The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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DuPont VYDATE C-LV INSECTICIDE/NEMATICIDE
M0000454 Revised 18-JUL-2003
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"VYDATE" is a registered trademark of DuPont.
"DuPont" is a trademark of DuPont.
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
OXAMYL 23135-22-0 42
(METHYL N鈥?,N鈥?-DIMETHYL-N-[(METHYLCARBAMOYL)-
OXY]-1-THIOOXAMIMIDATE)
INERT INGREDIENTS 58
(INCLUDES PERCENTAGES OF THE FOLLOWING:)
CYCLOHEXANONE 108-94-1 25-29
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HAZARDS IDENTIFICATION
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Emergency Overview
DANGER! POISON! Fatal if swallowed or inhaled. May be
fatal if absorbed through the eyes. Causes irreversible eye
damage. May be harmful if absorbed through the skin. Do
not breathe vapors. Do not get in eyes, on skin, or on
clothing.
WARNING SYMPTOMS (All Oxamyl Products)
Oxamyl poisoning produces effects associated with
anticholinesterase activity which may include weakness,
M0000454 DuPont Page 2
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
blurred vision, headache, nausea, abdominal cramps,
discomfort in the chest, constriction of pupils, sweating,
slow pulse, muscle tremors.
Potential Health Effects
SUPPLEMENTAL INFORMATION
CYCLOHEXANONE
The compound is a skin irritant, is a severe eye irritant,
but is not a skin sensitizer in animals. Exposure to high
concentrations may result in temporary central nervous
system depression with symptoms of dizziness, headache,
confusion, incoordination and loss of consciousness. While
tests of bacterial and mammalian cells in culture indicate
genetic damage, studies in animals showed neither genetic
damage nor heritable genetic damage.
Based on animal data, eye contact with Vydate C-LV may cause eye
irritation with discomfort, tearing, or blurring of vision.
Based on animal data, skin contact with Oxamyl may cause
dermatitis with itching or rash. Skin permeation may occur in
amounts capable of producing the effects of systemic toxicity.
Based on animal data, skin contact, eye contact, inhalation or
ingestion exposures to Oxamyl may cause acute cholinesterase
depression characterized by weakness, nausea, headache, abdominal
cramps, excessive seating, salivation, tearing, constricted
pupils, blurred vision, muscle twitching and confusion. Higher
exposures may lead to loss of consciousness, convulsions, or
severe respiratory depression.
Effects that may occur due to other components include the
following:
Short-term overexposure by inhalation may cause non-specific
effects such as headache, nausea and weakness, and irritation of
the upper respiratory passages with coughing and discomfort.
Individuals with pre-existing diseases of the central
nervous system or conditions which lower cholinesterase
levels may have increased susceptibility to the toxicity
of excessive exposures.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
M0000454 DuPont Page 3
Material Safety Data Sheet
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FIRST AID MEASURES
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First Aid
CONTAINS AN N-METHYL CARBAMATE THAT INHIBITS
CHOLINESTERASE.
IF SWALLOWED: Call poison control center or doctor
immediately for treatment advice. Drink 1 or 2 glasses
of water and induce vomiting by touching back of throat
with finger. Do not induce vomiting or give anything by
mouth to an unconscious person.
IF IN EYES: Hold eye open and rinse slowly and gently with
water for 15-20 minutes. Remove contact lenses, if present,
after the first 5 minutes, then continue rinsing eye. Call
a poison control center or doctor for treatment advice.
IF INHALED: Move person to fresh air. If person is not
breathing, call 911 or an ambulance, then give artificial
respiration, preferably by mouth-to mouth, if possible. Call
a poison control center or doctor for further treatment
advice.
IF ON SKIN OR CLOTHING: Take off contaminated clothing.
Rinse skin immediately with plenty of water for 15-20
minutes. Call a poison control center or doctor for
treatment advice.
ATROPINE IS AN ANTIDOTE--SEEK MEDICAL ATTENTION AT ONCE IN
ALL CASES OF SUSPECTED POISONING
If warning symptoms appear (see WARNING SYMPTOMS), get
medical attention. Have the product container or label
with you when calling a poison control center or doctor,
or going for treatment. You may also contact 1-800-441-3637
for emergency medical treatment information.
Notes to Physicians
NOTE TO PHYSICIAN:
WARNING SYMPTOMS- Oxamyl poisoning produces effects
associated with anticholinesterase activity, which may
include weakness, blurred vision, headache, nausea,
abdominal cramps, discomfort in the chest, constriction
of pupils, sweating, slow pulse, and muscle tremors.
TREATMENT- Atropine sulfate should be used for treatment.
Administer repeated doses, 1.2 to 2.0 mg intravenously
every 10 to 30 minutes until full atropinization is
achieved. Maintain atropinization until the patient
recovers. Artificial respiration or oxygen may be
necessary. Allow no further exposure to any
cholinesterase inhibitor until recovery is assured.
M0000454 DuPont Page 4
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Do not use morphine or 2-PAM. For medical emergencies
involving this product, call toll-free 1-800-441-3637.
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FIRE FIGHTING MEASURES
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Flammable Properties
Flash Point : 51.7 C (125.1 F)
Method : Closed Cup
Heating can release vapors which can be ignited.
Extinguishing Media
Water Spray, Dry Chemical.
Fire Fighting Instructions
Evacuate personnel to a safe area. Keep personnel removed and
upwind of fire. Wear self-contained breathing apparatus. Wear
full protective equipment. Use water spray. Cool tank/container
with water spray. Runoff from fire control may be a pollution
hazard.
If area is exposed to fire and conditions permit, let fire burn
itself out. Burning chemicals may produce by-products more toxic
than the original material. If product is on fire, wear
self-contained breathing apparatus and full protective equipment.
Use water spray. Control runoff.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Evacuate personnel, thoroughly ventilate area, use self-contained
breathing apparatus.
Emergency Response - Chemical resistant coveralls,
waterproof gloves, waterproof boots and face/eye protection.
If dusting occurs, use NIOSH approved respirator protection.
Initial Containment
Dike spill. Prevent material from entering sewers, waterways, or
low areas.
Follow applicable Federal, State/Provincial and Local laws/
regulations.
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Material Safety Data Sheet
(ACCIDENTAL RELEASE MEASURES - Continued)
Spill Clean Up
Soak up with sawdust, sand, oil dry or other absorbent material.
Shovel or sweep up. Never return to container for reuse. Scoop
into bags or boxes with plastic or aluminum shovel.
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HANDLING AND STORAGE
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Handling (Personnel)
Do not breathe vapor or mist. Do not get in eyes, on skin, or on
clothing. Wash thoroughly after handling. Wash clothing after
use. Do not store or consume food, drink or tobacco in areas
where they may become contaminated with this material.
USERS SHOULD: Wash hands before eating, drinking, chewing gum,
using tobacco or using the toilet.
Remove clothing immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
Remove personal protective equipment immediately after handling
this product. Wash the outside of gloves before removing. As
soon as possible, wash thoroughly and change into clean clothing.
Handling (Physical Aspects)
Keep away from heat, sparks and flames.
Storage
Store above 0 C (32 F). Store product in original container only.
Do not contaminate water, other pesticides, fertilizer, food or
feed in storage. Do not store or consume food, drink or use
tobacco in areas where they may become contaminated with this
material. Do not store in or around the home.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Use only with adequate ventilation. Keep container tightly
closed. Do not use or store near heat or open flame.
Personal Protective Equipment
Always follow the label instructions when handling this product.
Applicators and other handlers must wear:
Coveralls over short-sleeved shirt and short pants.
Chemical-resistant footwear plus socks.
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Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
Chemical-resistant gloves, such as barrier laminate or butyl
rubber.
Protective eyewear.
Chemical-resistant headgear for overhead exposure.
Chemical-resistant apron when mixing, or loading, or cleaning
equipment.
A respirator with an organic vapor-removing cartridge with a
prefilter approved for pesticides (MSHA/NIOSH approval number
prefix TC-23C), or a canister approved for pesticides (MSHA/NIOSH)
approval number prefix TC-14G) or a NIOSH approved respirator with
an organic vapor (OV) cartridge or canister with any R, P or HE
prefilter.
Discard clothing or other absorbent materials that have been
drenched or heavily contaminated with this product鈥檚 concentrate.
Do not reuse them. Follow manufacturer鈥檚 instructions for
cleaning/maintaining PPE. If no such instructions for washables,
use detergent and hot water. Keep and wash PPE separately from
other laundry.
PPE required for early entry to treated areas that is permitted
under the Worker Protection Standard and that involves contact
with anything that has been treated, such as plants, soil, or
water is:
Coveralls over short-sleeved shirt and short pants.
Chemical-resistant gloves, such as barrier laminate or butyl
rubber.
Chemical-resistant footwear plus socks.
Protective eyewear.
Chemical-resistant headgear for overhead exposure.
# Exposure Guidelines
Applicable Exposure Limits
OXAMYL
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 0.05 mg/m3, 8 & 12 Hr. TWA
CYCLOHEXANONE
PEL (OSHA) : 50 ppm, 200 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 20 ppm, 8 Hr. TWA, Skin, A3
STEL 50 ppm, Skin, A3
AEL * (DuPont) : 25 ppm, 8 & 12 Hr. TWA
STEL 50 ppm, 15 minute TWA
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
M0000454 DuPont Page 7
Material Safety Data Sheet
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Vapor Pressure : 14.1 mm Hg @ 20 C (68 F)
Solubility in Water : Miscible
Odor : Aromatic
Form : Liquid
Color : Blue
Specific Gravity : 1.082 @ 25C (77F)
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
None reasonably foreseeable.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
Vydate C-LV
Inhalation 4 hour LC50: 0.11 mg/L in rats
(Highly toxic)
Ingestion LD50: 9.1 mg/kg in rats
(Highly toxic)
Skin absorption LD50: > 5000 mg/kg in rats
(Slightly toxic)
Vydate C-LV is an eye irritant, but is not a skin irritant or skin
sensitizer in animals.
OXAMYL
Single or repeated skin contact with Oxamyl caused mild skin
irritation and cholinesterase inhibition (tremors, salivation,
watery eyes).
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Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
Single exposure to Oxamyl by ingestion caused signs of
cholinesterase inhibition, reduced weight gain, and temporary
alterations in clinical chemistry including liver enzymes and
glucose levels. Repeated or long-term exposure caused nonspecific
effects such as weight loss and irritation, as well as signs of
cholinesterase inhibition. Changes in liver enzyme levels have
been reported, but the structure of the liver itself appeared
normal. In an acute neurotoxicity study there was unequivocally
decreased blood and brain cholinesterase activity. The NOEL in
this study was 0.1 mg/kg.
Single exposure to 0.024 mg/L of Oxamyl by inhalation caused
tremors and lethargy. These signs were not observed in a group
exposed to 0.0049 mg/L. Plasma, red blood cell and brain
cholinesterase activity were decreased in rats exposed to 0.024
mg/L and to a lesser extent in rats exposed to 0.0049 mg/L.
Tests in animals demonstrate no carcinogenic activity. Tests in
some animals indicate that Oxamyl may have developmental toxicity,
but only at doses close to those which cause maternal toxicity.
The only reported effects were slightly reduced fetal weights and
fewer implantations. Tests in animals demonstrate no effect on
reproductive indices (mating, fertility, or gestation).
Reductions in litter size, pup weight and survival occurred only
at dose levels that also caused toxicity in the parental animals.
Oxamyl does not produce genetic damage in bacterial cell or
mammalian cultures, but has not been tested in animals.
CYCLOHEXANONE
Single dermal exposure to lethal doses of Cyclohexanone caused
central nervous system depression, tremors, hypothermia and skin
necrosis. Single exposure to Cyclohexanone by ingestion caused
narcosis. Repeated and long term exposure caused decreased weight
gain.
Single exposure to Cyclohexanone by inhalation caused irritation
of mucous membranes, narcosis and hypothermia. Repeated exposure
caused conjunctival irritation, salivation, narcosis, slight
degenerative changes in the liver and kidneys, effect on sense of
smell and nonspecific effects such as weight loss.
In some animals Cyclohexananone may have elicited a weak
carcinogenic response. Animal data show fetotoxicity but only at
exposure levels producing other toxic effects in the adult animal.
Reversible depression of fertility was observed in second
generation male rates exposed to 1400 ppm. Cyclohexananone
produces genetic damage in bacterial and mammalian cell cultures.
Animal data indicate that Cyclohexananone does not cause genetic
damage in animals nor permanent genetic damage in reproductive
cells of mammals (does not cause heritable genetic damage).
M0000454 DuPont Page 9
Material Safety Data Sheet
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
AQUATIC TOXICITY:
OXAMYL
96 hour LC50 - Rainbow trout: 4.2 mg/L.
96 hour LC50 - Sheepshead minnow: 2.6 mg/L.
CYCLOHEXANONE
96 hour LC50 - Fathead minnows: 527 mg/L
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations. Do not flush to surface water or sanitary sewer
system.
Do not contaminate water, food, or feed by storage or
disposal. Pesticide wastes are acutely hazardous. Improper
disposal of excess pesticide, spray mixture, or rinsate is a
violation of Federal Law. If these wastes cannot be
disposed of by use according to label instructions, contact
your State Pesticide or Environmental Control Agency, or the
Hazardous Waste representative at the nearest EPA Regional
Office for guidance.
CONTAINER DISPOSAL
Triple rinse (or equivalent) the container. Then offer for
recycling or reconditioning, or puncture and dispose of in a
sanitary landfill, or, if allowed by State and Local
authorities, by burning. If burned, stay out of smoke.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO
Proper Shipping Name : CARBAMATE PESTICIDE, LIQUID, TOXIC
FLAMMABLE(OXAMYL, CYCLOHEXANONE)
Hazard Class : 6.1
UN No. : UN 2991
Marine Pollutant : MARINE POLLUTANT(42% Oxamyl)-Water or
Bulk
Subsidiary Hazard Class : 3
Packing Group :I
M0000454 DuPont Page 10
Material Safety Data Sheet
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REGULATORY INFORMATION
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U.S. Federal Regulations
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No
ADDITIONAL REGULATORY INFORMATION
Section 302 Extremely Hazardous Substance:
Oxamyl - Threshold Planning Quantity (TPQ)
(100/10,000 lb)
SARA/CERCLA Reportable Quantity:
Oxamyl (1 lb)
Cyclohexanone (5000 lb)
RCRA Hazardous Waste: Oxamyl (P194)
REGULATORY CONTROLS
This product is registered under EPA/FIFRA regulations. It
is a violation of Federal Laws to use this product in any
manner inconsistant with its labeling. Read and follow all
label directions. This product is excluded from listing
requirements under EPA/TSCA.
EPA Reg. No. 352-532.
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health :2
Flammability :1
Reactivity :0
NPCA-HMIS Rating
Health :3
Flammability :1
Reactivity :0
Personal Protection rating to be supplied by user depending on use
conditions.
M0000454 DuPont Page 11
Material Safety Data Sheet
(Continued)
Additional Information
RESTRICTED USE PESTICIDE
Due to Acute Toxicity and Toxicity to Birds and Mammals. For
retail sale to and use only by Certified Applicators or
persons under their direct supervision and only for those
uses covered by the Certified Applicator鈥檚 Certification.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS: DuPont Crop Protection
Address : Wilmington, DE 19898
Telephone : 1-888-638-7668
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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