The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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DUPONT "VYDATE L" INSECTICIDE/NEMATICIDE
M0000057 Revised 9-JUL-2002
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"Vydate" is a registered trademark of DuPont.
Corporate MSDS Number : DU002105
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
OXAMYL 23135-22-0 24
(METHYL N鈥橬鈥?-DIMETHYL-N-[(METHYLCARBAMOYL)-
OXY]-1-THIOOXAMIMIDATE)
INERT INGREDIENTS 76
(INCLUDES PERCENTAGES OF THE FOLLOWING:)
*METHYL ALCOHOL 67-56-1 35-45
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
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HAZARDS IDENTIFICATION
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Emergency Overview
DANGER! POISON! Contains methanol. May be fatal or cause
blindness if swallowed. May be fatal if absorbed through
skin or inhaled.
Do not breathe vapors or spray mist. Do not get in eyes, on
M0000057 DuPont Page 2
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
skin, or on clothing. Pilot should not assist in the mixing
and loading operation.
WARNING SYMPTOMS (All Oxamyl Products)
Oxamyl poisoning produces effects associated with
anticholinesterase activity which may include weakness,
blurred vision, headache, nausea, abdominal cramps,
discomfort in the chest, constriction of pupils, sweating,
slow pulse, muscle tremors.
Potential Health Effects
SUPPLEMENTAL INFORMATION
METHANOL
Methanol is a skin, eye, and upper respiratory tract
irritant. Inhalation, ingestion, or skin absorption may
initially include: visual disturbances including blindness;
tempory nervous system depression wtih anaesthetic effects
such as dizziness, headache, confusion, incoordination, and
loss of consciousness; nonspecfic discomfort, such as
nausea, headache, or weakness; acidosis; irritation of the
upper respiratory passages; or fatality from gross
overexposure.
Individuals with preexisting diseases of the retina or liver
may have increased susceptibility to methanol toxicity.
Based on animal data, eye contact with Vydate L may cause eye
irritation with discomfort, tearing, or blurring of vision.
Based on animal data, skin contact with Oxamyl may cause
dermatitis with itching or rash. Skin permeation may occur in
amounts capable of producing the effects of systemic toxicity.
Based on animal data, skin contact, eye contact, inhalation or
ingestion exposures to Oxamyl may cause acute cholinesterase
depression characterized by weakness, nausea, headache, abdominal
cramps, excessive seating, salivation, tearing, constricted
pupils, blurred vision, muscle twitching and confusion. Higher
exposures may lead to loss of consciousness, convulsions, or
severe respiratory depression.
M0000057 DuPont Page 3
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
Individuals with pre-existing diseases of the central
nervous system or conditions which lower cholinesterase
levels may have increased susceptibility to the toxicity of
excessive exposure.
Effects that may occur due to the other components include
the following:
Short-term overexposure by inhalation may cause non-specific
effects such as headache, nausea, and weakness, and
irritation of the upper respiratory passages with coughing
and discomfort.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
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FIRST AID MEASURES
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First Aid
CONTAINS AN N-METHYL CARBAMATE THAT INHIBITS
CHOLINESTERASE.
IF SWALLOWED: Call poison control center or doctor
immediately for treatment advice. Drink 1 or 2 glasses
of water and induce vomiting by touching back of throat
with finger. Do not induce vomiting or give anything by
mouth to an unconscious person.
IF IN EYES: Hold eye open and rinse slowly and gently with
water for 15-20 minutes. Remove contact lenses, if present,
after the first 5 minutes, then continue rinsing eye. Call
a poison control center or doctor for treatment advice.
IF INHALED: Move person to fresh air. If person is not
breathing, call 911 or an ambulance, then give artificial
respiration, preferably by mouth-to-mouth, if possible. Call
a poison control center or doctor for further treatment
advice.
IF ON SKIN OR CLOTHING: Take off contaminated clothing.
Rinse skin immediately with plenty of water for 15-20
minutes. Call a poison control center or doctor for
treatment advice.
ATROPINE IS AN ANTIDOTE-SEEK MEDICAL ATTENTION AT ONCE IN
ALL CASES OF SUSPECTED POISONING.
If warning symptoms appear (see WARNING SYMPTOMS), get
medical attention. Have the product container or label
M0000057 DuPont Page 4
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
with you when calling a poison control center or doctor,
or going for treatment. You may also contact
1-800-441-3637 for emergency medical treatment information.
Notes to Physicians
WARNING SYMPTOMS: Oxamyl poisoning produces effects
associated with anticholinesterase activity which
may include weakness, blurred vision, headache,
nausea, abdominal cramps, discomfort in the chest,
constriction of pupils, sweating, slow pulse,
muscle tremors.
TREATMENT:Atropine sulfate should be used for treatment.
Administer repeated doses, 1.2 to 2.0 mg. intravenously
every 10 to 30 minutes until full atropinzation is achieved.
Maintain atropinzation until the patient recovers.
Artificial respiration or oxygen may be necessary. Allow no
further exposure to any cholinesterase inhibitor until
recovery is assured.
Do not use 2-PAM for exposure to VYDATE L alone. However,for
exposure to combinations of VYDATE L and organophosphorous
insecticides, 2-PAM may be used as required to supplement
the atropine sulfate treatment. Do not use morphine.
For medical emergencies involving this product, call toll
free 1-800-441-3637.
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FIRE FIGHTING MEASURES
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Flammable Properties
Flash Point : 23 C (73 F)
Method : Closed Cup
May be ignited by heat, sparks, or open flame.
Flammable liquid. Vapor forms explosive mixture with air.
Heating can release vapors which can be ignited.
Extinguishing Media
Water Spray, Foam, Dry Chemical, CO2.
Fire Fighting Instructions
Evacuate personnel to a safe area. Keep personnel removed and
upwind of fire. Wear self-contained breathing apparatus. Wear
full protective equipment. Shut off source of fuel, if possible
and without risk. Use water spray. Cool tank/container with
water spray. Runoff from fire control may be a pollution hazard.
M0000057 DuPont Page 5
Material Safety Data Sheet
(FIRE FIGHTING MEASURES - Continued)
If area is exposed to fire and conditions permit, let fire burn
itself out. Burning chemicals may produce by-products more toxic
than the original material. If product is on fire, wear
self-contained breathing apparatus and full protective equipment.
Use water spray. Control runoff.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Evacuate personnel, thoroughly ventilate area, use self-contained
breathing apparatus. Keep upwind of leak - evacuate until gas has
dispersed.
Emergency Response - Chemical resistant coveralls,
waterproof gloves, waterproof boots and face/eye protection.
If dusting occurs, use NIOSH approved respirator protection.
Initial Containment
Remove source of heat, sparks, flame, impact, friction or
electricity. Dike spill. Prevent material from entering sewers,
waterways, or low areas.
Follow applicable Federal, State/Provincial and Local laws/
regulations.
Spill Clean Up
Soak up with sawdust, sand, oil dry or other absorbent material.
Shovel or sweep up. Never return to container for reuse. Scoop
into bags or boxes with plastic or aluminum shovel.
Neutralize with solid sodium hydroxide at rate of 3 lbs.
per gallon spilled.
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HANDLING AND STORAGE
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Handling (Personnel)
Do not breathe vapor or mist. Do not get in eyes, on skin, or on
clothing. Wash thoroughly after handling. Wash clothing after
use. Do not store or consume food, drink or tobacco in areas
where they may become contaminated with this material.
USERS SHOULD: Wash hands before eating, drinking, chewing gum,
using tobacco or using the toilet.
M0000057 DuPont Page 6
Material Safety Data Sheet
(HANDLING AND STORAGE - Continued)
Remove clothing immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
Remove personal protective equipment immediately after handling
this product. Wash the outside of gloves before removing. As
soon as possible, wash thoroughly and change into clean clothing.
Handling (Physical Aspects)
Keep away from heat, sparks and flames.
Storage
Store above 0 C (32 F). Store product in original container only.
Do not store or consume food, drink or tobacco in areas where they
may become contaminated with this material. Do not contaminate
water, other pesticides, fertilizer, food or feed in storage.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Use only with adequate ventilation.
# Personal Protective Equipment
Some materials that are chemical resistant to this
product are listed below. If you want more options
follow the instructions for Category C on the EPA
chemical resistance category selection chart.
Applicators and other handlers must wear:
Coveralls over short-sleeved shirt and short pants.
Chemical-resistant gloves, such as barrier laminate or butyl
rubber or neoprene rubber or polyvinyl chloride (PVC) or
viton or nitrile rubber.
Chemical-resistant footwear, plus socks.
Protective eyewear.
Chemical-resistant headgear for overhead exposure.
Chemical-resistant apron when cleaning equipment, mixing or
loading.
A respirator with an organic vapor-removing cartridge with a
prefilter approved for pesticides (MSHA/NIOSH approval
number prefix TC-23C) or a canister approved for pesticides
(MSHA/NIOSH approval number prefix (TC-14G) or a Niosh
approved respirator with an organic vapor (OV) cartridge or
M0000057 DuPont Page 7
Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
canister with any R, P or HE prefilter.
Discard clothing or other absorbent materials that have been
drenched or heavily contaminated with this product鈥檚
concentrate. Do not reuse them. Follow manufacturer鈥檚
instructions for cleaning/maintaining PPE. If no such
instructions for washables, use detergent and hot water.
Keep and wash PPE separately from other laundry.
PPE required for early entry to treated areas that is
permitted under the Worker Protection Standard and that
involves contact with anything that has been treated, such
as plants, soil, or water, is:
Coveralls over short-sleeved shirt and short pants.
Chemical resistant gloves, such as barrier laminate or butyl
rubber or nitrile rubber or polyvinyl chloride or viton or
neoprene rubber.
Chemical resistant footwear plus socks.
Protective eyewear.
Chemical resistant headgear for overhead exposure.
Exposure Guidelines
Applicable Exposure Limits
OXAMYL
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 0.5 mg/m3, 8 Hr. TWA
1.0 mg/m3, 15 minute TWA
METHYL ALCOHOL
PEL (OSHA) : 200 ppm, 260 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 200 ppm, 8 Hr. TWA, Skin
STEL 250 ppm
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA, Skin
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Solubility in Water : Soluble
Odor : Slightly sulfurous
Form : Liquid
Color : Green, blue, or colorless depending on
region
Density : 0.97-0.98 g/cc
M0000057 DuPont Page 8
Material Safety Data Sheet
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Incompatible with strong acids or bases (slowly hydrolyzes).
Decomposition
Decomposition will not occur.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
Vydate L
Inhalation 4 hour LC50: 0.3 mg/L in rats
(Highly toxic)
Ingestion LD50: 10 mg/kg in male rats
Ingestion LD50: 9 mg/kg in female rats
(Highly toxic)
Skin absorption LD50: > 5000 mg/kg in rats
(Slightly toxic)
Vydate L is a slight eye irritant, but is not a skin irritant or
skin sensitizer in animals.
OXAMYL
Single or repeated skin contact with Oxamyl caused mild skin
irritation and cholinesterase inhibition (tremors, salivation,
watery eyes).
Single exposure to Oxamyl by ingestion caused signs of
cholinesterase inhibition, reduced weight gain, and temporary
alterations in clinical chemistry including liver enzymes and
glucose levels. Repeated or long-term exposure caused nonspecific
effects such as weight loss and irritation, as well as signs of
cholinesterase inhibition. Changes in liver enzyme levels have
been reported, but the structure of the liver itself appeared
normal. In an acute neurotoxicity study there was unequivocally
decreased blood and brain cholinesterase activity. The NOEL in
this study was 0.1 mg/kg.
M0000057 DuPont Page 9
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
Single exposure to 0.024 mg/L of Oxamyl by inhalation caused
tremors and lethargy. These signs were not observed in a group
exposed to 0.0049 mg/L. Plasma, red blood cell and brain
cholinesterase activity were decreased in rats exposed to 0.024
mg/L and to a lesser extent in rats exposed to 0.0049 mg/L.
Tests in animals demonstrate no carcinogenic activity. Tests in
some animals indicate that Oxamyl may have developmental toxicity,
but only at doses close to those which cause maternal toxicity.
The only reported effects were slightly reduced fetal weights and
fewer implantations. Tests in animals demonstrate no effect on
reproductive indices (mating, fertility, or gestation).
Reductions in litter size, pup weight and survival occurred only
at dose levels that also caused toxicity in the parental animals.
Oxamyl does not produce genetic damage in bacterial cell or
mammalian cultures, but has not been tested in animals.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity
"Vydate" L
96 hour LC50, rainbow trout: 12.4 ppm
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DISPOSAL CONSIDERATIONS
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# Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable federal, state/provincial, and
local regulations. Do not flush to surface water or sanitary
sewer system. Do not contaminate water, food, or feed by
storage or disposal. Pesticide wastes are acutely hazardous.
Improper disposal of excess pesticide, spray mixture,
or rinsate is a violation of Federal Law. If these
wastes cannot be disposed of by use according to label
instructions, contact your State Pesticide or
Environmental Control Agency, or the Hazardous Waste
representative at the nearest EPA Regional Office for
guidance.
M0000057 DuPont Page 10
Material Safety Data Sheet
(DISPOSAL CONSIDERATIONS - Continued)
Container Disposal
For Metal Containers (non aerosol): Triple rinse (or
equivalent) the container. Then offer for recycling or
reconditioning, or puncture and dispose of in a sanitary
landfill, or by other procedures approved by the State and
local authorities.
For Plastic Containers: Triple rinse (or equivalent). Then
offer for recycling or reconditioning, or puncture and
dispose of in a sanitary landfill, or incineration, or,
if allowed by state and local authorities, by burning.
If burned, stay out of smoke.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO
Proper Shipping Name : CARBAMATE
PESTICIDE,LIQUID,TOXIC,FLAMMABLE
(Oxamyl,Methanol)
Hazard Class : 6.1
UN No. : UN 2991
Packing Group :I
Subsidiary Hazard Class : 3
Marine Pollutant : MARINE POLLUTANT (24% Oxamyl)-Water or
Bulk
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REGULATORY INFORMATION
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U.S. Federal Regulations
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : Yes
Reactivity : No
Pressure : No
ADDITIONAL REGULATORY INFORMATION
Section 302 Extremely Hazardous Substance:
Oxamyl - Threshold Planning Quantity (TPQ)
(100/10,000 lbs)
SARA/CERCLA Reportable Quantity:
Oxamyl (1 lb)
Methyl alcohol (5000 lbs)
M0000057 DuPont Page 11
Material Safety Data Sheet
(REGULATORY INFORMATION - Continued)
RCRA Hazardous Waste: Oxamyl (P194)
REGULATORY CONTROLS
This product is registered under EPA/FIFRA regulations. It
is a violation of Federal Laws to use this product in any
manner inconsistant with its labeling. Read and follow all
label directions. This product is excluded from listing
requirements under EPA/TSCA.
EPA Reg. No. 352-372.
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health :2
Flammability :3
Reactivity :0
NPCA-HMIS Rating
Health :3
Flammability :3
Reactivity :0
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information
RESTRICTED USE PESTICIDE
Due to Acute Toxicity and Toxicity to Birds and Mammals.
For retail sale to and use only by Certified Applicators or
persons under their direct supervision and only for those
uses covered by the Certified Applicator鈥檚 certification.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : DuPont Crop Protection
Address : Wilmington,Delaware 19898
Telephone : 1-888-638-7668
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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