The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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DuPont "LANNATE" LV INSECTICIDE
M0000062 Revised 28-MAR-2003
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"Lannate" is a registered trademark of DuPont.
"DuPont" is a trademark of DuPont.
Corporate MSDS Number : DU003805
Tradenames and Synonyms
"LANNATE"LV
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
METHOMYL 16752-77-5 29
(S-METHYL-N-[(METHYLCARBAMOYL)OXY]THIO-
ACETIMIDATE)
INERT INGREDIENTS 71
(INCLUDES PERCENTAGES OF THE FOLLOWING:)
CYCLOHEXANONE 108-94-1 29-45
*METHANOL 67-56-1 <10
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
M0000062 DuPont Page 2
Material Safety Data Sheet
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HAZARDS IDENTIFICATION
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Emergency Overview
DANGER! POISON! CONTAINS METHANOL. Fatal if swallowed.
May cause blindness if swallowed. May be fatal if inhaled
or absorbed through eyes. Causes irreversible eye damage.
Do not get in eyes, on skin, or on clothing. Do not breathe
vapors or spray mist. Pilots should not assist in mixing
and loading operation.
WARNING SYMPTOMS
Methomyl poisoning produces effects associated with
anticholinesterase activity which may include weakness,
blurred vision, headache, nausea, abdominal cramps,
discomfort in the chest, constriction of pupils, sweating,
slow pulse, muscle tremors.
Potential Health Effects
Based on animal data, eye contact with Lannate LV may cause severe
eye irritation with discomfort, tearing, or blurring of vision.
Prolonged contact may cause eye corrosion or ulceration.
Based on animal data, skin contact with Lannate LV may cause
irritation with itching, burning, redness, swelling or rash.
Effects that may occur due to other components include the
following:
Short-term overexposure by inhalation may cause non-specific
effects such as headache, nausea and weakness, and irritation of
the upper respiratory passages with coughing and discomfort.
Skin, eye, inhalation or ingestion exposure to Methomyl may cause
acute cholinesterase depression characterized by nonspecific
discomfort, such as nausea, headache, weakness, cramps, excessive
sweating, salivation and tearing, constricted pupils, blurred
vision; muscle twitching, and confusion. Higher exposures may
lead to loss of consciousness; or convulsions and severe
respiratory depression.
Inhalation, ingestion or skin contact with Methyl Alcohol may
cause temporary mild depression of the central nervous system with
dizziness, confusion, incoordination or drowsiness followed by an
asymptomatic period usually ranging from 12 to 24 hours.
Metabolic acidosis develops followed by ocular toxicity (visual
disturbance including blindness). Other effects include
non-specific effects such as headache, nausea and weakness. Gross
overexposure may cause pathological changes in the liver and
kidneys; nerve damage with numbness, weakness or muscle rigidity;
tremors; convulsions; and fatality.
M0000062 DuPont Page 3
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
Increased susceptibility to the effects of overexposure may be
observed in persons with pre-existing disease of the nervous
system, visual system, liver, kidneys, and cardiovascular system.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
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FIRST AID MEASURES
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First Aid
THIS PRODUCT IS AN N-METHYL CARBAMATE INSECTICIDE.
IF SWALLOWED: Call a poison control center or doctor
immediately for treatment advice. Drink 1 or 2 glasses of
water and induce vomiting by touching back of throat with
finger. Do not induce vomiting or give anything by mouth to
an unconscious person.
IF IN EYES: Hold eye open and rinse slowly and gently with
water for 15-20 minutes. Remove contact lenses, if present,
after the first 5 minutes, then, continue rinsing eye. Call
a poison control center or doctor for treatment advice.
IF INHALED: Move person to fresh air. If person is not
breathing, call 911 or an ambulance, then give artificial
respiration, preferably by mouth-to-mouth, if possible.
Call a poison control center or doctor for treatment advice.
IF ON SKIN OR CLOTHING: Take off contaminated clothing.
Rinse skin immediately with plenty of water for 15-20
minutes. Call a poison control center or doctor for
treatment advice.
ATROPINE IS AN ANTIDOTE - SEEK MEDICAL ATTENTION AT ONCE IN
ALL CASES OF SUSPECTED POISONINGS.
If warning symptoms appear (see WARNING SYMPTOMS), get
medical attention. Have the product container or label with
you when calling a poison control center or doctor, or going
for treatment. You may also call 1-800-441-3637 for
emergency medical treatment information.
M0000062 DuPont Page 4
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Notes to Physicians
WARNING SYMPTOMS - Methomyl poisoning produces effects
associated with anticholinesterase activity, which may
include weakness, blurred vision, headache, nausea,
abdominal cramps, discomfort in the chest, constriction of
pupils, sweating, slow pulse, and muscle tremors.
TREATMENT - Atropine sulfate should be used for treatment.
Administer repeated doses, 1.2 to 2.0 mg intravenously every
10 to 30 minutes until full atropinization is achieved.
Maintain atropinization until the patient recovers.
Artificial respiration or oxygen may be necessary. Allow no
further exposure to any cholinersterase inhibitor until
recovery is assured.
Do not use 2-PAM for exposure to "Lannate" LV alone.
However, for exposure to combinations of "Lannate" LV and
organophosphorous insecticides, 2-PAM may be used as
required to supplement the atropine sulfate treatment as
described above. Do not use morphine.
For medical emergencies involving this product, call toll
free 1-800-441-3637.
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FIRE FIGHTING MEASURES
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Flammable Properties
Flash Point : 39-43 C (102-109 F)
Method : Closed Cup
Flammable limits in Air, % by Volume
LEL :5
UEL : 75
Autoignition : 305 C (581 F)
Combustible. Vapor forms explosive mixture with air. Heating can
release vapors which can be ignited.
Fire and Explosion Hazards:
Hazardous gases produced in a fire under conditions that
produce incomplete combustion may consist of SO2, NO2, CO2,
CH3NCO, HCN, CO, CS2. When combusted at higher temperatures
with sufficient oxygen, the following are greatly reduced:
CS2, CO, HCN, and CH3NCO.
Extinguishing Media
Water Spray, Foam, Dry Chemical, CO2.
M0000062 DuPont Page 5
Material Safety Data Sheet
(FIRE FIGHTING MEASURES - Continued)
Fire Fighting Instructions
Evacuate personnel to a safe area. Keep personnel removed and
upwind of fire. Wear self-contained breathing apparatus. Wear
full protective equipment. Shut off source of fuel, if possible
and without risk. Use water spray. Cool tank/container with
water spray. Fight fire from maximum distance, use extreme
caution as heat may decompose material and rupture containers.
If area is heavily exposed to fire and if conditions permit,
let fire burn itself out since water may increase the area
contaminated.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Initial Containment
Remove source of heat, sparks, flame, impact, friction or
electricity. Dike spill. Prevent material from entering sewers,
waterways, or low areas.
Spill Clean Up
Soak up with sawdust, sand, oil dry or other absorbent material.
Shovel or sweep up.
Accidental Release Measures
If product enters crevices and can not be removed, treat
with a sodium hydroxide solution and allow to stand 4 hours.
NOTE: Sodium hydroxide is caustic and causes burns. Do not
get in eyes, on skin or clothing.
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HANDLING AND STORAGE
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Handling (Personnel)
Do not breathe vapor or mist. Do not get in eyes, on skin, or on
clothing. Wash thoroughly after handling. Wash clothing after
use. Do not store or consume food, drink or tobacco in areas
where they may become contaminated with this material.
M0000062 DuPont Page 6
Material Safety Data Sheet
(HANDLING AND STORAGE - Continued)
USERS SHOULD: Wash hands before eating, drinking, chewing
gum, using tobacco or using the toilet. Remove clothing
immediately if pesticide gets inside. Then wash thoroughly
and put on clean clothing. Remove personal protective
equipment immediately after handling this product. Wash the
outside of gloves before removing.
Storage
Do not subject to temperatures below 32 deg. F. Store
product in original container only. Do not contaminate
water, other pesticides, fertilizer, food or feed in
storage. Not for use or storage in or around the home.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Use only with adequate ventilation. Keep container tightly closed.
Personal Protective Equipment
Some materials that are chemically resistant to this
product are listed below. If you want more options
follow the instructions for Category B on the EPA
chemical resistance category selection chart.
Applicators and other handlers must wear:
Long-sleevedshirt and long pants
Chemical-resistant gloves, such as barrier laminate or
赂butyl rubber
Shoes plus socks
Protective eyewear
For exposures in enclosed areas, a respirator with either an
organic vapor-removing cartridge with a prefilter approved
for pesticides (MSHA/NIOSH approval number prefix TC-23C),
or a canister approved for pesticides (MSHA/NIOSH approval
number prefix TC-14G), or NIOSH approved respirator with an
organic vapor (OV) cartridge or canister with any R, P, or
HE prefilter.
For exposures outdoors, a dust/mist filtering respirator
(MSHA/NIOSH approval number prefix TC-21C), or a NIOSH
approved respirator with any R, P, or HE prefilter.
Cleaners and repairers of application equipment must wear:
Long-sleeved shirt and long pants
Chemical resistant gloves
Chemical resistant footwear
Protective eyewear
Respirator as outlined above
M0000062 DuPont Page 7
Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
Chemical resistant apron
Discard clothing or other absorbent materials that have been
drenched or heavily contaminated with this product鈥檚
concentrate. Do not reuse them. Follow manufacturer鈥檚
instructions for cleaning/maintaining PPE. If no such
instructions for washables, use detergent and hot water.
Keep and wash PPE separately from other laundry.
PPE required for early entry to treated areas that is
permitted under the Worker Protection Standard and that
involves contact with anything that has been treated, such
as plants, soil or water is:
赂Coveralls
赂Chemical-resistant gloves, such as barrier laminate
赂or butyl rubber
赂Shoes plus socks
赂Protective eyewear
# Exposure Guidelines
Applicable Exposure Limits
METHOMYL
PEL (OSHA) : None Established
TLV (ACGIH) : 2.5 mg/m3, 8 Hr. TWA, A4
AEL * (DuPont) : None Established
CYCLOHEXANONE
PEL (OSHA) : 50 ppm, 200 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 20 ppm, 8 Hr. TWA, Skin, A3
STEL 50 ppm, Skin, A3
AEL * (DuPont) : 25 ppm, 8 & 12 Hr. TWA
STEL 50 ppm, 15 minute TWA
METHANOL
PEL (OSHA) : 200 ppm, 260 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 200 ppm, 8 Hr. TWA, Skin
STEL 250 ppm
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA, Skin
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Vapor Pressure : 57 mm Hg @ 25 C (77 F)
Solubility in Water : Soluble
Odor : Aromatic
Form : Liquid
Color : Amber
M0000062 DuPont Page 8
Material Safety Data Sheet
(PHYSICAL AND CHEMICAL PROPERTIES - Continued)
Specific Gravity : 1.021 @ 25C (77F)
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
None reasonably foreseeable.
Decomposition
Decomposes with heat.
Hazardous gases/vapors produced are toxic and/or noxious.
They may include sulfur oxides, methylisocyanate and HCN.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
Lannate LV
Inhalation 4 hour LC50: 1.1 mg/L in rats
(Moderately toxic)
Oral LD50: 89 mg/kg in male rats
Oral LD50: 49 mg/kg in female rats
(Highly to moderately toxic)
Skin absorption LD50: > 2000 mg/kg in rats
(Slightly to Moderately toxic)
Lannate LV is a slight skin irritant and a moderate to severe eye
irritant, but is not a skin sensitizer in animals.
METHOMYL
Ocular exposure with Methomyl caused pupillary constriction,
incoordination, tremors, convulsions, profuse salivation,
lethargy, rales, and/or fasciculations were also observed in
rabbits approximately 1 and 20 minutes after treatment with
10 mg of methomyl. Pupillary constriction was still evident
after 1 hour. These clinical signs are typical of
anticholinesterase activity. These effects were not present
the day after treatment.
Effects of a single inhalation exposure to Methomyl include
weight loss, respiratory irritation, diarrhea, lethargy, as
M0000062 DuPont Page 9
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
well as temporary decreased plasma cholinesterase activity,
abnormal gait, hyperactivity and tremors. Corneal opacity
was noted in one rat exposed to near-lethal concentrations.
Repeated exposures at 15 mg/m3 produced no histopathological
changes in lung, spleen, kidney, liver, brain, eyes or oral
and nasal mucosa.
Effects of a single dermal exposure to Methomyl include
rapid respiration, miosis and nervous system effects such as
tremors. Repeated exposure produced respiratory irritation
and labored breathing, and nervous system effects such as
miosis and depression.
A single ingestion exposure to Methomyl produced nervous
system effects as described for inhalation and skin
exposures. Repeated exposure at approximately 5 mg/kg
produced signs of nervous system effects (mild tremors)
without clinical or pathological signs of toxicity. Feeding
studies in rats and mice produced only mild effects having
no clear toxicological significance. Long-term feeding
studies at dietary levels up to 1,000 ppm produced lowered
red blood counts and hematocrit, indications of nervous
system effects and histopathological changes in kidneys,
spleen, liver and bone marrow.
In a 91-day oral Neurotoxicity study in rats, most of the
effects observed appeared to be acute in nature. There were
no morphological changes in the nervous system. The NOEL in
this study was 150 ppm, based on clinical and biochemical
evidence of cholinesterase activity inhibition.
Tests in animals demonstrate no carcinogenic, developmental,
or reproductive toxicity. (One test in mice reports
abnormal sperm morphology).
Methomyl does not produce genetic damage in animals or in
bacterial and mammalian cell cultures.
CYCLOHEXANONE
Single dermal exposure to lethal doses of Cyclohexanone
caused central nervous system depression, tremors,
hypothermia and skin necrosis. Single exposure to
Cyclohexanone by ingestion caused narcosis. Repeated and
long-term exposure caused decreased weight gain.
Single exposure to Cyclohexanone by inhalation caused
irritation of mucous membranes, narcosis and hypothermia.
Repeated exposure caused conjunctival irritation,
salivation, narcosis, slight degenerative changes in the
liver and kidneys, effect on sense of smell and nonspecific
effects such as weight loss.
In some animals, Cyclohexanone may have elicited a weak
M0000062 DuPont Page 10
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
carcinogenic response. Animal data show fetotoxicity but
only at exposure levels producing other toxic effects in the
adult animal. Reversible depression of fertility was
observed in second-generation male rats exposed to 1400 ppm.
Cyclohexanone produces genetic damage in bacterial and
mammalian cell cultures. Animal data indicate that
Cyclohexanone does not cause genetic damage in animals nor
permanent genetic damage in reproductive cells of mammals
(does not cause heritable genetic damage).
METHANOL
Eye contact with Methyl Alcohol caused clouding of the eye
(corneal opacity).
Repeated skin contact with higher concentrations of Methyl
Alcohol caused some mortality.
Single exposure by ingestion caused narcosis, liver effects,
and hypothermia. Repeated exposure caused pathological
changes of the eyes and acidosis.
Repeated exposure by inhalation caused irritation of the
eyes and blindness.
No animal data are available to define the carcinogenicity
of Methyl Alcohol. Exposure of pregnant rats shows the
following developmental effects: reduced birth weight, bone
abnormalities, and behavioral abnormalities. Exposure of
pregnant mice shows the following developmental effects:
reduced birth weight, resorption, and bone abnormalities.
No adequate animal data are available to define the
reproductive effects of Methyl Alcohol. Tests have shown
that Methyl Alcohol does not cause genetic damage in
bacterial or mammalian cell cultures, or in animals. Methyl
Alcohol has not been tested for its ability to cause
permanent genetic damage in reproductive cells of mammals
(not tested for heritable genetic damage).
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
AQUATIC TOXICITY:
METHOMYL
96 hour LC50 - Bluegill sunfish: 0.72 mg/L.
MATC, fathead minnows : 104 ug/L
CYCLOHEXANONE
96 hour LC50 - Fathead minnows: 527 mg/L.
METHANOL
96 hour LC50 - Fathead minnows: 28,100 mg/L
M0000062 DuPont Page 11
Material Safety Data Sheet
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DISPOSAL CONSIDERATIONS
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Waste Disposal
This product is toxic to fish, birds and other wildlife.
Keep out of any body of water. Do not contaminate water by
cleaning of equipment or disposal of wastes. Do not
discharge effluent containing this product into lakes,
streams, ponds, estuaries, oceans, or other waters unless in
accordance with the requirements of a National Pollutant
Discharge Elimination System (NPDES) permit and the
permitting authority has been notified in writing prior to
discharge. Do not discharge effluent containing this
product to sewer systems without previously notifying the
local sewage treatment plant authority. For guidance,
contact your State Water Board or Regional Office of the
EPA."
Treatment, storage, transportation and disposal must be in
accordance with applicable Federal, State/Provincial, and
Local regulations. Do not flush to surface water or
sanitary sewer system.
Do not contaminate water, food, or feed by disposal.
Pesticide wastes are acutely hazardous. Improper disposal
of excess pesticide, spray mixture, or rinsate is a
violation of Federal Law. If these wastes cannot be
disposed of by us according to label instructions,
contact your State Pesticide or Environmental Control
Agency, or the Hazardous Waste representative at the
nearest EPA Regional Office for guidance.
Container Disposal
For Metal Containers (non aerosol): Triple rinse (or
equivalent) the container. Then offer for recycling or
reconditioning, or puncture and dispose of in a sanitary
landfill, or by other procedures approved by the State and
local authorities.
For Plastic Containers: Triple rinse (or equivalent). Then
offer for recycling or reconditioning, or puncture and
dispose of in a sanitary landfill, or incineration, or,
if allowed by State and local authorities, by burning.
If burned, stay out of smoke.
M0000062 DuPont Page 12
Material Safety Data Sheet
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO
Proper Shipping Name : CARBAMATE PESTICIDE, LIQUID, TOXIC,
FLAMMABLE
(methomyl in cyclohexanone)
Hazard Class : 6.1
UN No. : UN 2991
Special Information : Marine Pollutant (water or bulk)
Flash Point: 39 deg C (102.2 deg F)
Subsidiary Hazard Class : 3
Packing Group : II
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REGULATORY INFORMATION
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U.S. Federal Regulations
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : Yes
Reactivity : No
Pressure : No
ADDITIONAL REGULATORY INFORMATION
Section 302 Extremely Hazardous Substance:
Methomyl - Threshold Planning Quantity (TPQ)
(500/10,000 lbs)
SARA/CERCLA Reportable Quantity:
Methomyl (100 lbs)
Methanol (5000 lbs)
Cyclohexanone (5000 lbs)
REGULATORY CONTROLS:
This product is registered under EPA/FIFRA regulations. It
is a violation of Federal Laws to use this product in any
manner inconsistant with its labeling. Read and follow all
label directions. This product is excluded from listing
requirements under EPA/TSCA.
EPA Reg. No. 352-384
M0000062 DuPont Page 13
Material Safety Data Sheet
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health :2
Flammability :2
Reactivity :0
NPCA-HMIS Rating
Health :3
Flammability :2
Reactivity :0
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information
RESTRICTED USE PESTICIDE
Due to High Acute Toxicity to Humans
For retail sale and use only by Certified Applicators or
persons under their direct supervision and only for those
uses covered by the Certified Applicator鈥檚 certification.
Direct supervision for this product requires the certified
applicator to review federal and supplemental label
instructions with all personnel prior to application,
mixing, loading, or repair or cleaning of application
equipment.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : DuPont Crop Protection
Wilmington DE 19898
Telephone : 1-888-638-7668
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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