping Name : Not Regulated
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REGULATORY INFORMATION
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U.S. Federal Regulations
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No
M0000325 DuPont Page 9
Material Safety Data Sheet
(REGULATORY INFORMATION - Continued)
In the United States this product is regulated by the US
Environmental Protection Agency under the Federal Insecticide,
Fungicide and Rodenticide Act. It is a violation of federal law
to use this product in a manner inconsistent with its labeling.
EPA Reg. No. 352-581
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health :2
Flammability :1
Reactivity :0
NPCA-HMIS Rating
Health :2
Flammability :1
Reactivity :0
Personal Protection rating to be supplied by user depending on use
conditions.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : DuPont Crop Protection
Address : Wilmington, DE 19898
Telephone : 1-888-638-7668
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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