MSDS PAGE: CAS 50-00-0 67-56-1 64-18-6 7732-18-5 MSDS celanese

产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004

材料安全资料�?
1. 产品与公司识别资�?

Product:37% 甲醛/9-12% 甲醇, 溶液
MSDS 号码: 155
材料号码:80155

Celanese Pte Ltd
501 Orchard Road
Wheelock Place #11-01
Singapore 238880
Tel No: (65) 67331767

运输紧�?�情况电话号码：
+ (65) 66639259 (Operations Room direct dial)
+ (65) 62656917 (Operations Room direct dial)
+ (65) 62650177(Switchboard, ask for Operations Room)

or fax request to
+(65) 62644190 (Facsimile to Operations Room)
+(65) 62664696 (Facsimile to Operations Room)

or email to
opsroom@semco.psa.com.sg

or Call CHEMTREC 703 527 3887 (USA), collect calls accepted
"+" = International Dialing Access Code

产品使用:尿素和三聚氰胺甲醛树脂中间物；酚醛树脂；乙炔化学品；聚醛树脂�?

2. 成分/成分资料

成分及化学文摘服务处号�?? 重量% OSHA 规定状况:
成分及化学文摘服务处
号�??
甲醛 50-00-0 37 - 37.5 危险
甲醇 67-56-1 9 - 12 危险
甲酸 64-18-6 0.02 危险

Water (CAS 7732-18-5), wt. %:50.5 - 54

An equilibrium mixture of formaldehyde, methanol, and water with the nominal composition listed above.

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产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
3. 危险识别

紧�?�情况：
危险!
造成皮肤、眼睛�?�消化道及呼吸道灼伤�?
长期及反复皮肤接触可造成死亡或失明�??
吞入可能致命或导致失明�??
易燃液体和蒸气�??
造成呼吸道�?�咽喉�?�皮肤和眼睛刺激�?
吸入有害�?
可能导致过敏性呼吸及皮肤反应�?
致癌危险。含有可能致癌材料�?�致癌风险决定于接触时间长短及程度�??

产品说明

外貌: 透明、无色液体�??
味道: 强烈、刺鼻�?�独氐钠�?丁�??蘋DOR020 淡辛辣�?�脂肪酸气味�?

潜在健康影响
暴露途径: 皮肤、眼睛�?�吸入�?�咽下�??

实时影响
皮肤: 会引起皮肤灼伤�?? 可能会引起皮肤过敏反应�?? 如果从皮肤吸收会有害�?
暴露的征状可能包括﹕
中央神经系统压抑�?引起的头痛�?�木僵�?�不协调或奇怪的举止或昏迷�??
皮肤发红或变色�?�肿、痒、烧痛或起泡�?
皮肤长期�?/或重复与浸甲醇的材料接触会产生中毒效果�?�包括视力受损和死亡�?

眼睛: 暴露于液�? 会引起严重眼睛灼伤�?�损伤不可�?�转�? 暴露于气�? 会刺�?眼睛�?
暴露的征状可能包括﹕ 眼睛刺激、灼烧的感觉、痛、流眼泪�?/或视力改变�??

吸入: 会引起呼吸道刺激�? 如果吸入会损伤�?? 可能会引起过敏呼吸反应�??
暴露的征状可能包括﹕
中央神经系统压抑�?引起的呕心�?�头晕�?�头痛�?�木僵�?�不协调或奇怪的举止或昏迷�??
流鼻水�?�嘶哑�?�咳嗽�?�胸痛和呼吸困难�? 肺积�?(肺水�?)—征状可能延迟数小时�?
对视力有不良影响�?

咽下: 会引起消化道烧伤�? 如果咽下会有害�?? 暴露的征状可能包括﹕
中央神经系统压抑�?引起的呕心�?�头晕�?�头痛�?�木僵�?�不协调或奇怪的举止或昏迷�??
呕心、呕吐�?�失去食欲�?�刺�?肠胃�?/或腹泻�?? 严重损伤口�?�喉、食管和/或胃�?

生殖: 根据动物数据，可能会引起不良的生殖影响�??

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产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
致癌�?: 根据实验室嚙齿动物研究及有限的人类数据，长期或重复呼吸�?�过分受甲醛暴露可能
会导致鼻肿瘤。人类受甲醛暴露的研究显示混合的结果，指出白�?病及以下状况与甲
醛暴露有关﹕
甲醛是：
列为OSHA致癌物﹕ 被NTP列为预期的致癌物
listed as carcinogenic to humans, IARC Group I, based on sufficient human
evidence for nasopharyngeal cancer and sufficient evidence in experimental
animals

对特定器官的影响: 过度（长期或反复）接触可导致�?
中枢神经系统压抑
眼睛受伤
消化道损�?
呼吸道损�?
过敏反应及皮肤局部刺�?
皮肤损伤�?
生殖系统受损
过敏性呼吸反�?
Nasal track

�?般认为在暴露后会使病情恶化的大量接触该化学品可能会对患有下列急�?�或慢�?�器官疾病的病人有不利影响：
病况: 呼吸�?
皮肤
眼睛
中枢神经系统

有关详情，参�?:
�?4部分 �? 急救措施
�?5部分 �? 灭火措施
�?6部分 �? 意外释放措施
�?8部分 �? 暴露控制/个人保护
�?9部分 �? 物理与化学特�?
�?10部分 �? 稳定性与反应�?

4. 急救措施

皮肤: 立即用大量清水冲洗皮肤至�?15分钟，并同时脱下污染的衣服和鞋子。立即寻求治�?
。衣服应洗干�?后才能再穿�?�污染的鞋子应毁灭�??

眼睛: 立即用大量清水冲洗眼睛至�?15分钟。如果有戴隐形眼镜并可以轻易取下时，应将�?
取下。立即寻求治疗�??

吸入: 移往空气清新处�?�如果停止呼吸，应施人工呼吸。如果呼吸困难，应给氧气。联络医
生�??

咽下: 切勿引起呕吐。立即寻求治疗�?�如果受害�?�完全清 �?
，给他喝�?杯水。切勿喂昏迷�? 人任何东西�??

医生注意: 观察延缓肺水肿�?? 呼吸道暴露后可能会导致化学肺炎�??
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运输紧�?�情�?:703 527 3887 (USA) CHEMTREC, collect calls accepted, 24 hrs/day
3 of 17
产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004

5. 灭火措施

NFPA: Health: 3 Flammability: 2 Reactivity: 0

易燃特�??

闪点(测试方法)�? 56 C (133 F) to 64 C (147 F) (SETA)

易燃限度，在空气，容�?%
上限: 73 % (Formaldehyde)
36.5 % (Methanol at 25 deg C)
Not Applicable (Water)
下限: 7 % (Formaldehyde)
5.5% (Methanol at 25 deg C)
Not Applicable (Water)

自动点燃温度: 300 C (572 F) (Formaldehyde)
385 C (725 F) (Methanol)

燃烧产品�? �?氧化碳�??

灭火媒介: 大火使用酒精类的水溶成膜泡沫�? 小火使用二氧化碳或干化学品�??

消防说明应用水冷却暴露在火中的建筑和槽�?�洒水可用于降低火势，并将溢出物�?释成不易�?
的混合物�?
将人员撤离火源至迎风地点。如果有可能暴露在蒸气下或有可燃烧的产品存在，应�?
全套消防装备和NIOSH核准的独立呼吸装备�?�氧化化学品在着火的情况下可能会加�?�燃
烧的速度�?

消防环保问题溢出的水和蒸气云可能有腐�?性�?�用堤并收集用于灭火的水，中和后才释放�??
可使用水雾流控制蒸气和燃烧气体�??
再用储藏库设备和其它灭火设备前应完全清除污染�?

6. 意外释放措施

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产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
溢出或泄漏说�? 排除点火源�??
参见�?8部分有关适当的人员保护设备�?�用土堤或非易燃的吸收剂隔离溢出物，使污�?
保持在最小的范围内�?? 水雾流可以减少蒸气�??
如果有起火的可能，应使用酒精类的水溶成膜泡沫来覆盖溢出物，或用水雾流分散�?
气�??
应避免流入下水道及�?�往水道的沟渠�?�若州及地方有规定，应�?�知地方当局。将泄漏
的容器置于�?�风良好处�?? 使用氨基磺酸或重亚硫酸钠中和�?
使用非燃烧的吸收剂清除或用少许水冲洗小规模的溢出物�?�使用非燃烧的堤或吸收剂
控制大规模的溢出物�?�用真空吸除或扫除干�?�?

在美国境内，如果�?24小时内释放出的分量相等于或超于下列应报告的分量时，应�?
电�?�全国响应中心�??(National Response Center) (800-424-
8802)和�?�当的州及当地机关﹕
270 lbs. of the material as is; based on a Reportable Quantity of 100 lbs.
for formaldehyde.

驱散不必要在场的人；隔离危险地区并拒绝任何人进入。保持在迎风的位置；避开�?
的地区�??
如果火灾涉及到运输罐、火车罐车或卡车罐车，应在各个方向上隔离800米（0.5英里
）�??
如果情况有必要应撤离顺风地区以预防暴露，并让蒸气或烟消散。某些情况的溢出�?
可能使相当远距离的顺风地区暴露于有毒或可燃烧的浓度�??

7. 处理与储�?

处理: 在�?�风足够的环境下使用�?
不使用时应将容器关紧。打�?容器时，应小心谨慎让累积的压力�?�出。避免吸入蒸�?
。避免与眼睛、皮肤或衣服接触。处理后应用肥皂和水彻底洗干�?。沾污的衣服应彻
底清除污染后才再使用。污染的皮革衣物应毁灭�??

储藏: 不使用时，将�?有容器关紧�?�储存在没有阳光照射和不可渗透的地板上�??
请勿与不兼容的材料储存�?�参见�?�第10部分，稳定�?�与反应性�?��??

8. 暴露控制/个人保护

工程控制 �?般或�?释�?�风作为雇员暴露的唯�?控制方法通常是不足够的�?��?�常优先选择的是�?
部�?�风�?

应随时准备好安全淋浴和洗眼设备�??
个人保护设备
皮肤保护: 穿�?�不过的衣服和手套以便预防接触�?�建议使用丁基橡胶�?�视情况，如果有足够的降
解和渗�?�资料，可使用其它保护材料�?�如果在使用本化学品的同时使用其它化学品�?
选择的材料应能保护所有使用的化学品�??

眼睛/脸部保护: 如有可能接触眼睛时应戴化学护目镜�?
如果可能喷洒到脸上时，除了戴护目镜外还应戴面罩�??

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运输紧�?�情�?:703 527 3887 (USA) CHEMTREC, collect calls accepted, 24 hrs/day
5 of 17
产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
呼吸道保�?: 根据工作场所的污染程度及防毒面罩的工作限度，使用经�?�全国职业安全与保健学会
�?(NIOSH)
核准使用的防毒面罩�?�以下是建议职业暴露水平至少应有的装备�?�参见第3�?8�?11�?
分以便估计职业暴露水平�??
甲醛浓度高于职业暴露水平1倍，但低�?10倍﹕使用罩盖整个脸的空气�?化防毒面罩及
HEPA粒子过滤器，并加特别核准用于预防甲醛的筒或滤毒罐，或罩盖整个脸的电动�?
气净化防毒面罩及HEPA粒子过滤器，并加特别核准用于预防甲醛的筒或滤毒罐。空�?
�?化部件必须有结束服务寿命的显示器，或必须有一个更换时间表的文件�?�否则使�?
输�?�的空气�?
浓度高于职业暴露水平10倍，但低于职业暴露水平的100倍或IDLH﹕使用C型罩盖整�?
脸�?�在压力要求或不断输送空气的防毒面罩�?
浓度高于IDLH水平或浓度不�?(例如在紧急情况下)﹕使用罩盖整个脸、在正压状�?�下
运作的独立呼吸装置�?�含辅助正压独立呼吸装置逃生系统的C型正压罩盖整个脸、输�?
空气的防毒面罩�??
逃生﹕使用正压罩盖整个脸的独立呼吸装置或罩盖整个脸�?�在下巴或前或后安装工业
尺寸、特别核准用于预防甲醛特别核准用于预防甲醛的滤毒罐�??

暴露指南
重量% ACGIH ACGIH ACGIH OSHA OSHA OSHA Celanese Mexico Mexico Mexico
成分及化学文摘服�? 成分及化 TWA STEL CEILING TWA STEL CEILING WEL TWA STEL CEILING
处号�? 学文摘服 (工作场所
务处号�?? 接触限度)
甲醛 50-00-0 37 - 37.5 - - 0.3 ppm 0.75 ppm 2 ppm - 0.75 ppm - - 2 ppm
(TWA); 2
ppm (STEL)
甲醇 67-56-1 9 - 12 200 ppm 250 ppm - 200 ppm - - - 200 ppm 250 ppm -
甲酸 64-18-6 0.02 5 ppm 10 ppm - 5 ppm - - - 5 ppm - -

成分及化学文摘服务处号�?? 重量% 1990 NIOSH IDLH 1994 NIOSH IDLH
成分及化学文摘服务处 (Recognized by OSHA)
号�??
甲醛 50-00-0 37 - 37.5 30 ppm 20 ppm
甲醇 67-56-1 9 - 12 25,000 PPM 6000 ppm
甲酸 64-18-6 0.02 30 PPM 30 ppm

Comments: Celanese 公司根据对所有现有资料的科学评价，决定对甲醛不采用ACGIH上限值�??
Celanese 公司对甲醇采�? ACGIH TLV�?

9. 物理和化学特�?

外貌: 透明、无色液体�??

味道: 强烈、刺鼻�?�独氐钠�?丁�??蘋DOR020
淡辛辣�?�脂肪酸气味�?
o
pH (1% soln in water @ 25 C): 3-6

Vapor Pressure: 25 mmHg @ 25 deg C

Vapor Density (Air=1 @ 20 C): Formaldehyde: 1.04 (calculated)
Water: 0.62 (calculated)
Methanol: 1.11 (calculated)
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运输紧�?�情�?:703 527 3887 (USA) CHEMTREC, collect calls accepted, 24 hrs/day
6 of 17
产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004

Boiling Point (760 mmHgA): 96 C (204.8 F) - 97 C(206.6 F)

Freezing Point: �?13 C (55 F)以下，固态甲醛聚合物逐渐形成。冰�? �? 0
C (32 F)以下出现�?

Solubility in Water @ 20 C: complete

Specific Gravity: 1.086 @ 25 deg C

Molecular Weight:: Formaldehyde: 30.0
Water: 18
Methanol: 32.0

10. 稳定性与反应�?

稳定�?: 稳定�?

应避免的情况: 避免高热、火焰�?�火花和其它火源�?

应避免的材料: 避免接触氢氧化钠、石灰和其它强碱、钠、钾和其它强碱金属�?�盐酸�?�硫酸和其它�?
无机酸�?�氮氧化物�?�胺和氧化剂如过氧化物�?�硝酸�?�高氯酸、三氧化铬�?�苯酚或尿素
�?

危险易燃或分解产品：热分解产品可能含有碳的氧化物�?

危险聚合作用: 不会产生危险的聚合作用�??

11. 毒�?�资�?

Component Toxicological Information

成分及化学文摘服务处号�?? 甲醛

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运输紧�?�情�?:703 527 3887 (USA) CHEMTREC, collect calls accepted, 24 hrs/day
7 of 17
产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
Acute Exposure: Toxicity information on the solution is generally not
available. Information on the solution components is listed next.

Oral LD50: 800mg/kg (rats); slightly toxic to animals.

Inhalation LC50: 474ppm (rats,4 hrs.); moderately toxic to animals.

Skin: Severely irritating/corrosive to rabbit skin depending on exposure
duration and concentration; moderately toxic to animals (LD50, rabbits:
270mg/kg); causes skin sensitization in humans and guinea pigs.

Eye: Severely irritating to rabbit eyes.

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运输紧�?�情�?:703 527 3887 (USA) CHEMTREC, collect calls accepted, 24 hrs/day
8 of 17
产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
Mutagenicity: Genotoxic potential was noted in a variety of in vitro
systems. Results in vivo have been mixed probably due to the presence of
metabolic processes for detoxifying.

Carcinogenicity: Oral-Formaldehyde was not carcinogenic in several well-
conducted rodent lifetime drinking water studies. Repeated dermal-topical
application on mice has not indicated carcinogenic potential. Inhalation-
Rats and mice were exposed to 2.0, 5.6, or 14.3 ppm formaldehyde for
6hrs/day, 5 days/week for 24 months. In rats no treatment-related tumors
were seen at 2 ppm while at 5.6 ppm 1% had nasal tumors and at 14.3 ppm
43% had nasal tumors. In mice no treatment-related tumors were observed
at 2 ppm or 5.6 ppm while 1% had nasal tumors at 14.3 ppm. IARC: Group I,
Carcinogenic to Humans, based on sufficient human (nasopharyngeal cancer)
and experimental animal data. Formaldehyde is listed as an OSHA
carcinogen. Formaldehyde is listed as an anticipated carcinogen by the
NTP.

Hauptmann, et. al. (2004) have reported a statistically significant dose-
related increase in the incidence of nasopharyngeal tumors in a large
cohort of formaldehyde exposed workers. In another study by Hauptmann,
et. al. (2003) based upon the same cohort, a statistically significant
dose-related increase of leukemia mortality was observed. However, this
increase was seen only for a peak exposure metric and the rate of leukemia
mortality was less than that of the unexposed general population. In
addition, the Hauptmann et. al. (2003) results are not consistent with the
findings of Coggon et. al. (2003). Coggon et. al. found no association
between formaldehyde exposure and leukemia incidence in a large cohort of
U.K. workers with estimated formaldehyde exposures higher than the
Hauptmann et. al. (2003) study. A recent NIOSH study (Pinkerton, et. al.
2004) based on a cohort of formaldehyde exposed garment workers reported
only a marginal association with leukemia incidence. Experimental data
linking formaldehyde exposure with toxicity in organs, including the bone
marrow, remote from the portal of entry is lacking. Also, an established
mechanism for induction of leukemia by formaldehyde is not available.
Furthermore, formaldehyde inhalation by rats in several well-conducted
cancer bioassays did not induce leukemia.

Reproductive/Developmental Effects: In a developmental toxicity study with
mice dosed orally by gavage at 74, 148 or 185 mg/kg/day, no fetotoxic or
teratogenic effects were seen. In a developmental toxicity study with
rats exposed via inhalation to 2, 5 or 10ppm formaldehyde, treat-related
developmental effects were not observed. In a reproduction study, dogs
received the equivalent of 9.4 mg/kg/day of formaldehyde in feed during
days 4-56 after mating without adverse reproductive effects.

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MSDS 号码: 155
材料号码: 80155
公布日期�? 06/28/2004
Repeated Exposure: Inhalation exposure (6hrs./day;5 days/week;13 weeks)
of rats resulted in nasal tissue irritation at 10 or 20ppm, but not at
2ppm. Monkeys exposed for 26 weeks (22hrs./day;7 days/week) had nasal
irritation at 3ppm but not at 1ppm. Oral exposure of rats to formaldehyde
in the drinking water at a dose equivalent to 82-109 mg/kg/day over a
lifetime resulted in stomach tissue irritation while a dose of 15-21
mg/kg/day was without effect.
成分及化学文摘服务处号�?? 甲醇
Acute Exposure: Toxicity information on the solution is generally not
available. Information on the solution components is listed next.

Oral LD50: 6.2-12.9g/kg (rats); practically nontoxic to animals. However,
based on human exposure reports, a small amount (usually two or more
ounces) can cause mental sluggishness, nausea and vomiting leading to
severe illness, and may produce adverse effects on vision with possible
blindness or death if treatment is not received.

Inhalation LC50: 64000ppm (rats,4 hrs.); practically nontoxic to animals.
Based on human exposure reports, levels substantially above the TLV cause
stupor, headache, nausea, dizziness, unconsciousness and may produce
adverse effects on vision.

Skin: Irritating to rabbit skin. Severity depends on the quantity
administered and exposure period and is related to the defatting
properties of methanol; slightly toxic to animals (minimum lethal dose,
monkeys: 1.6g/kg; LD50, rabbits:16g/kg). Based on human exposure reports,
prolonged and repeated skin contact with methanol-soaked material has
produced toxic effects including vision effects and death.

Eye: Severely irritating to rabbit eyes.

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Mutagenicity: Methanol - Not genotoxic in most in vitro assays. Not
genotoxic in vivo in mice exposed via inhalation up to 4000ppm (6hrs./day
for 5 days) and subsequently examined for cytogenetic effects.

Carcinogenicity: Methanol - Inhalation-Not carcinogenic in lifetime
inhalation studies (reported in limited detail) in rats and mice at
concentrations of 10-1000ppm. Dermal-Not carcinogenic in mice exposed
dermally to 0.02ml/day, 2 days/week over a lifetime in a study of limited
quality.

Reproductive/Developmental Effects: Methanol - In an inhalation
developmental toxicity study, rats were exposed 6hrs./day to 5000, 10000
or 20000ppm vapors. A significant teratogenic response was seen at
20000ppm. Fetotoxicity was noted at 10000ppm, but not at 5000ppm. In an
inhalation developmental toxicity study, mice were exposed 7hrs./day to
2000, 5000 or 10000ppm vapors. Methanol caused developmental toxicity at
all levels. Oral administration of methanol via gavage at 1.3, 2.6 or 5.2
ml/kg to rats resulted in developmental toxicity at all levels.

Repeated Exposure: Methanol - Inhalation exposure (6hrs./day; 5days/week)
of monkeys to vapor concentrations of 500, 2000 or 5000ppm for 4 weeks did
not result in any treatment-related effects. Monkeys exposed to methanol
vapors of 10, 100 or 1000ppm for 22hrs./day for up to 2.5yrs. showed
changes in the liver, kidney and nervous system at 1000ppm (limited
details reported). Rats exposed by oral gavage to 100, 500 or
2500mg/kg/day methanol for 90days exhibited only effects on organ weight
(brain) and serum enzymes (SGPT,AP) at the high dose.

成分及化学文摘服务处号�?? 甲酸

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Acute Exposure: The toxicity of formic acid in concentrated form is
related to its irritant properties at the site of contact, e.g., nasal
passage irritation after inhalation exposure; skin irritation after dermal
exposure; gastrointestinal irritation after oral exposure (bolus
administration). As is the case for many acids, toxicity (irritation)
decreases as the concentration in aqueous solutions decreases. Formic
acid occurs in a variety of plants, fruits and mammalian tissues. It is
an important, normal body metabolite. Its safety as a food ingredient has
been reviewed by the FDA.

Oral LD50: 1100-1850 mg/kg (rats); slightly toxic to animals.

Inhalation LC50: Estimated to be >500 ppm (rats,6 hrs.) based on 60%
survival of rats exposed to 500 ppm for 10 days; slightly toxic to
animals. Vapors are severely irritating to the respiratory tract based on
human exposure information.

Skin: Concentrated solutions of formic acid are corrosive to skin.

Eye: Concentrated solutions of formic acid are corrosive to the eyes.
Vapors are severely irritating to the eyes.

Mutagenicity: Formic acid was not mutagenic in the Ames Test with or
without metabolic activation. It did not induce sister-chromatid
exchanges, with or without metabolic activation, in hamster V79 cells.
Positive results were reported for formic acid in the Drosophila SLRL test
and in tests for chromosomal aberrations in Chinese hamster ovary cells.
However, in both tests it was noted that neutralizing the acidic pH of the
test environment eliminated the mutagenic responses. It was concluded
that formic acid by itself is not mutagenic, but that testing at
concentrations which produce nonphysiological pH levels results in "false
positive" responses due to perturbations in the test systems. The weight
of the evidence indicates that formic acid is not mutagenic.

Carcinogenicity: No information.

Reproductive/Developmental Effects: To screen for potential reproductive
toxicity, sperm morphology/density/motility and vaginal cytology
examinations were performed on rats and mice administered formic acid at
0, 8, 32 or 128 ppm via inhalation (6 hrs./day; 5 days/week) for 13 weeks.
Potential impact on the length of the estrous cycle was also monitored.
There were no adverse effects in rats or mice.

---------------------------------------------------------------------------------------------------------------------------------

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MSDS 号码: 155
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Repeated Exposure: Inhalation exposure (6hrs./day; 5days/week) of rats and
mice was conducted at vapor concentrations of 0, 31, 62.5, 125, 250 or 500
ppm for 2 weeks. At 500 ppm, 60% survival was reported for rats. At 500
ppm and 250 ppm, the survival rates for mice were 0% and 90%,
respectively. No deaths were reported at other dose levels. Microscopic
examination of tissues revealed irritation of the nasal passages in rats
and mice exposed to 62.5 ppm and higher concentrations. Severity
increased in a dose-related manner. This was a range-finding study to set
dose levels for the 13-week study discussed next.

Inhalation exposure (6hrs./day; 5days/week) of rats and mice was
conducted at vapor concentrations of 0, 8, 16, 32, 64 and 128 ppm for 13
weeks. At 128 ppm, 85% survival was reported for mice. No other effects
were noted on survival at other dose levels. Microscopic examination of
tissues revealed irritation of the nasal passages (minimal to mild
severity) primarily in animals exposed to 128 ppm. The NOAEL (no-
observed-adverse-effect level) was 32 ppm.

Formic acid was administered orally to rats in drinking water for 2 to 27
weeks at doses of 8.2, 10.2, 90, 160 or 360 mg/kg/day. No mortalities
were reported. Food consumption and growth were inhibited by formic acid
at 360 mg/kg/day, but no adverse effects were seen at the lower doses. In
another study, lower weight gain was reported in rats receiving formic
acid in the diet at 0.5 and 1.0% or in drinking water at 0.5 or 1.0%.

12. 生�?�资�?

Component Ecological Information

成分及化学文摘服务处号�?? 甲醛
Ecotoxicity: Formaldehyde exhibits slight acute toxicity to various fish
species. The 24-, 48- and 96-hr. LC50 values (bluegill sunfish, trout,
bass, salmon, catfish, carp, golden orfe) are in the range 10-1000ppm.
Algae and some invertebrates appear more susceptible e.g., acute toxicity
occurs in green algae at 0.3-0.5ppm and in the water flea (daphnids) at 2-
52ppm (24/48-hr. EC50). Formaldehyde has bactericidal properties at low
levels (EC50, E. coli=1ppm).

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材料号码: 80155
公布日期�? 06/28/2004
Environmental Fate: The short atmospheric half-life, the low n-
octanol/water partition coefficient and the ability of animals &
microorganisms to rapidly biodegrade formaldehyde are expected to lead to
its ready removal if released into the environment.
Degradation: Formaldehyde in aqueous effluent is degraded by activated
sludge and sewage in 48-72 hr. In a die-away test with lake water,
degradation was complete in 30 hrs. under aerobic conditions and 48 hrs.
under anaerobic conditions. Atmospheric photochemical degradation is
rapid with estimated half-lives of 19hrs. or less.

Bioaccumulation: The log n-octanol/water partition coefficient is 0.35.
This suggests that formaldehyde has relatively low potential to
bioaccumulate.

成分及化学文摘服务处号�?? 甲醇
Ecotoxicity: Toxicity information on the solution is generally not
available. Information on solution components is listed next.

Methanol exhibits low acute toxicity to aquatic species. The 24-, 48- and
96-hr. LC50 values for various fish species (bluegill sunfish, fathead
minnows, rainbow trout, goldfish, carp, bleak, creek chub) are in the
range 1700-28100ppm. The 18-, 24- and 48-hr. EC50 values for the water
flea (daphnids) are in the range 10000-24500ppm. The 18-hr. LC50 for
grass shrimp is 21900ppm and the 24-hr. LC50 for brine shrimp is
>10000ppm. Cell multiplication was inhibited after 8 days exposure to
8000ppm and 530ppm in the green algae (Scenedesmus quadricauda) and blue-
green algae (Anacystis aeruginosa), respectively.

Environmental Fate: The ability of animals and microorganisms to rapidly
biodegrade methanol coupled with its low n-octanol/water partition
coefficient is expected to lead to its rapid removal if released into the
environment.

Degradation: Under aerobic conditions methanol is readily biodegradable.
The 5-Day BOD values are 48-83% of COD. Biodegradation also occurs under
anaerobic conditions, e.g. 83-91% degradation in a marine water/sediment
system after 3 days. Atmospheric photochemical degradation (half-life) is
estimated to be be 17.8days. Volatilization half-lives of 4.8days and
51.7days have been estimated for a model river and a model pond,
respectively.

Bioaccumulation: The log n-octanol/water partition coefficient for
methanol is -0.77. This suggests that methanol has low potential to
bioaccumulate.
成分及化学文摘服务处号�?? 甲酸

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产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
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材料号码: 80155
公布日期�? 06/28/2004
Ecotoxicity: Formic acid exhibits low to slight acute toxicity to aquatic
species.

Fish (Leuciscus idus) 48-hr. LC50 = 122 ppm.
Fish (Leuciscus idus) 96-hr. LC50 = 46 to100 ppm.
Fish (Lepomis gibbosus) 24-hr. LC50 = 175 to 5000 ppm.

Crustacean (Daphnia magna) 48-hr. EC50 = 120 to 151.2 ppm.
Crustacean (Daphnia magna Straus) 24-hr. EC50 = 34.2 ppm.
Crustacean (Daphnia magna Straus) 48-hr. EC50 = 34.2 ppm.

Arthropod (Artemia salina) 24-hr. LC50 = 410 ppm.

Algae (Scenedesmus quadricauda) 96-hr. Toxicity Threshold = 100 ppm.
Algae (Scenedesmus subspicatus) 72-hr. EC50 = 26.9 ppm.
Algae (Scenedesmus subspicatus) 96-hr. EC50 = 25 ppm.

Bacteria (Escherichia coli) 24-hr. NOEC = 1000 ppm.
Bacteria (Pseudomonas putida) 17-hr. EC50 = 46.7 ppm.
Bacteria (Belebtschlamm species) 30-min. EC0 = 1000 ppm.

Environmental Fate:

Degradation: Formic acid was determined to be "readily biodegradable" in
two separate aerobic tests according to OECD Guideline 301 E: Ready
Biodegradability: Modified OECD Screening Test. In six other aerobic
tests using various methods, biodegradation of formic acid ranged from
40.5 to 80.5 percent after 5 days. Seventy percent aerobic biodegradation
occurred after only 1 day using the Warburg technique with activated
sludge. Photodegradation (indirect photolysis) of formic acid occurs in
air and water. The half-life in air is 35.7 days. The half-life in water
is 0.9 year.

Bioaccumulation: The calculated values for the log octanol/water partition
coefficient of formic acid range from -1.55 to -0.22. The measured log
octanol/water partition coefficient is -0.54. These data indicate that
formic acid has low potential to bioaccumulate.

---------------------------------------------------------------------------------------------------------------------------------

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材料号码: 80155
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13. 丢弃时的注意事项

根据州和当地对危险废料规定处理溢出材料�?�建议方法是在联邦或州准许的处理设施焚化或作生物处理。请注意�?
此数据仅应用在所制�?�的材料；加工�?�使用或污染可能会使本资料不适当、不正确或不完整�?

请注意﹕这一处理与丢弃资料也可能适用于空容器、垫和残渣�?�州或当地规定或限制非常复杂，�?�且可能异于联邦
规定。本资料的目的是协助适当的处理与丢弃；处理与丢弃的最后责任由废料的拥有人负责。参见�?�第9部分，物�?
与化学特性�?��??

环境保护�?危险废料代码�? U122

14. 运输资料

US Department of Transportation:
UN/NA Number: UN 1198
Shipping name: FORMALDEHYDE, SOLUTIONS, FLAMMABLE
Hazard class: 3
Subsidiary hazard: (8)
Packing Group: PG III
DOT Reportable Quantity (RQ): 100 lb/45.4 kg (FORMALDEHYDE)
5000 lb/2270 kg (METHANOL)
Emergency Response Guide: 132

ICAO/IATA:
IATA UN Number: UN 1198
Proper Shipping Name: FORMALDEHYDE, SOLUTIONS, FLAMMABLE
Hazard Classification: 3 (Flammable Liquid)
Subsidiary Hazard: 8 (Corrosive Material)
Packing group: III
Label: (Flammable Liquid) (Corrosive)

IMDG:
International Marine UN Number: UN 1198
Proper Shipping Name: FORMALDEHYDE, SOLUTIONS, FLAMMABLE
Hazard Class: 3 (Flammable Liquid)
Subsidiary Hazard: 8 (Corrosive Material)
Packing Group: III
闪点(测试方法)�? 56 C (133 F) to 64 C (147 F) (SETA)

---------------------------------------------------------------------------------------------------------------------------------

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产品名称�? 37% Formaldehyde/ 9-12% Methanol, solution
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材料号码: 80155
公布日期�? 06/28/2004

Trade Information
Schedule B Code (export): 2912.11.0000
Harmonization Code (import): 29121100

15. 法规资料

INTERNATIONAL REGULATIONS
化学详细目录
列于下列国家的化学详细目录或符合豁免资格:
AUSTRALIA,CHINA,CANADA,EUROPE,KOREA,PHILIPPINES, JAPAN

16. 其它资料

提供单位: 产品指导�?
Celanese 公司

危险等级本资料仅供经NFPA �?/�? HMIS 系统训练的人员使用�??

NFPA: Health: 3 Flammability: 2 Reactivity: 0

HMIS: Health: 3* Flammability: 2 Reactivity: 0

下列资料是最新版本MSDS出版后的 The following sections have been revised since the last issue of this
修正: MSDS.

9. 物理和化学特�? 3. 危险识别 11. 毒�?�资�?
此处�?含资料之精确性为我们�?大限度之�?知�?�我们并不表示或保证此处�?列之危险为仅有之危险。就你所购得之材料的安全使用
或与其它物质�?并使用，Celanese公司不提供任何明确或暗示之保用�?�其它材料可加重本材料的危险性，本材料也可加重其它材�?
的危险�?��?�本材料可从直接或间接由其制成的气体、液体或固体材料中释出�?�使用�?�对确定本材料是否�?�用于任何用途及�?计划�?
使用方式负完全责任�?�使用�?�必须符合所有有关安全及健康标准�?
材料安全资料单由Celanese公司在互联网上提供作为对客户的一项服务�?�拥有互联网的材料安全资料单�?

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