Material Safety Data Sheet
Revision: 02/23/2004
Hazard information is provided for compliance with both the UK Chemicals
(Hazard Information and Packaging) (CHIP) Regulations and the US Hazard
Communication Standard (HCS)
IDENTIFICATION OF THE PRODUCT NAME: PRODUCT CODE: EEC NUMBER:
SUBSTANCE/PREPARATION Pepsin 20010 232-629-3
AND COMPANY Source: Porcine Stomach
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Outside USA & Canada 703 527 3887
COMPOSITION/
HAZARDOUS COMPONENTS HAZARD CAS NO. %WT TLV CHIP R & S Phrases
Pepsin 9001-75-6 ~90% --- R:36/37/38 Irritating to eyes,
respiratory system and skin.
R:42 May cause sensitization by
inhalation.
S:22 Do not breathe dust.
S:24 Avoid contact with skin.
S:26 In case of contact with eyes, rinse
immediately with plenty of water and
seek medical advice.
S:36/37 Wear suitable protective
clothing and gloves.
HAZARDS IDENTIFICATION CHIP
Harmful
HCS
Irritant & Allergen
FIRST-AID MEASURES EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and
wash before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give
oxygen. If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate
medical attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mouth to an unconscious person.
FIRE-FIGHTING INFORMATION Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self
contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. Pepsin, which is
an animal protein, is believed to be combustible. Pepsin powder may, on being transferred from container to
container, generate static electric charge, which could discharge violently. Emits toxic fumes under fire
conditions. NFPA Rating: H=1 F=1 R=0.
Flash Point = No data available.
ACCIDENTAL RELEASE MEASURES Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and
NIOSH-approved respirator. Collect in a manner that does not create dust and place in a suitable waste
container. Avoid contact of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and
NIOSH-approved respirator. Avoid contact of material with skin or eyes. Pepsin powder may, on being
transferred from container to container, generate static electric charge, which could discharge violently. Use
adequate ventilation. Store dessicated at -20掳C. Protect from sunlight. HMIS Rating: H=1 F=1 R=0.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the information
contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet must be determined by the user
to be in accordance with appropriate applicable regulations
For Further Asia Pacific Canada Former Soviet Union Japan Norway Spain USA
Information, +852 2811 8693 1 800 463 5800 +7 (095) 232 0250 81 3 5331 9337 63 89 23 10 935 944 950 USB Corporation
contact your (216) 765-5000
local USB If purchased from
Australia Central and East Europe France Latin America Portugal Sweden
Authorized +61 2 9894 5188 +43 1 982 3826 0169 18 28 00 +55 11 3667 5700 01 417 70 35 018 164000 Amersham Biosciences
distributor, use 1 800 526 3593
Amersham Austria Denmark Germany Middle East and Africa South East Asia Switzerland
Biosciences 01 576 0616 10 +45 4516 2400 07 61 49 03 0 +30 (1) 96 00 687 60 3 724 2080 01 802 81 50
Belgium Finland Italy Netherlands South East Europe UK
0800 73888 358 (9) 512 3940 02 27322 1 0165 580 410 +43 (1) 982 3826 0800 515313
MSDS information may be continued on back of page.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and
NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection.
Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of
material with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust,
vapors or mists. Access to a safety shower and eye-wash.
PHYSICAL AND CHEMICAL Appearance: Lyophilized powder Boiling Point: No data available
PROPERTIES Vapor Pressure: No data available Vapor Density: No data available
Solubility (Water): Soluble Specific Gravity: No data available
Percent Volatile: No data available Evaporation Rate: No data available
Chemical formula: No data available Melting Point: No data available
STABILITY AND REACTIVITY Product is stable. Avoid heating above 70掳C. Avoid alkaloids. Protect from sunlight. Incompatible with strong
oxidizing agents, alcohols, tannin, alkaline substances and salts of heavy metals. Emits toxic fumes when
heated to decomposition. Hazardous polymerization will not occur.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOSURE:
EYES: Contact may cause irritation. Repeated exposure may cause sensitization.
SKIN: Contact may cause irritation, dermatitis and hypersensitive individuals may experience an allergic
reaction. Repeated exposure may cause sensitization. Proteolytic enzyme; degrades protein; may cause
tissue irritation.
INHALATION: May cause irritation to mucous membranes and upper respiratory tract. Hypersensitive
individuals may experience an allergic reaction. Repeated exposure may cause sensitization and asthma.
INGESTION: May cause irritation of the mouth, throat esophagus and gastrointestinal tract. May cause
allergic reaction characterized by a rash. Repeated exposure may cause sensitization and asthma.
ADDITIONAL INFORMATION:
Pepsin is a proteolytic enzyme which degrades proteins. May be harmful by inhalation, ingestion or skin
absorption. May cause allergic respiratory and skin reactions.
Mutation data listed in RTECS under SC6132000.
Definition(s): RTECS = Registry of Toxic Effects of Chemical Substances.
ECOLOGICAL INFORMATION No information available.
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: No applicable information.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 - This material does not have an RQ or TPQ.
SARA 313 -This material is not reportable under 313.
EPA TSCA Section 8(b) - Chemical Inventory.
Exposure Limits - Not established.
California Proposition 65 - No applicable information.
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